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The map label for this gene is nrdR

Identifier: 148261113

GI number: 148261113

Start: 2349588

End: 2350043

Strand: Reverse

Name: nrdR

Synonym: Acry_2122

Alternate gene names: 148261113

Gene position: 2350043-2349588 (Counterclockwise)

Preceding gene: 148261114

Following gene: 148261112

Centisome position: 69.34

GC content: 64.91

Gene sequence:

>456_bases
GTGCGCTGCCCGTTCTGCGGCGAGGCCGATACCCAGGTCAAGGACAGCCGGCCGACGGAGGATGGCGCCGCCATCCGTCG
CCGGCGCTTCTGCCCGCAGTGCAGCCAGCGTTTCACCACGATCGAGCGCGTGCAGCTGCGCGAGCTGGTCGTGGTGAAGG
CCGATCAGCGGCGGGTCGCGTTCGATCGTGACAAGCTGGCCCGCTCGATCCGCACCGCGCTGCGCAAGCGACCCGTCGAT
GACGAGCGGATCGAGCGGATCGTCAACGGCATCGTCCGCAAGCTGGAAGCCTCGGGCGAGGCGGAAATTCCGTCCAGCGA
GATTGGCGAGCTGGTGATGGATACGTTGAAAGAGGTCGATGCGGTGGCCTATGTGCGCTTCGCCTCGGTCTATCGCGATT
TCCGGGAAGCCAAGGATTTCAAGGCCTTCCTGGGTACGATGGACCCATCGAAATAG

Upstream 100 bases:

>100_bases
CTCCGCATCGAACGACGGTGACAACGCCGCCGTCGAGGCGGCGGTGGGCGCCAAGGTGCTGGAGCTCTGCGCCCGGTTCC
CGATCTACCGGTAAAAAAGC

Downstream 100 bases:

>100_bases
GCATGGACGATCTCGCGCATATGCGGACGGCCCTCGCGCTCGCACGGCGCGGCCTGGGCGAGACCGCGCCGAATCCGACC
GTCGGCTGCGTGATCGTGCG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MRCPFCGEADTQVKDSRPTEDGAAIRRRRFCPQCSQRFTTIERVQLRELVVVKADQRRVAFDRDKLARSIRTALRKRPVD
DERIERIVNGIVRKLEASGEAEIPSSEIGELVMDTLKEVDAVAYVRFASVYRDFREAKDFKAFLGTMDPSK

Sequences:

>Translated_151_residues
MRCPFCGEADTQVKDSRPTEDGAAIRRRRFCPQCSQRFTTIERVQLRELVVVKADQRRVAFDRDKLARSIRTALRKRPVD
DERIERIVNGIVRKLEASGEAEIPSSEIGELVMDTLKEVDAVAYVRFASVYRDFREAKDFKAFLGTMDPSK
>Mature_151_residues
MRCPFCGEADTQVKDSRPTEDGAAIRRRRFCPQCSQRFTTIERVQLRELVVVKADQRRVAFDRDKLARSIRTALRKRPVD
DERIERIVNGIVRKLEASGEAEIPSSEIGELVMDTLKEVDAVAYVRFASVYRDFREAKDFKAFLGTMDPSK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=140, Percent_Identity=48.5714285714286, Blast_Score=134, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_ACICJ (A5G0D9)

Other databases:

- EMBL:   CP000697
- RefSeq:   YP_001235240.1
- STRING:   A5G0D9
- GeneID:   5159624
- GenomeReviews:   CP000697_GR
- KEGG:   acr:Acry_2122
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   ACRY349163:ACRY_2122-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17370; Mature: 17370

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCGEADTQVKDSRPTEDGAAIRRRRFCPQCSQRFTTIERVQLRELVVVKADQRRVA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FDRDKLARSIRTALRKRPVDDERIERIVNGIVRKLEASGEAEIPSSEIGELVMDTLKEVD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
AVAYVRFASVYRDFREAKDFKAFLGTMDPSK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRCPFCGEADTQVKDSRPTEDGAAIRRRRFCPQCSQRFTTIERVQLRELVVVKADQRRVA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FDRDKLARSIRTALRKRPVDDERIERIVNGIVRKLEASGEAEIPSSEIGELVMDTLKEVD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
AVAYVRFASVYRDFREAKDFKAFLGTMDPSK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA