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The map label for this gene is argS [H]

Identifier: 148359603

GI number: 148359603

Start: 2387823

End: 2389583

Strand: Reverse

Name: argS [H]

Synonym: LPC_1515

Alternate gene names: 148359603

Gene position: 2389583-2387823 (Counterclockwise)

Preceding gene: 148359604

Following gene: 148359602

Centisome position: 66.81

GC content: 41.57

Gene sequence:

>1761_bases
ATGAAAGCTATAATCGAATATCTTTTGAAACAGGCATTAATTAATCTGCAACAATCAGGCGAAATGCCAATTGATTTGGA
GATTGAAATAAAAGTTGAGAATGCCAAAGATCCAGCTCATGGTGATTATGCGACTAATTTGGCACTGGTATTAGCTAAAC
CATGCCGACAAGCACCTAAAGTATTAGCCGAGCGATTGGTTGCAGTAATCCCCTCGGATCCGTCTGTAGAGAAAATTGAG
ATAGCCGGGGCAGGATTTATTAATTTTTTCATGCGCAACACGGCACGCTCGCTCATCATTTCTGAAATTTTGAATAAAGG
CAAGGAGTTTGGCCGAGGTAATTTAGGACAGAGCCAGAAAGTATTGATTGAATTTGTTTCTGCTAATCCAACAGGGCCTT
TACATGTAGGACATGGAAGAGGAGCTGCTTTCGGAGCAACTTTGGGTAATGTTTTAAAAGCTGCTGGTTACGATGTGACT
TTGGAATATTATGTCAATGATGCGGGCAGGCAAATGAATATTCTCGCTGTGAGTGTGTGGCTGCGCTACCTGGAATTGGC
AGGTGAGCCAATTGTTTTTCCGGCGAATGGCTATAAAGGTCAATATGTTTATGAGATTGCACAAGAGATGTGGTCAGAGC
AGGGTAATCAATTCGTGCATCCATGGATTTCGGTAGTAGAAAATTTACCTGCTGATGAACCCGAAGGTGGAGATAAAGAG
ACTTATATCGATGCGATCATCGCGCGAGCGCAATCCTTACTGGGCAAGGATGGGTTTGCTAACTTCCATCAACATGCTTT
AAAAACGGTATTGGATGACATAAAAGATGATTTGCAGGCGTTTGGTGTTCGTTTTGACAGTTGGTTTTCTGAGCAATCGT
TATTTGAAGATGGTTCTATTGAGAAAGGTATTCAGGCCTTGAAAGATAGAGGCCACACTTATGAAAGAGAAGGCGCTTTA
TGGTTTAGGGCAACTGATTTTGGTGATGAAAAAGATAGAGTATTAGTCCGGGCTAATGGGCAAACGACATATTTCGCTTC
TGATGTTGCTTATCACTGGAATAAATATGATAGAGGTTTTGATCGAGTCATTGATATTTTTGGTGCTGATCATCATGGTT
ATGTCACGAGAATTAAAACAGCTGTTAAGGCATTAGGACATGATGAAAGTGCTTTGGATGTCATTTTGGTGCAGTTTGCC
ATTCTGTATCGAGGTGGTGACAGGGTACAAATGTCTACTCGCAGTGGTTCATTTGTTACTTTGAGAGAGCTAAGAGAAGA
AGTAGGAAATGATGCGGCTCGTTATTTTTATGTGGCAAGAAAACCTGAACAACACATGGATTTTGACCTGGACCTGGCAA
AGTCCGAATCCAGTGACAATCCTGTGTATTATATTCAATATGCACATGCCCGTATCTGCAGTGTATTGAGGCAGTTAAAA
GAAAGGGGTTTGAAGTGGGATAAGGATATGGGACTTAAAAACCTTGATTTATTGGAGCAACAACATGAGACCACATTAAT
TTCTCTGATTGCCCGATATCCCGAAGTCATTCAATCTGCCGCTGCTTCTTGCGAGCCGCATCAGCTTGCTTACTATTTAA
GAGAGCTAGCCAATGGGTTACACAGTTATTATAATGCGATCCAGCTATTATGCGAACAAGAACAATTGCGATGTGCCCGT
TTGTGTTTGCTGGAGTCGGTTCGACAGGTTTTAAATAATGGTTTGGCTATATTAGGCGTATCAGCTCCTGAGAGTATGTG
A

Upstream 100 bases:

>100_bases
GTTTCTATTGTTGCAGTGATGGTGCTTCTGGGTTGAGAGCCTTTCCATATGGTATGAAAAAGAGCATAATATCGGTATTT
TTGACGGATAAATGAGAAGT

Downstream 100 bases:

>100_bases
TGGCAAAAGATTATGGAAATAGGCGTGCTGCACGTCGCAACAGAGGACCGCACCAGTTTTTGGTTATTATTGTGACTTTT
TTGTTTGGATATATAACCGC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MKAIIEYLLKQALINLQQSGEMPIDLEIEIKVENAKDPAHGDYATNLALVLAKPCRQAPKVLAERLVAVIPSDPSVEKIE
IAGAGFINFFMRNTARSLIISEILNKGKEFGRGNLGQSQKVLIEFVSANPTGPLHVGHGRGAAFGATLGNVLKAAGYDVT
LEYYVNDAGRQMNILAVSVWLRYLELAGEPIVFPANGYKGQYVYEIAQEMWSEQGNQFVHPWISVVENLPADEPEGGDKE
TYIDAIIARAQSLLGKDGFANFHQHALKTVLDDIKDDLQAFGVRFDSWFSEQSLFEDGSIEKGIQALKDRGHTYEREGAL
WFRATDFGDEKDRVLVRANGQTTYFASDVAYHWNKYDRGFDRVIDIFGADHHGYVTRIKTAVKALGHDESALDVILVQFA
ILYRGGDRVQMSTRSGSFVTLRELREEVGNDAARYFYVARKPEQHMDFDLDLAKSESSDNPVYYIQYAHARICSVLRQLK
ERGLKWDKDMGLKNLDLLEQQHETTLISLIARYPEVIQSAAASCEPHQLAYYLRELANGLHSYYNAIQLLCEQEQLRCAR
LCLLESVRQVLNNGLAILGVSAPESM

Sequences:

>Translated_586_residues
MKAIIEYLLKQALINLQQSGEMPIDLEIEIKVENAKDPAHGDYATNLALVLAKPCRQAPKVLAERLVAVIPSDPSVEKIE
IAGAGFINFFMRNTARSLIISEILNKGKEFGRGNLGQSQKVLIEFVSANPTGPLHVGHGRGAAFGATLGNVLKAAGYDVT
LEYYVNDAGRQMNILAVSVWLRYLELAGEPIVFPANGYKGQYVYEIAQEMWSEQGNQFVHPWISVVENLPADEPEGGDKE
TYIDAIIARAQSLLGKDGFANFHQHALKTVLDDIKDDLQAFGVRFDSWFSEQSLFEDGSIEKGIQALKDRGHTYEREGAL
WFRATDFGDEKDRVLVRANGQTTYFASDVAYHWNKYDRGFDRVIDIFGADHHGYVTRIKTAVKALGHDESALDVILVQFA
ILYRGGDRVQMSTRSGSFVTLRELREEVGNDAARYFYVARKPEQHMDFDLDLAKSESSDNPVYYIQYAHARICSVLRQLK
ERGLKWDKDMGLKNLDLLEQQHETTLISLIARYPEVIQSAAASCEPHQLAYYLRELANGLHSYYNAIQLLCEQEQLRCAR
LCLLESVRQVLNNGLAILGVSAPESM
>Mature_586_residues
MKAIIEYLLKQALINLQQSGEMPIDLEIEIKVENAKDPAHGDYATNLALVLAKPCRQAPKVLAERLVAVIPSDPSVEKIE
IAGAGFINFFMRNTARSLIISEILNKGKEFGRGNLGQSQKVLIEFVSANPTGPLHVGHGRGAAFGATLGNVLKAAGYDVT
LEYYVNDAGRQMNILAVSVWLRYLELAGEPIVFPANGYKGQYVYEIAQEMWSEQGNQFVHPWISVVENLPADEPEGGDKE
TYIDAIIARAQSLLGKDGFANFHQHALKTVLDDIKDDLQAFGVRFDSWFSEQSLFEDGSIEKGIQALKDRGHTYEREGAL
WFRATDFGDEKDRVLVRANGQTTYFASDVAYHWNKYDRGFDRVIDIFGADHHGYVTRIKTAVKALGHDESALDVILVQFA
ILYRGGDRVQMSTRSGSFVTLRELREEVGNDAARYFYVARKPEQHMDFDLDLAKSESSDNPVYYIQYAHARICSVLRQLK
ERGLKWDKDMGLKNLDLLEQQHETTLISLIARYPEVIQSAAASCEPHQLAYYLRELANGLHSYYNAIQLLCEQEQLRCAR
LCLLESVRQVLNNGLAILGVSAPESM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=600, Percent_Identity=23.3333333333333, Blast_Score=111, Evalue=2e-24,
Organism=Escherichia coli, GI1788184, Length=621, Percent_Identity=23.0273752012882, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71985061, Length=606, Percent_Identity=22.6072607260726, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71985068, Length=570, Percent_Identity=22.4561403508772, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320548, Length=562, Percent_Identity=26.1565836298932, Blast_Score=154, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6321883, Length=583, Percent_Identity=24.3567753001715, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI18859963, Length=605, Percent_Identity=22.9752066115702, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 65719; Mature: 65719

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIIEYLLKQALINLQQSGEMPIDLEIEIKVENAKDPAHGDYATNLALVLAKPCRQAPK
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
VLAERLVAVIPSDPSVEKIEIAGAGFINFFMRNTARSLIISEILNKGKEFGRGNLGQSQK
HHHHHHHEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
VLIEFVSANPTGPLHVGHGRGAAFGATLGNVLKAAGYDVTLEYYVNDAGRQMNILAVSVW
HHHHEECCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEHHHHHHHH
LRYLELAGEPIVFPANGYKGQYVYEIAQEMWSEQGNQFVHPWISVVENLPADEPEGGDKE
HHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCCCCCCCCHH
TYIDAIIARAQSLLGKDGFANFHQHALKTVLDDIKDDLQAFGVRFDSWFSEQSLFEDGSI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHCCCCCH
EKGIQALKDRGHTYEREGALWFRATDFGDEKDRVLVRANGQTTYFASDVAYHWNKYDRGF
HHHHHHHHHCCCCEECCCEEEEEECCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHCCHH
DRVIDIFGADHHGYVTRIKTAVKALGHDESALDVILVQFAILYRGGDRVQMSTRSGSFVT
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEE
LRELREEVGNDAARYFYVARKPEQHMDFDLDLAKSESSDNPVYYIQYAHARICSVLRQLK
HHHHHHHHCCCCEEEEEEECCCHHHCCCCCEECCCCCCCCCEEEEEEHHHHHHHHHHHHH
ERGLKWDKDMGLKNLDLLEQQHETTLISLIARYPEVIQSAAASCEPHQLAYYLRELANGL
HCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
HSYYNAIQLLCEQEQLRCARLCLLESVRQVLNNGLAILGVSAPESM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
>Mature Secondary Structure
MKAIIEYLLKQALINLQQSGEMPIDLEIEIKVENAKDPAHGDYATNLALVLAKPCRQAPK
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
VLAERLVAVIPSDPSVEKIEIAGAGFINFFMRNTARSLIISEILNKGKEFGRGNLGQSQK
HHHHHHHEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
VLIEFVSANPTGPLHVGHGRGAAFGATLGNVLKAAGYDVTLEYYVNDAGRQMNILAVSVW
HHHHEECCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEHHHHHHHH
LRYLELAGEPIVFPANGYKGQYVYEIAQEMWSEQGNQFVHPWISVVENLPADEPEGGDKE
HHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCCCCCCCCHH
TYIDAIIARAQSLLGKDGFANFHQHALKTVLDDIKDDLQAFGVRFDSWFSEQSLFEDGSI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHCCCCCH
EKGIQALKDRGHTYEREGALWFRATDFGDEKDRVLVRANGQTTYFASDVAYHWNKYDRGF
HHHHHHHHHCCCCEECCCEEEEEECCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHCCHH
DRVIDIFGADHHGYVTRIKTAVKALGHDESALDVILVQFAILYRGGDRVQMSTRSGSFVT
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEE
LRELREEVGNDAARYFYVARKPEQHMDFDLDLAKSESSDNPVYYIQYAHARICSVLRQLK
HHHHHHHHCCCCEEEEEEECCCHHHCCCCCEECCCCCCCCCEEEEEEHHHHHHHHHHHHH
ERGLKWDKDMGLKNLDLLEQQHETTLISLIARYPEVIQSAAASCEPHQLAYYLRELANGL
HCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
HSYYNAIQLLCEQEQLRCARLCLLESVRQVLNNGLAILGVSAPESM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA