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The map label for this gene is aspB [H]

Identifier: 148360006

GI number: 148360006

Start: 3037303

End: 3038469

Strand: Direct

Name: aspB [H]

Synonym: LPC_1936

Alternate gene names: 148360006

Gene position: 3037303-3038469 (Clockwise)

Preceding gene: 148360007

Following gene: 148360005

Centisome position: 84.92

GC content: 43.62

Gene sequence:

>1167_bases
ATGAACCATTATGAAAAAATGAGCTTGTTAAAAGATTCCGCAACAGTTGCCATCAATTCTCTAGCCCAACAAAAAATAAA
CGCGGGAATCAAAATTCATAACCTCAGTGCTGGAGAACCCAAACTGCCACCCCATCCCTCCATAATAAATGCCGTCACAC
AAGCTATGGAACAAGGACATACCCTTTATCCTCCAATAATGGGAATTCCTGAACTACGTCATATGGGCTGTGAATGGATG
TATAGATCCTATGATTGCTCATTCCAAAATGAGCAATGCCTGGTTGTGAATGGCGGAAAACTCGGCATTTATTTACTCAT
GCAATTATTACTGCAGCCTAACGACGAAGTCATTATTCCTTCTCCCTACTGGGTTTCCTATCCAGCCATGGTTAGTCTCT
TTGGCGGCACCCCCGTGTCAGTTGAAACGACAGAAGCCGAAGAATGGAAATTAACGCCAAAGGCATTGCAAAAAGCGTGT
ACCACAAAAAGTAAAATACTCATTCTGAATAATGCCACCAATCCCACCGGAGCTCTGTATACCCAGTCCGAGCTGATTCA
CTTATTGCAAATTGCCAAGAAGCATAATCTTTTAGTGATCTCCGATGAAGTTTACAGCGAACTGACCTATGATGGGCATC
ATTACGTATCCTGTGGTTCTTTACCCCAATTTCGGGAGCGTGTCATCATCATTCAAAGCTGTTCAAAAAACTTTTCCATG
ACCGGGTGGCGAGTGGGTTTTATTTTTGCCCCGGAAATATTCATCAAACCTTTAAGCGCCCTGGTCAGTCAAAGCACTAG
TGGAGTGACCACCCTTAGCCAATGGGCCGCTGTAGCTGCGCTGCAAGAAGTAAATCAAGTCAATATCTGGGTTCAACAAA
ACATGGAAAAAAGAAGAAATTGCCTCCTCCGCGCCTTGCATGACTATCTGGGATTGACTATAACACCTCCAGTTTCCTCA
CTTTATGTTTTTCTTTCCCTAAAGGATATTGGCTGCAAAAATCAAAATTCCGAGGAGTTTTGTAAACAAGCTTTGGATAA
GGCAAATGTTGCGATGGTGCCGGGAATCGCCTTTGGTAAAGAGGGTTACGTCCGCTTGTCTTTTGGAGGCAATGAAGACG
ATTTAAAATCAGGTATTTATGCCCTGGCGCAATGGCTGCATCGCTGA

Upstream 100 bases:

>100_bases
AATATTATGACTTTTTATCCAGGCAATATCACTTGCAGCAGGATTTCGTGAATCAATTATTCAAGATAATTATCTCAAAC
TCAAAAAAGGCCCAAAAATA

Downstream 100 bases:

>100_bases
TTAAAGTAATTCATTACTTTGCAAGAAGCATTGCTAGACCTCTTGCCTAATCTGATTATTTTCAGGACTTACGAAAAACT
CCAAGGTCAAGGCAAAAAAT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNHYEKMSLLKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGHTLYPPIMGIPELRHMGCEWM
YRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIPSPYWVSYPAMVSLFGGTPVSVETTEAEEWKLTPKALQKAC
TTKSKILILNNATNPTGALYTQSELIHLLQIAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRERVIIIQSCSKNFSM
TGWRVGFIFAPEIFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRNCLLRALHDYLGLTITPPVSS
LYVFLSLKDIGCKNQNSEEFCKQALDKANVAMVPGIAFGKEGYVRLSFGGNEDDLKSGIYALAQWLHR

Sequences:

