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The map label for this gene is mdcB [H]

Identifier: 148360118

GI number: 148360118

Start: 2924739

End: 2925935

Strand: Direct

Name: mdcB [H]

Synonym: LPC_2049

Alternate gene names: 148360118

Gene position: 2924739-2925935 (Clockwise)

Preceding gene: 148360119

Following gene: 148360117

Centisome position: 81.78

GC content: 41.6

Gene sequence:

>1197_bases
ATGGATAAATATCATTACACATTCAGTTTGCCCAAAAAAATCCAGATATCTCCAATGATTAAAGTTGGAGTGGCCGGTTC
AGGTAATTTGGAAGTGATTATTAAACCAAACTCTGACTTTGATAAAACCGAGATTATTGTAAATACTGTAATCTCTGGTT
TCCGAAATACCTGGGATGCTGTAATCGAACGCTTTGTTGAAGACTATCCCTATAGCGGGCTATCCATTACTCTTAACGAT
GCGGGCGCTACCCCTCCCGTCGTTTCCTTACGCCTGCGTCAAGCAATGGAAACCTACCAAACAGGATATCCTAAAAAGGA
TAGCTATACGGAAGCGAACGCTCGCAATAGAATTTATTCATTAGTTGATGAAGCAAGTTTTACAGAGTTTTTACTTGATA
AAGAGACACCAAGTCCAACCTTGCCTCAGTTAAACATGCAAGTGGAAACTGATGATGGGGTCATCATTGGCACCGCCAAA
ATGGATGGAATTGATATTGCTATCGCATCGCAACAAAAAGATTTCATTGGCGGGTCAGTAGGAGAGATACATGGTGCCAA
AATCAATGGTCTAATCAAGTATGCAATTAAAAATCAACTTCCTGCAATCATTTTTTTGATTGACAGTGGTGGAGTCCGTT
TGCAAGAGGCGAATGTAGGTGAGATTGAAATTTCTGAAATCATTCGCTCAATCCTGGATGCTCGCTCAGCCGGCATTAAA
ACCATAGGCGTTATTTGTGGCAATAACGGGGCTTTTGGTGGCATGGGGATCATAAGTGGCACCCTTGATTATCTTATCGT
TAATCAAGGAGCACGTATTGGGGTATCAGGAGCGGAAGTAATTCAGGCAGTAAAAGGAGTTGAAGTATTTGATAGCAGTA
ATCGTCCATTAGTCTGGCGAGTCTATGGTGGTAGAACCCGCTTTCTTAAAGCCGATGTTCAAGGATACACCACCAATAAA
ACCATGGATATTCGTCAGGCGATAAAAACCGCCCTTAAAACGCTCCCCACTGCCCCATCCCTTAATCTGAATTCTATTCT
GGCAGAGCATGAACAACTGCAAAAACGCATTGCCTCAGCCAAAAATTGCCGTGAGGAAGGTGAGTGGTTAAAAAACAACC
GAACTGAATTATATCAGCAAGACATATTCAATGTTTCTGACCAGCAATTCCTAGCATTGACTAATAAAGGGAAATAA

Upstream 100 bases:

>100_bases
ATCGAGATCTACTCGCTGCCAAAAACATCCATGATTTAGTGGAAATTTCGCATGGACTTTATTGTCCTCCTAACAAATTC
AGGAATTGGTAGACCTATTT

Downstream 100 bases:

>100_bases
ATGATGCCCAATGAAAAAATTACTTTAAAACAATTAATTGATCATTGCTTCGACACAACAAAAACAACAATTAAACAGCA
AATTGTTTTTGGATCCGGGA

Product: acetyl CoA carboxylase carboxyltransferase subunit beta

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDKYHYTFSLPKKIQISPMIKVGVAGSGNLEVIIKPNSDFDKTEIIVNTVISGFRNTWDAVIERFVEDYPYSGLSITLND
AGATPPVVSLRLRQAMETYQTGYPKKDSYTEANARNRIYSLVDEASFTEFLLDKETPSPTLPQLNMQVETDDGVIIGTAK
MDGIDIAIASQQKDFIGGSVGEIHGAKINGLIKYAIKNQLPAIIFLIDSGGVRLQEANVGEIEISEIIRSILDARSAGIK
TIGVICGNNGAFGGMGIISGTLDYLIVNQGARIGVSGAEVIQAVKGVEVFDSSNRPLVWRVYGGRTRFLKADVQGYTTNK
TMDIRQAIKTALKTLPTAPSLNLNSILAEHEQLQKRIASAKNCREEGEWLKNNRTELYQQDIFNVSDQQFLALTNKGK

Sequences:

>Translated_398_residues
MDKYHYTFSLPKKIQISPMIKVGVAGSGNLEVIIKPNSDFDKTEIIVNTVISGFRNTWDAVIERFVEDYPYSGLSITLND
AGATPPVVSLRLRQAMETYQTGYPKKDSYTEANARNRIYSLVDEASFTEFLLDKETPSPTLPQLNMQVETDDGVIIGTAK
MDGIDIAIASQQKDFIGGSVGEIHGAKINGLIKYAIKNQLPAIIFLIDSGGVRLQEANVGEIEISEIIRSILDARSAGIK
TIGVICGNNGAFGGMGIISGTLDYLIVNQGARIGVSGAEVIQAVKGVEVFDSSNRPLVWRVYGGRTRFLKADVQGYTTNK
TMDIRQAIKTALKTLPTAPSLNLNSILAEHEQLQKRIASAKNCREEGEWLKNNRTELYQQDIFNVSDQQFLALTNKGK
>Mature_398_residues
MDKYHYTFSLPKKIQISPMIKVGVAGSGNLEVIIKPNSDFDKTEIIVNTVISGFRNTWDAVIERFVEDYPYSGLSITLND
AGATPPVVSLRLRQAMETYQTGYPKKDSYTEANARNRIYSLVDEASFTEFLLDKETPSPTLPQLNMQVETDDGVIIGTAK
MDGIDIAIASQQKDFIGGSVGEIHGAKINGLIKYAIKNQLPAIIFLIDSGGVRLQEANVGEIEISEIIRSILDARSAGIK
TIGVICGNNGAFGGMGIISGTLDYLIVNQGARIGVSGAEVIQAVKGVEVFDSSNRPLVWRVYGGRTRFLKADVQGYTTNK
TMDIRQAIKTALKTLPTAPSLNLNSILAEHEQLQKRIASAKNCREEGEWLKNNRTELYQQDIFNVSDQQFLALTNKGK

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788655, Length=202, Percent_Identity=25.7425742574257, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 43658; Mature: 43658

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKYHYTFSLPKKIQISPMIKVGVAGSGNLEVIIKPNSDFDKTEIIVNTVISGFRNTWDA
CCCEEEEEECCCEEEECCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
VIERFVEDYPYSGLSITLNDAGATPPVVSLRLRQAMETYQTGYPKKDSYTEANARNRIYS
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LVDEASFTEFLLDKETPSPTLPQLNMQVETDDGVIIGTAKMDGIDIAIASQQKDFIGGSV
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEEECCCCEEEEEECCCCHHCCCCC
GEIHGAKINGLIKYAIKNQLPAIIFLIDSGGVRLQEANVGEIEISEIIRSILDARSAGIK
CCCCCCCHHHHHHEEHHCCCCEEEEEECCCCEEEEECCCCCEEHHHHHHHHHHHHCCCCE
TIGVICGNNGAFGGMGIISGTLDYLIVNQGARIGVSGAEVIQAVKGVEVFDSSNRPLVWR
EEEEEECCCCCCCCCHHHHCCEEEEEEECCCEECCCHHHHHHHHCCCCEECCCCCCEEEE
VYGGRTRFLKADVQGYTTNKTMDIRQAIKTALKTLPTAPSLNLNSILAEHEQLQKRIASA
EECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
KNCREEGEWLKNNRTELYQQDIFNVSDQQFLALTNKGK
HHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCC
>Mature Secondary Structure
MDKYHYTFSLPKKIQISPMIKVGVAGSGNLEVIIKPNSDFDKTEIIVNTVISGFRNTWDA
CCCEEEEEECCCEEEECCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
VIERFVEDYPYSGLSITLNDAGATPPVVSLRLRQAMETYQTGYPKKDSYTEANARNRIYS
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LVDEASFTEFLLDKETPSPTLPQLNMQVETDDGVIIGTAKMDGIDIAIASQQKDFIGGSV
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEEECCCCEEEEEECCCCHHCCCCC
GEIHGAKINGLIKYAIKNQLPAIIFLIDSGGVRLQEANVGEIEISEIIRSILDARSAGIK
CCCCCCCHHHHHHEEHHCCCCEEEEEECCCCEEEEECCCCCEEHHHHHHHHHHHHCCCCE
TIGVICGNNGAFGGMGIISGTLDYLIVNQGARIGVSGAEVIQAVKGVEVFDSSNRPLVWR
EEEEEECCCCCCCCCHHHHCCEEEEEEECCCEECCCHHHHHHHHCCCCEECCCCCCEEEE
VYGGRTRFLKADVQGYTTNKTMDIRQAIKTALKTLPTAPSLNLNSILAEHEQLQKRIASA
EECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
KNCREEGEWLKNNRTELYQQDIFNVSDQQFLALTNKGK
HHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]