BacMap

Definition	Legionella pneumophila str. Corby chromosome, complete genome.
Accession	NC_009494
Length	3,576,470

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The map label for this gene is bdhA [H]

Identifier: 148359855

GI number: 148359855

Start: 2731533

End: 2732315

Strand: Direct

Name: bdhA [H]

Synonym: LPC_1783

Alternate gene names: 148359855

Gene position: 2731533-2732315 (Clockwise)

Preceding gene: 148359853

Following gene: 148359856

Centisome position: 76.38

GC content: 41.89

Gene sequence:

>783_bases
ATGAAACTGAAGAATAAAATCGCTATTGTCACAGGAGCAGCAAGCGGAATTGGTAAAGAAATTGCGCTTGTTTATGCTAA
AGAAGGGGCAAAGGTAGCAATCGCTGATCTGAATCTTGATCAGGCAAGCCATGTAGCAGAGGAAATCAAATCATCAGGCG
GACAAGCAATGGCTGTTGCCATGAATGTAACTGATGAAGCACAAGTCAATCAGGGCGTGGATAAAGTAGCTGATCACTTT
GGAGGAGTTGATGTTTTAGTCAGCAATGCCGGTATTCAAATCATCGAATCAGTAGATAAATTAGCCTTTTCAGACTGGAA
AAGAATGCTTGCCATTCATTTGGATGGTGCCTTTTTAACTACTAAAGCTTGCTTGAAATACATGTATGCCTCAGGCAATG
GCGGCAGTATTATTTATATGGGCTCGGTCCATTCAAAAGAAGCCTCTGTACTCAAAGCACCTTATGTTACTGCCAAACAT
GGTCTATTGGGTTTATGCAAAGTAGTTGCCAAGGAAGGTGGAACTCATAAGGTAAGGGCCAATGTCATTTGCCCGGGCTT
TGTCCGTACTCCTCTCGTTGACAAACAAATTCCAGAGCAAGCAAAAGAATTAGGCATCAGTGAAGAAGATGTCATCAAGA
AAGTGATGCTAAAAGAAACAGTTGACGGGGAATTCACCACAACAGACGATGTAGCACAAACCGCTTTATTTTTTGCATCA
TTTGAATCGAATGCGCTTACAGGACAATCATTGGTAGTCAGTCATGGTTGGTTCATGGAGTAA

Upstream 100 bases:

>100_bases
TAAACAATTCATCAAAGATTTTTGTTAGCAAATAATAAGGCATTATTAAAAATCCATTGCTATAATCAATTCATGGAAAA
CAATGACAAGGATAGTAAAG

Downstream 100 bases:

>100_bases
ACAACCATGACTCGAACTAAAAAATCTGCAAGACAGATTGAGTATCGCCATATTGCATGCAGCTTTCAGGGAGGAGGGGC
TTTGGGTGCCTATCAAGCTG

Product: 3-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKLKNKIAIVTGAASGIGKEIALVYAKEGAKVAIADLNLDQASHVAEEIKSSGGQAMAVAMNVTDEAQVNQGVDKVADHF
GGVDVLVSNAGIQIIESVDKLAFSDWKRMLAIHLDGAFLTTKACLKYMYASGNGGSIIYMGSVHSKEASVLKAPYVTAKH
GLLGLCKVVAKEGGTHKVRANVICPGFVRTPLVDKQIPEQAKELGISEEDVIKKVMLKETVDGEFTTTDDVAQTALFFAS
FESNALTGQSLVVSHGWFME

Sequences:

>Translated_260_residues
MKLKNKIAIVTGAASGIGKEIALVYAKEGAKVAIADLNLDQASHVAEEIKSSGGQAMAVAMNVTDEAQVNQGVDKVADHF
GGVDVLVSNAGIQIIESVDKLAFSDWKRMLAIHLDGAFLTTKACLKYMYASGNGGSIIYMGSVHSKEASVLKAPYVTAKH
GLLGLCKVVAKEGGTHKVRANVICPGFVRTPLVDKQIPEQAKELGISEEDVIKKVMLKETVDGEFTTTDDVAQTALFFAS
FESNALTGQSLVVSHGWFME
>Mature_260_residues
MKLKNKIAIVTGAASGIGKEIALVYAKEGAKVAIADLNLDQASHVAEEIKSSGGQAMAVAMNVTDEAQVNQGVDKVADHF
GGVDVLVSNAGIQIIESVDKLAFSDWKRMLAIHLDGAFLTTKACLKYMYASGNGGSIIYMGSVHSKEASVLKAPYVTAKH
GLLGLCKVVAKEGGTHKVRANVICPGFVRTPLVDKQIPEQAKELGISEEDVIKKVMLKETVDGEFTTTDDVAQTALFFAS
FESNALTGQSLVVSHGWFME

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=267, Percent_Identity=31.8352059925094, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=30.8300395256917, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI31542939, Length=222, Percent_Identity=32.4324324324324, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=33.852140077821, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=34.020618556701, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI32483357, Length=261, Percent_Identity=29.5019157088123, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=26.2548262548263, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=32.7586206896552, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5031737, Length=189, Percent_Identity=29.1005291005291, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=29.1005291005291, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI40254986, Length=134, Percent_Identity=37.3134328358209, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI10190704, Length=258, Percent_Identity=24.031007751938, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI209862901, Length=267, Percent_Identity=28.4644194756554, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI19923983, Length=267, Percent_Identity=28.4644194756554, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI20149619, Length=210, Percent_Identity=26.1904761904762, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI157739938, Length=203, Percent_Identity=25.615763546798, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=27.0386266094421, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4503301, Length=213, Percent_Identity=25.3521126760563, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI210032110, Length=190, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=26.0700389105058, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI142976729, Length=216, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4758504, Length=209, Percent_Identity=28.7081339712919, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI126723191, Length=205, Percent_Identity=29.2682926829268, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI126723750, Length=264, Percent_Identity=26.1363636363636, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=23.3830845771144, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=31.3725490196078, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=30.5019305019305, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787905, Length=261, Percent_Identity=31.8007662835249, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1789057, Length=265, Percent_Identity=31.6981132075472, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=26.5384615384615, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=31.6602316602317, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=29.3893129770992, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=25.78125, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367175, Length=198, Percent_Identity=31.8181818181818, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1789378, Length=194, Percent_Identity=29.3814432989691, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786812, Length=262, Percent_Identity=28.6259541984733, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787526, Length=217, Percent_Identity=25.3456221198157, Blast_Score=72, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=257, Percent_Identity=28.4046692607004, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=35.8974358974359, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=30.2325581395349, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=29.4354838709677, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71982365, Length=194, Percent_Identity=31.9587628865979, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=232, Percent_Identity=27.5862068965517, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=262, Percent_Identity=27.8625954198473, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=230, Percent_Identity=27.3913043478261, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=29.2307692307692, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=28.6458333333333, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=212, Percent_Identity=32.0754716981132, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=26.6129032258064, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=23.5294117647059, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=273, Percent_Identity=24.9084249084249, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=190, Percent_Identity=31.5789473684211, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=26.7657992565056, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=188, Percent_Identity=26.063829787234, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=25.5905511811024, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17558628, Length=130, Percent_Identity=37.6923076923077, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=268, Percent_Identity=26.1194029850746, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=211, Percent_Identity=27.9620853080569, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=272, Percent_Identity=26.4705882352941, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=27.0676691729323, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=24.4094488188976, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=23.9852398523985, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=203, Percent_Identity=27.0935960591133, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=201, Percent_Identity=26.865671641791, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=220, Percent_Identity=25, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=24.0740740740741, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=25.5725190839695, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=235, Percent_Identity=26.8085106382979, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=26.7716535433071, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=197, Percent_Identity=27.4111675126904, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=27.1375464684015, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=25.187969924812, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=197, Percent_Identity=25.8883248730964, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=25.6505576208178, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=197, Percent_Identity=24.3654822335025, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=25.6916996047431, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=197, Percent_Identity=26.3959390862944, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=25.1824817518248, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=215, Percent_Identity=33.0232558139535, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324126, Length=262, Percent_Identity=25.9541984732824, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=26.6331658291457, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI18859837, Length=194, Percent_Identity=38.1443298969072, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=29.5719844357977, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI23397609, Length=262, Percent_Identity=31.6793893129771, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17737361, Length=213, Percent_Identity=29.1079812206573, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21357673, Length=275, Percent_Identity=29.8181818181818, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=24.2307692307692, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=28.4046692607004, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24640492, Length=191, Percent_Identity=28.7958115183246, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=24.1025641025641, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=27.9693486590038, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641232, Length=225, Percent_Identity=25.7777777777778, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648944, Length=232, Percent_Identity=27.1551724137931, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI221331218, Length=196, Percent_Identity=27.5510204081633, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24665243, Length=194, Percent_Identity=27.8350515463918, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=28.6821705426357, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24665247, Length=195, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221331216, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356301, Length=233, Percent_Identity=24.4635193133047, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24649181, Length=189, Percent_Identity=28.042328042328, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28571387, Length=226, Percent_Identity=23.4513274336283, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 27615; Mature: 27615

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKNKIAIVTGAASGIGKEIALVYAKEGAKVAIADLNLDQASHVAEEIKSSGGQAMAVA
CCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEE
MNVTDEAQVNQGVDKVADHFGGVDVLVSNAGIQIIESVDKLAFSDWKRMLAIHLDGAFLT
EECCCHHHHHCCHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHEEEEEECCHHHH
TKACLKYMYASGNGGSIIYMGSVHSKEASVLKAPYVTAKHGLLGLCKVVAKEGGTHKVRA
HHHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEE
NVICPGFVRTPLVDKQIPEQAKELGISEEDVIKKVMLKETVDGEFTTTDDVAQTALFFAS
EEECCCHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
FESNALTGQSLVVSHGWFME
CCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MKLKNKIAIVTGAASGIGKEIALVYAKEGAKVAIADLNLDQASHVAEEIKSSGGQAMAVA
CCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEE
MNVTDEAQVNQGVDKVADHFGGVDVLVSNAGIQIIESVDKLAFSDWKRMLAIHLDGAFLT
EECCCHHHHHCCHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHEEEEEECCHHHH
TKACLKYMYASGNGGSIIYMGSVHSKEASVLKAPYVTAKHGLLGLCKVVAKEGGTHKVRA
HHHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEE
NVICPGFVRTPLVDKQIPEQAKELGISEEDVIKKVMLKETVDGEFTTTDDVAQTALFFAS
EEECCCHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
FESNALTGQSLVVSHGWFME
CCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]