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The map label for this gene is yfdZ [H]

Identifier: 148358989

GI number: 148358989

Start: 1674199

End: 1675392

Strand: Direct

Name: yfdZ [H]

Synonym: LPC_0874

Alternate gene names: 148358989

Gene position: 1674199-1675392 (Clockwise)

Preceding gene: 148358987

Following gene: 148358990

Centisome position: 46.81

GC content: 40.79

Gene sequence:

>1194_bases
ATGAGTCAATTTCCACGCATTAAACGCTTACCCCCTTATGTATTTAATACAATAAACCAGCTTAAGATGGAAGCGCGGGC
GCGAGGAGAGGACATTATAGACTTTGGCATGGGGAATCCTGATCAACCAACCCCACCTCATATTGTTAATAAGCTTATAG
AGGTTGCTCAAAGGCCTGATACGCATCGATATTCAATGTCGAAAGGAATCCCGAGATTGCGTCGAGCGATGGCAACCTGG
TATCTTCGACATTATGATGTTCATCTGGACAGTGAAACACAAATATTAGCTACAATAGGATCTAAAGAGGGACTTGCACA
TTTGGCTTTGGCAATTTCAGGTCCAGGTGATACGGTGCTTGTTCCTGACCCTGCTTATCCTATCCATACCTACGGATTTA
TCATTGCTGGTGCTAATGTAAAGCAAATTCCTTTAATCGATGAAGTTCAATTTTTGGCTGCAGTAGAAGATGCTATTAAC
AGAACCTGGCCAAAACCCAAAGCCTTGGTTTTGAATTTTCCGGCAAATCCAAGTACTCACTGTGTCGAATATGAGTTTTT
TGAAAAGGTGGTTGATCTTGCCAAGCGTAATAACATTTGGATTATTCATGATTTGGCCTACGCAGATATAGTTTTTGATG
GGTATAAAGCCCCTTCGATTTTACAAGTTCCTGGTGCCATAGACATTGCAATTGAAACTTACTCAATGTCCAAATCTTAT
AATATGCCTGGCTGGCGTGTTGGGTTTGCTTGTGGTAACGAAGAGTTAGTAGCTGCCTTAACACGTATAAAATCCTACTT
GGATTACGGTACTTTTACTCCTATCCAGGTTGCTGCAATTACAGCACTGGAAGGCCCTGATGATTGTGTGTTGGAAATAA
GAAATCTTTATGAAAAACGACGCAATCTTTTGTGTGATGGACTGAATGACATTGGTTGGGAAGTGAGCAAACCTAAAGGG
ACCATGTTTGTTTGGGCACCTATTCCTCTCAATTACCGCGCTATGGGGTCTCTTGAGTTCAGTAAATATTTATTGAAAGA
AGCACAAGTTGCTGTTTCACCTGGTATAGGTTTTGGACAGCAAGGGGATGGTTATGTCCGATTCGGCTTAATTGAAAATA
AAGACAGAATAAGACAGGCCTTGAGAAATTTAAAAGCTCTGTTTAAAAGAGATGGTTTACTAAAGGCTATTTAG

Upstream 100 bases:

>100_bases
TTGCACTGCATGTTGCTCTGCGGTTTCTAGATTGATATTCATGATTTTAAAAAGTTCATTAGTTTATAATGGCTAACAGT
ATATCACAGAGGTCAATATT

Downstream 100 bases:

>100_bases
TGCAATGAATGTCATTATAAACACAGAGAGCGACTGTGATAGCAAAGAGGGCAAATTATTAAAATCGCAAGGTTTGGCAG
TACTTAATTTATTAGCATGC

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSQFPRIKRLPPYVFNTINQLKMEARARGEDIIDFGMGNPDQPTPPHIVNKLIEVAQRPDTHRYSMSKGIPRLRRAMATW
YLRHYDVHLDSETQILATIGSKEGLAHLALAISGPGDTVLVPDPAYPIHTYGFIIAGANVKQIPLIDEVQFLAAVEDAIN
RTWPKPKALVLNFPANPSTHCVEYEFFEKVVDLAKRNNIWIIHDLAYADIVFDGYKAPSILQVPGAIDIAIETYSMSKSY
NMPGWRVGFACGNEELVAALTRIKSYLDYGTFTPIQVAAITALEGPDDCVLEIRNLYEKRRNLLCDGLNDIGWEVSKPKG
TMFVWAPIPLNYRAMGSLEFSKYLLKEAQVAVSPGIGFGQQGDGYVRFGLIENKDRIRQALRNLKALFKRDGLLKAI

Sequences:

>Translated_397_residues
MSQFPRIKRLPPYVFNTINQLKMEARARGEDIIDFGMGNPDQPTPPHIVNKLIEVAQRPDTHRYSMSKGIPRLRRAMATW
YLRHYDVHLDSETQILATIGSKEGLAHLALAISGPGDTVLVPDPAYPIHTYGFIIAGANVKQIPLIDEVQFLAAVEDAIN
RTWPKPKALVLNFPANPSTHCVEYEFFEKVVDLAKRNNIWIIHDLAYADIVFDGYKAPSILQVPGAIDIAIETYSMSKSY
NMPGWRVGFACGNEELVAALTRIKSYLDYGTFTPIQVAAITALEGPDDCVLEIRNLYEKRRNLLCDGLNDIGWEVSKPKG
TMFVWAPIPLNYRAMGSLEFSKYLLKEAQVAVSPGIGFGQQGDGYVRFGLIENKDRIRQALRNLKALFKRDGLLKAI
>Mature_396_residues
SQFPRIKRLPPYVFNTINQLKMEARARGEDIIDFGMGNPDQPTPPHIVNKLIEVAQRPDTHRYSMSKGIPRLRRAMATWY
LRHYDVHLDSETQILATIGSKEGLAHLALAISGPGDTVLVPDPAYPIHTYGFIIAGANVKQIPLIDEVQFLAAVEDAINR
TWPKPKALVLNFPANPSTHCVEYEFFEKVVDLAKRNNIWIIHDLAYADIVFDGYKAPSILQVPGAIDIAIETYSMSKSYN
MPGWRVGFACGNEELVAALTRIKSYLDYGTFTPIQVAAITALEGPDDCVLEIRNLYEKRRNLLCDGLNDIGWEVSKPKGT
MFVWAPIPLNYRAMGSLEFSKYLLKEAQVAVSPGIGFGQQGDGYVRFGLIENKDRIRQALRNLKALFKRDGLLKAI

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=387, Percent_Identity=24.8062015503876, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI56713254, Length=387, Percent_Identity=24.8062015503876, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI95147551, Length=393, Percent_Identity=21.3740458015267, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI169881279, Length=393, Percent_Identity=21.3740458015267, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI169881281, Length=243, Percent_Identity=22.6337448559671, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4507369, Length=346, Percent_Identity=22.8323699421965, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788722, Length=394, Percent_Identity=64.2131979695431, Blast_Score=540, Evalue=1e-155,
Organism=Escherichia coli, GI1786816, Length=343, Percent_Identity=27.1137026239067, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788627, Length=351, Percent_Identity=24.7863247863248, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71994472, Length=393, Percent_Identity=24.6819338422392, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71994476, Length=393, Percent_Identity=24.6819338422392, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17567369, Length=395, Percent_Identity=23.5443037974684, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17567663, Length=349, Percent_Identity=25.214899713467, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=398, Percent_Identity=21.356783919598, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320317, Length=346, Percent_Identity=24.8554913294798, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573069, Length=420, Percent_Identity=24.7619047619048, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24646114, Length=420, Percent_Identity=24.7619047619048, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28573067, Length=420, Percent_Identity=24.7619047619048, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28573065, Length=420, Percent_Identity=24.7619047619048, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44519; Mature: 44388

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFPRIKRLPPYVFNTINQLKMEARARGEDIIDFGMGNPDQPTPPHIVNKLIEVAQRPD
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCC
THRYSMSKGIPRLRRAMATWYLRHYDVHLDSETQILATIGSKEGLAHLALAISGPGDTVL
CCHHHHHCCCHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCCCCEEEEEEEECCCCEEE
VPDPAYPIHTYGFIIAGANVKQIPLIDEVQFLAAVEDAINRTWPKPKALVLNFPANPSTH
ECCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
CVEYEFFEKVVDLAKRNNIWIIHDLAYADIVFDGYKAPSILQVPGAIDIAIETYSMSKSY
EEEHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCCCCCEEECCCEEEEEEEEEECCCCC
NMPGWRVGFACGNEELVAALTRIKSYLDYGTFTPIQVAAITALEGPDDCVLEIRNLYEKR
CCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
RNLLCDGLNDIGWEVSKPKGTMFVWAPIPLNYRAMGSLEFSKYLLKEAQVAVSPGIGFGQ
HHHHHCCCCCCCCEEECCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHEEECCCCCCCC
QGDGYVRFGLIENKDRIRQALRNLKALFKRDGLLKAI
CCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHCC
>Mature Secondary Structure 
SQFPRIKRLPPYVFNTINQLKMEARARGEDIIDFGMGNPDQPTPPHIVNKLIEVAQRPD
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCC
THRYSMSKGIPRLRRAMATWYLRHYDVHLDSETQILATIGSKEGLAHLALAISGPGDTVL
CCHHHHHCCCHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCCCCEEEEEEEECCCCEEE
VPDPAYPIHTYGFIIAGANVKQIPLIDEVQFLAAVEDAINRTWPKPKALVLNFPANPSTH
ECCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
CVEYEFFEKVVDLAKRNNIWIIHDLAYADIVFDGYKAPSILQVPGAIDIAIETYSMSKSY
EEEHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCCCCCEEECCCEEEEEEEEEECCCCC
NMPGWRVGFACGNEELVAALTRIKSYLDYGTFTPIQVAAITALEGPDDCVLEIRNLYEKR
CCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
RNLLCDGLNDIGWEVSKPKGTMFVWAPIPLNYRAMGSLEFSKYLLKEAQVAVSPGIGFGQ
HHHHHCCCCCCCCEEECCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHEEECCCCCCCC
QGDGYVRFGLIENKDRIRQALRNLKALFKRDGLLKAI
CCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]