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The map label for this gene is cfa [H]

Identifier: 148358715

GI number: 148358715

Start: 1370157

End: 1371284

Strand: Reverse

Name: cfa [H]

Synonym: LPC_0594

Alternate gene names: 148358715

Gene position: 1371284-1370157 (Counterclockwise)

Preceding gene: 148358716

Following gene: 148358714

Centisome position: 38.34

GC content: 36.79

Gene sequence:

>1128_bases
ATGGATATTAAAAAAAACAAAGCAAAAACATTTGTCAATTACATGCTTCAGCTAGCCAATATCAATATCAATGGTCAGAC
ACCTTGGGATATACAAATTTATAATGATGAGTTCTATTCCAGATTATTGCGTGATGCCGATTTGGGTCTGGGTGAAAGTT
ACATGGAAGGTTGGTGGGATTGTCAACGAATTGATTTATTTATTTCAAAACTGATTAACGCAAATCTTGAGTCCAAAATT
AAAATTAATTTTAAATTGGCCTTTAATGTCTTTTTATCAAAAATATTGAACCTGCAAACCCCAAAACGTTCTCTGCATGT
TGGTAGACAACATTATGATCGAGGAAATGATCTGTTTCAGATTATGCTTGATAGCAATATGAACTACACTTGCGGCTATT
GGAAAAAAGCTGAAAATTTGGAGCAAGCCCAACTCGACAAGCTCGATCTGGCCTGCAGAAAACTCTGCCTTAAACCCGGT
ATGAAATTGCTGGATATCGGATGTGGATGGGGAGGACTGGCAAAATATGCTGCTGAAAACTATGGGGTATCAGTAGTTGG
CATAACGATATCACAGCAACAATACGAGTTAGCTAAAACGCGCTGTGCTCATTTGCCGGTTGAAATCCGATTTCAGGATT
ATAGAGACTTAAATGAAAAATTCGATCGTATAGTCTCCTTAGGGATGTTTGAGCATGTTGGTTACAAGAATTACCGAAAA
TACATGGAAATTGTCCATCAATGTTTAAATGATGATGGTTTGTTCTTATTACACACTATAGGTTCCAATGAAAGTGTCAC
AAAAGCCACACCCTGGATTTCAAAATATATTTTTCCCAATGGAATGATTCCATCCATCATGCAAATAGGCCAAGCTTCCG
AAAAATTATTCGTTATGGAGGATTGGCATAATTTTGGAGCTGATTATTACAAAACTTTAATGGCATGGCATGAAAATTTC
AATCAGGGATGGGAGCAAATTAAATCCCAATATAGCGAAAAATTCTTTCGTATGTGGAATTATTATTTGCTCTCTTGTGC
TGGCGCTTTTGATGCCAGAATGTTGCAATTATGGCAGATTGTTTTTTCAAAGAAAGGAATTCAAGGAGGATACTCTGCGC
CGAGGTAA

Upstream 100 bases:

>100_bases
TTATTTATTATCTTGTTACAGCCATAACAGACGCTTTGAGTGGCTGATGATGTTGCATTGATTGAATGTTTCAACATCCT
TTATAAAAAGGGAGTTTGAT

Downstream 100 bases:

>100_bases
ATGGTTTAAACGATTTATTCCGCATCGTAATACCTTCACCAGCAAACCTGGTTTTCCATGCCATGAAATTGGCAAGATTA
TTCATATATCCCGTTAATTT

Product: cyclopropane fatty acyl phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MDIKKNKAKTFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDADLGLGESYMEGWWDCQRIDLFISKLINANLESKI
KINFKLAFNVFLSKILNLQTPKRSLHVGRQHYDRGNDLFQIMLDSNMNYTCGYWKKAENLEQAQLDKLDLACRKLCLKPG
MKLLDIGCGWGGLAKYAAENYGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSLGMFEHVGYKNYRK
YMEIVHQCLNDDGLFLLHTIGSNESVTKATPWISKYIFPNGMIPSIMQIGQASEKLFVMEDWHNFGADYYKTLMAWHENF
NQGWEQIKSQYSEKFFRMWNYYLLSCAGAFDARMLQLWQIVFSKKGIQGGYSAPR

