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The map label for this gene is prpC [H]

Identifier: 148261077

GI number: 148261077

Start: 2296859

End: 2297578

Strand: Reverse

Name: prpC [H]

Synonym: Acry_2086

Alternate gene names: 148261077

Gene position: 2297578-2296859 (Counterclockwise)

Preceding gene: 148261078

Following gene: 148261070

Centisome position: 67.79

GC content: 71.53

Gene sequence:

>720_bases
ATGATCCCGCGCGCCGTGACCTGGGCGGAAACCCATGTCGGCGCGGTGCGCAGGCACAACGAGGATGCCTATCTCTGCCG
CCCCGATCTCGGCCTCTGGGCGGTGGCGGACGGTGCCGGGGGGCATCAGGCGGGCGAGGTGGCCTCGGGGATGATCGTCG
CCGGGCTGGACCGCCTCGAGCCGGGGCTGACCGCGGCCGAATTGCTGCCGCAGGTGCGGGGCGTGGTGAACGAGACCCAT
CACGCCCTGCTGCACGAGGCGTCCCAGCGCGGCCCGCGCGCGGTCATCGCCTCCACGATCGCGATCCTGATCCTGCGCGA
TGACCATTTCGCCTGCCTCTGGGCGGGGGATTCGCGCGTCTATCTGCTGCGCGGCGGCGAGTTGACCCAGCTGACCCGCG
ACCACTCGCTGGTGCAGGCGCTGGTGGACGAGGGCCGGCTCACGCCCGAGGCCGCCGAGCACCATCCCCAGGCGAACGTG
ATTACCCGCGCCGTCGGCGCCGACGACGCGGATCTCGAACTCGACAAGGTGATCGGCCGGATCGAGCCGGGGGACCGGTT
CCTGCTCTGCTCGGACGGGCTGAGCAAGACATTGCCCGAGGCGGAAATCGCCGCCCTGCTCGGTTCGCCGGACGGCGTGC
CGCCGCCGGAACTGCTGATCGCGGCCACCCTCGCCCGCAAGGGCAACGACAACGTGACGGCCGTGGTCGTCGCGGTCTGA

Upstream 100 bases:

>100_bases
GGGGGCCGCATCGCGGTCCTGGCCGCATCGAGGTCGCCGGCTTGCCCGACCCCGCCGGTTTCGCGGCGTTCCTGCGCGAT
GAGGCCGGGGAGACGGTGCG

Downstream 100 bases:

>100_bases
CCGCCCCTCACCGTGAAAGCCGCGCCGCGATCCGGTCGGCGAGCCGGCCGAGCGCGACGCTCATGGCGTGCGCTTCCGCC
GCCGCGCCTCCGCCGCAACG

Product: protein phosphatase 2C domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MIPRAVTWAETHVGAVRRHNEDAYLCRPDLGLWAVADGAGGHQAGEVASGMIVAGLDRLEPGLTAAELLPQVRGVVNETH
HALLHEASQRGPRAVIASTIAILILRDDHFACLWAGDSRVYLLRGGELTQLTRDHSLVQALVDEGRLTPEAAEHHPQANV
ITRAVGADDADLELDKVIGRIEPGDRFLLCSDGLSKTLPEAEIAALLGSPDGVPPPELLIAATLARKGNDNVTAVVVAV

Sequences:

>Translated_239_residues
MIPRAVTWAETHVGAVRRHNEDAYLCRPDLGLWAVADGAGGHQAGEVASGMIVAGLDRLEPGLTAAELLPQVRGVVNETH
HALLHEASQRGPRAVIASTIAILILRDDHFACLWAGDSRVYLLRGGELTQLTRDHSLVQALVDEGRLTPEAAEHHPQANV
ITRAVGADDADLELDKVIGRIEPGDRFLLCSDGLSKTLPEAEIAALLGSPDGVPPPELLIAATLARKGNDNVTAVVVAV
>Mature_239_residues
MIPRAVTWAETHVGAVRRHNEDAYLCRPDLGLWAVADGAGGHQAGEVASGMIVAGLDRLEPGLTAAELLPQVRGVVNETH
HALLHEASQRGPRAVIASTIAILILRDDHFACLWAGDSRVYLLRGGELTQLTRDHSLVQALVDEGRLTPEAAEHHPQANV
ITRAVGADDADLELDKVIGRIEPGDRFLLCSDGLSKTLPEAEIAALLGSPDGVPPPELLIAATLARKGNDNVTAVVVAV

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 25320; Mature: 25320

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPRAVTWAETHVGAVRRHNEDAYLCRPDLGLWAVADGAGGHQAGEVASGMIVAGLDRLE
CCCCCEEHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCCCCCCHHHHCCHHEECHHHCC
PGLTAAELLPQVRGVVNETHHALLHEASQRGPRAVIASTIAILILRDDHFACLWAGDSRV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEEEECCCEEEEEECCCEE
YLLRGGELTQLTRDHSLVQALVDEGRLTPEAAEHHPQANVITRAVGADDADLELDKVIGR
EEEECCCEEHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHCCCCCCCCCCHHHHHCC
IEPGDRFLLCSDGLSKTLPEAEIAALLGSPDGVPPPELLIAATLARKGNDNVTAVVVAV
CCCCCEEEEECCCCCHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEC
>Mature Secondary Structure
MIPRAVTWAETHVGAVRRHNEDAYLCRPDLGLWAVADGAGGHQAGEVASGMIVAGLDRLE
CCCCCEEHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCCCCCCHHHHCCHHEECHHHCC
PGLTAAELLPQVRGVVNETHHALLHEASQRGPRAVIASTIAILILRDDHFACLWAGDSRV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEEEECCCEEEEEECCCEE
YLLRGGELTQLTRDHSLVQALVDEGRLTPEAAEHHPQANVITRAVGADDADLELDKVIGR
EEEECCCEEHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHCCCCCCCCCCHHHHHCC
IEPGDRFLLCSDGLSKTLPEAEIAALLGSPDGVPPPELLIAATLARKGNDNVTAVVVAV
CCCCCEEEEECCCCCHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]