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The map label for this gene is mraY

Identifier: 148358648

GI number: 148358648

Start: 3130493

End: 3131578

Strand: Reverse

Name: mraY

Synonym: LPC_0524

Alternate gene names: 148358648

Gene position: 3131578-3130493 (Counterclockwise)

Preceding gene: 148358647

Following gene: 148358649

Centisome position: 87.56

GC content: 41.44

Gene sequence:

>1086_bases
ATGCTCTATTGGTTAACGCAGTTATTGCAGGGACAATATCATGCGTTTAGAGTTTTTCAATATTTGACATTCAGGTCTAT
TTTAGCTTCATTAACTGCCCTTATAGTGGGTTTGTTATGTGGCCCATTAATGATCCGCTGGTTAAGAGGGCTGCAAATAG
GTCAAATGGTTAGGAGTGATGGTCCCCAAACCCATTTATCAAAGGCGGGAACTCCCACTATGGGGGGCGTTTTGATTTTA
TTGGCTATCACTGTGAGTTGCTTGCTTTGGTGCGATTTAAGACAAACAAGCCTGTGGCTGGTGCTCTTGGTTACCTTGGC
TAATGGTTTGGTAGGTTGGGTTGATGATTATCGCAAGTTGGTATTAAAAAATAGCAAAGGATTACCTGGTCGTTGGAAAT
ATTTTTGGCAGTCAGTCATTGCTTTAGTTGCTGTCTCTTATTTGTATTGGAATGCCAGTTTGCCAGTACATACCCAGCTC
ACAGTTCCTTTTTTTAAAACGGTCACTTGGGATCTGGGCGTTTTTTTTCCTGTACTTGCCTATTTCGTTATTGTTGGAAG
CAGTAATGCAGTGAATTTAACTGATGGGCTGGATGGCTTGGCTATTATGCCAATAGTAATGGTGGCTGGTGCCTTGGGTG
TGTTTGCCTATGCATCGAGTAACGCCGTATACTCTAATTATTTAGGAATCCCTTATGTGCCCAATACTGGTGAGCTAACG
ATTTTTTGTTCTTCTATTGTTGGTGCCGGCCTGGGTTTTCTTTGGTATAACAGTTATCCTGCCCAAGTTTTCATGGGCGA
TGTGGGCTCTTTGGCGTTAGGAGCAGCTTTAGGGATAGTTGCGATTGTAGTTAGGCAAGAACTTGTTCTGCTCATTATGG
GTGGATTATTTGTAATTGAGACGCTTTCTGTCATATTACAAGTGGGTTATTTTAAATATTCAGGCGGAAAAAGATTATTC
AGGATGGCCCCATTACATCACCATTTTGAATTAAAGGGGTGGTCAGAGCCCAAAGTGATAGTAAGGTTTTGGATTATTAC
GGTTGTATTTGTGTTATGCGGATTGGCTACTTTAAAACTTCGATAG

Upstream 100 bases:

>100_bases
CGACAGGAATGTGGTATGCTTGGCCACTTTTTTGCCCCATTAAAGGAATTATGCTCAATAAAAGTCATTGAGCATAATTT
TAAGAACAAGAGGAATAATT

Downstream 100 bases:

>100_bases
ACAAGGTGCATTCATGAATCATTCCTTATATTTGGTAGCAGGGCTGGGTAAGACGGGACTCTCTATAGCAAGATACCTGA
AGAGAAATAATAAATCGTTT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLRGLQIGQMVRSDGPQTHLSKAGTPTMGGVLIL
LAITVSCLLWCDLRQTSLWLVLLVTLANGLVGWVDDYRKLVLKNSKGLPGRWKYFWQSVIALVAVSYLYWNASLPVHTQL
TVPFFKTVTWDLGVFFPVLAYFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLGIPYVPNTGELT
IFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAIVVRQELVLLIMGGLFVIETLSVILQVGYFKYSGGKRLF
RMAPLHHHFELKGWSEPKVIVRFWIITVVFVLCGLATLKLR

Sequences:

>Translated_361_residues
MLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLRGLQIGQMVRSDGPQTHLSKAGTPTMGGVLIL
LAITVSCLLWCDLRQTSLWLVLLVTLANGLVGWVDDYRKLVLKNSKGLPGRWKYFWQSVIALVAVSYLYWNASLPVHTQL
TVPFFKTVTWDLGVFFPVLAYFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLGIPYVPNTGELT
IFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAIVVRQELVLLIMGGLFVIETLSVILQVGYFKYSGGKRLF
RMAPLHHHFELKGWSEPKVIVRFWIITVVFVLCGLATLKLR
>Mature_361_residues
MLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLRGLQIGQMVRSDGPQTHLSKAGTPTMGGVLIL
LAITVSCLLWCDLRQTSLWLVLLVTLANGLVGWVDDYRKLVLKNSKGLPGRWKYFWQSVIALVAVSYLYWNASLPVHTQL
TVPFFKTVTWDLGVFFPVLAYFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLGIPYVPNTGELT
IFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAIVVRQELVLLIMGGLFVIETLSVILQVGYFKYSGGKRLF
RMAPLHHHFELKGWSEPKVIVRFWIITVVFVLCGLATLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=61.4958448753463, Blast_Score=430, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_LEGPA (Q5X1S3)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_124975.1
- STRING:   Q5X1S3
- GeneID:   3118259
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp2670
- LegioList:   lpp2670
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   LPNE297246:LPP2670-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 39869; Mature: 39869

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13991710)-; HASH(0x146791ec)-; HASH(0x14666e0c)-; HASH(0x14673518)-; HASH(0x14666d34)-; HASH(0x14666e24)-; HASH(0x14654bdc)-; HASH(0x13c61488)-; HASH(0x14654b7c)-; HASH(0x14672b28)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLRGLQIGQMVRSD
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
GPQTHLSKAGTPTMGGVLILLAITVSCLLWCDLRQTSLWLVLLVTLANGLVGWVDDYRKL
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
VLKNSKGLPGRWKYFWQSVIALVAVSYLYWNASLPVHTQLTVPFFKTVTWDLGVFFPVLA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHH
YFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLGIPYVPNTGELT
HHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCEE
IFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAIVVRQELVLLIMGGLFVIE
EEHHHHHHCCHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGYFKYSGGKRLFRMAPLHHHFELKGWSEPKVIVRFWIITVVFVLCGLATLKL
HHHHHHHHHCEEECCCCCEEHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCHHHHCC
R
H
>Mature Secondary Structure
MLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLRGLQIGQMVRSD
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
GPQTHLSKAGTPTMGGVLILLAITVSCLLWCDLRQTSLWLVLLVTLANGLVGWVDDYRKL
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
VLKNSKGLPGRWKYFWQSVIALVAVSYLYWNASLPVHTQLTVPFFKTVTWDLGVFFPVLA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHH
YFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLGIPYVPNTGELT
HHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCEE
IFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAIVVRQELVLLIMGGLFVIE
EEHHHHHHCCHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGYFKYSGGKRLFRMAPLHHHFELKGWSEPKVIVRFWIITVVFVLCGLATLKL
HHHHHHHHHCEEECCCCCEEHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCHHHHCC
R
H

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA