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The map label for this gene is ruvC [H]

Identifier: 148358829

GI number: 148358829

Start: 1496041

End: 1496565

Strand: Direct

Name: ruvC [H]

Synonym: LPC_0712

Alternate gene names: 148358829

Gene position: 1496041-1496565 (Clockwise)

Preceding gene: 148358828

Following gene: 148358830

Centisome position: 41.83

GC content: 41.14

Gene sequence:

>525_bases
ATGACGATTATATTAGGGATAGATCCAGGCTCACGGGTTACAGGATATGGATTGATTAAAGAATCTGACCGTAAAATCGC
GTACATCGATAGCGGCTGTATTCGCACATCAAACGATGCGGAATTAAGTCATAAATTATTGCAAATATATGATGGAATAT
GTGAGCTAATGGATCACTATTCCCCAACTGAGGTTGCTATTGAGCAGATATTTATGCATAACAATCCTAATTCAGCTTTG
AAATTAGGACATGCGCGGGGGGTTGCCATGGTAGCAGCAGCCTCACATCGTGCGAAAATCTGTGAGTATTCAGCAAGAGA
AATAAAGCAAAGTGTAGTTGGTTATGGGGCCGCTGAAAAAGATCAAGTAAGTCATATGGTTGTAGAGCTTCTTCAGCTCA
ATCGAGCTCCTCAAAAAGACGCTGCCGATGCTTTGGCAATAGCAATATGTCATAGCCATATGAGAAATGGTTTGTCAAAA
TTAATCGGTTCAAGAGGAACGAAACGTAGGAGGATGAGACTATGA

Upstream 100 bases:

>100_bases
GTTTAATTAAACTGATTGATATGCTGGAAGATTTGGATGATGTCCAAGAAGTTTACAGCAATGCTGAATTTTCTGAAAAA
ATATTAGAATCAATGAATTA

Downstream 100 bases:

>100_bases
TAGGCTGGCTCCATGGTCAAATTATAGATAAGCATCAGCCAGGAAAATTGGTTCTTGATGTCAATGGAGTAGGATATGAT
GTAGAAACATCTTTGAATAC

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MTIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDAELSHKLLQIYDGICELMDHYSPTEVAIEQIFMHNNPNSAL
KLGHARGVAMVAAASHRAKICEYSAREIKQSVVGYGAAEKDQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSK
LIGSRGTKRRRMRL

Sequences:

>Translated_174_residues
MTIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDAELSHKLLQIYDGICELMDHYSPTEVAIEQIFMHNNPNSAL
KLGHARGVAMVAAASHRAKICEYSAREIKQSVVGYGAAEKDQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSK
LIGSRGTKRRRMRL
>Mature_173_residues
TIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDAELSHKLLQIYDGICELMDHYSPTEVAIEQIFMHNNPNSALK
LGHARGVAMVAAASHRAKICEYSAREIKQSVVGYGAAEKDQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSKL
IGSRGTKRRRMRL

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=174, Percent_Identity=54.0229885057471, Blast_Score=163, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 19141; Mature: 19010

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDAELSHKLLQIYDGICELMDHY
CEEEEECCCCCCEEEEEEEECCCCEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHCC
SPTEVAIEQIFMHNNPNSALKLGHARGVAMVAAASHRAKICEYSAREIKQSVVGYGAAEK
CHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSKLIGSRGTKRRRMRL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure 
TIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDAELSHKLLQIYDGICELMDHY
EEEEECCCCCCEEEEEEEECCCCEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHCC
SPTEVAIEQIFMHNNPNSALKLGHARGVAMVAAASHRAKICEYSAREIKQSVVGYGAAEK
CHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSKLIGSRGTKRRRMRL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA