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The map label for this gene is tpr1B9 [C]

Identifier: 148284415

GI number: 148284415

Start: 694297

End: 695271

Strand: Direct

Name: tpr1B9 [C]

Synonym: OTBS_0721

Alternate gene names: 148284415

Gene position: 694297-695271 (Clockwise)

Preceding gene: 148284414

Following gene: 148284416

Centisome position: 32.64

GC content: 29.95

Gene sequence:

>975_bases
ATGTGGCAACTAGCTACTCTACTTGATTACCAACTGATTAATGCTAATGAGCCTGCTAATAGCTTACATAGAAAGCTATA
TCAAGAAAAATCAGAGCAGAAAGAAGCTATAGAAAATTATAATTTAGCTATTAAGAACAAACCTGATTTTGCAGAAGCTT
ATAATAACAAAGGAGCATCTTATGGGAAGTTAGAAAAAGATAAAGAGGCTATAACACTTTGTAATCTTGCAATTAAGTAT
AAACCTCATTTTGCAGAAGCTTATAATAATAAAGGAGTTTCTTTGGCTATATTAGGAAAGTATGAAGATGCGCTGGAAAA
TTTTGATATTGCTATTAAGTACAGATCAGATAATCCAGAAGCTTATTATAACAAAGGTATAGCGTTAATGTATTTAGGCT
ACATTCAAGAAGCTATTGAAAACTATGATACAGCTATTAGATACAGACCAAATTATTCAGAAGCATATCATAATAAAGGA
TTAACTTTAGCATTTTTAGGACAATTTCAGAAAGCAATAGAACATTTTGATTTAGCTATTAAATACGATCCTAATGATGC
AACAGCATACTGTAATAAAGGTTATGTGCTAAGTATGTTAAAAAGGTATTCTGAAGCAATAGAAAGCTGCAATCTAGCAA
TTAAATACAATCCAAATTGTGCAGAGGCTTACTACCGTAGAGGAATGATTTTTGAGAAATTAGGTAAACACCAAAAAGCG
ATAGAAAATTTTGACATTGCTATCGCTATTAAGTACAAACCTAATTTTGCTGAAAACTATCTTGAAAAAGGAATTTCATT
AGTAAGTTTAGGACAGTACTCAAAAGCTAAGGAGAATTTTAACTTAGCTATTAAATATAATCCTAATATCATTGCAGAAT
ACGAAGCAATGTTTAAAAAGTTAACAGAATTAGAGAATTTTACTGGAGTAAAAGAGTATGAGCAAAAACTACAGATTTTG
AAAAAATACTCTTGA

Upstream 100 bases:

>100_bases
AGCTTAGCGTATAGCGCTGGATAATCCAACGCTCGAAAATGTGATTACAGCTCAAAGATTGCAGAAGCAAATCATGGAGA
AGGCTCATAAGTTTGCTACT

Downstream 100 bases:

>100_bases
TGAATTTTCAGAATCAAGGCAATTTCACAAGGGGATCGCAGTTATTTGCTCATAAGTTAAGAATGTTTGGGCAAGGTAGT
GCCAATGTTTTTACAATTGG

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MWQLATLLDYQLINANEPANSLHRKLYQEKSEQKEAIENYNLAIKNKPDFAEAYNNKGASYGKLEKDKEAITLCNLAIKY
KPHFAEAYNNKGVSLAILGKYEDALENFDIAIKYRSDNPEAYYNKGIALMYLGYIQEAIENYDTAIRYRPNYSEAYHNKG
LTLAFLGQFQKAIEHFDLAIKYDPNDATAYCNKGYVLSMLKRYSEAIESCNLAIKYNPNCAEAYYRRGMIFEKLGKHQKA
IENFDIAIAIKYKPNFAENYLEKGISLVSLGQYSKAKENFNLAIKYNPNIIAEYEAMFKKLTELENFTGVKEYEQKLQIL
KKYS

Sequences:

>Translated_324_residues
MWQLATLLDYQLINANEPANSLHRKLYQEKSEQKEAIENYNLAIKNKPDFAEAYNNKGASYGKLEKDKEAITLCNLAIKY
KPHFAEAYNNKGVSLAILGKYEDALENFDIAIKYRSDNPEAYYNKGIALMYLGYIQEAIENYDTAIRYRPNYSEAYHNKG
LTLAFLGQFQKAIEHFDLAIKYDPNDATAYCNKGYVLSMLKRYSEAIESCNLAIKYNPNCAEAYYRRGMIFEKLGKHQKA
IENFDIAIAIKYKPNFAENYLEKGISLVSLGQYSKAKENFNLAIKYNPNIIAEYEAMFKKLTELENFTGVKEYEQKLQIL
KKYS
>Mature_324_residues
MWQLATLLDYQLINANEPANSLHRKLYQEKSEQKEAIENYNLAIKNKPDFAEAYNNKGASYGKLEKDKEAITLCNLAIKY
KPHFAEAYNNKGVSLAILGKYEDALENFDIAIKYRSDNPEAYYNKGIALMYLGYIQEAIENYDTAIRYRPNYSEAYHNKG
LTLAFLGQFQKAIEHFDLAIKYDPNDATAYCNKGYVLSMLKRYSEAIESCNLAIKYNPNCAEAYYRRGMIFEKLGKHQKA
IENFDIAIAIKYKPNFAENYLEKGISLVSLGQYSKAKENFNLAIKYNPNIIAEYEAMFKKLTELENFTGVKEYEQKLQIL
KKYS

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=259, Percent_Identity=30.8880308880309, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI32307148, Length=259, Percent_Identity=30.8880308880309, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI310123097, Length=261, Percent_Identity=27.9693486590038, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI310110582, Length=261, Percent_Identity=27.9693486590038, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI310131789, Length=261, Percent_Identity=27.9693486590038, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI118766330, Length=222, Percent_Identity=27.9279279279279, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI118766328, Length=222, Percent_Identity=27.9279279279279, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI83415184, Length=328, Percent_Identity=24.6951219512195, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI301336134, Length=328, Percent_Identity=24.6951219512195, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI54607135, Length=182, Percent_Identity=30.2197802197802, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI170784867, Length=249, Percent_Identity=26.9076305220884, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI221219056, Length=198, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI262206280, Length=197, Percent_Identity=27.4111675126904, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115532692, Length=259, Percent_Identity=29.7297297297297, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI115532690, Length=259, Percent_Identity=29.7297297297297, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI25147174, Length=239, Percent_Identity=25.1046025104602, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319387, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17647755, Length=259, Percent_Identity=30.1158301158301, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24585827, Length=259, Percent_Identity=30.1158301158301, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24585829, Length=259, Percent_Identity=30.1158301158301, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24647123, Length=230, Percent_Identity=28.2608695652174, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19920486, Length=236, Percent_Identity=26.6949152542373, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI161076610, Length=236, Percent_Identity=26.6949152542373, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 37452; Mature: 37452

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWQLATLLDYQLINANEPANSLHRKLYQEKSEQKEAIENYNLAIKNKPDFAEAYNNKGAS
CCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHCCCCCC
YGKLEKDKEAITLCNLAIKYKPHFAEAYNNKGVSLAILGKYEDALENFDIAIKYRSDNPE
CCCCCCCHHHEEHHHEEEEECCCHHHHHCCCCEEEEEECCHHHHHCCCEEEEEEECCCCH
AYYNKGIALMYLGYIQEAIENYDTAIRYRPNYSEAYHNKGLTLAFLGQFQKAIEHFDLAI
HHHHCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHCCEEE
KYDPNDATAYCNKGYVLSMLKRYSEAIESCNLAIKYNPNCAEAYYRRGMIFEKLGKHQKA
EECCCCCCEEECCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCHHHHHHCHHHHH
IENFDIAIAIKYKPNFAENYLEKGISLVSLGQYSKAKENFNLAIKYNPNIIAEYEAMFKK
HHCCCEEEEEEECCCHHHHHHHCCCCEEECCCCCCCCCCCEEEEEECCCEEEHHHHHHHH
LTELENFTGVKEYEQKLQILKKYS
HHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MWQLATLLDYQLINANEPANSLHRKLYQEKSEQKEAIENYNLAIKNKPDFAEAYNNKGAS
CCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHCCCCCC
YGKLEKDKEAITLCNLAIKYKPHFAEAYNNKGVSLAILGKYEDALENFDIAIKYRSDNPE
CCCCCCCHHHEEHHHEEEEECCCHHHHHCCCCEEEEEECCHHHHHCCCEEEEEEECCCCH
AYYNKGIALMYLGYIQEAIENYDTAIRYRPNYSEAYHNKGLTLAFLGQFQKAIEHFDLAI
HHHHCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHCCEEE
KYDPNDATAYCNKGYVLSMLKRYSEAIESCNLAIKYNPNCAEAYYRRGMIFEKLGKHQKA
EECCCCCCEEECCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCHHHHHHCHHHHH
IENFDIAIAIKYKPNFAENYLEKGISLVSLGQYSKAKENFNLAIKYNPNIIAEYEAMFKK
HHCCCEEEEEEECCCHHHHHHHCCCCEEECCCCCCCCCCCEEEEEECCCEEEHHHHHHHH
LTELENFTGVKEYEQKLQILKKYS
HHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]