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The map label for this gene is ampR [H]

Identifier: 148261066

GI number: 148261066

Start: 2282987

End: 2283949

Strand: Reverse

Name: ampR [H]

Synonym: Acry_2074

Alternate gene names: 148261066

Gene position: 2283949-2282987 (Counterclockwise)

Preceding gene: 148261067

Following gene: 148261059

Centisome position: 67.39

GC content: 71.34

Gene sequence:

>963_bases
ATGACAGACAAATCGCCGATCAACCGACGCTGGCTGCCGCTCAACGCCCTGCGCGCCTTCGAGGCGGTCGGCCGGCATTC
CAGCTTCACCGCCGGCGGCCATGCGCTCAACGTCTCGCAATCGGCGCTCAGCCGGCACGTGCAGACGCTGGAGGCGCTGC
TCGGCTGCCCGCTGCTGATCCGCCATCCGCACGGGCTGGAGACCACCGAGGCCGGGCGGCGGCTGCTGCCGGCGATCAGC
CGCGGCTTCGACGGCATCGAGCGCGAGATGAACGAGATCATCCGCAACCGCGGCCGCGACCGCCACCTGCGCACGCTGCG
CGTGCACATGCCGCCGAGCTTCCTCCAGCAGGTGGGGCTGCCGGCGCTGAAATCGTTCCGCCGGGAATATCCCGACATCA
TCATCGACGTCGCCTCCTCCTACGTGACCGGCTGGCCGCGGGAGGAGCCGGACATCGCCGTGGTGTACGACCGGCCGCAG
GCGGGGCAGTCGGTCACCGACCTGCTGTGGATGATCCATGTCGCCCCGGCCTGCGCGCCGGAGATCGCCCGCGAGCACGA
GGGCAAGACGCTGGAGCGGTTCCTGCGCGACACCGAGCTGCTGCACGTGAAGCTCCAGGGCCAGGCGCGGGGGCTGATGT
GGGCGAGCTATATCCGCCAGCGCGGGCTGGAGGTGGACACCGATCGCGGCCTCGCCTTCGAGACCGCGAGCGCGGCCACC
GGCTATGCGATGACGGGCGGCGGGGTGGCGCTGATCGACCTCGTGCTGTTCGCGCAGGAGATCGCCGCGGGGCGGCTCGT
GGTGCCGTATCCGGAGCCGGCGGAGGAGGGCTACGGCTATTTCCTGACGATGCGGCCGGAGGACATGGCGGACCCGATCC
TCGCGCTGTTCCGCACCTGGATGATCGAGCATTGCGCGCGGCCGGAGCCGCCGCCGCTGCTGCGGGCGGCGGCCGCGCCG
TAG

Upstream 100 bases:

>100_bases
GACGCGCTGGGGCGGCGCGGGGCGTAGCGGCCGGCCGGGCGTGGCACCCCTTGCGCGCGATTCGTTAGAGAGGCAACCTG
ACGATCCGCATGGTCGTGGC

Downstream 100 bases:

>100_bases
GGTGACTCAGTCCGGGATGTCGAGCCCGGCGGCCCAGCGGGTGAGGGACGCCGCGTCGCGCTCGCCGGCGACGGCGCCGG
CCACCGCGTCGCCCATCAGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTDKSPINRRWLPLNALRAFEAVGRHSSFTAGGHALNVSQSALSRHVQTLEALLGCPLLIRHPHGLETTEAGRRLLPAIS
RGFDGIEREMNEIIRNRGRDRHLRTLRVHMPPSFLQQVGLPALKSFRREYPDIIIDVASSYVTGWPREEPDIAVVYDRPQ
AGQSVTDLLWMIHVAPACAPEIAREHEGKTLERFLRDTELLHVKLQGQARGLMWASYIRQRGLEVDTDRGLAFETASAAT
GYAMTGGGVALIDLVLFAQEIAAGRLVVPYPEPAEEGYGYFLTMRPEDMADPILALFRTWMIEHCARPEPPPLLRAAAAP

Sequences:

>Translated_320_residues
MTDKSPINRRWLPLNALRAFEAVGRHSSFTAGGHALNVSQSALSRHVQTLEALLGCPLLIRHPHGLETTEAGRRLLPAIS
RGFDGIEREMNEIIRNRGRDRHLRTLRVHMPPSFLQQVGLPALKSFRREYPDIIIDVASSYVTGWPREEPDIAVVYDRPQ
AGQSVTDLLWMIHVAPACAPEIAREHEGKTLERFLRDTELLHVKLQGQARGLMWASYIRQRGLEVDTDRGLAFETASAAT
GYAMTGGGVALIDLVLFAQEIAAGRLVVPYPEPAEEGYGYFLTMRPEDMADPILALFRTWMIEHCARPEPPPLLRAAAAP
>Mature_319_residues
TDKSPINRRWLPLNALRAFEAVGRHSSFTAGGHALNVSQSALSRHVQTLEALLGCPLLIRHPHGLETTEAGRRLLPAISR
GFDGIEREMNEIIRNRGRDRHLRTLRVHMPPSFLQQVGLPALKSFRREYPDIIIDVASSYVTGWPREEPDIAVVYDRPQA
GQSVTDLLWMIHVAPACAPEIAREHEGKTLERFLRDTELLHVKLQGQARGLMWASYIRQRGLEVDTDRGLAFETASAATG
YAMTGGGVALIDLVLFAQEIAAGRLVVPYPEPAEEGYGYFLTMRPEDMADPILALFRTWMIEHCARPEPPPLLRAAAAP

Specific function: This protein is a positive regulator of gene expression of cephalosporinase (AmpC) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786448, Length=294, Percent_Identity=29.9319727891156, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789173, Length=303, Percent_Identity=30.3630363036304, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788706, Length=295, Percent_Identity=27.4576271186441, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35690; Mature: 35558

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKSPINRRWLPLNALRAFEAVGRHSSFTAGGHALNVSQSALSRHVQTLEALLGCPLLI
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCEEE
RHPHGLETTEAGRRLLPAISRGFDGIEREMNEIIRNRGRDRHLRTLRVHMPPSFLQQVGL
ECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHCCC
PALKSFRREYPDIIIDVASSYVTGWPREEPDIAVVYDRPQAGQSVTDLLWMIHVAPACAP
HHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
EIAREHEGKTLERFLRDTELLHVKLQGQARGLMWASYIRQRGLEVDTDRGLAFETASAAT
HHHHHCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCC
GYAMTGGGVALIDLVLFAQEIAAGRLVVPYPEPAEEGYGYFLTMRPEDMADPILALFRTW
CCEECCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
MIEHCARPEPPPLLRAAAAP
HHHHHCCCCCCCHHHCCCCC
>Mature Secondary Structure 
TDKSPINRRWLPLNALRAFEAVGRHSSFTAGGHALNVSQSALSRHVQTLEALLGCPLLI
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCEEE
RHPHGLETTEAGRRLLPAISRGFDGIEREMNEIIRNRGRDRHLRTLRVHMPPSFLQQVGL
ECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHCCC
PALKSFRREYPDIIIDVASSYVTGWPREEPDIAVVYDRPQAGQSVTDLLWMIHVAPACAP
HHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
EIAREHEGKTLERFLRDTELLHVKLQGQARGLMWASYIRQRGLEVDTDRGLAFETASAAT
HHHHHCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCC
GYAMTGGGVALIDLVLFAQEIAAGRLVVPYPEPAEEGYGYFLTMRPEDMADPILALFRTW
CCEECCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
MIEHCARPEPPPLLRAAAAP
HHHHHCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3030737 [H]