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The map label for this gene is mhpC [H]

Identifier: 148358447

GI number: 148358447

Start: 334851

End: 335645

Strand: Direct

Name: mhpC [H]

Synonym: LPC_0313

Alternate gene names: 148358447

Gene position: 334851-335645 (Clockwise)

Preceding gene: 148358441

Following gene: 148358448

Centisome position: 9.36

GC content: 40.25

Gene sequence:

>795_bases
ATGGCCACACTCAAGATTCATGATGTTGATATTTATTATGAGCTCTATGGGCAAGGTAAACCACTGGTTTTAATTGCAGG
CTATTGCTGTGATCACACCTTTTGGAACGCCATGCTCCATGAGTTGGCTGAAGAATTCCAGGTATTGATATTTGACAATC
GCGGGATAGGGCAAACGAGAGACAATGGAGATTCTTTTACATTAGAAGCTCAGGCGGATGACATCATGGCTTTCTTGGAG
CAATTAGGTTTTAGAAACCCTTCTATTCTGGGGCAATCAATGGGTGGGGCTATTGCTCAATTGCTTGCCAGAAAGCATGG
TAAAAAAATCAGTAAATTGGTTATTTTAAATTCGGTTGCAAAATTCAATACGAGAGCAAACCAGGCTATGGAAAGCCTTT
TGAATTTGCGAAAGGAGAATATTTCATTCGATTTATTAATAGAGGCTGGAATACCATGGTTTTTTTCAAGCGAATATTTG
GCTGAGCCTAAAAATATCGCTACTTTTAAAGAGAATTTGAAAAATAATCCTTATCCGCAATCCTTACAAGATCAAGTGCG
ACAATTTAGAAGCATACCACCATTTGATTCCCGCGGGTGGCTACATGAAATTAAAGTGCCCACACTAGTTATAGCAGCAG
AGGACGATATACTGACCTTGCCTGCAGAAAGTCAACAACTGGCACAAAGGATCCCTAATGCTCAATTCATTACAATTCCT
GGCGGACATTCCAGTCCCTTGGAACACCCCGCGTTAGTCAATGATGCCATACTAAAATTTTTAACCTCTTCCTAA

Upstream 100 bases:

>100_bases
TGACGTAATTCATCGAAACAATAGATAATTGAGGCGAAAAGTCATTGAATGAAGCGTTGCGTTTGTTCGTCAAAAAAATC
AATTAAGGAGTTTTTGCGAC

Downstream 100 bases:

>100_bases
AAAGGTGCTGAATAAATGGAAATTTACGAAATGTACATTGATGGAAAATTTACTTTAGCCAAAAGCGGAACTACTCGCGA
CATTTTTGATCCGGCTAACG

Product: lipolytic enzyme

Products: NA

Alternate protein names: Aminohydrolase [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MATLKIHDVDIYYELYGQGKPLVLIAGYCCDHTFWNAMLHELAEEFQVLIFDNRGIGQTRDNGDSFTLEAQADDIMAFLE
QLGFRNPSILGQSMGGAIAQLLARKHGKKISKLVILNSVAKFNTRANQAMESLLNLRKENISFDLLIEAGIPWFFSSEYL
AEPKNIATFKENLKNNPYPQSLQDQVRQFRSIPPFDSRGWLHEIKVPTLVIAAEDDILTLPAESQQLAQRIPNAQFITIP
GGHSSPLEHPALVNDAILKFLTSS

Sequences:

>Translated_264_residues
MATLKIHDVDIYYELYGQGKPLVLIAGYCCDHTFWNAMLHELAEEFQVLIFDNRGIGQTRDNGDSFTLEAQADDIMAFLE
QLGFRNPSILGQSMGGAIAQLLARKHGKKISKLVILNSVAKFNTRANQAMESLLNLRKENISFDLLIEAGIPWFFSSEYL
AEPKNIATFKENLKNNPYPQSLQDQVRQFRSIPPFDSRGWLHEIKVPTLVIAAEDDILTLPAESQQLAQRIPNAQFITIP
GGHSSPLEHPALVNDAILKFLTSS
>Mature_263_residues
ATLKIHDVDIYYELYGQGKPLVLIAGYCCDHTFWNAMLHELAEEFQVLIFDNRGIGQTRDNGDSFTLEAQADDIMAFLEQ
LGFRNPSILGQSMGGAIAQLLARKHGKKISKLVILNSVAKFNTRANQAMESLLNLRKENISFDLLIEAGIPWFFSSEYLA
EPKNIATFKENLKNNPYPQSLQDQVRQFRSIPPFDSRGWLHEIKVPTLVIAAEDDILTLPAESQQLAQRIPNAQFITIPG
GHSSPLEHPALVNDAILKFLTSS

Specific function: May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Hydrolase RutD family [H]

Homologues:

Organism=Escherichia coli, GI1787244, Length=244, Percent_Identity=22.9508196721311, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR019913 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 29597; Mature: 29466

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLKIHDVDIYYELYGQGKPLVLIAGYCCDHTFWNAMLHELAEEFQVLIFDNRGIGQTR
CCEEEEEEEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCC
DNGDSFTLEAQADDIMAFLEQLGFRNPSILGQSMGGAIAQLLARKHGKKISKLVILNSVA
CCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
KFNTRANQAMESLLNLRKENISFDLLIEAGIPWFFSSEYLAEPKNIATFKENLKNNPYPQ
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCHHHCCCHHHHHHHHHHCCCCCCH
SLQDQVRQFRSIPPFDSRGWLHEIKVPTLVIAAEDDILTLPAESQQLAQRIPNAQFITIP
HHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEECCCEEECCCCHHHHHHHCCCCEEEEEC
GGHSSPLEHPALVNDAILKFLTSS
CCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATLKIHDVDIYYELYGQGKPLVLIAGYCCDHTFWNAMLHELAEEFQVLIFDNRGIGQTR
CEEEEEEEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCC
DNGDSFTLEAQADDIMAFLEQLGFRNPSILGQSMGGAIAQLLARKHGKKISKLVILNSVA
CCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
KFNTRANQAMESLLNLRKENISFDLLIEAGIPWFFSSEYLAEPKNIATFKENLKNNPYPQ
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCHHHCCCHHHHHHHHHHCCCCCCH
SLQDQVRQFRSIPPFDSRGWLHEIKVPTLVIAAEDDILTLPAESQQLAQRIPNAQFITIP
HHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEECCCEEECCCCHHHHHHHCCCCEEEEEC
GGHSSPLEHPALVNDAILKFLTSS
CCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA