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The map label for this gene is ftsY [H]

Identifier: 148358595

GI number: 148358595

Start: 3193519

End: 3194586

Strand: Reverse

Name: ftsY [H]

Synonym: LPC_0468

Alternate gene names: 148358595

Gene position: 3194586-3193519 (Counterclockwise)

Preceding gene: 148358587

Following gene: 148358596

Centisome position: 89.32

GC content: 43.91

Gene sequence:

>1068_bases
ATGATTAAATGGTTTAAACGAAATCAAAATTCCGAACCAAATTTGGATACCGAAGAGCAACAAGATCATGCCGAAAGCAG
CATGGAATCCAGGCTTGAAGAACCCCAGGAACTGACTGTCAAAGAGCCTTCGCCCAAAGAAAGTATTTTTGCCCGGTTTA
GGAAAGGCCTTAGCAAAACCCGTCATCAATTGGGGGAAGGCATAAGTCGGCTGCTGTTAGGTAAAAAAGAAATCAGCCAG
GAGTTACTCGAAGAGCTGGAGACCTTATTAATTAGTGCTGATTTAGGTTTGGACACCACTCAAGACGTATTGAAACAGCT
AAATGAAGGCTTGGCACGAAAGCAACTGTCTAATGGTGAAGCAGTTTATCAGACTCTAAAGACAAATTTTGCAACGATTT
TGAGCCCAGAAGAGAAACCGCTTTCCATAGAAACTGAAGACGGTTCTCCCTTTGTCATATTAATGGTTGGTGTCAATGGA
GCCGGTAAAACAACCACGATTGGTAAACTAGCCAAACAATTCCAAAAGCAGGGAAAAAAAGTCATGTTAGCTGCGGGCGA
TACGTTTCGGGCTGCTGCGGTGGAGCAATTGCATGTATGGGGCGAAAGAAATGGCATACCTGTTATTGCCCAGCATACCG
GCGCTGACAGTGCCTCAGTAATTTTTGATGCCCTTCAGGCTGCCAAAGCGAGAAAAATAGATGTTTTAATCGCTGATACA
GCAGGGCGTTTGCATACTCAAAGCAATTTAATGGAAGAGTTGAAAAAAGTGAAAAGAGTCATGCAGAAACTCGATCCCAA
GGCGCCTCATGAAACCATGTTGGTATTGGATGCGAGTATTGGGCAGAACGCCTTGGCTCAGGCAAAGCAGTTTCATGAAG
CAGTACAATTAACTGGAATTACTATGACCAAGCTTGATGGGACAGCCAAAGGCGGGATATTATTTGCTATAGCGAATGAT
TTGGGGATACCTTTTCGTTATTTAGGGGTAGGGGAGGGCATTGAAGATTTGAGGCCCTTTGACGCAGCGCAATTTGTTAG
TGCGATATTCGATGATGATCACATTTGA

Upstream 100 bases:

>100_bases
GAGAGTAGCATCATAAGAGAAATGAGTGGTTTGTGCACAATGTCACCTCAAAGCTAAAAAGATGATAGAATTTCATATTT
TTAAGGAATTGTACACTAAA

Downstream 100 bases:

>100_bases
CCAGGTTAGTAAACGTTATCCGGGGGGCTTTGAGGCATTAAGCCAAGTTAATTTTTCTTTGCAAAAAGGAGAAATGGTCT
TTCTTACTGGCCATTCAGGC

Product: cell division membrane protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MIKWFKRNQNSEPNLDTEEQQDHAESSMESRLEEPQELTVKEPSPKESIFARFRKGLSKTRHQLGEGISRLLLGKKEISQ
ELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGEAVYQTLKTNFATILSPEEKPLSIETEDGSPFVILMVGVNG
AGKTTTIGKLAKQFQKQGKKVMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQAAKARKIDVLIADT
AGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGITMTKLDGTAKGGILFAIAND
LGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI

Sequences:

>Translated_355_residues
MIKWFKRNQNSEPNLDTEEQQDHAESSMESRLEEPQELTVKEPSPKESIFARFRKGLSKTRHQLGEGISRLLLGKKEISQ
ELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGEAVYQTLKTNFATILSPEEKPLSIETEDGSPFVILMVGVNG
AGKTTTIGKLAKQFQKQGKKVMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQAAKARKIDVLIADT
AGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGITMTKLDGTAKGGILFAIAND
LGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI
>Mature_355_residues
MIKWFKRNQNSEPNLDTEEQQDHAESSMESRLEEPQELTVKEPSPKESIFARFRKGLSKTRHQLGEGISRLLLGKKEISQ
ELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGEAVYQTLKTNFATILSPEEKPLSIETEDGSPFVILMVGVNG
AGKTTTIGKLAKQFQKQGKKVMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQAAKARKIDVLIADT
AGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGITMTKLDGTAKGGILFAIAND
LGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=282, Percent_Identity=30.8510638297872, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226371618, Length=247, Percent_Identity=33.1983805668016, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI23308697, Length=333, Percent_Identity=28.2282282282282, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI295424842, Length=333, Percent_Identity=28.2282282282282, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI89061728, Length=143, Percent_Identity=32.1678321678322, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789874, Length=310, Percent_Identity=65.1612903225806, Blast_Score=393, Evalue=1e-110,
Organism=Escherichia coli, GI1788963, Length=276, Percent_Identity=34.7826086956522, Blast_Score=167, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI17539958, Length=273, Percent_Identity=27.8388278388278, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI193206261, Length=311, Percent_Identity=28.9389067524116, Blast_Score=117, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6325345, Length=199, Percent_Identity=38.1909547738693, Blast_Score=142, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6320498, Length=330, Percent_Identity=27.5757575757576, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI17647949, Length=286, Percent_Identity=31.8181818181818, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24641198, Length=374, Percent_Identity=25.1336898395722, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 38992; Mature: 38992

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKWFKRNQNSEPNLDTEEQQDHAESSMESRLEEPQELTVKEPSPKESIFARFRKGLSKT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RHQLGEGISRLLLGKKEISQELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGE
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCH
AVYQTLKTNFATILSPEEKPLSIETEDGSPFVILMVGVNGAGKTTTIGKLAKQFQKQGKK
HHHHHHHHHHHEEECCCCCCCEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCE
VMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQAAKARKIDVLIADT
EEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECC
AGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCE
TMTKLDGTAKGGILFAIANDLGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI
EEEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MIKWFKRNQNSEPNLDTEEQQDHAESSMESRLEEPQELTVKEPSPKESIFARFRKGLSKT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RHQLGEGISRLLLGKKEISQELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGE
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCH
AVYQTLKTNFATILSPEEKPLSIETEDGSPFVILMVGVNGAGKTTTIGKLAKQFQKQGKK
HHHHHHHHHHHEEECCCCCCCEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCE
VMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQAAKARKIDVLIADT
EEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECC
AGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCE
TMTKLDGTAKGGILFAIANDLGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI
EEEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]