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The map label for this gene is hbpA [H]

Identifier: 148360389

GI number: 148360389

Start: 1153682

End: 1155847

Strand: Direct

Name: hbpA [H]

Synonym: LPC_2328

Alternate gene names: 148360389

Gene position: 1153682-1155847 (Clockwise)

Preceding gene: 148360390

Following gene: 148360388

Centisome position: 32.26

GC content: 37.67

Gene sequence:

>2166_bases
ATGCAATTCATGTTATTTTTAATGCCTTGCTGTGTCAATTTGGCTTATGGCAGTTCTTGGGTATTCAATAATCCTTACCC
AGAGAGCGAGGCCAATGAAAATATTTATTATTCTTCTTTTAATGAACAGCCAAAAACCCTGGATCCGGCACGTTCCTATT
CTTCCAATGAATATCTTTTCATAGCCCAGATCTATGAGCCACTGCTGGAATATGATTACTATAAAAGACCCTATGAATTA
ATCCCATTAACAGCTACCCGCTTACCACAGATTCGATATTTGGATGCCCAGGGAAATCCTGTTTCGGCAGGAGATAACAC
AAAGCCAGCATACAGTGTCTATACCATTCAGATAAAAAAAGGAATTTTATATCAACCTCATCCTGCTTTGGCTCAAAAGA
AAGATGGCTCTTATCGATATCATCACTTACCAGAAGATTATTTGGAAGAGCATGATATTAGCAAGTTGTCAGATTTTAAA
TACACCGGTACAAGGGAGCTGATCATTGATGATTACATTTATCAAATTAAAAGATTGGCAAACCCTGCTGTGAGTTCTCC
GATATATGGATTGATGAGCTATTACATTCTGGGCTTCAAGGAGTATGGAGATAGTCTTCCTAAAGGATTGGCCAATAAAA
ATTCTTTTATTGATTTACGTAAGTATCCTTTGAAGGGGGTTAAAAAATTAGATGATTACACCTTTGAGATTACATTAAAG
GGACAATATACACAATTTTTGTTTTGGTTAGCCATGCCCTTTTTTGCTCCGGTTCCTTGGGAAGCGGACTTATTTTATTC
CCAAAAAGATATGGATGATAAGAACTTATCTTTTGGCTGGTATCCTATAGGTACAGGGCCTTTTATGCTGACTGAAAATA
ATCCCAATAGAAGCATGATATTGGAGAAAAATCCTAATTTCAGAGAAGTGTATTTTCCTGTCAATGGTTCAGATGCCGAT
AGACGGGCAGGTTATTTAACCAATCAGGGAAGGCGCTTGCCCTTAATTGATAAAGCCGTTTATACCCTTGAAAAGGAATC
CATACCTCGATGGAATAAATTCTTGCAAGGCTACTATGATATGTCGGGGATAAGTGCTGACAGTTTTGATCAGGCTATTC
ATATTAATCGCTTTGGAGAACCTATCCTTAGCCAGGAAATGAAAGATAAAAAAATATATTTAAGACAAACCCTGGAACCG
TCTATCTATTATACTGGCTTTAATATGCTTGACAGCGTTGTTGGGGGCAATAGCAAAAGAGCACGAAAATTACGCCAGGC
AATTTCTATTGCGGTGAATTTTGATGAAAATATTGCCATATTTTTTAATGGCCGAGGTATTCCGGCGCAAGGCCCTATTC
CACCTGGTATCTTTGGGTACAAGGAAGGAAAAGAGGGTATTAATCCCTATGTTTATCAATGGGTGAATAATGCCAGGAAA
CGAAAATCCTTAAAGGATGCGCAGAAGTTAATGGTTGAGGCAGGATATCCGGGAGGGATAGATCCGAAAACCGGGAAACA
CCTGATTCTTCATTATGATGTTATGACGACAGGTGGACCTGATGATAAAGCAAGGCTTGACTGGATGCGAAAGCAATTTG
CAAATATAGGGATAGATTTGAATATTAGGGCGACCCTTTACAATCGTTTCCAGGAAAAGATGCGGATAGGTCATGCTCAA
ATATTTAGTTGGGGCTGGAATGCCGATTATCCTGATCCCGAAAATTTTTTATTTTTGCTTTATGGAAAAAATGGAAAAGT
GAAGTATGGTGGTGAAAATGCATCAAATTATGAAAATCCTGAATTTGATAGATTGTTTAATTTGATGAAAAATCGCCCTA
ACGATCTACAAAGACAAAAACTGATTGATAAGATGTTAGCGATGGTCCGGTATGATGCTCCATGGGTATGGGGTATGCAT
TCTGAAGACTTTATTTTATCGCAAGATTGGGTATCTAATATAAAATCCAATACGATTTCTCTCAATACTCTAAAATATGT
TTCTGTTAATGTACCTGAACGTAACCAACTGCGAAGATCCTGGAATCAACCGGTATTTTGGCCTTTAGGTGTGCTGTTTG
GCCTATTGATTGTTTTGGTAATCCCTTTATTGATTACTTATTTAAAGAAAGAAAAACAGCCGGCAGAAAGAGTAAAATTA
AAATGA

Upstream 100 bases:

>100_bases
TTGGTTTATGATGGGTATCAATGAATCGGGTGAAGTAGGTATTTAAACCTGTAATAATGACTGATTGGCACGAGGGAAGT
AAGTGCGGCGATATTTGTTA

Downstream 100 bases:

>100_bases
TTAAATACATACTCCGCAGAATTTTATATGCGATTCCAATTTTGTTTGGTATTAATCTTATTACTTTTGCATTGTTTTTC
ATGGTTAATTCTCCCGATGA

Product: extracellular solute-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 721; Mature: 721

Protein sequence:

