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The map label for this gene is helB [H]

Identifier: 148359919

GI number: 148359919

Start: 2796512

End: 2797768

Strand: Reverse

Name: helB [H]

Synonym: LPC_1848

Alternate gene names: 148359919

Gene position: 2797768-2796512 (Counterclockwise)

Preceding gene: 148359920

Following gene: 148359918

Centisome position: 78.23

GC content: 39.86

Gene sequence:

>1257_bases
ATGAATCTATTAAAACCAATCGGTTTATCCCTAAAACTTGCTGTGTTCCTGTTAGGAATGAGCTCTTTTTCGCTTTGGGC
GGAAGAAACAACTCATGCTACAGAAGAAAATAATCATCAAGAGACCATGGAAAAAGGACCTCATGGAGGCCGTTTGTTTA
AAGATGGCGATTTGGCCTTAGAGTTTTTAATTTTTGAGCGTGGTATGCCACCTCACTTTAGAGCTTATCTTTATAAAAAT
GGGGAAATGATTTTGCCCCAAAAGGCAAAATTAATCGTAAATCTCACTCGATTTAGTGGAAAAAAAGAGCAGATTACTTT
TATTCCTGTGGAAAATTTTTTGCAAAGCAACCAGATCATTGAAGAACCTCATTCTTTTGATGTAACAATTCAATTAAATA
GTTTTGGAAAGCCATTGAGTTGGCATTACTCCACGTATGAAGGTCGAGTAAAAATTGCTCCTGCTGTTCTTAAAGCAGCG
GGGATAGAAACAGCAGTTGCCCAAGAACAAACGATAAAAACGCAATTAAATGCTGTAGGTAAAATCGTCACCAATCGTGA
TACTTCAGCACCTATTTATGCACGTTATTCGGGAATTATTAAAGCATTGAATAAAAATTTAGGCGATGAAGTGACAAAAG
GGGATGTGTTGGCAACGATTGAAAGTAATGAGAGTTTGCAAAATTACGAAATAAGGTCACCCATAACGGGAACGATAGTA
CAAAAATATGCAACCAATGGTGAGTTTGCTCAAAACACCAAACCTATTTTTGAGGTAGCCAATTTACTTACTGTTTGGGC
TGATTTTACCTTATATCGCAAGGATGCACCTTTAGTGAAGCCAGGTATGGAAGTCATTGTGACTGGGGATGAAGGAAAGC
CCAAATCAGTAAGTACCATTAGCTACATTTCACCTTTAGGGGTTGAGGACAGTCAAACCACATTGGCACGTGCTGTTCTT
AATAATGACACTCGCATCTGGCTTCCTGGTATGTATGTGAATGGTGCCATCGTGATTAAAGAGAAAACAGCCCCAGTTGC
AGTACTTCTTTCGGCACTCCAACAAATGGGTGAACAAGACGTGGTTTTTGTTCAGCAAGGCGATTATTTTGAAGCCACTC
CAGTTAATCTGGGTGAAAAAGACGAGCAGTGGGCAGAAGTGATTTCGGGATTGGATGCGGGGCAGCGCTATGTGAGCAAA
AACAGTTTTTATATGAAAGCAGAAATAGGCAAAGAAGGCGCAAGCCATGACCACTAA

Upstream 100 bases:

>100_bases
ATGAAGAGGAACGACACTATCAACAGGCACATGCAGATTATCATAAAACATTAATTCAACTTACAGGGCTTTTAGGTCTT
CATCCTACCAAGGAGAGTAA

Downstream 100 bases:

>100_bases
GGAATAGTGATGCTTGAAAAAATCATACGTTTTTCTTTAAAACACCGTTGGTTTGTTCTTTTGTTTACATTTATTATCGC
AGTGCTTGGTGTTTACAATT

Product: cation efflux system HelB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MNLLKPIGLSLKLAVFLLGMSSFSLWAEETTHATEENNHQETMEKGPHGGRLFKDGDLALEFLIFERGMPPHFRAYLYKN
GEMILPQKAKLIVNLTRFSGKKEQITFIPVENFLQSNQIIEEPHSFDVTIQLNSFGKPLSWHYSTYEGRVKIAPAVLKAA
GIETAVAQEQTIKTQLNAVGKIVTNRDTSAPIYARYSGIIKALNKNLGDEVTKGDVLATIESNESLQNYEIRSPITGTIV
QKYATNGEFAQNTKPIFEVANLLTVWADFTLYRKDAPLVKPGMEVIVTGDEGKPKSVSTISYISPLGVEDSQTTLARAVL
NNDTRIWLPGMYVNGAIVIKEKTAPVAVLLSALQQMGEQDVVFVQQGDYFEATPVNLGEKDEQWAEVISGLDAGQRYVSK
NSFYMKAEIGKEGASHDH

Sequences:

