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The map label for this gene is ccmG [H]

Identifier: 148360492

GI number: 148360492

Start: 1042372

End: 1042905

Strand: Direct

Name: ccmG [H]

Synonym: LPC_2432

Alternate gene names: 148360492

Gene position: 1042372-1042905 (Clockwise)

Preceding gene: 148360493

Following gene: 148360491

Centisome position: 29.15

GC content: 40.45

Gene sequence:

>534_bases
ATGAAAAAAGTAGGATGGCGTGTTATTCCTATCGCTATTTTTTGTCTTTTATGTTTTTTCCTCTGGCGAGGTTTATCTTT
GGATCCCCATCATTTGCCTTCAGCTCGAATTGGAAAGCCATTGCCAGACTTTGCCTTACCAGAGTTGCAAAATCCCGATT
CTACTTTTAGTGCAATAAACTTTCATAATCAGGTCGTTTTGCTTAATGTCTGGGCAAGTTGGTGTGAGGCTTGCGTTGAA
GAGCAAGTATTTATGTTGCAACTCGCAAGAGAAGGCGTACCTATCTATGGTTTAAATTATAAAGACAATCCAGAGCACGC
GAGAGCATGGCTTTCACAATGGGGGAATCCTTATCGACTCATAGGCCAGGATTCAGAAGGTAAAGTCGCTATTGACTTAG
GTGTATATGGGGCGCCTGAAACTTTTGTCATTGATAAGAAAGGAATAGTCCGCTACAGGCATGTCGGGATAATGAATCAG
AAAACCTGGTTAACTGATATTTTACCTTTAATGAGGAATTTGGAGAAATCATAA

Upstream 100 bases:

>100_bases
GCGGATTTATGATTTTAGCCGGAGGCGTTTTGGCATTAACAGATAGAAGGTATTACAGAAAAAGACAAGTAATGGTAATG
GCAGGGCAGGAGATCAAGAT

Downstream 100 bases:

>100_bases
TGAGAGTATTCCACTTCTGTTTTAAGGTGATTTTATTGCTGCTATTAGTATCCGTTGCGTTTGCAAATAGTATGTATCCA
TTGGACTCAGCAAGAAAAGA

Product: cytochrome C biogenesis protein

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MKKVGWRVIPIAIFCLLCFFLWRGLSLDPHHLPSARIGKPLPDFALPELQNPDSTFSAINFHNQVVLLNVWASWCEACVE
EQVFMLQLAREGVPIYGLNYKDNPEHARAWLSQWGNPYRLIGQDSEGKVAIDLGVYGAPETFVIDKKGIVRYRHVGIMNQ
KTWLTDILPLMRNLEKS

Sequences:

>Translated_177_residues
MKKVGWRVIPIAIFCLLCFFLWRGLSLDPHHLPSARIGKPLPDFALPELQNPDSTFSAINFHNQVVLLNVWASWCEACVE
EQVFMLQLAREGVPIYGLNYKDNPEHARAWLSQWGNPYRLIGQDSEGKVAIDLGVYGAPETFVIDKKGIVRYRHVGIMNQ
KTWLTDILPLMRNLEKS
>Mature_177_residues
MKKVGWRVIPIAIFCLLCFFLWRGLSLDPHHLPSARIGKPLPDFALPELQNPDSTFSAINFHNQVVLLNVWASWCEACVE
EQVFMLQLAREGVPIYGLNYKDNPEHARAWLSQWGNPYRLIGQDSEGKVAIDLGVYGAPETFVIDKKGIVRYRHVGIMNQ
KTWLTDILPLMRNLEKS

Specific function: Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=176, Percent_Identity=43.75, Blast_Score=149, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 20260; Mature: 20260

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVGWRVIPIAIFCLLCFFLWRGLSLDPHHLPSARIGKPLPDFALPELQNPDSTFSAIN
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
FHNQVVLLNVWASWCEACVEEQVFMLQLAREGVPIYGLNYKDNPEHARAWLSQWGNPYRL
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCEEE
IGQDSEGKVAIDLGVYGAPETFVIDKKGIVRYRHVGIMNQKTWLTDILPLMRNLEKS
ECCCCCCCEEEEEECCCCCCEEEEECCCCEEEHHCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKVGWRVIPIAIFCLLCFFLWRGLSLDPHHLPSARIGKPLPDFALPELQNPDSTFSAIN
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
FHNQVVLLNVWASWCEACVEEQVFMLQLAREGVPIYGLNYKDNPEHARAWLSQWGNPYRL
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCEEE
IGQDSEGKVAIDLGVYGAPETFVIDKKGIVRYRHVGIMNQKTWLTDILPLMRNLEKS
ECCCCCCCEEEEEECCCCCCEEEEECCCCEEEHHCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]