>721_residues
MQFMLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQIYEPLLEYDYYKRPYEL
IPLTATRLPQIRYLDAQGNPVSAGDNTKPAYSVYTIQIKKGILYQPHPALAQKKDGSYRYHHLPEDYLEEHDISKLSDFK
YTGTRELIIDDYIYQIKRLANPAVSSPIYGLMSYYILGFKEYGDSLPKGLANKNSFIDLRKYPLKGVKKLDDYTFEITLK
GQYTQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENNPNRSMILEKNPNFREVYFPVNGSDAD
RRAGYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSGISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEP
SIYYTGFNMLDSVVGGNSKRARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARK
RKSLKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIRATLYNRFQEKMRIGHAQ
IFSWGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFDRLFNLMKNRPNDLQRQKLIDKMLAMVRYDAPWVWGMH
SEDFILSQDWVSNIKSNTISLNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIVLVIPLLITYLKKEKQPAERVKL
K

Sequences:

>Translated_721_residues
MQFMLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQIYEPLLEYDYYKRPYEL
IPLTATRLPQIRYLDAQGNPVSAGDNTKPAYSVYTIQIKKGILYQPHPALAQKKDGSYRYHHLPEDYLEEHDISKLSDFK
YTGTRELIIDDYIYQIKRLANPAVSSPIYGLMSYYILGFKEYGDSLPKGLANKNSFIDLRKYPLKGVKKLDDYTFEITLK
GQYTQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENNPNRSMILEKNPNFREVYFPVNGSDAD
RRAGYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSGISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEP
SIYYTGFNMLDSVVGGNSKRARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARK
RKSLKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIRATLYNRFQEKMRIGHAQ
IFSWGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFDRLFNLMKNRPNDLQRQKLIDKMLAMVRYDAPWVWGMH
SEDFILSQDWVSNIKSNTISLNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIVLVIPLLITYLKKEKQPAERVKL
K
>Mature_721_residues
MQFMLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQIYEPLLEYDYYKRPYEL
IPLTATRLPQIRYLDAQGNPVSAGDNTKPAYSVYTIQIKKGILYQPHPALAQKKDGSYRYHHLPEDYLEEHDISKLSDFK
YTGTRELIIDDYIYQIKRLANPAVSSPIYGLMSYYILGFKEYGDSLPKGLANKNSFIDLRKYPLKGVKKLDDYTFEITLK
GQYTQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENNPNRSMILEKNPNFREVYFPVNGSDAD
RRAGYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSGISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEP
SIYYTGFNMLDSVVGGNSKRARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARK
RKSLKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIRATLYNRFQEKMRIGHAQ
IFSWGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFDRLFNLMKNRPNDLQRQKLIDKMLAMVRYDAPWVWGMH
SEDFILSQDWVSNIKSNTISLNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIVLVIPLLITYLKKEKQPAERVKL
K

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=531, Percent_Identity=23.9171374764595, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 83679; Mature: 83679

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFMLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLF
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHCCCCCCEEE
IAQIYEPLLEYDYYKRPYELIPLTATRLPQIRYLDAQGNPVSAGDNTKPAYSVYTIQIKK
EHHHHHHHHHHHHHCCCCEEEEECHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEEC
GILYQPHPALAQKKDGSYRYHHLPEDYLEEHDISKLSDFKYTGTRELIIDDYIYQIKRLA
CCEECCCCHHHCCCCCCEEECCCCHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHC
NPAVSSPIYGLMSYYILGFKEYGDSLPKGLANKNSFIDLRKYPLKGVKKLDDYTFEITLK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHCCHHHHHHCCCEEEEEEEC
GQYTQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENNPNRSMI
CCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCEEEECCCCCCEEE
LEKNPNFREVYFPVNGSDADRRAGYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYD
EECCCCCEEEEEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHC
MSGISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEPSIYYTGFNMLDSVVGGNSKR
CCCCCCCCHHCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCHHH
ARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARK
HHHHHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RKSLKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDL
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEE
NIRATLYNRFQEKMRIGHAQIFSWGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENP
EEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCC
EFDRLFNLMKNRPNDLQRQKLIDKMLAMVRYDAPWVWGMHSEDFILSQDWVSNIKSNTIS
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECHHHHHHHCCCEEE
LNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIVLVIPLLITYLKKEKQPAERVKL
EEEEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
K
C
>Mature Secondary Structure
MQFMLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLF
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHCCCCCCEEE
IAQIYEPLLEYDYYKRPYELIPLTATRLPQIRYLDAQGNPVSAGDNTKPAYSVYTIQIKK
EHHHHHHHHHHHHHCCCCEEEEECHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEEC
GILYQPHPALAQKKDGSYRYHHLPEDYLEEHDISKLSDFKYTGTRELIIDDYIYQIKRLA
CCEECCCCHHHCCCCCCEEECCCCHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHC
NPAVSSPIYGLMSYYILGFKEYGDSLPKGLANKNSFIDLRKYPLKGVKKLDDYTFEITLK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHCCHHHHHHCCCEEEEEEEC
GQYTQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENNPNRSMI
CCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCEEEECCCCCCEEE
LEKNPNFREVYFPVNGSDADRRAGYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYD
EECCCCCEEEEEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHC
MSGISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEPSIYYTGFNMLDSVVGGNSKR
CCCCCCCCHHCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCHHH
ARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARK
HHHHHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RKSLKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDL
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEE
NIRATLYNRFQEKMRIGHAQIFSWGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENP
EEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCC
EFDRLFNLMKNRPNDLQRQKLIDKMLAMVRYDAPWVWGMHSEDFILSQDWVSNIKSNTIS
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECHHHHHHHCCCEEE
LNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIVLVIPLLITYLKKEKQPAERVKL
EEEEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]