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The map label for this gene is aceE [H]

Identifier: 148261057

GI number: 148261057

Start: 2269610

End: 2272015

Strand: Reverse

Name: aceE [H]

Synonym: Acry_2065

Alternate gene names: 148261057

Gene position: 2272015-2269610 (Counterclockwise)

Preceding gene: 148261059

Following gene: 148261056

Centisome position: 67.04

GC content: 71.7

Gene sequence:

>2406_bases
ATGACGCCGCATCTGAAAACCGCCGAACAGCGCCTGCTCTGGCTGTCGCACTGGATGATCCACAACGCCAACCACCTCCG
GCCGAAAGTGGACGGGATCAAGACCGGCGGGCATCAGGCCTCCTCCGCCTCGATGGTGGGCATCATGGCGGCGCTCTATT
TCACCGCGCTGCGCCCGGAGGACCGCGTCGCGGTGAAGCCGCACGCCGCCCCGGTGTTTCACGCGATGCAATACCTGATG
GGCAACACCACGCGCGAGCGGCTGGAGACTTTCCGCGGCTTCGGCGGCACCCAGAGCTATCCGAGCCGCACCAAGGACGA
TGACGACGTGGATTTCTCCACCGGATCGGTGGGCCTCGGCGTCGCCATCACCTCCTTCGCCGCGCTGGTGCAGGACTATA
TCGCGGCGAAGCAATGGGGGCGGGATGTGCGGCGCGGCCGCATGGTCGCGCTGATGGGCGATGCCGAGATCGACGAGGGC
AACATCCACGAATGCCTCCAGGAAGGCTGGAAGAACGGGCTGCGCGATGTCTGGTGGGTGATCGACTACAACCGCCAGTC
GCTCGACGGGGTGGCCCGCGAGGGGCTGTGGCAGCGCATCGAGAAGATCTTCGAGGCGTTCGGCTGGGATGTGGTGCGGA
TCAAGTACGGCGCGTTGCAGCGCGCGGCCTTCGCCGAGCCGGGCGGGGAGGCGCTGCGAAACTGGATCGATTCCTGCCCC
AACCAGCGCTACGCAGCACTCACCTTCCAGGGCGGCGCGGCCTGGCGCAAGCGCCTGCTCGACGAGCTGGGCGACCAGGG
CGCGGTCTCGGCGCTGATCGCCCGGCGCAGCGATGCCGAGCTGGCCGCGCTGATGGAGAATCTCGGCGGCAACTGCGTGC
AGACCATGGCCGACACCTTCGCCGCGATCGACCACGACCGCCCGACCTGCTTCCTCGCCTACACGATCAAGGGCTGGGGC
ACGCCGATCGCCGGGCACAAGGACAATCACGGCGGGGTGATGACGGTCGAGCAGATGCAGGCCTGGCAGCGCCACATGGG
CGTGGGGCAGGGCGAGGAGTGGGAGCGTTTCGCCGCGGTGGCGGACGTGGAGGGCTTCCGCGCCTGGCTCGACGCGGTGC
CCTTCTTCGCCGCCGGCCGCCGCCGGCACGACGATGCGCATCTGCCGGTCCCCGCCCTCGCTTCACCCGGCGAGCGGGAG
ATCTCCACCCAGGCCGCCTTCGGCCGCATCCTCGACGATCTCGCCCGCGGCGACAGCGCGCTCGCCGCGCGCATCCTCAC
CACCTCGCCCGACGTCACCGGCACCACCTCGCTCGGCCCCTGGGTCAACCGCCGCCGCCTGTTCGCCCGCGAGGCGATGG
CCGACCTCTTCCGCGCCGAGAAGATCCCCTCGACCGCGCGCTGGGATTTCGCGCCCGAGGGCCAGCATCTCGAACTCGGC
ATCGCCGAGACCAACCTGATGCTGCTGCTCGCCGCCGCCGGCCTCGCCCGTTCGCTGTTCGGCCGCCGCCTCATCCCCAT
CGGCACCGTCTACGATCCGTTCATCGCCCGCGGGCTCGATGCGCTGAACTACGCCTGTTACCAGGATGCCCGCTTCCTGC
TGGTCGGCACGCCCTCGGGCGTCACCCTCGCGCCGGAGGGTGGGGCGCACCAGTCGATCGGCACGCCGGCGATCGGCATG
ACCCAGCCCGGCCTCGCCGCCTTCGAGCCGGCCTTCGCCGACGAGCTGGCGGCGATCATGGAATGGGCGTTCGACCATCT
CCAGCGCGACGCCGCCGATCCGTATACCGATCCGCGCACCGGCCTCGCCGATGCGGCGGGCGGCTCGGTCTATCTGCGCC
TGTCGACCAACCCGGTCGAGCAGCCGGGCCGGCGCGGCACCGCCTGGCGGCAGGGGGCCACCGAGGGCGCCTACTGGCTG
CGCGAGCCGGGGCCGAACGCCGAACTCGTCATCGCCTATCAGGGGGTGGTGGCGCCGGAGGCGATCCGCGCCGCCGGGGC
GCTGGCGGAAAGCCGGCGCGATATCGGCGTGCTCGCCGTCACCTCGGCCGACCGGCTGCATGCCGGCTGGAGCGCGGCCC
AGCGGGCGAGATGCCGGGGCGAGGCGGTGACCTCGCTGGCCGAGCGCCTGCTCGCCCCGCTCCCGCGCGACTGCCGCATC
GTCACGGTGATCGACGGCCATCCCGCCACCCTGTCCTGGCTCGGCGGCGTCGCCGGCCATGCGGTGCTGCCGCTCGGCGT
CGAGCGCTTCGGCCAGACCGGCACCATCGCCGATCTCTACCGCGCCAACGGCATCGACGCCGCCGCGATCATCGAGCGCG
TCGGCACCTTCACCAGCGGCCGGCCGGTGCTGGCCTTTCCGGCCCGTCCGCGCGCCCGGTCCGGGGCGGCCGCGCTGGCG
GGGTGA

Upstream 100 bases:

>100_bases
ACTATCGCCACGATATTGCCCTGGGCCGCGCGAATCGCAAGGATTCGCTCCGCCCGCCCGCCTAGACTCGGCGCACCGCC
CTCACGCCGGGAGACCGCGA

Downstream 100 bases:

>100_bases
TGCCGGCGGGCTTGGCATCGGCCCGCATATCGTCCTACCTGCGGATCAGGAGGAGCGGCGATGACGGACTGGGACTGGCG
GCGCCCGCAAGGGCGGCATG

Product: transketolase, central region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 801; Mature: 800

Protein sequence:

>801_residues
MTPHLKTAEQRLLWLSHWMIHNANHLRPKVDGIKTGGHQASSASMVGIMAALYFTALRPEDRVAVKPHAAPVFHAMQYLM
GNTTRERLETFRGFGGTQSYPSRTKDDDDVDFSTGSVGLGVAITSFAALVQDYIAAKQWGRDVRRGRMVALMGDAEIDEG
NIHECLQEGWKNGLRDVWWVIDYNRQSLDGVAREGLWQRIEKIFEAFGWDVVRIKYGALQRAAFAEPGGEALRNWIDSCP
NQRYAALTFQGGAAWRKRLLDELGDQGAVSALIARRSDAELAALMENLGGNCVQTMADTFAAIDHDRPTCFLAYTIKGWG
TPIAGHKDNHGGVMTVEQMQAWQRHMGVGQGEEWERFAAVADVEGFRAWLDAVPFFAAGRRRHDDAHLPVPALASPGERE
ISTQAAFGRILDDLARGDSALAARILTTSPDVTGTTSLGPWVNRRRLFAREAMADLFRAEKIPSTARWDFAPEGQHLELG
IAETNLMLLLAAAGLARSLFGRRLIPIGTVYDPFIARGLDALNYACYQDARFLLVGTPSGVTLAPEGGAHQSIGTPAIGM
TQPGLAAFEPAFADELAAIMEWAFDHLQRDAADPYTDPRTGLADAAGGSVYLRLSTNPVEQPGRRGTAWRQGATEGAYWL
REPGPNAELVIAYQGVVAPEAIRAAGALAESRRDIGVLAVTSADRLHAGWSAAQRARCRGEAVTSLAERLLAPLPRDCRI
VTVIDGHPATLSWLGGVAGHAVLPLGVERFGQTGTIADLYRANGIDAAAIIERVGTFTSGRPVLAFPARPRARSGAAALA
G

Sequences:

>Translated_801_residues
MTPHLKTAEQRLLWLSHWMIHNANHLRPKVDGIKTGGHQASSASMVGIMAALYFTALRPEDRVAVKPHAAPVFHAMQYLM
GNTTRERLETFRGFGGTQSYPSRTKDDDDVDFSTGSVGLGVAITSFAALVQDYIAAKQWGRDVRRGRMVALMGDAEIDEG
NIHECLQEGWKNGLRDVWWVIDYNRQSLDGVAREGLWQRIEKIFEAFGWDVVRIKYGALQRAAFAEPGGEALRNWIDSCP
NQRYAALTFQGGAAWRKRLLDELGDQGAVSALIARRSDAELAALMENLGGNCVQTMADTFAAIDHDRPTCFLAYTIKGWG
TPIAGHKDNHGGVMTVEQMQAWQRHMGVGQGEEWERFAAVADVEGFRAWLDAVPFFAAGRRRHDDAHLPVPALASPGERE
ISTQAAFGRILDDLARGDSALAARILTTSPDVTGTTSLGPWVNRRRLFAREAMADLFRAEKIPSTARWDFAPEGQHLELG
IAETNLMLLLAAAGLARSLFGRRLIPIGTVYDPFIARGLDALNYACYQDARFLLVGTPSGVTLAPEGGAHQSIGTPAIGM
TQPGLAAFEPAFADELAAIMEWAFDHLQRDAADPYTDPRTGLADAAGGSVYLRLSTNPVEQPGRRGTAWRQGATEGAYWL
REPGPNAELVIAYQGVVAPEAIRAAGALAESRRDIGVLAVTSADRLHAGWSAAQRARCRGEAVTSLAERLLAPLPRDCRI
VTVIDGHPATLSWLGGVAGHAVLPLGVERFGQTGTIADLYRANGIDAAAIIERVGTFTSGRPVLAFPARPRARSGAAALA
G
>Mature_800_residues
TPHLKTAEQRLLWLSHWMIHNANHLRPKVDGIKTGGHQASSASMVGIMAALYFTALRPEDRVAVKPHAAPVFHAMQYLMG
NTTRERLETFRGFGGTQSYPSRTKDDDDVDFSTGSVGLGVAITSFAALVQDYIAAKQWGRDVRRGRMVALMGDAEIDEGN
IHECLQEGWKNGLRDVWWVIDYNRQSLDGVAREGLWQRIEKIFEAFGWDVVRIKYGALQRAAFAEPGGEALRNWIDSCPN
QRYAALTFQGGAAWRKRLLDELGDQGAVSALIARRSDAELAALMENLGGNCVQTMADTFAAIDHDRPTCFLAYTIKGWGT
PIAGHKDNHGGVMTVEQMQAWQRHMGVGQGEEWERFAAVADVEGFRAWLDAVPFFAAGRRRHDDAHLPVPALASPGEREI
STQAAFGRILDDLARGDSALAARILTTSPDVTGTTSLGPWVNRRRLFAREAMADLFRAEKIPSTARWDFAPEGQHLELGI
AETNLMLLLAAAGLARSLFGRRLIPIGTVYDPFIARGLDALNYACYQDARFLLVGTPSGVTLAPEGGAHQSIGTPAIGMT
QPGLAAFEPAFADELAAIMEWAFDHLQRDAADPYTDPRTGLADAAGGSVYLRLSTNPVEQPGRRGTAWRQGATEGAYWLR
EPGPNAELVIAYQGVVAPEAIRAAGALAESRRDIGVLAVTSADRLHAGWSAAQRARCRGEAVTSLAERLLAPLPRDCRIV
TVIDGHPATLSWLGGVAGHAVLPLGVERFGQTGTIADLYRANGIDAAAIIERVGTFTSGRPVLAFPARPRARSGAAALAG

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=611, Percent_Identity=25.3682487725041, Blast_Score=119, Evalue=6e-28,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 86786; Mature: 86655

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHLKTAEQRLLWLSHWMIHNANHLRPKVDGIKTGGHQASSASMVGIMAALYFTALRPE
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
DRVAVKPHAAPVFHAMQYLMGNTTRERLETFRGFGGTQSYPSRTKDDDDVDFSTGSVGLG
CCEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VAITSFAALVQDYIAAKQWGRDVRRGRMVALMGDAEIDEGNIHECLQEGWKNGLRDVWWV
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEE
IDYNRQSLDGVAREGLWQRIEKIFEAFGWDVVRIKYGALQRAAFAEPGGEALRNWIDSCP
EECCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCCCHHHHHHHHHHCC
NQRYAALTFQGGAAWRKRLLDELGDQGAVSALIARRSDAELAALMENLGGNCVQTMADTF
CCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHH
AAIDHDRPTCFLAYTIKGWGTPIAGHKDNHGGVMTVEQMQAWQRHMGVGQGEEWERFAAV
HHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHH
ADVEGFRAWLDAVPFFAAGRRRHDDAHLPVPALASPGEREISTQAAFGRILDDLARGDSA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHH
LAARILTTSPDVTGTTSLGPWVNRRRLFAREAMADLFRAEKIPSTARWDFAPEGQHLELG
HHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
IAETNLMLLLAAAGLARSLFGRRLIPIGTVYDPFIARGLDALNYACYQDARFLLVGTPSG
ECHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
VTLAPEGGAHQSIGTPAIGMTQPGLAAFEPAFADELAAIMEWAFDHLQRDAADPYTDPRT
CEECCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GLADAAGGSVYLRLSTNPVEQPGRRGTAWRQGATEGAYWLREPGPNAELVIAYQGVVAPE
CCCCCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCEEECCCCCCCEEEEEECCCCCHH
AIRAAGALAESRRDIGVLAVTSADRLHAGWSAAQRARCRGEAVTSLAERLLAPLPRDCRI
HHHHHHHHHHHCCCCEEEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VTVIDGHPATLSWLGGVAGHAVLPLGVERFGQTGTIADLYRANGIDAAAIIERVGTFTSG
EEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCC
RPVLAFPARPRARSGAAALAG
CCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TPHLKTAEQRLLWLSHWMIHNANHLRPKVDGIKTGGHQASSASMVGIMAALYFTALRPE
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
DRVAVKPHAAPVFHAMQYLMGNTTRERLETFRGFGGTQSYPSRTKDDDDVDFSTGSVGLG
CCEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VAITSFAALVQDYIAAKQWGRDVRRGRMVALMGDAEIDEGNIHECLQEGWKNGLRDVWWV
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEE
IDYNRQSLDGVAREGLWQRIEKIFEAFGWDVVRIKYGALQRAAFAEPGGEALRNWIDSCP
EECCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCCCHHHHHHHHHHCC
NQRYAALTFQGGAAWRKRLLDELGDQGAVSALIARRSDAELAALMENLGGNCVQTMADTF
CCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHH
AAIDHDRPTCFLAYTIKGWGTPIAGHKDNHGGVMTVEQMQAWQRHMGVGQGEEWERFAAV
HHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHH
ADVEGFRAWLDAVPFFAAGRRRHDDAHLPVPALASPGEREISTQAAFGRILDDLARGDSA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHH
LAARILTTSPDVTGTTSLGPWVNRRRLFAREAMADLFRAEKIPSTARWDFAPEGQHLELG
HHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
IAETNLMLLLAAAGLARSLFGRRLIPIGTVYDPFIARGLDALNYACYQDARFLLVGTPSG
ECHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
VTLAPEGGAHQSIGTPAIGMTQPGLAAFEPAFADELAAIMEWAFDHLQRDAADPYTDPRT
CEECCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GLADAAGGSVYLRLSTNPVEQPGRRGTAWRQGATEGAYWLREPGPNAELVIAYQGVVAPE
CCCCCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCEEECCCCCCCEEEEEECCCCCHH
AIRAAGALAESRRDIGVLAVTSADRLHAGWSAAQRARCRGEAVTSLAERLLAPLPRDCRI
HHHHHHHHHHHCCCCEEEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VTVIDGHPATLSWLGGVAGHAVLPLGVERFGQTGTIADLYRANGIDAAAIIERVGTFTSG
EEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCC
RPVLAFPARPRARSGAAALAG
CCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA