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The map label for this gene is nuoE [H]

Identifier: 148284883

GI number: 148284883

Start: 1582790

End: 1583368

Strand: Direct

Name: nuoE [H]

Synonym: OTBS_1631

Alternate gene names: 148284883

Gene position: 1582790-1583368 (Clockwise)

Preceding gene: 148284882

Following gene: 148284884

Centisome position: 74.41

GC content: 28.67

Gene sequence:

>579_bases
ATGAATTCAGCTACAAAACCAGAGTTTTCATTTTCCAATGAAACATTAGTAATAGCAAAAAAAATCATTAATAATTACCC
AGCAGGAAAAGAAGCAAGTGCAGTTTTAGCAATATTAGACCTAGCGCAAAATCAAAATAACAATTGGCTTTCTAATAGTT
GTATTGAATATGTTGCAAATTTACTTAAGATGCCATATATCAAGGTGTATGAAATTGCAAGTTTTTATACTATGTTTAAT
CTACAACCAGTAGGTAAATATCATATACAAATTTGCGGTACTACACCATGCTGGTTAAGAGGATCAGATGATATAATGAA
TTTCTGTAAAAAACTATTAAAAATCGAAACTGGCAAAACTTCTCAGGATAAATTATTTACAGTAAGCGAAACTGAATGTC
TTGGAGCTTGTAGAAATGCTCCAGTAGTACAAATTAATCATGATTATTACGAAAATCTTACCAATGATAAAATCAAAGAA
ATTATCAATAACTTGCATGCTAAAGATTTACAAAAAAAATCTGAACTAAAACCTGATAATAAAGCTGACTTATCACTCAA
GAGTAATTATAAATGTTAA

Upstream 100 bases:

>100_bases
CTCATCTACAAGGATTAGATTTTATGGCTCGAGGACATTCACTATCTGATATCATAACCATTATAGCAACACTTGATATA
GTTTTTGGAGAAATAGACAG

Downstream 100 bases:

>100_bases
ATATTGAGGATAAAATTTTTACCAATTTATCTGGGGCTATGGCCGTTGACCTTGCCAGCGCAAAAAAGCGTGGTGACTGG
TATACAACGAAAAATTTAAT

Product: NADH dehydrogenase I chain E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MNSATKPEFSFSNETLVIAKKIINNYPAGKEASAVLAILDLAQNQNNNWLSNSCIEYVANLLKMPYIKVYEIASFYTMFN
LQPVGKYHIQICGTTPCWLRGSDDIMNFCKKLLKIETGKTSQDKLFTVSETECLGACRNAPVVQINHDYYENLTNDKIKE
IINNLHAKDLQKKSELKPDNKADLSLKSNYKC

Sequences:

>Translated_192_residues
MNSATKPEFSFSNETLVIAKKIINNYPAGKEASAVLAILDLAQNQNNNWLSNSCIEYVANLLKMPYIKVYEIASFYTMFN
LQPVGKYHIQICGTTPCWLRGSDDIMNFCKKLLKIETGKTSQDKLFTVSETECLGACRNAPVVQINHDYYENLTNDKIKE
IINNLHAKDLQKKSELKPDNKADLSLKSNYKC
>Mature_192_residues
MNSATKPEFSFSNETLVIAKKIINNYPAGKEASAVLAILDLAQNQNNNWLSNSCIEYVANLLKMPYIKVYEIASFYTMFN
LQPVGKYHIQICGTTPCWLRGSDDIMNFCKKLLKIETGKTSQDKLFTVSETECLGACRNAPVVQINHDYYENLTNDKIKE
IINNLHAKDLQKKSELKPDNKADLSLKSNYKC

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=166, Percent_Identity=53.6144578313253, Blast_Score=186, Evalue=1e-47,
Organism=Escherichia coli, GI1788621, Length=132, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561328, Length=160, Percent_Identity=49.375, Blast_Score=177, Evalue=4e-45,
Organism=Drosophila melanogaster, GI18859877, Length=159, Percent_Identity=52.8301886792453, Blast_Score=186, Evalue=8e-48,
Organism=Drosophila melanogaster, GI21355353, Length=166, Percent_Identity=42.1686746987952, Blast_Score=141, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 21769; Mature: 21769

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSATKPEFSFSNETLVIAKKIINNYPAGKEASAVLAILDLAQNQNNNWLSNSCIEYVAN
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LLKMPYIKVYEIASFYTMFNLQPVGKYHIQICGTTPCWLRGSDDIMNFCKKLLKIETGKT
HHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEECCCHHHHHHHHHHHHHCCCCC
SQDKLFTVSETECLGACRNAPVVQINHDYYENLTNDKIKEIINNLHAKDLQKKSELKPDN
CCCCEEEECHHHHHHHHCCCCEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
KADLSLKSNYKC
CCCEECCCCCCC
>Mature Secondary Structure
MNSATKPEFSFSNETLVIAKKIINNYPAGKEASAVLAILDLAQNQNNNWLSNSCIEYVAN
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LLKMPYIKVYEIASFYTMFNLQPVGKYHIQICGTTPCWLRGSDDIMNFCKKLLKIETGKT
HHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEECCCHHHHHHHHHHHHHCCCCC
SQDKLFTVSETECLGACRNAPVVQINHDYYENLTNDKIKEIINNLHAKDLQKKSELKPDN
CCCCEEEECHHHHHHHHCCCCEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
KADLSLKSNYKC
CCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]