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The map label for this gene is yfhR [C]

Identifier: 148358661

GI number: 148358661

Start: 3115429

End: 3116226

Strand: Direct

Name: yfhR [C]

Synonym: LPC_0537

Alternate gene names: 148358661

Gene position: 3115429-3116226 (Clockwise)

Preceding gene: 148358663

Following gene: 148358644

Centisome position: 87.11

GC content: 38.85

Gene sequence:

>798_bases
ATGCTGAAACAAATTGTGCTAACCGGCCTAGTTATTATAGGGATTGTCATTACGCTAATGTACTTATTTCAGCGCCACCT
CATTTATTTCCCTAATAGACATACCCCAAAGTTGGAAGATTACAATGCATCGGATATGAAAGTAGTTTCCTTGCGTACAA
AAGATAATTTACATTTAAAATCCTGGTATAAACCTGCAAGCAAGCATCGCCCTACAATACTCTATTTGCATGGGAATGCT
GGGCATATTGGTTACAGAATGCCTTTGGTTCGTGAATTTATTGACGCTGGTTTAGGCGTATTTTTATTAGAATATCGTGG
TTATGGAGGCAATCCGGGCAAACCTGGCGAGAAAGGTCTTTATGCAGATGGAGAAACAGCCATTGAATTTTTAATTCAAC
ATGGTGTGCCATCAAAGCGCGTGATTCTATATGGGGAATCCATAGGTACCGGAGTAGCAACTCATCTTGCCACAAAATAC
CCGGTTTGTGCGGTTATACTTCAATCACCTTTTACATCACTAACCAGGCTTGCCCAGTATCACTACCCATTGAACTTCCT
TAAACCCTGGGATCAATATAATTCACTTGCCCGTATGAAAAAAATTCATGTCCCCATTCTGGTTTTGCATGGAAAATTGG
ATCAGATAGTACCGTATCAAGAGGGCTTAAATGTTTTTAATGAAGCCAATGAACCTAAAAAAATGGTTTCTTTTGACGAC
AAAGAACATAATGATTTGTGGAGCGCTGATAATTTTTCGAGGGAAATTATTCAATTTGCTTTAAACCAGTGTTCCTAA

Upstream 100 bases:

>100_bases
TTTGAGGCAATTCGCCCATCATCGATATTGGCTTCCAATCGATTAAGGTGCATTATAATCAAATTAATACAATATATTTT
AAATCCTTCTTAAGGTGATC

Downstream 100 bases:

>100_bases
CTTTTGTGGATAGTTCATTGTTAAGGCATTTTCATCATCGACGTTATTATTGAACTCAATCATCCATTTCCGCAAAGGCC
ATTGAAAATCTCCTTTCAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MLKQIVLTGLVIIGIVITLMYLFQRHLIYFPNRHTPKLEDYNASDMKVVSLRTKDNLHLKSWYKPASKHRPTILYLHGNA
GHIGYRMPLVREFIDAGLGVFLLEYRGYGGNPGKPGEKGLYADGETAIEFLIQHGVPSKRVILYGESIGTGVATHLATKY
PVCAVILQSPFTSLTRLAQYHYPLNFLKPWDQYNSLARMKKIHVPILVLHGKLDQIVPYQEGLNVFNEANEPKKMVSFDD
KEHNDLWSADNFSREIIQFALNQCS

Sequences:

>Translated_265_residues
MLKQIVLTGLVIIGIVITLMYLFQRHLIYFPNRHTPKLEDYNASDMKVVSLRTKDNLHLKSWYKPASKHRPTILYLHGNA
GHIGYRMPLVREFIDAGLGVFLLEYRGYGGNPGKPGEKGLYADGETAIEFLIQHGVPSKRVILYGESIGTGVATHLATKY
PVCAVILQSPFTSLTRLAQYHYPLNFLKPWDQYNSLARMKKIHVPILVLHGKLDQIVPYQEGLNVFNEANEPKKMVSFDD
KEHNDLWSADNFSREIIQFALNQCS
>Mature_265_residues
MLKQIVLTGLVIIGIVITLMYLFQRHLIYFPNRHTPKLEDYNASDMKVVSLRTKDNLHLKSWYKPASKHRPTILYLHGNA
GHIGYRMPLVREFIDAGLGVFLLEYRGYGGNPGKPGEKGLYADGETAIEFLIQHGVPSKRVILYGESIGTGVATHLATKY
PVCAVILQSPFTSLTRLAQYHYPLNFLKPWDQYNSLARMKKIHVPILVLHGKLDQIVPYQEGLNVFNEANEPKKMVSFDD
KEHNDLWSADNFSREIIQFALNQCS

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI49355781, Length=266, Percent_Identity=28.5714285714286, Blast_Score=110, Evalue=9e-25,
Organism=Homo sapiens, GI71051602, Length=188, Percent_Identity=34.0425531914894, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI71051600, Length=193, Percent_Identity=33.160621761658, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI151301175, Length=215, Percent_Identity=31.6279069767442, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI194306564, Length=182, Percent_Identity=31.8681318681319, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI194306562, Length=182, Percent_Identity=31.8681318681319, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI32451492, Length=209, Percent_Identity=33.4928229665072, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI32528310, Length=209, Percent_Identity=33.9712918660287, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI109689718, Length=200, Percent_Identity=32, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI24308097, Length=200, Percent_Identity=32, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI226510965, Length=270, Percent_Identity=28.5185185185185, Blast_Score=115, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71988362, Length=184, Percent_Identity=33.695652173913, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17532877, Length=203, Percent_Identity=27.5862068965517, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17566318, Length=187, Percent_Identity=28.8770053475936, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25143554, Length=157, Percent_Identity=31.8471337579618, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985392, Length=203, Percent_Identity=27.0935960591133, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71985387, Length=202, Percent_Identity=25.7425742574257, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324009, Length=280, Percent_Identity=30.7142857142857, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI17137566, Length=277, Percent_Identity=29.6028880866426, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281362521, Length=233, Percent_Identity=29.1845493562232, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI281362519, Length=233, Percent_Identity=29.1845493562232, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28571878, Length=233, Percent_Identity=29.1845493562232, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24655464, Length=190, Percent_Identity=29.4736842105263, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24655467, Length=190, Percent_Identity=29.4736842105263, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 30181; Mature: 30181

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKQIVLTGLVIIGIVITLMYLFQRHLIYFPNRHTPKLEDYNASDMKVVSLRTKDNLHLK
CHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEEEEEECCCCCCHH
SWYKPASKHRPTILYLHGNAGHIGYRMPLVREFIDAGLGVFLLEYRGYGGNPGKPGEKGL
HHCCCHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCHHEEEEEECCCCCCCCCCCCCCC
YADGETAIEFLIQHGVPSKRVILYGESIGTGVATHLATKYPVCAVILQSPFTSLTRLAQY
CCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHCHHHHHHHHHHH
HYPLNFLKPWDQYNSLARMKKIHVPILVLHGKLDQIVPYQEGLNVFNEANEPKKMVSFDD
CCCCHHCCCHHHHHHHHHHHHHCCCEEEEECCHHHCCCHHHHHHHHHCCCCCHHHHCCCC
KEHNDLWSADNFSREIIQFALNQCS
CCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKQIVLTGLVIIGIVITLMYLFQRHLIYFPNRHTPKLEDYNASDMKVVSLRTKDNLHLK
CHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEEEEEECCCCCCHH
SWYKPASKHRPTILYLHGNAGHIGYRMPLVREFIDAGLGVFLLEYRGYGGNPGKPGEKGL
HHCCCHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCHHEEEEEECCCCCCCCCCCCCCC
YADGETAIEFLIQHGVPSKRVILYGESIGTGVATHLATKYPVCAVILQSPFTSLTRLAQY
CCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHCHHHHHHHHHHH
HYPLNFLKPWDQYNSLARMKKIHVPILVLHGKLDQIVPYQEGLNVFNEANEPKKMVSFDD
CCCCHHCCCHHHHHHHHHHHHHCCCEEEEECCHHHCCCHHHHHHHHHCCCCCHHHHCCCC
KEHNDLWSADNFSREIIQFALNQCS
CCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]