Sequences:

>Translated_375_residues
MDIKKNKAKTFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDADLGLGESYMEGWWDCQRIDLFISKLINANLESKI
KINFKLAFNVFLSKILNLQTPKRSLHVGRQHYDRGNDLFQIMLDSNMNYTCGYWKKAENLEQAQLDKLDLACRKLCLKPG
MKLLDIGCGWGGLAKYAAENYGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSLGMFEHVGYKNYRK
YMEIVHQCLNDDGLFLLHTIGSNESVTKATPWISKYIFPNGMIPSIMQIGQASEKLFVMEDWHNFGADYYKTLMAWHENF
NQGWEQIKSQYSEKFFRMWNYYLLSCAGAFDARMLQLWQIVFSKKGIQGGYSAPR
>Mature_375_residues
MDIKKNKAKTFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDADLGLGESYMEGWWDCQRIDLFISKLINANLESKI
KINFKLAFNVFLSKILNLQTPKRSLHVGRQHYDRGNDLFQIMLDSNMNYTCGYWKKAENLEQAQLDKLDLACRKLCLKPG
MKLLDIGCGWGGLAKYAAENYGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSLGMFEHVGYKNYRK
YMEIVHQCLNDDGLFLLHTIGSNESVTKATPWISKYIFPNGMIPSIMQIGQASEKLFVMEDWHNFGADYYKTLMAWHENF
NQGWEQIKSQYSEKFFRMWNYYLLSCAGAFDARMLQLWQIVFSKKGIQGGYSAPR

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=364, Percent_Identity=56.5934065934066, Blast_Score=441, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI133904226, Length=401, Percent_Identity=29.426433915212, Blast_Score=158, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 43784; Mature: 43784

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKKNKAKTFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDADLGLGESYMEGWWD
CCCCHHHHHHHHHHHHHHHEEEECCCCCEEEEEECHHHHHHHHHHCCCCCCHHHHHHHHH
CQRIDLFISKLINANLESKIKINFKLAFNVFLSKILNLQTPKRSLHVGRQHYDRGNDLFQ
HHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEE
IMLDSNMNYTCGYWKKAENLEQAQLDKLDLACRKLCLKPGMKLLDIGCGWGGLAKYAAEN
EEECCCCCCEECCCHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHC
YGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSLGMFEHVGYKNYRK
CCEEEEEEEECHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
YMEIVHQCLNDDGLFLLHTIGSNESVTKATPWISKYIFPNGMIPSIMQIGQASEKLFVME
HHHHHHHHHCCCCEEEEEEECCCCCCCHHCHHHHHHCCCCCCHHHHHHHCCCCCEEEEEE
DWHNFGADYYKTLMAWHENFNQGWEQIKSQYSEKFFRMWNYYLLSCAGAFDARMLQLWQI
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
VFSKKGIQGGYSAPR
HHHHCCCCCCCCCCC
>Mature Secondary Structure
MDIKKNKAKTFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDADLGLGESYMEGWWD
CCCCHHHHHHHHHHHHHHHEEEECCCCCEEEEEECHHHHHHHHHHCCCCCCHHHHHHHHH
CQRIDLFISKLINANLESKIKINFKLAFNVFLSKILNLQTPKRSLHVGRQHYDRGNDLFQ
HHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEE
IMLDSNMNYTCGYWKKAENLEQAQLDKLDLACRKLCLKPGMKLLDIGCGWGGLAKYAAEN
EEECCCCCCEECCCHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHC
YGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSLGMFEHVGYKNYRK
CCEEEEEEEECHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
YMEIVHQCLNDDGLFLLHTIGSNESVTKATPWISKYIFPNGMIPSIMQIGQASEKLFVME
HHHHHHHHHCCCCEEEEEEECCCCCCCHHCHHHHHHCCCCCCHHHHHHHCCCCCEEEEEE
DWHNFGADYYKTLMAWHENFNQGWEQIKSQYSEKFFRMWNYYLLSCAGAFDARMLQLWQI
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
VFSKKGIQGGYSAPR
HHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]