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The map label for this gene is lktD [H]

Identifier: 148260890

GI number: 148260890

Start: 2093516

End: 2094946

Strand: Reverse

Name: lktD [H]

Synonym: Acry_1897

Alternate gene names: 148260890

Gene position: 2094946-2093516 (Counterclockwise)

Preceding gene: 148260891

Following gene: 148260889

Centisome position: 61.81

GC content: 69.74

Gene sequence:

>1431_bases
ATGCGCCGACCCCGACCCTCGCGCAAGGCGACTGACCGGCTGCCGCCCTCCGGCGGCAGCCTCGCCCTGGCCGATCCCGC
CTCGCTGTCGGACCTGCCGCTGCCGCTGCTGGAATTCCAGTCGCCGACGGCGGCGGTGATCGCGACGCCGGTGTCGATCG
TCTCGCGCTACACCATGCTGCTCGTCACCGCCCTGGTGGCGACGCTGATCGCCGTCGCGGCCGTCGTGCGCATTCCCAAG
GTGGTCTCGGCGCCCGGCCGGCTGGTCTCCACCGCCCCGAACGTCCTGCTCCAGCCCTTCGACACCTCGATCGTCCAGGC
GATCGACGTCCACGAGGGCGAGATCGTCCACAAGGGCGAGATCCTGGCGAAGCTGAACCCCACCTTCGCCAGCGCCAATC
TGCGCGCGCTGAGCGCCGAGGTGATCCAGCTCGCCGCCCGGCGCGACCGTCTCGCCGCCGAGGCGGGCGGCACCACCTAC
GCGCCGGCGCATCCCAACGCGGCGCAGCGTCTCCAGGCCGCGATCTTCCAGAGCCGCAAGGCCGAGCGCATCTACACGAT
CGAGAATTACGACCAGAAGATCGCCGAGCTGCGCATGATCATCGCCAAGAGCGACAGCGAGGCGGGGTTCTACCGCAAGC
AGGTCGGCGTGGCGAAGGATGTCGAGCACATGCGCGACCAGCTCCAGCGCATGCAGGTCGGCAGCAAGCTCAACTCCCTG
CTTGCCCGGAACGACCGGCTGACCGTGTCCAGCTCGCTCTCCAGCGCGCTGGCCACCGCCGCCGCCGGCGAGCGCGACCT
CGCCGCCCAGCAGGCCGAGCGCGACGCCTATGAAAAGAAATGGATCGCCGATGTCGGGGAGAAACTCGCCGAGACCGACA
GCAAGCTGATCGCCACCGAGCAGGACCTCGCCAAGGCGCGGCTGCAGAGCCAGCTCGTGGTGATGCGCGCGCCGCGCGAC
GCCATCGTGCTCACCGTCGCCCATGTCTCGGTCGGCTCGGTGCTGCGGTCGGGGGCCAAGTTCATCACCCTGGTGCCGCT
GGACGCCCCGCTCGAGGTCGAGGCCGATATCAGCGGCGCCGAATCCGGCCATGTCCATGTCGGCGATCCGGTCACGGTGA
AATTCGCCACCTTCGATTACCTGCGCTACGGCACCGCCCGCGGCACGCTCCGTTCGGTCAGCGCCGACAGTTTCAGCTCC
GACCAGCCGCCGGCGGAGGGCGCCTCGCCGCTGCCCAACCGGCCGCGCGGCCTCTACTACAAGGCCCGCATCTCGATCGA
CAGGCTGATGCTGCACGGCGTGCCGCCCAGCTTCCGCCTCACCCCCGGCATGCCGCTCACCGCCGACATCAAGACCGGCC
GGCGCACCATCCTCTCCTATTTCATGACCAAGCTGCTGCCGGTCGCGACCGACAGCATGCGCGAGCCCTGA

Upstream 100 bases:

>100_bases
GTCGATATCGGCCGGCACGCCGATCTCGTCGAGCGTTGCGCGATCTACCGCCATCTCTGGCTCCAGCAGAACCGCCACAT
GAATCCCGAAGGAGGCCGCC

Downstream 100 bases:

>100_bases
GGGGGGCATCCCGCGCCGATGCGACTGCTGGACCATCTGGCGGCGCTTTCGCCGCCCAGGGCCCTCCGCCGGGCGCGGCG
CCTCGCCGCCGCCGGCGCGC

Product: HlyD family type I secretion membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MRRPRPSRKATDRLPPSGGSLALADPASLSDLPLPLLEFQSPTAAVIATPVSIVSRYTMLLVTALVATLIAVAAVVRIPK
VVSAPGRLVSTAPNVLLQPFDTSIVQAIDVHEGEIVHKGEILAKLNPTFASANLRALSAEVIQLAARRDRLAAEAGGTTY
APAHPNAAQRLQAAIFQSRKAERIYTIENYDQKIAELRMIIAKSDSEAGFYRKQVGVAKDVEHMRDQLQRMQVGSKLNSL
LARNDRLTVSSSLSSALATAAAGERDLAAQQAERDAYEKKWIADVGEKLAETDSKLIATEQDLAKARLQSQLVVMRAPRD
AIVLTVAHVSVGSVLRSGAKFITLVPLDAPLEVEADISGAESGHVHVGDPVTVKFATFDYLRYGTARGTLRSVSADSFSS
DQPPAEGASPLPNRPRGLYYKARISIDRLMLHGVPPSFRLTPGMPLTADIKTGRRTILSYFMTKLLPVATDSMREP

Sequences:

>Translated_476_residues
MRRPRPSRKATDRLPPSGGSLALADPASLSDLPLPLLEFQSPTAAVIATPVSIVSRYTMLLVTALVATLIAVAAVVRIPK
VVSAPGRLVSTAPNVLLQPFDTSIVQAIDVHEGEIVHKGEILAKLNPTFASANLRALSAEVIQLAARRDRLAAEAGGTTY
APAHPNAAQRLQAAIFQSRKAERIYTIENYDQKIAELRMIIAKSDSEAGFYRKQVGVAKDVEHMRDQLQRMQVGSKLNSL
LARNDRLTVSSSLSSALATAAAGERDLAAQQAERDAYEKKWIADVGEKLAETDSKLIATEQDLAKARLQSQLVVMRAPRD
AIVLTVAHVSVGSVLRSGAKFITLVPLDAPLEVEADISGAESGHVHVGDPVTVKFATFDYLRYGTARGTLRSVSADSFSS
DQPPAEGASPLPNRPRGLYYKARISIDRLMLHGVPPSFRLTPGMPLTADIKTGRRTILSYFMTKLLPVATDSMREP
>Mature_476_residues
MRRPRPSRKATDRLPPSGGSLALADPASLSDLPLPLLEFQSPTAAVIATPVSIVSRYTMLLVTALVATLIAVAAVVRIPK
VVSAPGRLVSTAPNVLLQPFDTSIVQAIDVHEGEIVHKGEILAKLNPTFASANLRALSAEVIQLAARRDRLAAEAGGTTY
APAHPNAAQRLQAAIFQSRKAERIYTIENYDQKIAELRMIIAKSDSEAGFYRKQVGVAKDVEHMRDQLQRMQVGSKLNSL
LARNDRLTVSSSLSSALATAAAGERDLAAQQAERDAYEKKWIADVGEKLAETDSKLIATEQDLAKARLQSQLVVMRAPRD
AIVLTVAHVSVGSVLRSGAKFITLVPLDAPLEVEADISGAESGHVHVGDPVTVKFATFDYLRYGTARGTLRSVSADSFSS
DQPPAEGASPLPNRPRGLYYKARISIDRLMLHGVPPSFRLTPGMPLTADIKTGRRTILSYFMTKLLPVATDSMREP

Specific function: Involved in the transport of the Leukotoxin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 51331; Mature: 51331

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPRPSRKATDRLPPSGGSLALADPASLSDLPLPLLEFQSPTAAVIATPVSIVSRYTML
CCCCCCCCCHHCCCCCCCCCEEEECCCCCCCCCCHHHHCCCCCHHHHCCHHHHHHHHHHH
LVTALVATLIAVAAVVRIPKVVSAPGRLVSTAPNVLLQPFDTSIVQAIDVHEGEIVHKGE
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCEECCCCHHHHHHHCCCCCCEEECCC
ILAKLNPTFASANLRALSAEVIQLAARRDRLAAEAGGTTYAPAHPNAAQRLQAAIFQSRK
EEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
AERIYTIENYDQKIAELRMIIAKSDSEAGFYRKQVGVAKDVEHMRDQLQRMQVGSKLNSL
CCEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LARNDRLTVSSSLSSALATAAAGERDLAAQQAERDAYEKKWIADVGEKLAETDSKLIATE
HHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECH
QDLAKARLQSQLVVMRAPRDAIVLTVAHVSVGSVLRSGAKFITLVPLDAPLEVEADISGA
HHHHHHHHHHCEEEEECCCCEEEEEEHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCC
ESGHVHVGDPVTVKFATFDYLRYGTARGTLRSVSADSFSSDQPPAEGASPLPNRPRGLYY
CCCCEECCCCEEEEEEEHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEE
KARISIDRLMLHGVPPSFRLTPGMPLTADIKTGRRTILSYFMTKLLPVATDSMREP
EEEECHHHHHHHCCCCCCEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRRPRPSRKATDRLPPSGGSLALADPASLSDLPLPLLEFQSPTAAVIATPVSIVSRYTML
CCCCCCCCCHHCCCCCCCCCEEEECCCCCCCCCCHHHHCCCCCHHHHCCHHHHHHHHHHH
LVTALVATLIAVAAVVRIPKVVSAPGRLVSTAPNVLLQPFDTSIVQAIDVHEGEIVHKGE
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCEECCCCHHHHHHHCCCCCCEEECCC
ILAKLNPTFASANLRALSAEVIQLAARRDRLAAEAGGTTYAPAHPNAAQRLQAAIFQSRK
EEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
AERIYTIENYDQKIAELRMIIAKSDSEAGFYRKQVGVAKDVEHMRDQLQRMQVGSKLNSL
CCEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LARNDRLTVSSSLSSALATAAAGERDLAAQQAERDAYEKKWIADVGEKLAETDSKLIATE
HHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECH
QDLAKARLQSQLVVMRAPRDAIVLTVAHVSVGSVLRSGAKFITLVPLDAPLEVEADISGA
HHHHHHHHHHCEEEEECCCCEEEEEEHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCC
ESGHVHVGDPVTVKFATFDYLRYGTARGTLRSVSADSFSSDQPPAEGASPLPNRPRGLYY
CCCCEECCCCEEEEEEEHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEE
KARISIDRLMLHGVPPSFRLTPGMPLTADIKTGRRTILSYFMTKLLPVATDSMREP
EEEECHHHHHHHCCCCCCEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040588; 2914876; 2707120 [H]