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The map label for this gene is asd [H]

Identifier: 148284977

GI number: 148284977

Start: 1737280

End: 1738329

Strand: Direct

Name: asd [H]

Synonym: OTBS_1798

Alternate gene names: 148284977

Gene position: 1737280-1738329 (Clockwise)

Preceding gene: 148284976

Following gene: 148284981

Centisome position: 81.68

GC content: 29.24

Gene sequence:

>1050_bases
ATGATAAATGTGATGAATAATAAAATTAACATAGCAGTTATAGGTGCTACAGGTAATGTAGGTAGGTTATTAATTGATAT
TTTATATGAAAGGCAACTGCCAATAAGACATCTTTATTGTATATCTAATAATTTAATTGGACATAACATAAGTTTTGGAC
AACAAAATATTGTTACTCAGTCTATAAAAAATTTTGATTTTAGAGGTATTAATATAGTATTTTCTTGCGTTAATGCTCAA
GTTGCAAAATCTATTGTTCCAAAGATAGTATCAGCAGGGGCAAAAGTAATTGATAAGTCATCTTATTTTAGACTGAAGAG
TGATATTCCTTTAGTTATACCAGAAATAAATATTGATACTATTACAACTGATTCGCGTATTATATCTAGCCCGAATTGTT
GTGTAGTCCCATTAATATTAGTTCTAAAGCCATTAGATGATGTTGCTAAAATTAAAAAATTAGTTATTGCAACATATCAA
TCTACTTCAGGGGCAGGGAAAGATGCAATAGAAGAATTAGATATGCAAACTAGAAATAGATATTTAGAACAATCGGAAAC
ATTAACTCCGCAAATTTTTCCTAAGCAGATTGCTTTTAATATTATACCTCAGATAGGAATGATCATGGAGAATGGTAGGT
GTGATGAAGAAGATAAAATAATTCGCGAAATACAAAAAATTATTGGTCGTCAAATTGCTATATCAATTACCTGTGTAAGA
GTGCCAACATTTGTTAGCCATGCTTTTGCAGTTAATGTTGAATTTGAGTATAATTTAAGCGTGAAAGATGCAGAATCATT
GCTTGTAAAACTTAATGGTATTAAATTAATCAGTAATGTCAAGAATAGTATGAGTAATATAAGCTCAGATATTGTTACTC
CAGTTGATGTTACTGGGAAAAATGATGTTTTTGTTAGCAGAATAAGAAAAGAGAAAAATATAAAGAATAGTTTGAGCTTA
TGGATAAGTACTGATAATTTGCGAAAAGGATCAGCACTGAATGCAGTACAAATTGCTGAAAATATTCTTTTGCAGCAAAA
ATTAATATGA

Upstream 100 bases:

>100_bases
TTCCACATTTTCATACTCATATCATTTCAAATCAGAAAATTGAATTAAATTAATATATTTTAAACGTATTATTCAAAATA
CGCTCTAGTATGTTTGGTAT

Downstream 100 bases:

>100_bases
TTATAAAAGTTAAGATAGTTATAAACTTTGCTATTTAAAATCATAGCAAAACAACTATAAGAGATTTATAATTAAAAATA
TATGAATATTAGATCAAATC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MINVMNNKINIAVIGATGNVGRLLIDILYERQLPIRHLYCISNNLIGHNISFGQQNIVTQSIKNFDFRGINIVFSCVNAQ
VAKSIVPKIVSAGAKVIDKSSYFRLKSDIPLVIPEINIDTITTDSRIISSPNCCVVPLILVLKPLDDVAKIKKLVIATYQ
STSGAGKDAIEELDMQTRNRYLEQSETLTPQIFPKQIAFNIIPQIGMIMENGRCDEEDKIIREIQKIIGRQIAISITCVR
VPTFVSHAFAVNVEFEYNLSVKDAESLLVKLNGIKLISNVKNSMSNISSDIVTPVDVTGKNDVFVSRIRKEKNIKNSLSL
WISTDNLRKGSALNAVQIAENILLQQKLI

Sequences:

>Translated_349_residues
MINVMNNKINIAVIGATGNVGRLLIDILYERQLPIRHLYCISNNLIGHNISFGQQNIVTQSIKNFDFRGINIVFSCVNAQ
VAKSIVPKIVSAGAKVIDKSSYFRLKSDIPLVIPEINIDTITTDSRIISSPNCCVVPLILVLKPLDDVAKIKKLVIATYQ
STSGAGKDAIEELDMQTRNRYLEQSETLTPQIFPKQIAFNIIPQIGMIMENGRCDEEDKIIREIQKIIGRQIAISITCVR
VPTFVSHAFAVNVEFEYNLSVKDAESLLVKLNGIKLISNVKNSMSNISSDIVTPVDVTGKNDVFVSRIRKEKNIKNSLSL
WISTDNLRKGSALNAVQIAENILLQQKLI
>Mature_349_residues
MINVMNNKINIAVIGATGNVGRLLIDILYERQLPIRHLYCISNNLIGHNISFGQQNIVTQSIKNFDFRGINIVFSCVNAQ
VAKSIVPKIVSAGAKVIDKSSYFRLKSDIPLVIPEINIDTITTDSRIISSPNCCVVPLILVLKPLDDVAKIKKLVIATYQ
STSGAGKDAIEELDMQTRNRYLEQSETLTPQIFPKQIAFNIIPQIGMIMENGRCDEEDKIIREIQKIIGRQIAISITCVR
VPTFVSHAFAVNVEFEYNLSVKDAESLLVKLNGIKLISNVKNSMSNISSDIVTPVDVTGKNDVFVSRIRKEKNIKNSLSL
WISTDNLRKGSALNAVQIAENILLQQKLI

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=349, Percent_Identity=30.945558739255, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1789841, Length=358, Percent_Identity=26.536312849162, Blast_Score=95, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320362, Length=294, Percent_Identity=24.8299319727891, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38789; Mature: 38789

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINVMNNKINIAVIGATGNVGRLLIDILYERQLPIRHLYCISNNLIGHNISFGQQNIVTQ
CCEEECCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHH
SIKNFDFRGINIVFSCVNAQVAKSIVPKIVSAGAKVIDKSSYFRLKSDIPLVIPEINIDT
HHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCEEEECCCCEE
ITTDSRIISSPNCCVVPLILVLKPLDDVAKIKKLVIATYQSTSGAGKDAIEELDMQTRNR
EECCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHH
YLEQSETLTPQIFPKQIAFNIIPQIGMIMENGRCDEEDKIIREIQKIIGRQIAISITCVR
HHHHCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCEEEEEEEEEE
VPTFVSHAFAVNVEFEYNLSVKDAESLLVKLNGIKLISNVKNSMSNISSDIVTPVDVTGK
HHHHHCCEEEEEEEEEEECCCCCHHHHEEEECCCHHHHHHHHHHHHHHHHCCCCEECCCC
NDVFVSRIRKEKNIKNSLSLWISTDNLRKGSALNAVQIAENILLQQKLI
CHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MINVMNNKINIAVIGATGNVGRLLIDILYERQLPIRHLYCISNNLIGHNISFGQQNIVTQ
CCEEECCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHH
SIKNFDFRGINIVFSCVNAQVAKSIVPKIVSAGAKVIDKSSYFRLKSDIPLVIPEINIDT
HHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCEEEECCCCEE
ITTDSRIISSPNCCVVPLILVLKPLDDVAKIKKLVIATYQSTSGAGKDAIEELDMQTRNR
EECCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHH
YLEQSETLTPQIFPKQIAFNIIPQIGMIMENGRCDEEDKIIREIQKIIGRQIAISITCVR
HHHHCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCEEEEEEEEEE
VPTFVSHAFAVNVEFEYNLSVKDAESLLVKLNGIKLISNVKNSMSNISSDIVTPVDVTGK
HHHHHCCEEEEEEEEEEECCCCCHHHHEEEECCCHHHHHHHHHHHHHHHHCCCCEECCCC
NDVFVSRIRKEKNIKNSLSLWISTDNLRKGSALNAVQIAENILLQQKLI
CHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA