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The map label for this gene is np20 [H]

Identifier: 148358441

GI number: 148358441

Start: 324561

End: 325094

Strand: Direct

Name: np20 [H]

Synonym: LPC_0307

Alternate gene names: 148358441

Gene position: 324561-325094 (Clockwise)

Preceding gene: 148358437

Following gene: 148358447

Centisome position: 9.07

GC content: 37.83

Gene sequence:

>534_bases
ATGATTGGCTGTTGTTTGATCATTTTTCCTTGCAACAGGGATTATGATAAAATAGTGCGCACTAACTATTCGCTTGAAAG
AAGATTAATGAAACATAATTTGTTGGATAAGGCTTATAAACATTGTGTAAACCATGGCTATCGATTTACCGAGCCAAGGG
AGCGTGTCCTCAAAATATTAGTCGATGAGAGAAAGCCACTCGGTGCTTATGACATACTGCAAAGATTATCTATGGAAGTG
GATAACCCCAAGCCACCAACGGTCTACCGGGCTATTCAATTTTGGCATCAAGAGGGATTTATTCATTGCATTGACAGTCT
GAAATCCTATGTCGCCTGTTTACATGGGCATCATGTGGGACAAGCTCAATTTCTTATATGCAATCAGTGTGATTTTGTCA
AAGAATTGGAATGTGTAGTTGATTTTACTTCGGTAACAGAAGCGGCGAATTCCATTCAATTTTCAATTATTAATTGTACG
GTAGAAATCAAAGGCTTGTGTTCTGATTGCAATCTGACTAACCTGAAAAATTAA

Upstream 100 bases:

>100_bases
CATACTGCCTTTCTCAAAAAATGTTATATTGTAACATTTAATTGTTAGATAACAAGAAAAATTAAATAATTTTTAGACAG
TAATTGATTTCTATGAAATA

Downstream 100 bases:

>100_bases
TTCCCGGCAATAATTTTCCTATGAGTTGTAAAATAACAAATTTTTAAATAATGAGACTGATTTTATGCTTTGCATTTTCA
GATAATGCAAAAGCCAATGT

Product: Fur family transporter transcriptional regulator np20

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MIGCCLIIFPCNRDYDKIVRTNYSLERRLMKHNLLDKAYKHCVNHGYRFTEPRERVLKILVDERKPLGAYDILQRLSMEV
DNPKPPTVYRAIQFWHQEGFIHCIDSLKSYVACLHGHHVGQAQFLICNQCDFVKELECVVDFTSVTEAANSIQFSIINCT
VEIKGLCSDCNLTNLKN

Sequences:

>Translated_177_residues
MIGCCLIIFPCNRDYDKIVRTNYSLERRLMKHNLLDKAYKHCVNHGYRFTEPRERVLKILVDERKPLGAYDILQRLSMEV
DNPKPPTVYRAIQFWHQEGFIHCIDSLKSYVACLHGHHVGQAQFLICNQCDFVKELECVVDFTSVTEAANSIQFSIINCT
VEIKGLCSDCNLTNLKN
>Mature_177_residues
MIGCCLIIFPCNRDYDKIVRTNYSLERRLMKHNLLDKAYKHCVNHGYRFTEPRERVLKILVDERKPLGAYDILQRLSMEV
DNPKPPTVYRAIQFWHQEGFIHCIDSLKSYVACLHGHHVGQAQFLICNQCDFVKELECVVDFTSVTEAANSIQFSIINCT
VEIKGLCSDCNLTNLKN

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=140, Percent_Identity=34.2857142857143, Blast_Score=81, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 20499; Mature: 20499

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
6.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGCCLIIFPCNRDYDKIVRTNYSLERRLMKHNLLDKAYKHCVNHGYRFTEPRERVLKIL
CCEEEEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VDERKPLGAYDILQRLSMEVDNPKPPTVYRAIQFWHQEGFIHCIDSLKSYVACLHGHHVG
HHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
QAQFLICNQCDFVKELECVVDFTSVTEAANSIQFSIINCTVEIKGLCSDCNLTNLKN
CEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MIGCCLIIFPCNRDYDKIVRTNYSLERRLMKHNLLDKAYKHCVNHGYRFTEPRERVLKIL
CCEEEEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VDERKPLGAYDILQRLSMEVDNPKPPTVYRAIQFWHQEGFIHCIDSLKSYVACLHGHHVG
HHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
QAQFLICNQCDFVKELECVVDFTSVTEAANSIQFSIINCTVEIKGLCSDCNLTNLKN
CEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]