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The map label for this gene is ttdR [H]

Identifier: 148360176

GI number: 148360176

Start: 2858854

End: 2859762

Strand: Direct

Name: ttdR [H]

Synonym: LPC_2107

Alternate gene names: 148360176

Gene position: 2858854-2859762 (Clockwise)

Preceding gene: 148360177

Following gene: 148360174

Centisome position: 79.94

GC content: 36.08

Gene sequence:

>909_bases
ATGAATATTTTATCCTGTTTGAAAGGCTTTATTACAACCGTTGATTGCAAAAGCTTTTCAAAGGCAGCGCAGAAATTGTA
CATATCCCCCTCTAAATTGAGCAAACAAATAACCTGGCTGGAGGAGGAATTAAAAGTTACCTTATTGATACGCTCTACGA
CACGATTAACTGTAACTGATTCAGGTCACAGGTTGTATGAAAAGGCATTGCAGCTTTTCGAGCAATTAGAGGCAGTCAAA
GTCATTGCAACACCTGATCAGCTCGAATTAAATGGCGTAATCAGGCTCTATCTTACTGTCACTCCGGCAATTCCCTATTT
AACCAAATTAAGTATTCAATTTATGCGACAATACCCCAAGATTGAAGTAGATATTATTGTCGGTTCGGATACAAAAGAGC
TTTACTCCTCTACCTTTGATCTGGCTATTTCATTTGATGATGTCAAACATTCAAAACTGGTTTGCAAAAGATTATTTTCA
ATTCAAAGAAAGGTCTTTGCCTCACCTGGTTATATTACTCAACATGGACTTCCTCAGACACTCGACGAATTACCAAAGCA
TAATTGTTTGATTAATACTCTCTATGGCCTGCAAAATAAATGGGTTTTTAACAAAAAAATCATTCATGTCTCGGGAAATT
TTAAAAGCAACAATGCTGGTGTCTTAAAACAGGCTGCAGTAGCAGACGTGGGGATTTTGTGGGCACCTTATTTTTCAGTT
TATGAAGAAATAAAAAATGAAGCATTAATTCCAGTATTGCCCAATGAATCTTCACCAGATATCAACCTTTATGCAATTTG
CCCCAAGCCCACTGTAGATGAACAAAAAATTAATTTACTTTTGAACTTTTTTTGTGAAAAGGCCTTGTCAGAAAACATTG
CGACATCCTTTATTGATGGAAATAATTAA

Upstream 100 bases:

>100_bases
CTAATAGCGTTGGTCTATGTCAGTAGGTATGCGGTTGATTTACAAAACTGGTATATAGGTCTATACCATTTAAAAAGAGC
TCGATTAAGAAAATTTTAAG

Downstream 100 bases:

>100_bases
AGATGGATTAGAACTTTTGACTTTGATACTCAGAAAATACACAAGAATGATTGTATTACCCTAAAACTTCAGCAGACGCA
TGGAATTTAGGGTTGTGTGA

Product: LysR family transporter transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MNILSCLKGFITTVDCKSFSKAAQKLYISPSKLSKQITWLEEELKVTLLIRSTTRLTVTDSGHRLYEKALQLFEQLEAVK
VIATPDQLELNGVIRLYLTVTPAIPYLTKLSIQFMRQYPKIEVDIIVGSDTKELYSSTFDLAISFDDVKHSKLVCKRLFS
IQRKVFASPGYITQHGLPQTLDELPKHNCLINTLYGLQNKWVFNKKIIHVSGNFKSNNAGVLKQAAVADVGILWAPYFSV
YEEIKNEALIPVLPNESSPDINLYAICPKPTVDEQKINLLLNFFCEKALSENIATSFIDGNN

Sequences:

>Translated_302_residues
MNILSCLKGFITTVDCKSFSKAAQKLYISPSKLSKQITWLEEELKVTLLIRSTTRLTVTDSGHRLYEKALQLFEQLEAVK
VIATPDQLELNGVIRLYLTVTPAIPYLTKLSIQFMRQYPKIEVDIIVGSDTKELYSSTFDLAISFDDVKHSKLVCKRLFS
IQRKVFASPGYITQHGLPQTLDELPKHNCLINTLYGLQNKWVFNKKIIHVSGNFKSNNAGVLKQAAVADVGILWAPYFSV
YEEIKNEALIPVLPNESSPDINLYAICPKPTVDEQKINLLLNFFCEKALSENIATSFIDGNN
>Mature_302_residues
MNILSCLKGFITTVDCKSFSKAAQKLYISPSKLSKQITWLEEELKVTLLIRSTTRLTVTDSGHRLYEKALQLFEQLEAVK
VIATPDQLELNGVIRLYLTVTPAIPYLTKLSIQFMRQYPKIEVDIIVGSDTKELYSSTFDLAISFDDVKHSKLVCKRLFS
IQRKVFASPGYITQHGLPQTLDELPKHNCLINTLYGLQNKWVFNKKIIHVSGNFKSNNAGVLKQAAVADVGILWAPYFSV
YEEIKNEALIPVLPNESSPDINLYAICPKPTVDEQKINLLLNFFCEKALSENIATSFIDGNN

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=293, Percent_Identity=27.3037542662116, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786401, Length=285, Percent_Identity=26.6666666666667, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=26.6891891891892, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1789639, Length=300, Percent_Identity=27, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693193, Length=294, Percent_Identity=24.4897959183673, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788706, Length=178, Percent_Identity=32.0224719101124, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787128, Length=269, Percent_Identity=24.5353159851301, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787589, Length=270, Percent_Identity=22.962962962963, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1790208, Length=144, Percent_Identity=29.1666666666667, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788481, Length=187, Percent_Identity=29.4117647058824, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34066; Mature: 34066

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILSCLKGFITTVDCKSFSKAAQKLYISPSKLSKQITWLEEELKVTLLIRSTTRLTVTD
CCHHHHHHHHHEECCHHHHHHHHHHEECCHHHHHHHHHHHHHCEEEEEEEECCEEEEEEC
SGHRLYEKALQLFEQLEAVKVIATPDQLELNGVIRLYLTVTPAIPYLTKLSIQFMRQYPK
CCHHHHHHHHHHHHHHHHEEEEECCCCEEECCEEEEEEEECCCHHHHHHHHHHHHHHCCC
IEVDIIVGSDTKELYSSTFDLAISFDDVKHSKLVCKRLFSIQRKVFASPGYITQHGLPQT
EEEEEEECCCHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LDELPKHNCLINTLYGLQNKWVFNKKIIHVSGNFKSNNAGVLKQAAVADVGILWAPYFSV
HHHCCCCCEEHHHHHCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YEEIKNEALIPVLPNESSPDINLYAICPKPTVDEQKINLLLNFFCEKALSENIATSFIDG
HHHHHCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
NN
CC
>Mature Secondary Structure
MNILSCLKGFITTVDCKSFSKAAQKLYISPSKLSKQITWLEEELKVTLLIRSTTRLTVTD
CCHHHHHHHHHEECCHHHHHHHHHHEECCHHHHHHHHHHHHHCEEEEEEEECCEEEEEEC
SGHRLYEKALQLFEQLEAVKVIATPDQLELNGVIRLYLTVTPAIPYLTKLSIQFMRQYPK
CCHHHHHHHHHHHHHHHHEEEEECCCCEEECCEEEEEEEECCCHHHHHHHHHHHHHHCCC
IEVDIIVGSDTKELYSSTFDLAISFDDVKHSKLVCKRLFSIQRKVFASPGYITQHGLPQT
EEEEEEECCCHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LDELPKHNCLINTLYGLQNKWVFNKKIIHVSGNFKSNNAGVLKQAAVADVGILWAPYFSV
HHHCCCCCEEHHHHHCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YEEIKNEALIPVLPNESSPDINLYAICPKPTVDEQKINLLLNFFCEKALSENIATSFIDG
HHHHHCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
NN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]