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The map label for this gene is tpr1B12

Identifier: 148284641

GI number: 148284641

Start: 1140518

End: 1141180

Strand: Direct

Name: tpr1B12

Synonym: OTBS_1161

Alternate gene names: NA

Gene position: 1140518-1141180 (Clockwise)

Preceding gene: 148284640

Following gene: 148284642

Centisome position: 53.62

GC content: 27.6

Gene sequence:

>663_bases
ATGGAAAATTTTGATATTGCTATTAAGTACAGATCAGATAATCCAGAAGCTTATTATAACAAAGGCATAGCGTTAATGAA
TTTAGGATACATTCAAAATGCAATCGAAAACTATGATATAGCTATTAAATATAGACCAGATTATGCAGAAGCTTATATTA
ATAAAGGTTTAACTTTAGCATTTTTAGGGCAATTGCAGAATGCAATAGAACATTTTGATTTAGCTATTAAATACGATCCT
AGTTGTGTGAAATCATACTGTAATAAAGGGTATATATTAAGCTTATTGAATAGATATTCTGAAGCAATAGAAAGCTGTAA
CATAGCTATTAAATATGATCCAAATTGTGCGGATATTTATTATAATAAAGGAATGATTCTTGAGAAATTAGGTAAACACC
AAAAAGCGATAGAAAATTTTGACATTGCTATCGCTATTAAGTACAAACCTAATTTTGCTGAAAACTATCTTGAAAAAGGA
ATTTCATTAGTAAGTTTAGGACAGTACTCAAAAGCTAAGGAGAATTTTAACTTAGCTATTAAATATAATCCTAATATCAT
TGCAGAATACGAAGCAATGTTTAAAAAGTTAACAGAATTAGAGAATTTTACTGGAGTAAAAGAGTATGAGCAAAAACTAC
AGATTTTGAAAAAATACTCTTGA

Upstream 100 bases:

>100_bases
TGGTGGTAGAGCATTTTTTGCACAAGTTAAAGTTGAAGGAGTGGAAAGACATAACAATAAAGGAGCTTCTTTAGCTAGAT
TAGGACAGTATGAAGATGCA

Downstream 100 bases:

>100_bases
TGAATTTTCAGAATCAAGGCAATTTCACAAGGGGATCGCAGTTATTTGCTCATAAGTTAAGAATGTTTGGGCAAGGTAGT
GCCAATGTTTTTACAATTGG

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MENFDIAIKYRSDNPEAYYNKGIALMNLGYIQNAIENYDIAIKYRPDYAEAYINKGLTLAFLGQLQNAIEHFDLAIKYDP
SCVKSYCNKGYILSLLNRYSEAIESCNIAIKYDPNCADIYYNKGMILEKLGKHQKAIENFDIAIAIKYKPNFAENYLEKG
ISLVSLGQYSKAKENFNLAIKYNPNIIAEYEAMFKKLTELENFTGVKEYEQKLQILKKYS

Sequences:

>Translated_220_residues
MENFDIAIKYRSDNPEAYYNKGIALMNLGYIQNAIENYDIAIKYRPDYAEAYINKGLTLAFLGQLQNAIEHFDLAIKYDP
SCVKSYCNKGYILSLLNRYSEAIESCNIAIKYDPNCADIYYNKGMILEKLGKHQKAIENFDIAIAIKYKPNFAENYLEKG
ISLVSLGQYSKAKENFNLAIKYNPNIIAEYEAMFKKLTELENFTGVKEYEQKLQILKKYS
>Mature_220_residues
MENFDIAIKYRSDNPEAYYNKGIALMNLGYIQNAIENYDIAIKYRPDYAEAYINKGLTLAFLGQLQNAIEHFDLAIKYDP
SCVKSYCNKGYILSLLNRYSEAIESCNIAIKYDPNCADIYYNKGMILEKLGKHQKAIENFDIAIAIKYKPNFAENYLEKG
ISLVSLGQYSKAKENFNLAIKYNPNIIAEYEAMFKKLTELENFTGVKEYEQKLQILKKYS

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=183, Percent_Identity=31.6939890710383, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI32307150, Length=183, Percent_Identity=31.6939890710383, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI118766330, Length=197, Percent_Identity=28.9340101522843, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI118766328, Length=197, Percent_Identity=28.9340101522843, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI310123097, Length=200, Percent_Identity=28.5, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI310110582, Length=200, Percent_Identity=28.5, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI310131789, Length=200, Percent_Identity=28.5, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI54607135, Length=187, Percent_Identity=28.3422459893048, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=158, Percent_Identity=32.9113924050633, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115532690, Length=158, Percent_Identity=32.9113924050633, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17647755, Length=183, Percent_Identity=30.0546448087432, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24585827, Length=183, Percent_Identity=30.0546448087432, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24585829, Length=183, Percent_Identity=30.0546448087432, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647123, Length=215, Percent_Identity=27.4418604651163, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 25404; Mature: 25404

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENFDIAIKYRSDNPEAYYNKGIALMNLGYIQNAIENYDIAIKYRPDYAEAYINKGLTLA
CCCCEEEEEEECCCCHHHHHCCEEEEEHHHHHHHHCCCEEEEEECCCHHHHHHCCCCHHH
FLGQLQNAIEHFDLAIKYDPSCVKSYCNKGYILSLLNRYSEAIESCNIAIKYDPNCADIY
HHHHHHHHHHHHEEEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEEE
YNKGMILEKLGKHQKAIENFDIAIAIKYKPNFAENYLEKGISLVSLGQYSKAKENFNLAI
ECCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHCCCCEEECCCCCCCCCCCEEEE
KYNPNIIAEYEAMFKKLTELENFTGVKEYEQKLQILKKYS
EECCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MENFDIAIKYRSDNPEAYYNKGIALMNLGYIQNAIENYDIAIKYRPDYAEAYINKGLTLA
CCCCEEEEEEECCCCHHHHHCCEEEEEHHHHHHHHCCCEEEEEECCCHHHHHHCCCCHHH
FLGQLQNAIEHFDLAIKYDPSCVKSYCNKGYILSLLNRYSEAIESCNIAIKYDPNCADIY
HHHHHHHHHHHHEEEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEEE
YNKGMILEKLGKHQKAIENFDIAIAIKYKPNFAENYLEKGISLVSLGQYSKAKENFNLAI
ECCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHCCCCEEECCCCCCCCCCCEEEE
KYNPNIIAEYEAMFKKLTELENFTGVKEYEQKLQILKKYS
EECCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]