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The map label for this gene is visC [H]

Identifier: 148358239

GI number: 148358239

Start: 99160

End: 100326

Strand: Direct

Name: visC [H]

Synonym: LPC_0101

Alternate gene names: 148358239

Gene position: 99160-100326 (Clockwise)

Preceding gene: 148358238

Following gene: 148358243

Centisome position: 2.77

GC content: 42.25

Gene sequence:

>1167_bases
ATGAGCCAACATTTTGATGTACTTGTCATTGGAGGCGGGATTGTTGGCTTGACAGCAGCTTTAGCCATGGCCCAACGCCA
TTATACTGTTGCTGTTATCGATGCGGGGACATTGATGGTCAATACAGACAAGAGTGATTTGCGTGTTTATGCCATCAATA
AGGCATCAAAAATGTTATTAAGTGAATTGGGAGTGTGGCAGCACCTCGATGATGCTCGGGTCGCTCCTTATAATAAAATG
CATGTATGGGATGGTGTGAGTGGCGCATATATTGACTTTGATTCTCGCAGTATTGCTGAGCCAAATTTAGGGGCAATTAT
TGAAGAATCAATCTTAAAGCAAGCTCTGTTGCGTCGAATCTCATCAGAGTCCAAAATAAATTTATTTCCTCAAAGTGTAA
TAGATGAGGTGTGCCATTTAGAGCGGAGCATCAAGATCTCCGGCCAAAATACTGCCTGGGAAGGGCAGTTATTGATGATA
GCTGACGGAGCTAACTCTCCTATGCGTCATAAGCTTAAAGTGGATGTAACCACCTGGTCTTATGAGCAGCAAGCGTTGGT
CGCAACCGTAAATAGTGAGAAATCACATCAGAATACTGCTTTTCAAGTGTTTCATCCTGATGGCCCTTTGGCTTTTTTGC
CATTATCTAATCTCAACCAATGTTCTATCGTTTGGTCAACTCATGCCGATAATGCGATGCGATTGAAGTTACTTGATGAT
AATGAATTTAGCCGGGAATTGACTAAGGCATTTGGAGGTCAGCTAGGGCAAATAAAGGTAGCAAGCAATCGCCATCAATT
TCCTTTACAAATGAGACATGTCAAGCAATATGCAGGGCATCGCTGGTTATTGCTTGGTGATGCAGCCCACACTATTCATC
CATTAGCCGGTCTTGGGTTAAATGTTGGCCTGGCTGATGTGAAAAGCTGGTTAACCTGTCTTGAAATGGGTAAAGGTGAA
TTGATATCCAAAAAAGTATTAGGGACATACCAAAGGGAACGCAAGCATTCTGTTGGCAAATTATTTTGCTTATGGAGGGA
TTTAAAAGATTATTTGGAACCTCCGCATCTCCTGTTACCTCATTACGCAGTCTCGGATTGCGGGCATGCAATGAATTTAT
CCCAATTAAACGATTATTTATGCGCCAGGCTAGTGGTTTATAAGTAA

Upstream 100 bases:

>100_bases
TACCGGCATTAAAAAATTTATTAGCACGATATGCGCGTGGTTTTGGCGGAATTACTCCTGATTTGGTTTGTGAAATTGCA
TTAAGCACTGGAGAATTTCA

Downstream 100 bases:

>100_bases
TTTTTCGCCAAAGTAAGGCTTTTTTTCAAAAAAGATATAATGCTTAATTTTTAGTTAATAATTGTTATGTATAATTTTTT
TGCTAACCTAAAAAACTCTC

Product: 2-polyprenyl-6-methoxyphenol hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSQHFDVLVIGGGIVGLTAALAMAQRHYTVAVIDAGTLMVNTDKSDLRVYAINKASKMLLSELGVWQHLDDARVAPYNKM
HVWDGVSGAYIDFDSRSIAEPNLGAIIEESILKQALLRRISSESKINLFPQSVIDEVCHLERSIKISGQNTAWEGQLLMI
ADGANSPMRHKLKVDVTTWSYEQQALVATVNSEKSHQNTAFQVFHPDGPLAFLPLSNLNQCSIVWSTHADNAMRLKLLDD
NEFSRELTKAFGGQLGQIKVASNRHQFPLQMRHVKQYAGHRWLLLGDAAHTIHPLAGLGLNVGLADVKSWLTCLEMGKGE
LISKKVLGTYQRERKHSVGKLFCLWRDLKDYLEPPHLLLPHYAVSDCGHAMNLSQLNDYLCARLVVYK

Sequences:

>Translated_388_residues
MSQHFDVLVIGGGIVGLTAALAMAQRHYTVAVIDAGTLMVNTDKSDLRVYAINKASKMLLSELGVWQHLDDARVAPYNKM
HVWDGVSGAYIDFDSRSIAEPNLGAIIEESILKQALLRRISSESKINLFPQSVIDEVCHLERSIKISGQNTAWEGQLLMI
ADGANSPMRHKLKVDVTTWSYEQQALVATVNSEKSHQNTAFQVFHPDGPLAFLPLSNLNQCSIVWSTHADNAMRLKLLDD
NEFSRELTKAFGGQLGQIKVASNRHQFPLQMRHVKQYAGHRWLLLGDAAHTIHPLAGLGLNVGLADVKSWLTCLEMGKGE
LISKKVLGTYQRERKHSVGKLFCLWRDLKDYLEPPHLLLPHYAVSDCGHAMNLSQLNDYLCARLVVYK
>Mature_387_residues
SQHFDVLVIGGGIVGLTAALAMAQRHYTVAVIDAGTLMVNTDKSDLRVYAINKASKMLLSELGVWQHLDDARVAPYNKMH
VWDGVSGAYIDFDSRSIAEPNLGAIIEESILKQALLRRISSESKINLFPQSVIDEVCHLERSIKISGQNTAWEGQLLMIA
DGANSPMRHKLKVDVTTWSYEQQALVATVNSEKSHQNTAFQVFHPDGPLAFLPLSNLNQCSIVWSTHADNAMRLKLLDDN
EFSRELTKAFGGQLGQIKVASNRHQFPLQMRHVKQYAGHRWLLLGDAAHTIHPLAGLGLNVGLADVKSWLTCLEMGKGEL
ISKKVLGTYQRERKHSVGKLFCLWRDLKDYLEPPHLLLPHYAVSDCGHAMNLSQLNDYLCARLVVYK

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=345, Percent_Identity=31.0144927536232, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI32967307, Length=311, Percent_Identity=30.5466237942122, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1789273, Length=354, Percent_Identity=39.2655367231638, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1786883, Length=340, Percent_Identity=34.4117647058824, Blast_Score=178, Evalue=7e-46,
Organism=Escherichia coli, GI1789274, Length=339, Percent_Identity=30.3834808259587, Blast_Score=152, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI25146631, Length=382, Percent_Identity=29.8429319371728, Blast_Score=141, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6321694, Length=424, Percent_Identity=26.8867924528302, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920760, Length=386, Percent_Identity=30.3108808290155, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 43297; Mature: 43166

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQHFDVLVIGGGIVGLTAALAMAQRHYTVAVIDAGTLMVNTDKSDLRVYAINKASKMLL
CCCCEEEEEECCCHHHHHHHHHHHHCCEEEEEEECCEEEEECCCCCEEEEEECHHHHHHH
SELGVWQHLDDARVAPYNKMHVWDGVSGAYIDFDSRSIAEPNLGAIIEESILKQALLRRI
HHCCHHHCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
SSESKINLFPQSVIDEVCHLERSIKISGQNTAWEGQLLMIADGANSPMRHKLKVDVTTWS
CCCCEEEECHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCCCCCEEEEEEEEEEC
YEQQALVATVNSEKSHQNTAFQVFHPDGPLAFLPLSNLNQCSIVWSTHADNAMRLKLLDD
CCCCEEEEEECCCCCCCCCEEEEECCCCCEEEEECCCCCCEEEEEEECCCCEEEEEEECC
NEFSRELTKAFGGQLGQIKVASNRHQFPLQMRHVKQYAGHRWLLLGDAAHTIHPLAGLGL
CHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCC
NVGLADVKSWLTCLEMGKGELISKKVLGTYQRERKHSVGKLFCLWRDLKDYLEPPHLLLP
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECC
HYAVSDCGHAMNLSQLNDYLCARLVVYK
CHHHHHCCCCCCHHHHHHHHHHEEEECC
>Mature Secondary Structure 
SQHFDVLVIGGGIVGLTAALAMAQRHYTVAVIDAGTLMVNTDKSDLRVYAINKASKMLL
CCCEEEEEECCCHHHHHHHHHHHHCCEEEEEEECCEEEEECCCCCEEEEEECHHHHHHH
SELGVWQHLDDARVAPYNKMHVWDGVSGAYIDFDSRSIAEPNLGAIIEESILKQALLRRI
HHCCHHHCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
SSESKINLFPQSVIDEVCHLERSIKISGQNTAWEGQLLMIADGANSPMRHKLKVDVTTWS
CCCCEEEECHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCCCCCEEEEEEEEEEC
YEQQALVATVNSEKSHQNTAFQVFHPDGPLAFLPLSNLNQCSIVWSTHADNAMRLKLLDD
CCCCEEEEEECCCCCCCCCEEEEECCCCCEEEEECCCCCCEEEEEEECCCCEEEEEEECC
NEFSRELTKAFGGQLGQIKVASNRHQFPLQMRHVKQYAGHRWLLLGDAAHTIHPLAGLGL
CHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCC
NVGLADVKSWLTCLEMGKGELISKKVLGTYQRERKHSVGKLFCLWRDLKDYLEPPHLLLP
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECC
HYAVSDCGHAMNLSQLNDYLCARLVVYK
CHHHHHCCCCCCHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]