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The map label for this gene is glsA [H]

Identifier: 148358453

GI number: 148358453

Start: 340620

End: 341552

Strand: Direct

Name: glsA [H]

Synonym: LPC_0319

Alternate gene names: 148358453

Gene position: 340620-341552 (Clockwise)

Preceding gene: 148358452

Following gene: 148358457

Centisome position: 9.52

GC content: 43.52

Gene sequence:

>933_bases
ATGTCATCAAAATTGCTTACCATCCAATTGTTAGAAGAGCTTGTGCATGCTGCCGAATTAAATCAAGAAGGCAAAACTGC
GGATTATATCCCTGAACTGGCGAATGTTAATCAGGAATTGACAGCAATTGCGGTGCAACCTTTGGGTGAGAAAACCTTGG
CTTATAGTAATAATCCACTTCATCCAGTGACTTTGCAAAGCACTGGGAAGATGATCCCTTTGATTGGTTTGCTTGAGGAG
TTTGGTGCTGATCAATTGTTTGAATGGGTTAAGGTGGAGCCTTCGGGTGATGATTTTGCTTCCATTACCCGCTTGGAGCA
GTTTGGACCTAAACCGTCAAATCCCATGCTGAACGCTGGCGCAATTGCCTTATGTTCACGTATTCCAGGCGTGGGTGAGC
AGCAGTTTAGATGGTTAGAACATTGGGTACAAAAATTATTTAATCAACGTCTCAGTATTAATCCTCTGGTGTTTGCCTCT
GAAAAACGAACCGGTAATCGTAACCGCGCTCTCGCCTATTTGCTGAAAAGCAGAAACAATCTTGGAGCTGATGTTCATGA
AACCCTCGATTTGTATTTTGCGCTATGTTCCTATGAAGCCATGTTGGATCAGATGCTGTACTTACCCGCTGTGTTAGCGA
ATAGAGGGCAAGATCCGGACACGGGTGAACAAATCCTTTCTATCGAAACCTGTAAAATTACTTTGGCTATCATGGCAACC
TGTGGATTATATGATGAAACAGGTACTCATATGGTTAAAACAGGGATGCCAGCTAAAAGTGGAGTGTCTGGTTATACCAT
CGCGGTTGTTCCCGGTAAAGCCGGTATTGTGGTGTTGAGTCCAAGAGTGAATGCGAAAGGAAATAGCATACGAGGTGAAA
TAATGCTGGAAGGTTTGTCCAAAGCAATGGGTTGGCATTTTGCGTTACCTTAA

Upstream 100 bases:

>100_bases
CATCCTTAGCCTATTTATTAGCAATATCCTTTCAAAATAAAATATTTGTCTTAATGTGCTAAATTTACCATAATAGCCCC
TTTTTTAATCCAATAGTACT

Downstream 100 bases:

>100_bases
TTTTAAGTCCTGTAAATAAGATAACGCTGTATGGTGTTATAAGGAAAAATTGAAATATGGTTTGTAGTGCTTCAGACGTG
ATTTAACTCAGCATTTTAAT

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSSKLLTIQLLEELVHAAELNQEGKTADYIPELANVNQELTAIAVQPLGEKTLAYSNNPLHPVTLQSTGKMIPLIGLLEE
FGADQLFEWVKVEPSGDDFASITRLEQFGPKPSNPMLNAGAIALCSRIPGVGEQQFRWLEHWVQKLFNQRLSINPLVFAS
EKRTGNRNRALAYLLKSRNNLGADVHETLDLYFALCSYEAMLDQMLYLPAVLANRGQDPDTGEQILSIETCKITLAIMAT
CGLYDETGTHMVKTGMPAKSGVSGYTIAVVPGKAGIVVLSPRVNAKGNSIRGEIMLEGLSKAMGWHFALP

Sequences:

>Translated_310_residues
MSSKLLTIQLLEELVHAAELNQEGKTADYIPELANVNQELTAIAVQPLGEKTLAYSNNPLHPVTLQSTGKMIPLIGLLEE
FGADQLFEWVKVEPSGDDFASITRLEQFGPKPSNPMLNAGAIALCSRIPGVGEQQFRWLEHWVQKLFNQRLSINPLVFAS
EKRTGNRNRALAYLLKSRNNLGADVHETLDLYFALCSYEAMLDQMLYLPAVLANRGQDPDTGEQILSIETCKITLAIMAT
CGLYDETGTHMVKTGMPAKSGVSGYTIAVVPGKAGIVVLSPRVNAKGNSIRGEIMLEGLSKAMGWHFALP
>Mature_309_residues
SSKLLTIQLLEELVHAAELNQEGKTADYIPELANVNQELTAIAVQPLGEKTLAYSNNPLHPVTLQSTGKMIPLIGLLEEF
GADQLFEWVKVEPSGDDFASITRLEQFGPKPSNPMLNAGAIALCSRIPGVGEQQFRWLEHWVQKLFNQRLSINPLVFASE
KRTGNRNRALAYLLKSRNNLGADVHETLDLYFALCSYEAMLDQMLYLPAVLANRGQDPDTGEQILSIETCKITLAIMATC
GLYDETGTHMVKTGMPAKSGVSGYTIAVVPGKAGIVVLSPRVNAKGNSIRGEIMLEGLSKAMGWHFALP

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=301, Percent_Identity=34.5514950166113, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI20336214, Length=288, Percent_Identity=35.0694444444444, Blast_Score=164, Evalue=1e-40,
Organism=Escherichia coli, GI1786693, Length=284, Percent_Identity=35.2112676056338, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1787804, Length=284, Percent_Identity=32.7464788732394, Blast_Score=144, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI17507019, Length=302, Percent_Identity=34.4370860927152, Blast_Score=170, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI17532727, Length=291, Percent_Identity=33.6769759450172, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI193204073, Length=308, Percent_Identity=32.4675324675325, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI193204075, Length=310, Percent_Identity=32.258064516129, Blast_Score=151, Evalue=4e-37,
Organism=Drosophila melanogaster, GI281363241, Length=308, Percent_Identity=32.7922077922078, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24653164, Length=308, Percent_Identity=32.7922077922078, Blast_Score=164, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24653162, Length=308, Percent_Identity=32.7922077922078, Blast_Score=164, Evalue=5e-41,
Organism=Drosophila melanogaster, GI281363239, Length=308, Percent_Identity=32.7922077922078, Blast_Score=164, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24653156, Length=308, Percent_Identity=32.7922077922078, Blast_Score=164, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24653158, Length=308, Percent_Identity=32.7922077922078, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI116008307, Length=308, Percent_Identity=32.7922077922078, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24653166, Length=308, Percent_Identity=32.7922077922078, Blast_Score=164, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 33894; Mature: 33762

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKLLTIQLLEELVHAAELNQEGKTADYIPELANVNQELTAIAVQPLGEKTLAYSNNPL
CCCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHEEEEEECCCCCCCEEECCCCC
HPVTLQSTGKMIPLIGLLEEFGADQLFEWVKVEPSGDDFASITRLEQFGPKPSNPMLNAG
CEEEECCCCCCHHHHHHHHHHCHHHHHHHEECCCCCCCHHHHHHHHHCCCCCCCCCCCCH
AIALCSRIPGVGEQQFRWLEHWVQKLFNQRLSINPLVFASEKRTGNRNRALAYLLKSRNN
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCC
LGADVHETLDLYFALCSYEAMLDQMLYLPAVLANRGQDPDTGEQILSIETCKITLAIMAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEHHHHEEEEHHHH
CGLYDETGTHMVKTGMPAKSGVSGYTIAVVPGKAGIVVLSPRVNAKGNSIRGEIMLEGLS
HCCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHH
KAMGWHFALP
HHCCCCCCCC
>Mature Secondary Structure 
SSKLLTIQLLEELVHAAELNQEGKTADYIPELANVNQELTAIAVQPLGEKTLAYSNNPL
CCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHEEEEEECCCCCCCEEECCCCC
HPVTLQSTGKMIPLIGLLEEFGADQLFEWVKVEPSGDDFASITRLEQFGPKPSNPMLNAG
CEEEECCCCCCHHHHHHHHHHCHHHHHHHEECCCCCCCHHHHHHHHHCCCCCCCCCCCCH
AIALCSRIPGVGEQQFRWLEHWVQKLFNQRLSINPLVFASEKRTGNRNRALAYLLKSRNN
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCC
LGADVHETLDLYFALCSYEAMLDQMLYLPAVLANRGQDPDTGEQILSIETCKITLAIMAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEHHHHEEEEHHHH
CGLYDETGTHMVKTGMPAKSGVSGYTIAVVPGKAGIVVLSPRVNAKGNSIRGEIMLEGLS
HCCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHH
KAMGWHFALP
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA