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The map label for this gene is trpB [H]

Identifier: 148358846

GI number: 148358846

Start: 1511885

End: 1513084

Strand: Direct

Name: trpB [H]

Synonym: LPC_0729

Alternate gene names: 148358846

Gene position: 1511885-1513084 (Clockwise)

Preceding gene: 148358845

Following gene: 148358847

Centisome position: 42.27

GC content: 42.33

Gene sequence:

>1200_bases
ATGATTAAAAAAGAGCTTCCAGATGAGTTTGGCCATTTTGGCCCATATGGCGGTATGTTTGTAGCCGATACATTAGTTTC
TGCTTTAAAACAATTAGAGCATGCCTATACCAAATATCGTAACGATCAGGATTTTCTGTCTGAGTTACACACAGAATTAA
AAGATTATGTGGGGCGGCCCAATCCTCTATACCATGCCGTACACTTAAGTAAAAAGATAGGCGGTGCACAAATTTATCTC
AAGCGTGAAGATTTAAATCATACCGGCGCTCATAAAATCAATAATACCATTGGACAAGCCTTACTCGCCAAACGCATGGG
GAAAACTCGAGTGATCGCGGAAACAGGCGCAGGTCAACATGGCGTTGCAACTGCTACAGTTGCCGCTAAATTTGGGTTTC
AATGCGTTGTGTACATGGGGTCAGAAGACATTAAGCGTCAATCCAGTAATGTTTATAGAATGAAATTGTTAGGCGCTGAA
GTGGTGCCTGTCACTTCAGGATCAAAGACGTTGAAAGATGCTTTAAATGAAGCATTGAGAGATTGGGTGAGTCATGTCGA
CGACACGTTTTATATTATTGGTACTGTTGCAGGTCCCCATCCTTATCCTCAAATGGTAAGAGATTTTCAAGCGATTATTG
GTGTTGAAGCTCGAGCTCAGCATATGGAAAAAACAGGCCGTTTGCCAGATGCTTTGGTAGCTTGTGTCGGAGGTGGATCC
AATGCAATAGGCTTGTTTTATCCCTTTTTGAATGATCAGTCTGTCATGATTTATGGGGTTGAAGCAGGAGGGAAAGGCAT
AGAAACCGGTGAGCATTCAGCATCTCTGATTGCTGGAAAACCTGGTGTGTTACACGGTAATAGAACCTATTTATTGTGTG
ATGAGTATGGACAGGTGAAAGACACTCATTCAGTATCAGCCGGTCTGGATTATCCTGGAGTTGGGCCTGAACATGCTTAT
TTAAAAGATACTGGACGGGTCATTTATAAAGCAATAAACGATTCCGAGGCCCTGGATGCCTTTCGCCTGTTAACTCATAC
GGAAGGAATTATTCCAGCATTAGAATCTAGCCACGCGGTAGCCTATGCCATACAATTGGCTAAAACGATGTCAAAAGAAC
AGAGCATCATAGTCAATCTATCTGGCCGTGGTGATAAAGATATGCATACAGTAGCTGCTATTGACGGTATAACAATTTAA

Upstream 100 bases:

>100_bases
CATCCTTATGCAGTGGATGTGTGCAGTGGTATAGAAGCTTCACCCGGAGTAAAAGATCATTTGAAAATGAGCCGATTTAT
AAAGGCAATATGGGGATAGT

Downstream 100 bases:

>100_bases
TTTTGATAAATTATTCAGGTACAACATGAACCGTATTGATAAGACTCTGGAAAAATTAAAAGCCAATAGAAAAAAAATGT
TAAGTCCTTATATTACTGCA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MIKKELPDEFGHFGPYGGMFVADTLVSALKQLEHAYTKYRNDQDFLSELHTELKDYVGRPNPLYHAVHLSKKIGGAQIYL
KREDLNHTGAHKINNTIGQALLAKRMGKTRVIAETGAGQHGVATATVAAKFGFQCVVYMGSEDIKRQSSNVYRMKLLGAE
VVPVTSGSKTLKDALNEALRDWVSHVDDTFYIIGTVAGPHPYPQMVRDFQAIIGVEARAQHMEKTGRLPDALVACVGGGS
NAIGLFYPFLNDQSVMIYGVEAGGKGIETGEHSASLIAGKPGVLHGNRTYLLCDEYGQVKDTHSVSAGLDYPGVGPEHAY
LKDTGRVIYKAINDSEALDAFRLLTHTEGIIPALESSHAVAYAIQLAKTMSKEQSIIVNLSGRGDKDMHTVAAIDGITI

Sequences:

>Translated_399_residues
MIKKELPDEFGHFGPYGGMFVADTLVSALKQLEHAYTKYRNDQDFLSELHTELKDYVGRPNPLYHAVHLSKKIGGAQIYL
KREDLNHTGAHKINNTIGQALLAKRMGKTRVIAETGAGQHGVATATVAAKFGFQCVVYMGSEDIKRQSSNVYRMKLLGAE
VVPVTSGSKTLKDALNEALRDWVSHVDDTFYIIGTVAGPHPYPQMVRDFQAIIGVEARAQHMEKTGRLPDALVACVGGGS
NAIGLFYPFLNDQSVMIYGVEAGGKGIETGEHSASLIAGKPGVLHGNRTYLLCDEYGQVKDTHSVSAGLDYPGVGPEHAY
LKDTGRVIYKAINDSEALDAFRLLTHTEGIIPALESSHAVAYAIQLAKTMSKEQSIIVNLSGRGDKDMHTVAAIDGITI
>Mature_399_residues
MIKKELPDEFGHFGPYGGMFVADTLVSALKQLEHAYTKYRNDQDFLSELHTELKDYVGRPNPLYHAVHLSKKIGGAQIYL
KREDLNHTGAHKINNTIGQALLAKRMGKTRVIAETGAGQHGVATATVAAKFGFQCVVYMGSEDIKRQSSNVYRMKLLGAE
VVPVTSGSKTLKDALNEALRDWVSHVDDTFYIIGTVAGPHPYPQMVRDFQAIIGVEARAQHMEKTGRLPDALVACVGGGS
NAIGLFYPFLNDQSVMIYGVEAGGKGIETGEHSASLIAGKPGVLHGNRTYLLCDEYGQVKDTHSVSAGLDYPGVGPEHAY
LKDTGRVIYKAINDSEALDAFRLLTHTEGIIPALESSHAVAYAIQLAKTMSKEQSIIVNLSGRGDKDMHTVAAIDGITI

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=381, Percent_Identity=55.6430446194226, Blast_Score=443, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321412, Length=401, Percent_Identity=56.1097256857855, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43252; Mature: 43252

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKELPDEFGHFGPYGGMFVADTLVSALKQLEHAYTKYRNDQDFLSELHTELKDYVGRP
CCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
NPLYHAVHLSKKIGGAQIYLKREDLNHTGAHKINNTIGQALLAKRMGKTRVIAETGAGQH
CCHHHHEEHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
GVATATVAAKFGFQCVVYMGSEDIKRQSSNVYRMKLLGAEVVPVTSGSKTLKDALNEALR
CCHHHHHHHHCCCEEEEEECCHHHHHHCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHH
DWVSHVDDTFYIIGTVAGPHPYPQMVRDFQAIIGVEARAQHMEKTGRLPDALVACVGGGS
HHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCCC
NAIGLFYPFLNDQSVMIYGVEAGGKGIETGEHSASLIAGKPGVLHGNRTYLLCDEYGQVK
CEEEEEEEEECCCEEEEEEEECCCCCCCCCCCCCEEEECCCCEEECCEEEEEECCCCCCC
DTHSVSAGLDYPGVGPEHAYLKDTGRVIYKAINDSEALDAFRLLTHTEGIIPALESSHAV
CCCCCCCCCCCCCCCCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHH
AYAIQLAKTMSKEQSIIVNLSGRGDKDMHTVAAIDGITI
HHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MIKKELPDEFGHFGPYGGMFVADTLVSALKQLEHAYTKYRNDQDFLSELHTELKDYVGRP
CCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
NPLYHAVHLSKKIGGAQIYLKREDLNHTGAHKINNTIGQALLAKRMGKTRVIAETGAGQH
CCHHHHEEHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
GVATATVAAKFGFQCVVYMGSEDIKRQSSNVYRMKLLGAEVVPVTSGSKTLKDALNEALR
CCHHHHHHHHCCCEEEEEECCHHHHHHCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHH
DWVSHVDDTFYIIGTVAGPHPYPQMVRDFQAIIGVEARAQHMEKTGRLPDALVACVGGGS
HHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCCC
NAIGLFYPFLNDQSVMIYGVEAGGKGIETGEHSASLIAGKPGVLHGNRTYLLCDEYGQVK
CEEEEEEEEECCCEEEEEEEECCCCCCCCCCCCCEEEECCCCEEECCEEEEEECCCCCCC
DTHSVSAGLDYPGVGPEHAYLKDTGRVIYKAINDSEALDAFRLLTHTEGIIPALESSHAV
CCCCCCCCCCCCCCCCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHH
AYAIQLAKTMSKEQSIIVNLSGRGDKDMHTVAAIDGITI
HHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA