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The map label for this gene is tpr1B18

Identifier: 148285081

GI number: 148285081

Start: 1931709

End: 1932848

Strand: Direct

Name: tpr1B18

Synonym: OTBS_2002

Alternate gene names: NA

Gene position: 1931709-1932848 (Clockwise)

Preceding gene: 148285080

Following gene: 148285083

Centisome position: 90.82

GC content: 28.33

Gene sequence:

>1140_bases
ATGAAAAACGCGTGTAAAAAATTAGCCATTATTTTATCATTAATATTATTAAATACAGCAGCTGTTGCAGCAGAGCAAAG
CATACAACAAGATTTAATCTATGATAAAGATATTCTAGCAGAAGAATATTTTAATATTGGAAGCTCTTTCTTGAGATTAA
AAAAATATCATGAAGCAATTAAAAATTATGATATTGCTATTAAGTATGATCCAAGTTATGCGTCAGCATATAATAGCAAA
GGAATTGCTTTAAATAATCTAGAAAAGCCAAAAGAAGCTATAGAAAATTTCGATTTAGCTATTAAATACAATCCCCATTT
TGCAGAAGCATATAATAACAAGGCTGTATCATATGGAAAGTTAGGAAAAAATAAAGAAGCTATAGTACTTTGTGATCTTG
CTATTAAATATAAACCTAACTATGTAACTGCTTATAATACAAAAGGAGCTTCTTTAAATGACCTAGGAGAGTATGAAGAA
GCAATGGAAAACTTTGATATTGCTATCAGGTATAACTCCAGTTATCCAGAAGCTTATTATAACAAAGGCATAGCTTTAAT
GAATTTAGGTGACATTCAAAATGCAATCGAAAACTATGATATGGCTATTAAATATAGACCAAATTATGCAGAAGCTTATA
TTAATAAAGGTTTAACTTTAGCATTTTTAGGCCAATTGCAGAATGCAATAGAACATTTTGATTTAGCTATTAAATACGAT
CCTAGTTGTGTGAAATCACACTGTAATAAGGGTTATGTATTAAGCTTATTAAAGAGATATTCGGAAGCAGTAGAAAGCTG
TAACTTAGCTATTAAATATGATCCAAATTGTGCGGATATTTATTATAACAAAGGAATGATTTTTGAGAAATTAGGAAAAC
ATCAAGAAGCTGTAGAAAATTTTGATATTGCTATTAAGTATAACCCTAATTTTGCTGAAAATTATCTTGAAAAAGGAATT
TCATTAGTAAGTTTAGGACAGTACTCAAAGGCTAAGGAGAATTTTAACTTAGCTATTAAATATATGCCTAATCTTATAGC
AGAATATGAAGCAACAATTAAAAGGTTAACAGAATTCGAGAATTTTACTATTGCAAAAGACTATGAGCAAAAACTACAGA
TTTTGAAAAAATACTCTTGA

Upstream 100 bases:

>100_bases
AATACAGAATGAATTTAATAATACGTCTAATTCAGCAGTTATTTTGACTGGTAAACAAGCAATAAAAAATTTAAATGGTA
ATAAATGATTAGTAATTAAT

Downstream 100 bases:

>100_bases
GATAGATGAATTTTCAGAATCAAGGCAATTTCACAAGGGGATCGCAGTTATTTGCCCATAAGTTTAAGAATGTTTGGGCA
AGGTAGTACCAATGTTTTTA

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKNACKKLAIILSLILLNTAAVAAEQSIQQDLIYDKDILAEEYFNIGSSFLRLKKYHEAIKNYDIAIKYDPSYASAYNSK
GIALNNLEKPKEAIENFDLAIKYNPHFAEAYNNKAVSYGKLGKNKEAIVLCDLAIKYKPNYVTAYNTKGASLNDLGEYEE
AMENFDIAIRYNSSYPEAYYNKGIALMNLGDIQNAIENYDMAIKYRPNYAEAYINKGLTLAFLGQLQNAIEHFDLAIKYD
PSCVKSHCNKGYVLSLLKRYSEAVESCNLAIKYDPNCADIYYNKGMIFEKLGKHQEAVENFDIAIKYNPNFAENYLEKGI
SLVSLGQYSKAKENFNLAIKYMPNLIAEYEATIKRLTEFENFTIAKDYEQKLQILKKYS

Sequences:

>Translated_379_residues
MKNACKKLAIILSLILLNTAAVAAEQSIQQDLIYDKDILAEEYFNIGSSFLRLKKYHEAIKNYDIAIKYDPSYASAYNSK
GIALNNLEKPKEAIENFDLAIKYNPHFAEAYNNKAVSYGKLGKNKEAIVLCDLAIKYKPNYVTAYNTKGASLNDLGEYEE
AMENFDIAIRYNSSYPEAYYNKGIALMNLGDIQNAIENYDMAIKYRPNYAEAYINKGLTLAFLGQLQNAIEHFDLAIKYD
PSCVKSHCNKGYVLSLLKRYSEAVESCNLAIKYDPNCADIYYNKGMIFEKLGKHQEAVENFDIAIKYNPNFAENYLEKGI
SLVSLGQYSKAKENFNLAIKYMPNLIAEYEATIKRLTEFENFTIAKDYEQKLQILKKYS
>Mature_379_residues
MKNACKKLAIILSLILLNTAAVAAEQSIQQDLIYDKDILAEEYFNIGSSFLRLKKYHEAIKNYDIAIKYDPSYASAYNSK
GIALNNLEKPKEAIENFDLAIKYNPHFAEAYNNKAVSYGKLGKNKEAIVLCDLAIKYKPNYVTAYNTKGASLNDLGEYEE
AMENFDIAIRYNSSYPEAYYNKGIALMNLGDIQNAIENYDMAIKYRPNYAEAYINKGLTLAFLGQLQNAIEHFDLAIKYD
PSCVKSHCNKGYVLSLLKRYSEAVESCNLAIKYDPNCADIYYNKGMIFEKLGKHQEAVENFDIAIKYNPNFAENYLEKGI
SLVSLGQYSKAKENFNLAIKYMPNLIAEYEATIKRLTEFENFTIAKDYEQKLQILKKYS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=246, Percent_Identity=30.0813008130081, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI32307150, Length=246, Percent_Identity=30.0813008130081, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI310123097, Length=317, Percent_Identity=25.8675078864353, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI310110582, Length=317, Percent_Identity=25.8675078864353, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310131789, Length=317, Percent_Identity=25.8675078864353, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI83415184, Length=319, Percent_Identity=24.7648902821317, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI301336134, Length=319, Percent_Identity=24.7648902821317, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI170784867, Length=243, Percent_Identity=27.5720164609054, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI118766330, Length=285, Percent_Identity=25.2631578947368, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI118766328, Length=285, Percent_Identity=25.2631578947368, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI221219056, Length=288, Percent_Identity=23.6111111111111, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI262206280, Length=288, Percent_Identity=23.6111111111111, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI22749211, Length=342, Percent_Identity=24.8538011695906, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI296531396, Length=189, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI224028289, Length=331, Percent_Identity=25.9818731117825, Blast_Score=65, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI115532692, Length=338, Percent_Identity=25.7396449704142, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI115532690, Length=355, Percent_Identity=25.6338028169014, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI25147174, Length=259, Percent_Identity=22.3938223938224, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319387, Length=202, Percent_Identity=27.2277227722772, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17647755, Length=246, Percent_Identity=29.2682926829268, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585827, Length=246, Percent_Identity=29.2682926829268, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585829, Length=246, Percent_Identity=29.2682926829268, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19920486, Length=319, Percent_Identity=24.4514106583072, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI161076610, Length=319, Percent_Identity=24.4514106583072, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647123, Length=285, Percent_Identity=24.9122807017544, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24656717, Length=197, Percent_Identity=30.9644670050761, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI18110006, Length=197, Percent_Identity=30.9644670050761, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 43234; Mature: 43234

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNACKKLAIILSLILLNTAAVAAEQSIQQDLIYDKDILAEEYFNIGSSFLRLKKYHEAI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
KNYDIAIKYDPSYASAYNSKGIALNNLEKPKEAIENFDLAIKYNPHFAEAYNNKAVSYGK
HCCCEEEEECCCHHHHCCCCCCEECCCCCHHHHHCCCCEEEEECCCHHHHHCCCCEEECC
LGKNKEAIVLCDLAIKYKPNYVTAYNTKGASLNDLGEYEEAMENFDIAIRYNSSYPEAYY
CCCCCCEEEEEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHH
NKGIALMNLGDIQNAIENYDMAIKYRPNYAEAYINKGLTLAFLGQLQNAIEHFDLAIKYD
HCCEEEEECHHHHHHHHCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEEC
PSCVKSHCNKGYVLSLLKRYSEAVESCNLAIKYDPNCADIYYNKGMIFEKLGKHQEAVEN
CHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCHHHHHHCCHHHHHCC
FDIAIKYNPNFAENYLEKGISLVSLGQYSKAKENFNLAIKYMPNLIAEYEATIKRLTEFE
CEEEEEECCCHHHHHHHCCCCEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHC
NFTIAKDYEQKLQILKKYS
CCEEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNACKKLAIILSLILLNTAAVAAEQSIQQDLIYDKDILAEEYFNIGSSFLRLKKYHEAI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
KNYDIAIKYDPSYASAYNSKGIALNNLEKPKEAIENFDLAIKYNPHFAEAYNNKAVSYGK
HCCCEEEEECCCHHHHCCCCCCEECCCCCHHHHHCCCCEEEEECCCHHHHHCCCCEEECC
LGKNKEAIVLCDLAIKYKPNYVTAYNTKGASLNDLGEYEEAMENFDIAIRYNSSYPEAYY
CCCCCCEEEEEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHH
NKGIALMNLGDIQNAIENYDMAIKYRPNYAEAYINKGLTLAFLGQLQNAIEHFDLAIKYD
HCCEEEEECHHHHHHHHCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEEC
PSCVKSHCNKGYVLSLLKRYSEAVESCNLAIKYDPNCADIYYNKGMIFEKLGKHQEAVEN
CHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCHHHHHHCCHHHHHCC
FDIAIKYNPNFAENYLEKGISLVSLGQYSKAKENFNLAIKYMPNLIAEYEATIKRLTEFE
CEEEEEECCCHHHHHHHCCCCEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHC
NFTIAKDYEQKLQILKKYS
CCEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]