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The map label for this gene is thiL [H]

Identifier: 148360618

GI number: 148360618

Start: 905056

End: 906012

Strand: Direct

Name: thiL [H]

Synonym: LPC_2564

Alternate gene names: 148360618

Gene position: 905056-906012 (Clockwise)

Preceding gene: 148360619

Following gene: 148360617

Centisome position: 25.31

GC content: 42.74

Gene sequence:

>957_bases
ATGAATGAATTTACCCTGATTGATCATTATTTTAAATCCATCCCATGCAAGAGAAATGATGTCCTTTTTGGGATAGGGGA
TGATGCTGCTTGCTTGCAGGTTCCCGATGGAATGCATTTGCTAGTCAGCACGGATACTTTGGTTTCAGGCATTCATTTCC
TACCGCAATGGGATCCCTATGATATTGCCTGCAAGGCAGTAATGGTCAATATTAGTGACATGGCTGCCATGGGCTCACAG
CCATGTTGGGTGACTCTTGCATTGACCTTGCCCGAATTGAATCAGAGTTGGCTTGATTCCTTCGCGAGAGGGATAAAAGA
CTCTCTTGGCTTATATAATGTGGATCTGATCGGTGGTGACACGACCAAAGGCCCGTTATCAATCACTTTGACCATCATGG
GGCTCACACCTCAGGGACAAGCAATCAGACGTTGTGGCGCACAAGCGGGTGACGCGATTATAGTTTCCGGTGAATTGGGG
GCTGCGGGTCTGGCTGTAAAATTGCTGGATGGGCATAAAAAAGTGAATGCAAAAGATAAAATAGAATTAATGAATAAACT
ATTACATCCTAAACCACGGGTGGATTTATGCCATTTGCTTAGAAAATATGCTACTTCAGCGATTGATATCTCTGATGGGT
TAGGCGCTGATTTAAATCATATTTGCGTCGCAAGTGGTGTTGGGGCCAACTTGTTTGAAGAAGCAATACCCAGGCATCCT
TTATTGAATCAATATTGTCCTGAACAAGCCCTTGACTTGGCTCTTTCAGGAGGTGATGATTACGAGTTATGTTTTACAGT
TTCAACACAACAGCTGGATTCTTTTAATCGGGATCTTCAAAAAGAAAATCTGATCTGTTTTCCCATCGGTGTGATAGAGG
AGAAACCAGGATTAAGAATACAATCAGCTGATAGTCCAAGTAAAGAATTGCAACCCAGAGGCTATTCACATTTTTAA

Upstream 100 bases:

>100_bases
TTGACTAAAGAGTTTGGTTCACAAGAGGGATATCGTTACGTTAATGGGGTATTGAATAATTTGGCAAAACAGGTTCGCTC
TGTTGAAGTCAGTCTTGATA

Downstream 100 bases:

>100_bases
ATCCCGCCTCTATAGTATGATAATAAAAATTAAAGACAAAATTCGATTCTAAAGTGATGTGATAGCGATATTTAGGTTGA
GGAGCAAATATGAACCAAGT

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MNEFTLIDHYFKSIPCKRNDVLFGIGDDAACLQVPDGMHLLVSTDTLVSGIHFLPQWDPYDIACKAVMVNISDMAAMGSQ
PCWVTLALTLPELNQSWLDSFARGIKDSLGLYNVDLIGGDTTKGPLSITLTIMGLTPQGQAIRRCGAQAGDAIIVSGELG
AAGLAVKLLDGHKKVNAKDKIELMNKLLHPKPRVDLCHLLRKYATSAIDISDGLGADLNHICVASGVGANLFEEAIPRHP
LLNQYCPEQALDLALSGGDDYELCFTVSTQQLDSFNRDLQKENLICFPIGVIEEKPGLRIQSADSPSKELQPRGYSHF

Sequences:

>Translated_318_residues
MNEFTLIDHYFKSIPCKRNDVLFGIGDDAACLQVPDGMHLLVSTDTLVSGIHFLPQWDPYDIACKAVMVNISDMAAMGSQ
PCWVTLALTLPELNQSWLDSFARGIKDSLGLYNVDLIGGDTTKGPLSITLTIMGLTPQGQAIRRCGAQAGDAIIVSGELG
AAGLAVKLLDGHKKVNAKDKIELMNKLLHPKPRVDLCHLLRKYATSAIDISDGLGADLNHICVASGVGANLFEEAIPRHP
LLNQYCPEQALDLALSGGDDYELCFTVSTQQLDSFNRDLQKENLICFPIGVIEEKPGLRIQSADSPSKELQPRGYSHF
>Mature_318_residues
MNEFTLIDHYFKSIPCKRNDVLFGIGDDAACLQVPDGMHLLVSTDTLVSGIHFLPQWDPYDIACKAVMVNISDMAAMGSQ
PCWVTLALTLPELNQSWLDSFARGIKDSLGLYNVDLIGGDTTKGPLSITLTIMGLTPQGQAIRRCGAQAGDAIIVSGELG
AAGLAVKLLDGHKKVNAKDKIELMNKLLHPKPRVDLCHLLRKYATSAIDISDGLGADLNHICVASGVGANLFEEAIPRHP
LLNQYCPEQALDLALSGGDDYELCFTVSTQQLDSFNRDLQKENLICFPIGVIEEKPGLRIQSADSPSKELQPRGYSHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=273, Percent_Identity=51.6483516483517, Blast_Score=253, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34545; Mature: 34545

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFTLIDHYFKSIPCKRNDVLFGIGDDAACLQVPDGMHLLVSTDTLVSGIHFLPQWDPY
CCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCCEEEEECHHHHHHHHHCCCCCCH
DIACKAVMVNISDMAAMGSQPCWVTLALTLPELNQSWLDSFARGIKDSLGLYNVDLIGGD
HHEEEEEEEEHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCC
TTKGPLSITLTIMGLTPQGQAIRRCGAQAGDAIIVSGELGAAGLAVKLLDGHKKVNAKDK
CCCCCEEEEEEEEEECCCCHHHHHCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHH
IELMNKLLHPKPRVDLCHLLRKYATSAIDISDGLGADLNHICVASGVGANLFEEAIPRHP
HHHHHHHHCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCEEEECCCCHHHHHHHCCCCC
LLNQYCPEQALDLALSGGDDYELCFTVSTQQLDSFNRDLQKENLICFPIGVIEEKPGLRI
CHHHHCCHHHHHEEECCCCCEEEEEEECHHHHHHHHHHHHHCCEEEEEEEEECCCCCCEE
QSADSPSKELQPRGYSHF
ECCCCCHHHCCCCCCCCC
>Mature Secondary Structure
MNEFTLIDHYFKSIPCKRNDVLFGIGDDAACLQVPDGMHLLVSTDTLVSGIHFLPQWDPY
CCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCCEEEEECHHHHHHHHHCCCCCCH
DIACKAVMVNISDMAAMGSQPCWVTLALTLPELNQSWLDSFARGIKDSLGLYNVDLIGGD
HHEEEEEEEEHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCC
TTKGPLSITLTIMGLTPQGQAIRRCGAQAGDAIIVSGELGAAGLAVKLLDGHKKVNAKDK
CCCCCEEEEEEEEEECCCCHHHHHCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHH
IELMNKLLHPKPRVDLCHLLRKYATSAIDISDGLGADLNHICVASGVGANLFEEAIPRHP
HHHHHHHHCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCEEEECCCCHHHHHHHCCCCC
LLNQYCPEQALDLALSGGDDYELCFTVSTQQLDSFNRDLQKENLICFPIGVIEEKPGLRI
CHHHHCCHHHHHEEECCCCCEEEEEEECHHHHHHHHHHHHHCCEEEEEEEEECCCCCCEE
QSADSPSKELQPRGYSHF
ECCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]