>Translated_388_residues
MNHYEKMSLLKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGHTLYPPIMGIPELRHMGCEWM
YRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIPSPYWVSYPAMVSLFGGTPVSVETTEAEEWKLTPKALQKAC
TTKSKILILNNATNPTGALYTQSELIHLLQIAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRERVIIIQSCSKNFSM
TGWRVGFIFAPEIFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRNCLLRALHDYLGLTITPPVSS
LYVFLSLKDIGCKNQNSEEFCKQALDKANVAMVPGIAFGKEGYVRLSFGGNEDDLKSGIYALAQWLHR
>Mature_388_residues
MNHYEKMSLLKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGHTLYPPIMGIPELRHMGCEWM
YRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIPSPYWVSYPAMVSLFGGTPVSVETTEAEEWKLTPKALQKAC
TTKSKILILNNATNPTGALYTQSELIHLLQIAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRERVIIIQSCSKNFSM
TGWRVGFIFAPEIFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRNCLLRALHDYLGLTITPPVSS
LYVFLSLKDIGCKNQNSEEFCKQALDKANVAMVPGIAFGKEGYVRLSFGGNEDDLKSGIYALAQWLHR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=403, Percent_Identity=28.5359801488834, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI169881279, Length=403, Percent_Identity=28.5359801488834, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI169881281, Length=303, Percent_Identity=29.3729372937294, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI56713256, Length=327, Percent_Identity=27.5229357798165, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI56713254, Length=395, Percent_Identity=26.3291139240506, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI4507369, Length=366, Percent_Identity=21.5846994535519, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI149944424, Length=361, Percent_Identity=26.0387811634349, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI187936925, Length=324, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI14211921, Length=324, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI7705897, Length=365, Percent_Identity=22.7397260273973, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI33469970, Length=365, Percent_Identity=22.7397260273973, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1788722, Length=375, Percent_Identity=28.5333333333333, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1786816, Length=388, Percent_Identity=25, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788627, Length=280, Percent_Identity=27.1428571428571, Blast_Score=98, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71994476, Length=197, Percent_Identity=35.5329949238579, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=197, Percent_Identity=35.5329949238579, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=372, Percent_Identity=22.5806451612903, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=199, Percent_Identity=30.1507537688442, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71981209, Length=339, Percent_Identity=22.4188790560472, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=288, Percent_Identity=28.8194444444444, Blast_Score=112, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6320317, Length=343, Percent_Identity=22.1574344023324, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28573069, Length=322, Percent_Identity=24.8447204968944, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24646114, Length=322, Percent_Identity=24.8447204968944, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI28573067, Length=322, Percent_Identity=24.8447204968944, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI28573065, Length=322, Percent_Identity=24.8447204968944, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI18859735, Length=351, Percent_Identity=21.0826210826211, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24641770, Length=278, Percent_Identity=22.6618705035971, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641760, Length=278, Percent_Identity=22.6618705035971, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641768, Length=278, Percent_Identity=22.6618705035971, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641766, Length=278, Percent_Identity=22.6618705035971, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641764, Length=278, Percent_Identity=22.6618705035971, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45551451, Length=278, Percent_Identity=22.6618705035971, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43220; Mature: 43220

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHYEKMSLLKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGH
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
TLYPPIMGIPELRHMGCEWMYRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIP
EECCCCCCCHHHHHCCHHHHEECCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEC
SPYWVSYPAMVSLFGGTPVSVETTEAEEWKLTPKALQKACTTKSKILILNNATNPTGALY
CCCCCCCHHHHHCCCCCCCEEEECCCCCEECCHHHHHHHHCCCCEEEEEECCCCCCCCEE
TQSELIHLLQIAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRERVIIIQSCSKNFSM
EHHHHHHHHHHHHHCCEEEEEHHHHHHHCCCCCEEEEECCCHHHHHHEEEEEECCCCCCC
TGWRVGFIFAPEIFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRN
CCEEEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHH
CLLRALHDYLGLTITPPVSSLYVFLSLKDIGCKNQNSEEFCKQALDKANVAMVPGIAFGK
HHHHHHHHHHCEEECCCHHHEEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCEEECC
EGYVRLSFGGNEDDLKSGIYALAQWLHR
CCEEEEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNHYEKMSLLKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGH
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
TLYPPIMGIPELRHMGCEWMYRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIP
EECCCCCCCHHHHHCCHHHHEECCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEC
SPYWVSYPAMVSLFGGTPVSVETTEAEEWKLTPKALQKACTTKSKILILNNATNPTGALY
CCCCCCCHHHHHCCCCCCCEEEECCCCCEECCHHHHHHHHCCCCEEEEEECCCCCCCCEE
TQSELIHLLQIAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRERVIIIQSCSKNFSM
EHHHHHHHHHHHHHCCEEEEEHHHHHHHCCCCCEEEEECCCHHHHHHEEEEEECCCCCCC
TGWRVGFIFAPEIFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRN
CCEEEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHH
CLLRALHDYLGLTITPPVSSLYVFLSLKDIGCKNQNSEEFCKQALDKANVAMVPGIAFGK
HHHHHHHHHHCEEECCCHHHEEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCEEECC
EGYVRLSFGGNEDDLKSGIYALAQWLHR
CCEEEEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]