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The map label for this gene is yciR [C]

Identifier: 148358233

GI number: 148358233

Start: 92152

End: 93765

Strand: Direct

Name: yciR [C]

Synonym: LPC_0095

Alternate gene names: 148358233

Gene position: 92152-93765 (Clockwise)

Preceding gene: 148358232

Following gene: 148358236

Centisome position: 2.58

GC content: 36.49

Gene sequence:

>1614_bases
ATGAATATTAAATCTAATTTGGCATATAGCTCTGTTATCCTGAAAGGTCATGTCAATCGATATGCCTTTTTAGGATTGCT
TATTTCTGTTGGCAGTATCTTGATTGCAAGTTGTATCGTTTCCTATCAATTGACTGGATCTGTGAGTTTAGGCGGGTTTA
TTCAGGCTCAAAGAACTAACCCGGCAATTTGGATCCTGGATTTAACACCTTTTATGTTTGTGTATTGGGGGCAAGCGTTT
TGTTATGGATTGGTTAACAAAGCGGAGAGTTTGCTGGTTGATAAAACCAAAGAGCTTTTAAATATCAGTGGAAATCTGGA
ATTAAAGCTCAAATATGAAAGTAATCACGATAGCTTGACCAATTTGCCTAACAACCGCTTGTTAAATGAAAAAATACGGC
TCGCCATCGAACAATTGGGCTTACAGGGTGAATTAGCTGTTATTGTGATAAAAATTAATGATCTTAATTATAATTTCAGC
TCATTTAATGCCAATAATATCGTAAAGCAATTTGCTGAAAAATTAAAATCGATTTTGATTGATCCCTACATGCTAAAAGC
TTCTCTTGGAATTAATATGGTTGCAAGATTGCAAAGTGATGAATTTGCCATATTGATGCCGAGACTTAAAAAAGATTTGG
ATATTAATGAGCTATTAATCCATCTTCTTACCTTGCTGAATAATAACCTGATGGTGGATGGAATTAGTATCAATGTGACA
TCTACCGTTGGTGCTGCTATCTATCCTGCCCATGGAGAGGAAGACGATGTTTTAGTAAATCATGCCATTATTGCAGTTTA
CCAGGCACGAAAAGAAAACAAATCCTATGCAATTTACAGCCCTGAAATGGAAGAAGACCTTATACAGAATAGGATTGTGA
TGAATGAACTGCAGCGCTCCATTGAAAACAAAGATTTGAAAATTTATTACCAGCCAATAGTTGAACTGGCTAATGGCCAA
ATTGTAGGTGCCGAGTCATCAGCTCGCTTTGAACATCCTGAATTGGGTTTATTAAGTGCAGAAAAATTCATGCCTTTAAT
CGAGGGAACCAGTTTAATTCATAATTTGACAACTCTTATGCTTAAGGAAGTCATAAAGCAATTAGCCGCCTGGCATGATG
CTGGACATAAAATTTTTGTCTCTGTAAATCTGTCAGTGCACCATGAGTTGCCTGAATTAATAGAGAAATTATTAAATGAT
TATGAGATTGCCCCGGAATTCTTGAAACTTGAATTTACCGAAAGGGCTTGTTTAACTGAGCAGATGGTTACCAAAGAAGT
GTTTGACCGATTATCAACCATGGGCATCAAATTATGCATTGATGATTTTTGCAGTGAGAACTCTTCCTTCATTCATTTGA
CTAATTTTCCTATCGAAAACATTAAAATTGAGAAATCATTCGTACTGAAAATTGCAAAAGACGCAAAGAAAGCCAAAATT
GTAGAGGCTATAGTAAAACTAGCCCAAACATTAGGGTGGGAACCCCTGGCAGATGGCATCGCTGATCAAAATGCATTGGA
AAAATTAAGAGACTTAGGCTGCTTGTATGGCCAGGGATTATATTTTTCTCGAGCGGTCAATGTGGCTGAATTTACATCAT
TGCTAAAGAAATGA

Upstream 100 bases:

>100_bases
CCATTTATTCAGTTTTTTGTAGAGCATTGAAGTCGCTGTAGAAGGGATGAGGTATTAAAAATTAGCCTGTTGACAGGCAT
AAGGGAATTACTGTTACTCC

Downstream 100 bases:

>100_bases
ATCTGGCTTTAAATCACTTACTATTCGTTTTCACGCTTTGATTCACATGGAATACGAATCACAACGCTGACAGCTATGGC
CGCACTGATATTAAAATTTG

Product: diguanylate cyclase/phosphodiesterase domain 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MNIKSNLAYSSVILKGHVNRYAFLGLLISVGSILIASCIVSYQLTGSVSLGGFIQAQRTNPAIWILDLTPFMFVYWGQAF
CYGLVNKAESLLVDKTKELLNISGNLELKLKYESNHDSLTNLPNNRLLNEKIRLAIEQLGLQGELAVIVIKINDLNYNFS
SFNANNIVKQFAEKLKSILIDPYMLKASLGINMVARLQSDEFAILMPRLKKDLDINELLIHLLTLLNNNLMVDGISINVT
STVGAAIYPAHGEEDDVLVNHAIIAVYQARKENKSYAIYSPEMEEDLIQNRIVMNELQRSIENKDLKIYYQPIVELANGQ
IVGAESSARFEHPELGLLSAEKFMPLIEGTSLIHNLTTLMLKEVIKQLAAWHDAGHKIFVSVNLSVHHELPELIEKLLND
YEIAPEFLKLEFTERACLTEQMVTKEVFDRLSTMGIKLCIDDFCSENSSFIHLTNFPIENIKIEKSFVLKIAKDAKKAKI
VEAIVKLAQTLGWEPLADGIADQNALEKLRDLGCLYGQGLYFSRAVNVAEFTSLLKK

Sequences:

>Translated_537_residues
MNIKSNLAYSSVILKGHVNRYAFLGLLISVGSILIASCIVSYQLTGSVSLGGFIQAQRTNPAIWILDLTPFMFVYWGQAF
CYGLVNKAESLLVDKTKELLNISGNLELKLKYESNHDSLTNLPNNRLLNEKIRLAIEQLGLQGELAVIVIKINDLNYNFS
SFNANNIVKQFAEKLKSILIDPYMLKASLGINMVARLQSDEFAILMPRLKKDLDINELLIHLLTLLNNNLMVDGISINVT
STVGAAIYPAHGEEDDVLVNHAIIAVYQARKENKSYAIYSPEMEEDLIQNRIVMNELQRSIENKDLKIYYQPIVELANGQ
IVGAESSARFEHPELGLLSAEKFMPLIEGTSLIHNLTTLMLKEVIKQLAAWHDAGHKIFVSVNLSVHHELPELIEKLLND
YEIAPEFLKLEFTERACLTEQMVTKEVFDRLSTMGIKLCIDDFCSENSSFIHLTNFPIENIKIEKSFVLKIAKDAKKAKI
VEAIVKLAQTLGWEPLADGIADQNALEKLRDLGCLYGQGLYFSRAVNVAEFTSLLKK
>Mature_537_residues
MNIKSNLAYSSVILKGHVNRYAFLGLLISVGSILIASCIVSYQLTGSVSLGGFIQAQRTNPAIWILDLTPFMFVYWGQAF
CYGLVNKAESLLVDKTKELLNISGNLELKLKYESNHDSLTNLPNNRLLNEKIRLAIEQLGLQGELAVIVIKINDLNYNFS
SFNANNIVKQFAEKLKSILIDPYMLKASLGINMVARLQSDEFAILMPRLKKDLDINELLIHLLTLLNNNLMVDGISINVT
STVGAAIYPAHGEEDDVLVNHAIIAVYQARKENKSYAIYSPEMEEDLIQNRIVMNELQRSIENKDLKIYYQPIVELANGQ
IVGAESSARFEHPELGLLSAEKFMPLIEGTSLIHNLTTLMLKEVIKQLAAWHDAGHKIFVSVNLSVHHELPELIEKLLND
YEIAPEFLKLEFTERACLTEQMVTKEVFDRLSTMGIKLCIDDFCSENSSFIHLTNFPIENIKIEKSFVLKIAKDAKKAKI
VEAIVKLAQTLGWEPLADGIADQNALEKLRDLGCLYGQGLYFSRAVNVAEFTSLLKK

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=445, Percent_Identity=25.6179775280899, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI87081921, Length=438, Percent_Identity=27.3972602739726, Blast_Score=145, Evalue=9e-36,
Organism=Escherichia coli, GI87081743, Length=242, Percent_Identity=33.8842975206612, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI226510982, Length=438, Percent_Identity=24.2009132420091, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1790496, Length=247, Percent_Identity=27.9352226720648, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786507, Length=247, Percent_Identity=29.9595141700405, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI87081845, Length=247, Percent_Identity=28.7449392712551, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87081980, Length=244, Percent_Identity=28.2786885245902, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788502, Length=249, Percent_Identity=27.710843373494, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082096, Length=245, Percent_Identity=27.3469387755102, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787055, Length=289, Percent_Identity=21.7993079584775, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788849, Length=241, Percent_Identity=24.0663900414938, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 60290; Mature: 60290

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKSNLAYSSVILKGHVNRYAFLGLLISVGSILIASCIVSYQLTGSVSLGGFIQAQRTN
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEECCEEEEECCC
PAIWILDLTPFMFVYWGQAFCYGLVNKAESLLVDKTKELLNISGNLELKLKYESNHDSLT
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
NLPNNRLLNEKIRLAIEQLGLQGELAVIVIKINDLNYNFSSFNANNIVKQFAEKLKSILI
CCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHC
DPYMLKASLGINMVARLQSDEFAILMPRLKKDLDINELLIHLLTLLNNNLMVDGISINVT
CCHHHHHHCCCCEEEEECCCCEEEEEHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEEEEE
STVGAAIYPAHGEEDDVLVNHAIIAVYQARKENKSYAIYSPEMEEDLIQNRIVMNELQRS
CCCCCEEECCCCCCCCEEHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
IENKDLKIYYQPIVELANGQIVGAESSARFEHPELGLLSAEKFMPLIEGTSLIHNLTTLM
HCCCCEEEEEEHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LKEVIKQLAAWHDAGHKIFVSVNLSVHHELPELIEKLLNDYEIAPEFLKLEFTERACLTE
HHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHCCCHHHEEEHHHHHHHHH
QMVTKEVFDRLSTMGIKLCIDDFCSENSSFIHLTNFPIENIKIEKSFVLKIAKDAKKAKI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHH
VEAIVKLAQTLGWEPLADGIADQNALEKLRDLGCLYGQGLYFSRAVNVAEFTSLLKK
HHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MNIKSNLAYSSVILKGHVNRYAFLGLLISVGSILIASCIVSYQLTGSVSLGGFIQAQRTN
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEECCEEEEECCC
PAIWILDLTPFMFVYWGQAFCYGLVNKAESLLVDKTKELLNISGNLELKLKYESNHDSLT
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
NLPNNRLLNEKIRLAIEQLGLQGELAVIVIKINDLNYNFSSFNANNIVKQFAEKLKSILI
CCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHC
DPYMLKASLGINMVARLQSDEFAILMPRLKKDLDINELLIHLLTLLNNNLMVDGISINVT
CCHHHHHHCCCCEEEEECCCCEEEEEHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEEEEE
STVGAAIYPAHGEEDDVLVNHAIIAVYQARKENKSYAIYSPEMEEDLIQNRIVMNELQRS
CCCCCEEECCCCCCCCEEHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
IENKDLKIYYQPIVELANGQIVGAESSARFEHPELGLLSAEKFMPLIEGTSLIHNLTTLM
HCCCCEEEEEEHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LKEVIKQLAAWHDAGHKIFVSVNLSVHHELPELIEKLLNDYEIAPEFLKLEFTERACLTE
HHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHCCCHHHEEEHHHHHHHHH
QMVTKEVFDRLSTMGIKLCIDDFCSENSSFIHLTNFPIENIKIEKSFVLKIAKDAKKAKI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHH
VEAIVKLAQTLGWEPLADGIADQNALEKLRDLGCLYGQGLYFSRAVNVAEFTSLLKK
HHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]