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The map label for this gene is nuoC [H]

Identifier: 148284881

GI number: 148284881

Start: 1580990

End: 1581577

Strand: Direct

Name: nuoC [H]

Synonym: OTBS_1629

Alternate gene names: 148284881

Gene position: 1580990-1581577 (Clockwise)

Preceding gene: 148284880

Following gene: 148284882

Centisome position: 74.33

GC content: 28.74

Gene sequence:

>588_bases
ATGAAATTACATCACCTCAAAGAACTAAAAGAGCTAGTAGAAAGTCAATTTGCTATATCTAGCATTAGCGCTAAGTTTAA
TATTACCAATCACGTTGAAGCAATAATCAATAAGGAACAGTTAATTGAGGTTTTAAAATTACTCAAAAATGACAAAGAAT
TAAAATTTACAATACTAACAGATGTTTTTGCAGCAGATTTTCCAGATCGGAATAAGAGATTTGAGATCGTATATAATTTA
CTTAGTATAATAAAAAATATCAGACTAATAGTTAAGATTAATCTTAATGACAATGAACTAATTCAATCAGCAACCCCGGT
GTTTAGTAATGCAAACTGGTATGAACGTGAAATATATGATCTCTTTGGAATTAAATTTGCTAACCATCCACATTTAAAGC
GTATATTAACAGATTATGGATTTGTTGGGCATCCATTAAGAAAAGATTTTGCTCTTAGTGGATATTCTCAAGTAAAATAT
GATGATAAGCTAGAAAAAGTTGTATATGAACCTGTAAAATTAGATCAAGAATATAGAAATTTTAACTTTTCTTCTCCTTG
GCAAGGGCCAAAATCAACAACTAATTAA

Upstream 100 bases:

>100_bases
TGTCCTCCTACACCAGAAGCTTTACTTTATGGTATTTTACAATTACAAAAAAAAATCAATAGAACTCAACAAGTCAAATT
TAAAAGATAGAGTGTAGTTT

Downstream 100 bases:

>100_bases
CAATTCAACACTAAGTGATATAGTAATGGCATTAAAAAAAAGGTCCAAACACTCTAAAAAATTCAAGTTAAATCTCGGGC
CACAGCATCCTGCTACGCAT

Product: NADH dehydrogenase I chain C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKLHHLKELKELVESQFAISSISAKFNITNHVEAIINKEQLIEVLKLLKNDKELKFTILTDVFAADFPDRNKRFEIVYNL
LSIIKNIRLIVKINLNDNELIQSATPVFSNANWYEREIYDLFGIKFANHPHLKRILTDYGFVGHPLRKDFALSGYSQVKY
DDKLEKVVYEPVKLDQEYRNFNFSSPWQGPKSTTN

Sequences:

>Translated_195_residues
MKLHHLKELKELVESQFAISSISAKFNITNHVEAIINKEQLIEVLKLLKNDKELKFTILTDVFAADFPDRNKRFEIVYNL
LSIIKNIRLIVKINLNDNELIQSATPVFSNANWYEREIYDLFGIKFANHPHLKRILTDYGFVGHPLRKDFALSGYSQVKY
DDKLEKVVYEPVKLDQEYRNFNFSSPWQGPKSTTN
>Mature_195_residues
MKLHHLKELKELVESQFAISSISAKFNITNHVEAIINKEQLIEVLKLLKNDKELKFTILTDVFAADFPDRNKRFEIVYNL
LSIIKNIRLIVKINLNDNELIQSATPVFSNANWYEREIYDLFGIKFANHPHLKRILTDYGFVGHPLRKDFALSGYSQVKY
DDKLEKVVYEPVKLDQEYRNFNFSSPWQGPKSTTN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=160, Percent_Identity=53.125, Blast_Score=182, Evalue=1e-46,
Organism=Escherichia coli, GI145693162, Length=167, Percent_Identity=35.3293413173653, Blast_Score=98, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI32563621, Length=164, Percent_Identity=46.3414634146341, Blast_Score=174, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI71990788, Length=164, Percent_Identity=46.3414634146341, Blast_Score=172, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24656494, Length=184, Percent_Identity=44.5652173913043, Blast_Score=176, Evalue=9e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 22849; Mature: 22849

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHHLKELKELVESQFAISSISAKFNITNHVEAIINKEQLIEVLKLLKNDKELKFTILT
CCCHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHCHHHHHHHHHHHCCCCCEEEEHHH
DVFAADFPDRNKRFEIVYNLLSIIKNIRLIVKINLNDNELIQSATPVFSNANWYEREIYD
HHHHCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHCCCCCCCCCHHHHHHHH
LFGIKFANHPHLKRILTDYGFVGHPLRKDFALSGYSQVKYDDKLEKVVYEPVKLDQEYRN
HHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
FNFSSPWQGPKSTTN
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLHHLKELKELVESQFAISSISAKFNITNHVEAIINKEQLIEVLKLLKNDKELKFTILT
CCCHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHCHHHHHHHHHHHCCCCCEEEEHHH
DVFAADFPDRNKRFEIVYNLLSIIKNIRLIVKINLNDNELIQSATPVFSNANWYEREIYD
HHHHCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHCCCCCCCCCHHHHHHHH
LFGIKFANHPHLKRILTDYGFVGHPLRKDFALSGYSQVKYDDKLEKVVYEPVKLDQEYRN
HHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
FNFSSPWQGPKSTTN
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA