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The map label for this gene is infC [H]

Identifier: 148358549

GI number: 148358549

Start: 3241641

End: 3242030

Strand: Reverse

Name: infC [H]

Synonym: LPC_0421

Alternate gene names: 148358549

Gene position: 3242030-3241641 (Counterclockwise)

Preceding gene: 148358548

Following gene: 148358550

Centisome position: 90.65

GC content: 40.51

Gene sequence:

>390_bases
TTGGATTTGGTGGAAATATCTCCAACAGCCAAACCCCCTGTTTGTCGTATTATGGATTATGGTAAGTTTCTCTTTGAACT
GAGTAAAAAACAAGCTGAAGCAAAAAAGAAGCAAAAACAAATTCAGGTCAAAGAATTAAAATTCCGTCCTACGACGGAAG
ATGGAGATTATCAGGTCAAGCTACGCAACCTGATCCGTTTCCTCAATCATGGTGATAAGGTCAAAATCACATTGCGTTTT
CGCGGTCGTGAAATGGCTCATCAAGAACTCGGTATGAAGATTTTGGAACGTTTGCAAGCCGACACGGCTGATGTAGCTAT
AGTGGAGCAGCATGCAAAACGTGAAGGAAGACAATTACTGATGGTATTATCACCCAAAAAAACCAAGTAA

Upstream 100 bases:

>100_bases
ACAGATCACTGTACCTGAGGTACGCTTAATTGATGTCGATGGTAACCAGGCAGGAATTGTATCAACGCGAGAAGCGTTAA
GGGCAGCAGAAGAAAGCGGA

Downstream 100 bases:

>100_bases
CGAATGCGGAGTATATTGTTATGCCGAAGTTAAAGTCACATCGTGGAGCAGCTAAACGCTTCCGAAAGACAGCGAGTGGA
GCGATTAAACGTCGCGGCGC

Product: translational initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MDLVEISPTAKPPVCRIMDYGKFLFELSKKQAEAKKKQKQIQVKELKFRPTTEDGDYQVKLRNLIRFLNHGDKVKITLRF
RGREMAHQELGMKILERLQADTADVAIVEQHAKREGRQLLMVLSPKKTK

Sequences:

>Translated_129_residues
MDLVEISPTAKPPVCRIMDYGKFLFELSKKQAEAKKKQKQIQVKELKFRPTTEDGDYQVKLRNLIRFLNHGDKVKITLRF
RGREMAHQELGMKILERLQADTADVAIVEQHAKREGRQLLMVLSPKKTK
>Mature_129_residues
MDLVEISPTAKPPVCRIMDYGKFLFELSKKQAEAKKKQKQIQVKELKFRPTTEDGDYQVKLRNLIRFLNHGDKVKITLRF
RGREMAHQELGMKILERLQADTADVAIVEQHAKREGRQLLMVLSPKKTK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=128, Percent_Identity=69.53125, Blast_Score=168, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 15032; Mature: 15032

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLVEISPTAKPPVCRIMDYGKFLFELSKKQAEAKKKQKQIQVKELKFRPTTEDGDYQVK
CCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEH
LRNLIRFLNHGDKVKITLRFRGREMAHQELGMKILERLQADTADVAIVEQHAKREGRQLL
HHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEE
MVLSPKKTK
EEECCCCCC
>Mature Secondary Structure
MDLVEISPTAKPPVCRIMDYGKFLFELSKKQAEAKKKQKQIQVKELKFRPTTEDGDYQVK
CCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEH
LRNLIRFLNHGDKVKITLRFRGREMAHQELGMKILERLQADTADVAIVEQHAKREGRQLL
HHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEE
MVLSPKKTK
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA