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The map label for this gene is intZ [H]

Identifier: 148358224

GI number: 148358224

Start: 82602

End: 83825

Strand: Direct

Name: intZ [H]

Synonym: LPC_0085

Alternate gene names: 148358224

Gene position: 82602-83825 (Clockwise)

Preceding gene: 148358223

Following gene: 148358225

Centisome position: 2.31

GC content: 40.85

Gene sequence:

>1224_bases
ATGAAAAATTTTACAGATACTTATATTAGAAATTTAAAGGCTAAAGAAAAGCGTTATGAAGAATTTGAAGGGGGTGGATT
TGGTATCCGAATCACACCAAACAACGTCAAAACATGGATCTATCGTTACAAAATCAATGGTGTGACTACAAAGTTTACCT
TAGGGCATTACCCTGCGATGAGTTTGTCGAATGCCAAAAGACGATTCCTTGAATTGTCACAAATGCGCAGAGAAGGGGTT
GATCCCAAAACGGTGATACAAGCTCAAGAAGAACAGGACAATAATACAGTCGATAAATTGGCGCTGAACTGGTATACAAA
TTACATCGAAAAACATGTAAAGCGTCCTTTGGTAATCAAACGCCAAATTGATAATGATATCATTCCCTTGTTAGGCAAGA
AAAAACTGGATGACGTGCAAACCAAAGATATTAGCGACGCATTGGATACCATCGTCAAGCGAGGCGCAAGAATACTTGCC
AATCGCACTTTAAGTTCCATTAAGCAAATGTTTAACTATGCAGTTAGCCGAGGGTATACGCAGTTCAATCCTGCTAGTAA
TATTCGGTCACGAGATATTGGCGGCATTGAAAAACCGAAAGAGCGGGTATTAACGCTTGAAGAAATCAAAGCTTTGTGGC
TGTTTTTAGACAGCGATCTAACTCAAATGTCTACACAAACCCGTATAGCGATTAAGCTCTTGCTACTCACCGGTGTGAGA
ACAGTTGAGTTGCGCCTTGCCAGTTGGCATGAAATTGATTTTGAGGCCTCTTTATGGACGATCCCCGCTTTGCACTCCAA
AGCCAGCATCATTCATAAAGTCCACCTGAGCAAGTTAGCCAAATCACTCTTTTTGCAACTCAAGCCCTTAAGCCATTCTG
ATTACGTACTCACTGGTGTCGATGGATTTCATCCTATAACGGAGAATGCTCTTCCAAGAGCGATAAAACGCATTCAAGAA
AAGCTTGGCATACCAGATTGGACTGCCCACGATTTACGTCGTACTTTTGCTACCCAGCTTGGAGAAACTCTTCAAATTGA
TCCTGTGGTGATAGAAAAATGCCTTGGCCATAAAATGCCACGGATTATGGCAACTTATAACCGCAATGAAATGTTACCTC
AGAGACGAGAAGCTCTCGAGCGTTGGGCGGTATGTATTGAAAATATGATGCAAGATAATGTGGTATATATTAACAAACTA
CTCCAAAACGAAAGATCTTTGTAA

Upstream 100 bases:

>100_bases
ACAAATATCCATTTCAAATATTTACATTGAATATCATCCCAGCACATAATTAAGTGTACCCCAATGTGTACCCTATTCGA
CCTGATGACATGAGATTTTG

Downstream 100 bases:

>100_bases
AACAAATTTGTCATTTTTATTTGCGACTGGAAAAAATAATAACAATAAGTTATCATATAAGATAACAAAGGATTTAATAA
TAAATGTCTTGGATTGTTGA

Product: integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKNFTDTYIRNLKAKEKRYEEFEGGGFGIRITPNNVKTWIYRYKINGVTTKFTLGHYPAMSLSNAKRRFLELSQMRREGV
DPKTVIQAQEEQDNNTVDKLALNWYTNYIEKHVKRPLVIKRQIDNDIIPLLGKKKLDDVQTKDISDALDTIVKRGARILA
NRTLSSIKQMFNYAVSRGYTQFNPASNIRSRDIGGIEKPKERVLTLEEIKALWLFLDSDLTQMSTQTRIAIKLLLLTGVR
TVELRLASWHEIDFEASLWTIPALHSKASIIHKVHLSKLAKSLFLQLKPLSHSDYVLTGVDGFHPITENALPRAIKRIQE
KLGIPDWTAHDLRRTFATQLGETLQIDPVVIEKCLGHKMPRIMATYNRNEMLPQRREALERWAVCIENMMQDNVVYINKL
LQNERSL

Sequences:

>Translated_407_residues
MKNFTDTYIRNLKAKEKRYEEFEGGGFGIRITPNNVKTWIYRYKINGVTTKFTLGHYPAMSLSNAKRRFLELSQMRREGV
DPKTVIQAQEEQDNNTVDKLALNWYTNYIEKHVKRPLVIKRQIDNDIIPLLGKKKLDDVQTKDISDALDTIVKRGARILA
NRTLSSIKQMFNYAVSRGYTQFNPASNIRSRDIGGIEKPKERVLTLEEIKALWLFLDSDLTQMSTQTRIAIKLLLLTGVR
TVELRLASWHEIDFEASLWTIPALHSKASIIHKVHLSKLAKSLFLQLKPLSHSDYVLTGVDGFHPITENALPRAIKRIQE
KLGIPDWTAHDLRRTFATQLGETLQIDPVVIEKCLGHKMPRIMATYNRNEMLPQRREALERWAVCIENMMQDNVVYINKL
LQNERSL
>Mature_407_residues
MKNFTDTYIRNLKAKEKRYEEFEGGGFGIRITPNNVKTWIYRYKINGVTTKFTLGHYPAMSLSNAKRRFLELSQMRREGV
DPKTVIQAQEEQDNNTVDKLALNWYTNYIEKHVKRPLVIKRQIDNDIIPLLGKKKLDDVQTKDISDALDTIVKRGARILA
NRTLSSIKQMFNYAVSRGYTQFNPASNIRSRDIGGIEKPKERVLTLEEIKALWLFLDSDLTQMSTQTRIAIKLLLLTGVR
TVELRLASWHEIDFEASLWTIPALHSKASIIHKVHLSKLAKSLFLQLKPLSHSDYVLTGVDGFHPITENALPRAIKRIQE
KLGIPDWTAHDLRRTFATQLGETLQIDPVVIEKCLGHKMPRIMATYNRNEMLPQRREALERWAVCIENMMQDNVVYINKL
LQNERSL

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=383, Percent_Identity=29.242819843342, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1788690, Length=382, Percent_Identity=28.7958115183246, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788974, Length=408, Percent_Identity=28.4313725490196, Blast_Score=132, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 47081; Mature: 47081

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFTDTYIRNLKAKEKRYEEFEGGGFGIRITPNNVKTWIYRYKINGVTTKFTLGHYPAM
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEECCEEEEEEECCCCCC
SLSNAKRRFLELSQMRREGVDPKTVIQAQEEQDNNTVDKLALNWYTNYIEKHVKRPLVIK
HHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEH
RQIDNDIIPLLGKKKLDDVQTKDISDALDTIVKRGARILANRTLSSIKQMFNYAVSRGYT
HHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QFNPASNIRSRDIGGIEKPKERVLTLEEIKALWLFLDSDLTQMSTQTRIAIKLLLLTGVR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCE
TVELRLASWHEIDFEASLWTIPALHSKASIIHKVHLSKLAKSLFLQLKPLSHSDYVLTGV
EEEEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEECC
DGFHPITENALPRAIKRIQEKLGIPDWTAHDLRRTFATQLGETLQIDPVVIEKCLGHKMP
CCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEECCHHHHHHHHCCCCC
RIMATYNRNEMLPQRREALERWAVCIENMMQDNVVYINKLLQNERSL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNFTDTYIRNLKAKEKRYEEFEGGGFGIRITPNNVKTWIYRYKINGVTTKFTLGHYPAM
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEECCEEEEEEECCCCCC
SLSNAKRRFLELSQMRREGVDPKTVIQAQEEQDNNTVDKLALNWYTNYIEKHVKRPLVIK
HHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEH
RQIDNDIIPLLGKKKLDDVQTKDISDALDTIVKRGARILANRTLSSIKQMFNYAVSRGYT
HHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QFNPASNIRSRDIGGIEKPKERVLTLEEIKALWLFLDSDLTQMSTQTRIAIKLLLLTGVR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCE
TVELRLASWHEIDFEASLWTIPALHSKASIIHKVHLSKLAKSLFLQLKPLSHSDYVLTGV
EEEEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEECC
DGFHPITENALPRAIKRIQEKLGIPDWTAHDLRRTFATQLGETLQIDPVVIEKCLGHKMP
CCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEECCHHHHHHHHCCCCC
RIMATYNRNEMLPQRREALERWAVCIENMMQDNVVYINKLLQNERSL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]