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The map label for this gene is hypD [H]

Identifier: 148360075

GI number: 148360075

Start: 2963346

End: 2964452

Strand: Reverse

Name: hypD [H]

Synonym: LPC_2006

Alternate gene names: 148360075

Gene position: 2964452-2963346 (Counterclockwise)

Preceding gene: 148360074

Following gene: 148360076

Centisome position: 82.89

GC content: 41.73

Gene sequence:

>1107_bases
GTGAAATACATAGAAGAGTTTCGTAACGGTGCTTACGCACAAGCCATTATCAATGAAATTATCGCAACAGCAGATCCACA
AAGACATTATCAGTTTATGGAGTTTTGTGGAGGCCATACTCATGCTATTCATCGTTATGGGATTCCAAGTTTGCTTCCCA
ACAATGTTGAAATGATTCATGGCCCCGGTTGCCCTGTTTGCGTTTTGCCTATAGCGAGAATTGATAAGGCTATTGCGCTT
GCCTCAATGCAGCAAGTGATTCTGTGCAGCTATGCTGACATGCTGCGAGTCCCAGGAAGTGGACAAAAAAGTTTATTAAC
CGCCAAAGCATGCGGCGCTGATGTCAGGATGGTCTATTCTGCGAATGATACATTAAAAATCGCTCAGGAAAACCCCAATA
AAGACATTGTGTTTTTTGCTATAGGCTTTGAAACAACAATACCTCCCACTGCTTTTGTCATTAAGCAAGCTAAAAAATTA
AACATCACTAATTTCAGTGTATTTTGTAACCATGTGTTAACTCCCATTGCTATGGATAGTTTGCTACAGGCCAATGAAGT
TGCCCTGGACGGCTTTGTTGGCCCAGCCCATGTCAGTATCGTGATTGGGAGTTTTCCTTATGAGCAAGTTTGTAAAAAAT
ACCAAAAACCTATCGTGATATCAGGGTTTGAGCCGTTGGATGTGTTGCATTCTATTCTGATGTTAATTCAACAATTGAAT
GAGGGGCGTTGTGATGTGGAAATTCAATACACTCGTGCAGTGAATCGTAAGGGTAATCTTTTGTCACAACACATAATGGC
CGAAGTCCTGGAAATACGCGATCGTTTTGAATGGCGTGGTTTGGGTTTTATTCCATCCAGCGCGTTAAAGATCAAAGAGT
CTTTTTCTGAGTTTGATGCTGAACAGCGTTTCGAATTACCTGAGAGTGCAGCGCAGGAACATAAGCAATGTCTTTGTGGT
GAGGTATTAAGGGGAGTAAAAAAACCAACTGATTGCAAATTATTTGCCAAGGCTTGCTTGCCAGAAAATCCTTTAGGATC
CTGTATGGTTTCATCGGAGGGAGCTTGTGCAGCAGTTTATGCTTATGGACGGGTTAATGCTTTATGA

Upstream 100 bases:

>100_bases
ACGTCATTATTCATGCAGGATTCGCCTTAACAAAACTGGATGAAAGAGAGGCAAACAAAACATTGAGTTTGTTTGCCCAT
ATGCTAAAGGATGGCTTGAA

Downstream 100 bases:

>100_bases
ATGAAATCCTGATAACTAAAAAATTAACGGGGCCAAAGCTGAATTTTAAAGAAGGTACTATCAATTTGACCCATGGCAGT
GGTGGACGTGCTATGGCTCA

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKYIEEFRNGAYAQAIINEIIATADPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIHGPGCPVCVLPIARIDKAIAL
ASMQQVILCSYADMLRVPGSGQKSLLTAKACGADVRMVYSANDTLKIAQENPNKDIVFFAIGFETTIPPTAFVIKQAKKL
NITNFSVFCNHVLTPIAMDSLLQANEVALDGFVGPAHVSIVIGSFPYEQVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
EGRCDVEIQYTRAVNRKGNLLSQHIMAEVLEIRDRFEWRGLGFIPSSALKIKESFSEFDAEQRFELPESAAQEHKQCLCG
EVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVYAYGRVNAL

Sequences:

>Translated_368_residues
MKYIEEFRNGAYAQAIINEIIATADPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIHGPGCPVCVLPIARIDKAIAL
ASMQQVILCSYADMLRVPGSGQKSLLTAKACGADVRMVYSANDTLKIAQENPNKDIVFFAIGFETTIPPTAFVIKQAKKL
NITNFSVFCNHVLTPIAMDSLLQANEVALDGFVGPAHVSIVIGSFPYEQVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
EGRCDVEIQYTRAVNRKGNLLSQHIMAEVLEIRDRFEWRGLGFIPSSALKIKESFSEFDAEQRFELPESAAQEHKQCLCG
EVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVYAYGRVNAL
>Mature_368_residues
MKYIEEFRNGAYAQAIINEIIATADPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIHGPGCPVCVLPIARIDKAIAL
ASMQQVILCSYADMLRVPGSGQKSLLTAKACGADVRMVYSANDTLKIAQENPNKDIVFFAIGFETTIPPTAFVIKQAKKL
NITNFSVFCNHVLTPIAMDSLLQANEVALDGFVGPAHVSIVIGSFPYEQVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
EGRCDVEIQYTRAVNRKGNLLSQHIMAEVLEIRDRFEWRGLGFIPSSALKIKESFSEFDAEQRFELPESAAQEHKQCLCG
EVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVYAYGRVNAL

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=367, Percent_Identity=46.0490463215259, Blast_Score=345, Evalue=2e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 40644; Mature: 40644

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYIEEFRNGAYAQAIINEIIATADPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIH
CCHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEE
GPGCPVCVLPIARIDKAIALASMQQVILCSYADMLRVPGSGQKSLLTAKACGADVRMVYS
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEHHHCCCCEEEEEE
ANDTLKIAQENPNKDIVFFAIGFETTIPPTAFVIKQAKKLNITNFSVFCNHVLTPIAMDS
CCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLQANEVALDGFVGPAHVSIVIGSFPYEQVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
HHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHC
EGRCDVEIQYTRAVNRKGNLLSQHIMAEVLEIRDRFEWRGLGFIPSSALKIKESFSEFDA
CCCCCEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
EQRFELPESAAQEHKQCLCGEVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVY
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEECCCCCEEEEE
AYGRVNAL
ECCCCCCC
>Mature Secondary Structure
MKYIEEFRNGAYAQAIINEIIATADPQRHYQFMEFCGGHTHAIHRYGIPSLLPNNVEMIH
CCHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEE
GPGCPVCVLPIARIDKAIALASMQQVILCSYADMLRVPGSGQKSLLTAKACGADVRMVYS
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEHHHCCCCEEEEEE
ANDTLKIAQENPNKDIVFFAIGFETTIPPTAFVIKQAKKLNITNFSVFCNHVLTPIAMDS
CCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLQANEVALDGFVGPAHVSIVIGSFPYEQVCKKYQKPIVISGFEPLDVLHSILMLIQQLN
HHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHC
EGRCDVEIQYTRAVNRKGNLLSQHIMAEVLEIRDRFEWRGLGFIPSSALKIKESFSEFDA
CCCCCEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
EQRFELPESAAQEHKQCLCGEVLRGVKKPTDCKLFAKACLPENPLGSCMVSSEGACAAVY
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEECCCCCEEEEE
AYGRVNAL
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8352644; 12948488 [H]