>Translated_418_residues
MNLLKPIGLSLKLAVFLLGMSSFSLWAEETTHATEENNHQETMEKGPHGGRLFKDGDLALEFLIFERGMPPHFRAYLYKN
GEMILPQKAKLIVNLTRFSGKKEQITFIPVENFLQSNQIIEEPHSFDVTIQLNSFGKPLSWHYSTYEGRVKIAPAVLKAA
GIETAVAQEQTIKTQLNAVGKIVTNRDTSAPIYARYSGIIKALNKNLGDEVTKGDVLATIESNESLQNYEIRSPITGTIV
QKYATNGEFAQNTKPIFEVANLLTVWADFTLYRKDAPLVKPGMEVIVTGDEGKPKSVSTISYISPLGVEDSQTTLARAVL
NNDTRIWLPGMYVNGAIVIKEKTAPVAVLLSALQQMGEQDVVFVQQGDYFEATPVNLGEKDEQWAEVISGLDAGQRYVSK
NSFYMKAEIGKEGASHDH
>Mature_418_residues
MNLLKPIGLSLKLAVFLLGMSSFSLWAEETTHATEENNHQETMEKGPHGGRLFKDGDLALEFLIFERGMPPHFRAYLYKN
GEMILPQKAKLIVNLTRFSGKKEQITFIPVENFLQSNQIIEEPHSFDVTIQLNSFGKPLSWHYSTYEGRVKIAPAVLKAA
GIETAVAQEQTIKTQLNAVGKIVTNRDTSAPIYARYSGIIKALNKNLGDEVTKGDVLATIESNESLQNYEIRSPITGTIV
QKYATNGEFAQNTKPIFEVANLLTVWADFTLYRKDAPLVKPGMEVIVTGDEGKPKSVSTISYISPLGVEDSQTTLARAVL
NNDTRIWLPGMYVNGAIVIKEKTAPVAVLLSALQQMGEQDVVFVQQGDYFEATPVNLGEKDEQWAEVISGLDAGQRYVSK
NSFYMKAEIGKEGASHDH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 46303; Mature: 46303

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLKPIGLSLKLAVFLLGMSSFSLWAEETTHATEENNHQETMEKGPHGGRLFKDGDLAL
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCEEECCCCEE
EFLIFERGMPPHFRAYLYKNGEMILPQKAKLIVNLTRFSGKKEQITFIPVENFLQSNQII
EEEEECCCCCCCEEEEEEECCCEECCCCCEEEEEEECCCCCCCEEEEEEHHHHHCCCCHH
EEPHSFDVTIQLNSFGKPLSWHYSTYEGRVKIAPAVLKAAGIETAVAQEQTIKTQLNAVG
CCCCCEEEEEEECCCCCCEEEEEECCCCEEEECHHHHHHCCCHHHHHHHHHHHHHHHHHH
KIVTNRDTSAPIYARYSGIIKALNKNLGDEVTKGDVLATIESNESLQNYEIRSPITGTIV
HHEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEECCCCHHHHH
QKYATNGEFAQNTKPIFEVANLLTVWADFTLYRKDAPLVKPGMEVIVTGDEGKPKSVSTI
HHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEECCCCCCCCCEEE
SYISPLGVEDSQTTLARAVLNNDTRIWLPGMYVNGAIVIKEKTAPVAVLLSALQQMGEQD
EEECCCCCCCCHHHHHHHHHCCCCEEEECCEEECCEEEEEECCCCHHHHHHHHHHCCCCC
VVFVQQGDYFEATPVNLGEKDEQWAEVISGLDAGQRYVSKNSFYMKAEIGKEGASHDH
EEEEECCCEEEECCCCCCCCHHHHHHHHHCCHHHHHHHCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MNLLKPIGLSLKLAVFLLGMSSFSLWAEETTHATEENNHQETMEKGPHGGRLFKDGDLAL
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCEEECCCCEE
EFLIFERGMPPHFRAYLYKNGEMILPQKAKLIVNLTRFSGKKEQITFIPVENFLQSNQII
EEEEECCCCCCCEEEEEEECCCEECCCCCEEEEEEECCCCCCCEEEEEEHHHHHCCCCHH
EEPHSFDVTIQLNSFGKPLSWHYSTYEGRVKIAPAVLKAAGIETAVAQEQTIKTQLNAVG
CCCCCEEEEEEECCCCCCEEEEEECCCCEEEECHHHHHHCCCHHHHHHHHHHHHHHHHHH
KIVTNRDTSAPIYARYSGIIKALNKNLGDEVTKGDVLATIESNESLQNYEIRSPITGTIV
HHEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEECCCCHHHHH
QKYATNGEFAQNTKPIFEVANLLTVWADFTLYRKDAPLVKPGMEVIVTGDEGKPKSVSTI
HHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEECCCCCCCCCEEE
SYISPLGVEDSQTTLARAVLNNDTRIWLPGMYVNGAIVIKEKTAPVAVLLSALQQMGEQD
EEECCCCCCCCHHHHHHHHHCCCCEEEECCEEECCEEEEEECCCCHHHHHHHHHHCCCCC
VVFVQQGDYFEATPVNLGEKDEQWAEVISGLDAGQRYVSKNSFYMKAEIGKEGASHDH
EEEEECCCEEEECCCCCCCCHHHHHHHHHCCHHHHHHHCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]