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The map label for this gene is ccmA [H]

Identifier: 148284751

GI number: 148284751

Start: 1353712

End: 1354317

Strand: Direct

Name: ccmA [H]

Synonym: OTBS_1392

Alternate gene names: 148284751

Gene position: 1353712-1354317 (Clockwise)

Preceding gene: 148284750

Following gene: 148284752

Centisome position: 63.64

GC content: 33.83

Gene sequence:

>606_bases
GTGCTCACTTGTCAAAATATATCACTTATATCATCCAATAATACAGTAATATTTGCCAATCTAAGCATTACTTTATTACC
TCGAGCCATAGCAATAATAAGAGGGAAAAATGGTGCTGGCAAAAGTTCATTATTAAAGATAATAGGTAACATACAATCTC
CAACAGCAGGCGAAGTATATATTCATAATATTCAAACTAATAAATTACAAAAGCCTTTTTTAGGGTACATAGGGCATCAA
CTAGGGTTAAAGCTTGACTTAACTGTGGAAGACAATTTAGTTATGTGGGCAAAATTTTATGATTCTGTAACTTTAATTCC
AGCGGCCGTAACATATTTTCGATTAACAGATTTCTTATCAGAAAAAGTATATAAATTGTCTAGCGGTATGAAGAAAAAAG
TAGCACTAGCACGCCTAATGGCATGTTACTCTAAAATATGGCTTCTTGACGAGGTCGAAACTAACTTAGATGAAGAAAAT
CGTAAATTAGTTTACAATTTGATAGCCATACACACTAATTCTGGTGGTATAGTCTTGTGGGCGTCGCATTCTCCATCACC
ATGGCCAAATGCACTGGAAGTTAATTTAGAGCAGTATAAAAAATGA

Upstream 100 bases:

>100_bases
TTTCATATAATTTACTAAATTCACAAGTTTTAAAACCCTAATACTATAAAATTATTACTAGTATTTTGAATTAATTAAAA
ACTAATCAATATAGCTTATA

Downstream 100 bases:

>100_bases
ATAGACTATTACTTTTATTAAAGCATGAAATATATATCTACCATAAAGTTTATACTATACCACAATATGTATTTATTCAT
GCTATAACAGCAATTTTAGC

Product: cytochrome c biogenesis protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MLTCQNISLISSNNTVIFANLSITLLPRAIAIIRGKNGAGKSSLLKIIGNIQSPTAGEVYIHNIQTNKLQKPFLGYIGHQ
LGLKLDLTVEDNLVMWAKFYDSVTLIPAAVTYFRLTDFLSEKVYKLSSGMKKKVALARLMACYSKIWLLDEVETNLDEEN
RKLVYNLIAIHTNSGGIVLWASHSPSPWPNALEVNLEQYKK

Sequences:

>Translated_201_residues
MLTCQNISLISSNNTVIFANLSITLLPRAIAIIRGKNGAGKSSLLKIIGNIQSPTAGEVYIHNIQTNKLQKPFLGYIGHQ
LGLKLDLTVEDNLVMWAKFYDSVTLIPAAVTYFRLTDFLSEKVYKLSSGMKKKVALARLMACYSKIWLLDEVETNLDEEN
RKLVYNLIAIHTNSGGIVLWASHSPSPWPNALEVNLEQYKK
>Mature_201_residues
MLTCQNISLISSNNTVIFANLSITLLPRAIAIIRGKNGAGKSSLLKIIGNIQSPTAGEVYIHNIQTNKLQKPFLGYIGHQ
LGLKLDLTVEDNLVMWAKFYDSVTLIPAAVTYFRLTDFLSEKVYKLSSGMKKKVALARLMACYSKIWLLDEVETNLDEEN
RKLVYNLIAIHTNSGGIVLWASHSPSPWPNALEVNLEQYKK

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI45446740, Length=173, Percent_Identity=27.7456647398844, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI47078218, Length=173, Percent_Identity=27.7456647398844, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI87082064, Length=182, Percent_Identity=34.0659340659341, Blast_Score=88, Evalue=3e-19,
Organism=Escherichia coli, GI87081782, Length=173, Percent_Identity=29.4797687861272, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786698, Length=194, Percent_Identity=29.3814432989691, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789873, Length=196, Percent_Identity=27.5510204081633, Blast_Score=67, Evalue=6e-13,
Organism=Escherichia coli, GI1790525, Length=181, Percent_Identity=27.0718232044199, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1788761, Length=163, Percent_Identity=28.2208588957055, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI87081791, Length=174, Percent_Identity=25.2873563218391, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 22452; Mature: 22452

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTCQNISLISSNNTVIFANLSITLLPRAIAIIRGKNGAGKSSLLKIIGNIQSPTAGEVY
CEEECCEEEEECCCEEEEEEEEEEEECEEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEE
IHNIQTNKLQKPFLGYIGHQLGLKLDLTVEDNLVMWAKFYDSVTLIPAAVTYFRLTDFLS
EEECCCCCCCCHHHHHHHHHHCEEEEEEEECCEEEEEEHHCCCHHHHHHHHHHHHHHHHH
EKVYKLSSGMKKKVALARLMACYSKIWLLDEVETNLDEENRKLVYNLIAIHTNSGGIVLW
HHHHHHHCCHHHHHHHHHHHHHHHHHHEEEHHHCCCCCCCCEEEEEEEEEEECCCCEEEE
ASHSPSPWPNALEVNLEQYKK
ECCCCCCCCCCEEECHHHHCC
>Mature Secondary Structure
MLTCQNISLISSNNTVIFANLSITLLPRAIAIIRGKNGAGKSSLLKIIGNIQSPTAGEVY
CEEECCEEEEECCCEEEEEEEEEEEECEEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEE
IHNIQTNKLQKPFLGYIGHQLGLKLDLTVEDNLVMWAKFYDSVTLIPAAVTYFRLTDFLS
EEECCCCCCCCHHHHHHHHHHCEEEEEEEECCEEEEEEHHCCCHHHHHHHHHHHHHHHHH
EKVYKLSSGMKKKVALARLMACYSKIWLLDEVETNLDEENRKLVYNLIAIHTNSGGIVLW
HHHHHHHCCHHHHHHHHHHHHHHHHHHEEEHHHCCCCCCCCEEEEEEEEEEECCCCEEEE
ASHSPSPWPNALEVNLEQYKK
ECCCCCCCCCCEEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA