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The map label for this gene is ycgM [C]

Identifier: 148260956

GI number: 148260956

Start: 2152691

End: 2153536

Strand: Reverse

Name: ycgM [C]

Synonym: Acry_1963

Alternate gene names: 148260956

Gene position: 2153536-2152691 (Counterclockwise)

Preceding gene: 148260959

Following gene: 148260955

Centisome position: 63.54

GC content: 68.2

Gene sequence:

>846_bases
ATGAAACTGTTCAGGCATGGCGCCAGCGGCGCCGAACGTCCGGGAATTGTCGATGCCTCCGGCGCGCTGCGCGACCTCTC
CGGCGTCATTGCCGAAATCGACGCCACCGTTCTCTCCGATGCCGGGCTTGCGCGCCTCGCCGCGCTCGACGCCGCGACGC
TGCCGCTGGTGCCCGCCGGCACGCGGATCGGCGCGCCGGTTCCCCGGCCGGTCAATTTCATCTGCATCGGCCTCAACTAT
GCCGACCATGCGGCCGAATCCGGGCTCAAGGTGCCGGAGGAGCCGATCATCTTCCTCAAGGCCGGCAGCGCGTATTCGGG
CCCGAACGACGATATCGTGATCCCGCCCGGCTCGAAGGAGACGGACTGGGAGGTCGAACTCGGCGTGATCATCGGCACCG
GCGGCTCCCATATCGCCGAGGACGCGGCGCTCGATCACGTCGCCGGCTACTGCGTGGTCAACGATGTCAGCGAACGCGAA
TACCAGATCCGCCGCGGCGGCACGTGGGACAAGGGCAAGGGCTGCCCGAGCTTCGGCCCGACCGGCCCCTTCCTCGTCAC
CCGCGACGAGGTGCCCGATCCGCAGGCTCTCGATCTCTGGTGCGAGGTCGACGGCAAGCGGATGCAGAACGGCAACACGC
GGACGATGATCTTCGGCGTGAAGACGCTGGTCTCCTATGTCAGCCGCTTCATCCGGCTCGAACCCGGTGACATCATCGCC
ACCGGCACACCGCCCGGCGTCGGCATGGGCATCAAGCCTGAGCCGGTCTTCCTGCGGCCCGGCCAGACCGTGCGCCTCGG
CATCGCCGGGCTTGGCGAGCAGACGCAGAAGACGACCGGCGGCTGA

Upstream 100 bases:

>100_bases
GTCGATTATCCTGAACACATCACCGTCGTTTCGCCGCCCCTTGGCCCGCGCCGCCGCCGGGCCTAAAAGCGGTGCTCGAC
TATAATGGGAGTTTAAATAT

Downstream 100 bases:

>100_bases
TTCGCGCCCGGCATGACCGGAAAGGCCGGATTGCCCGGTGCCGCGCGCGGGCTGTATTGCACCCCGGCGGCACCGGGCCC
GGCCATCCGGACGCCGTGCC

Product: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKLFRHGASGAERPGIVDASGALRDLSGVIAEIDATVLSDAGLARLAALDAATLPLVPAGTRIGAPVPRPVNFICIGLNY
ADHAAESGLKVPEEPIIFLKAGSAYSGPNDDIVIPPGSKETDWEVELGVIIGTGGSHIAEDAALDHVAGYCVVNDVSERE
YQIRRGGTWDKGKGCPSFGPTGPFLVTRDEVPDPQALDLWCEVDGKRMQNGNTRTMIFGVKTLVSYVSRFIRLEPGDIIA
TGTPPGVGMGIKPEPVFLRPGQTVRLGIAGLGEQTQKTTGG

Sequences:

>Translated_281_residues
MKLFRHGASGAERPGIVDASGALRDLSGVIAEIDATVLSDAGLARLAALDAATLPLVPAGTRIGAPVPRPVNFICIGLNY
ADHAAESGLKVPEEPIIFLKAGSAYSGPNDDIVIPPGSKETDWEVELGVIIGTGGSHIAEDAALDHVAGYCVVNDVSERE
YQIRRGGTWDKGKGCPSFGPTGPFLVTRDEVPDPQALDLWCEVDGKRMQNGNTRTMIFGVKTLVSYVSRFIRLEPGDIIA
TGTPPGVGMGIKPEPVFLRPGQTVRLGIAGLGEQTQKTTGG
>Mature_281_residues
MKLFRHGASGAERPGIVDASGALRDLSGVIAEIDATVLSDAGLARLAALDAATLPLVPAGTRIGAPVPRPVNFICIGLNY
ADHAAESGLKVPEEPIIFLKAGSAYSGPNDDIVIPPGSKETDWEVELGVIIGTGGSHIAEDAALDHVAGYCVVNDVSERE
YQIRRGGTWDKGKGCPSFGPTGPFLVTRDEVPDPQALDLWCEVDGKRMQNGNTRTMIFGVKTLVSYVSRFIRLEPGDIIA
TGTPPGVGMGIKPEPVFLRPGQTVRLGIAGLGEQTQKTTGG

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=224, Percent_Identity=49.5535714285714, Blast_Score=224, Evalue=8e-59,
Organism=Homo sapiens, GI40786394, Length=224, Percent_Identity=48.2142857142857, Blast_Score=215, Evalue=4e-56,
Organism=Homo sapiens, GI13654274, Length=210, Percent_Identity=38.5714285714286, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI215422413, Length=210, Percent_Identity=38.0952380952381, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI66348062, Length=180, Percent_Identity=40.5555555555556, Blast_Score=145, Evalue=6e-35,
Organism=Escherichia coli, GI1787428, Length=189, Percent_Identity=35.978835978836, Blast_Score=117, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17557057, Length=177, Percent_Identity=38.4180790960452, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324161, Length=228, Percent_Identity=30.2631578947368, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28572127, Length=276, Percent_Identity=38.0434782608696, Blast_Score=175, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24663695, Length=247, Percent_Identity=31.5789473684211, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28571789, Length=203, Percent_Identity=34.9753694581281, Blast_Score=123, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 29464; Mature: 29464

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFRHGASGAERPGIVDASGALRDLSGVIAEIDATVLSDAGLARLAALDAATLPLVPAG
CCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEECCC
TRIGAPVPRPVNFICIGLNYADHAAESGLKVPEEPIIFLKAGSAYSGPNDDIVIPPGSKE
CCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCC
TDWEVELGVIIGTGGSHIAEDAALDHVAGYCVVNDVSEREYQIRRGGTWDKGKGCPSFGP
CCEEEEEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCC
TGPFLVTRDEVPDPQALDLWCEVDGKRMQNGNTRTMIFGVKTLVSYVSRFIRLEPGDIIA
CCCEEEECCCCCCCCEEEEEEECCCCEECCCCCEEEEEEHHHHHHHHHHHHEECCCCEEE
TGTPPGVGMGIKPEPVFLRPGQTVRLGIAGLGEQTQKTTGG
CCCCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCHHCCCC
>Mature Secondary Structure
MKLFRHGASGAERPGIVDASGALRDLSGVIAEIDATVLSDAGLARLAALDAATLPLVPAG
CCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEECCC
TRIGAPVPRPVNFICIGLNYADHAAESGLKVPEEPIIFLKAGSAYSGPNDDIVIPPGSKE
CCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCC
TDWEVELGVIIGTGGSHIAEDAALDHVAGYCVVNDVSEREYQIRRGGTWDKGKGCPSFGP
CCEEEEEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCC
TGPFLVTRDEVPDPQALDLWCEVDGKRMQNGNTRTMIFGVKTLVSYVSRFIRLEPGDIIA
CCCEEEECCCCCCCCEEEEEEECCCCEECCCCCEEEEEEHHHHHHHHHHHHEECCCCEEE
TGTPPGVGMGIKPEPVFLRPGQTVRLGIAGLGEQTQKTTGG
CCCCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA