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The map label for this gene is bioD [H]

Identifier: 148359004

GI number: 148359004

Start: 1691112

End: 1691750

Strand: Direct

Name: bioD [H]

Synonym: LPC_0889

Alternate gene names: 148359004

Gene position: 1691112-1691750 (Clockwise)

Preceding gene: 148359003

Following gene: 148359005

Centisome position: 47.28

GC content: 36.93

Gene sequence:

>639_bases
ATGAAACGATATTTTGTTACGGGTACTGACACTGATTGTGGTAAGACATTTGTAACCAATCAATTGGTTAATTATTTTTC
AAGTTCAGCAGCGATAAAACCTATAGCAAGCGGATGTGAGTACAGTAAAAATCAATTAGTAAATTCTGATGCACTTTTAC
ACCAGCAACAGAATCATTTGCCTTTGGAAATTATTAATCCCTGGCGATTTAGATTGCCAGTTTCGCCGCACTTATCAGCA
AGGGAGGATGGTGCAAGTATTGATGTTCATAAAGTGGCTGATTATTGCCTTAATTTGCAACTGAATGATATTAAGAAATT
ATTTATCGAAGGAGCCGGGGGATTAATGGTTCCTCTGAATGAGCAGGACACTTGGCTTGATTTTTTAAAATTAACCAGGA
TCCCTGTTATTTTAGTTGTGGGCATGAAGTTGGGTTGCATAAACCACACTTTGCTTACCCAGGAAGTGCTCGAAATAAAT
AAAATCAAATGTCAAGGATGGATTGCTAATTGCCTGGATCAGGACATGCTAATGCTTGATGAAAATATTAGTACCCTTGA
AGCCAAATTAAAATATCCTTTATTAGCCAGGACAAACTATGGCGGCAAGATTTCTGATATATGTTTAAGCTCCTTGTAA

Upstream 100 bases:

>100_bases
ATTACCCCAATTTTAAGTATGTCCTCTTCAACAGAGCAGCTCACATGCCTTTTCTGTCCCATACCGATTTATTTATTACA
ATGATGGATGAATTTATAAA

Downstream 100 bases:

>100_bases
TCGCAGTGAAATTTTATATCAAAACAGCACTATATACCTGATGTTATTGCTTGTTCTGCTTGCGCTATACCCATGGCAGC
AATTATAATGAAAAGTTAAA

Product: dethiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MKRYFVTGTDTDCGKTFVTNQLVNYFSSSAAIKPIASGCEYSKNQLVNSDALLHQQQNHLPLEIINPWRFRLPVSPHLSA
REDGASIDVHKVADYCLNLQLNDIKKLFIEGAGGLMVPLNEQDTWLDFLKLTRIPVILVVGMKLGCINHTLLTQEVLEIN
KIKCQGWIANCLDQDMLMLDENISTLEAKLKYPLLARTNYGGKISDICLSSL

Sequences:

>Translated_212_residues
MKRYFVTGTDTDCGKTFVTNQLVNYFSSSAAIKPIASGCEYSKNQLVNSDALLHQQQNHLPLEIINPWRFRLPVSPHLSA
REDGASIDVHKVADYCLNLQLNDIKKLFIEGAGGLMVPLNEQDTWLDFLKLTRIPVILVVGMKLGCINHTLLTQEVLEIN
KIKCQGWIANCLDQDMLMLDENISTLEAKLKYPLLARTNYGGKISDICLSSL
>Mature_212_residues
MKRYFVTGTDTDCGKTFVTNQLVNYFSSSAAIKPIASGCEYSKNQLVNSDALLHQQQNHLPLEIINPWRFRLPVSPHLSA
REDGASIDVHKVADYCLNLQLNDIKKLFIEGAGGLMVPLNEQDTWLDFLKLTRIPVILVVGMKLGCINHTLLTQEVLEIN
KIKCQGWIANCLDQDMLMLDENISTLEAKLKYPLLARTNYGGKISDICLSSL

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=202, Percent_Identity=38.1188118811881, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI87081944, Length=206, Percent_Identity=31.5533980582524, Blast_Score=104, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6324385, Length=156, Percent_Identity=32.0512820512821, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 23767; Mature: 23767

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYFVTGTDTDCGKTFVTNQLVNYFSSSAAIKPIASGCEYSKNQLVNSDALLHQQQNHL
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHCCCCHHHHHHHCCCC
PLEIINPWRFRLPVSPHLSAREDGASIDVHKVADYCLNLQLNDIKKLFIEGAGGLMVPLN
CEEEECCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECC
EQDTWLDFLKLTRIPVILVVGMKLGCINHTLLTQEVLEINKIKCQGWIANCLDQDMLMLD
CCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCHHHHHC
ENISTLEAKLKYPLLARTNYGGKISDICLSSL
CCHHHHHHHHCCCEEEECCCCCCHHHHHHHCC
>Mature Secondary Structure
MKRYFVTGTDTDCGKTFVTNQLVNYFSSSAAIKPIASGCEYSKNQLVNSDALLHQQQNHL
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHCCCCHHHHHHHCCCC
PLEIINPWRFRLPVSPHLSAREDGASIDVHKVADYCLNLQLNDIKKLFIEGAGGLMVPLN
CEEEECCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECC
EQDTWLDFLKLTRIPVILVVGMKLGCINHTLLTQEVLEINKIKCQGWIANCLDQDMLMLD
CCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCHHHHHC
ENISTLEAKLKYPLLARTNYGGKISDICLSSL
CCHHHHHHHHCCCEEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA