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The map label for this gene is clpB [H]

Identifier: 148260817

GI number: 148260817

Start: 2013473

End: 2016055

Strand: Reverse

Name: clpB [H]

Synonym: Acry_1823

Alternate gene names: 148260817

Gene position: 2016055-2013473 (Counterclockwise)

Preceding gene: 148260825

Following gene: 148260815

Centisome position: 59.48

GC content: 66.28

Gene sequence:

>2583_bases
ATGGATTTCGAGAAGTTTACCGAACGCGCCCGCGGCTTCGTGCAGGCCGCGCAGACGATTGCCGTGCGCGAATATCACCA
GCAGATCACGCCGGAACACCTGCTCAAGGCGTTTCTCGACGATGAGGAAGGGGCCGCGAGCGGGCTGATCCGCGCGGCCG
GGGGCGATCCGGCCGCGGTTCGTCTCGCGGCCGATGCCGCGATTGGAAAACTGCCGAAGGTGCAGGGCTCCGGCGCCGGG
CAGCCGCAGATCACGCCCGATCTCGTGCGGGTGCTCGATGCGGCGCAGCAGATGGCGCAGAAGGCCGGCGATGAATATGT
CGCGCAGGACCGCGTGCTGGTGGCACTCGCGGCGAGCGGCACGCCGGCGGGCCGGGCGCTGACCGCGGCCGGCGCCTCGG
CGCAGGCCCTGGAGAAGGCGGTGGCCGATATCCGCAAGGGCCGCACGGTGACGAGCGCGAACGCGGAGCAGACCTTCGAT
GCGCTGAAGAAATATGCGCGGGATGTGACCGAGGCCGCGCGCGCGCAGAAGCTTGATCCGGTGATCGGCCGCGACGAGGA
GATCCGCCGGGCGATCCAGGTGCTGGCGCGGCGGACCAAGAACAACCCGGTGCTCATCGGCGAGCCTGGGGTTGGCAAGA
CGGCGATCGTCGAGGGGCTCGCGCTCCGCATCGTCAATGGCGACGTGCCGGAGGCGCTGAAGGGCAAGCGGCTGCTCGCG
CTCGATCTCGGCGCGATGGTGGCCGGCGCGAAATATCGCGGCGAGTTCGAGGAACGGCTGAAAGCCGTGCTGAAGGAGAT
CGAAGGCTCGAACGGCGAGGTCATCCTGTTCATCGACGAGATGCACACGCTGGTCGGCGCGGGGCGGGCGGATGGCGCGA
TGGATGCCTCGAACCTGATCAAGCCCGAACTGGCTCGCGGCGCGCTGCACTGCGTGGGGGCGACGACGCTCGACGAGTAT
CGGAAGTACATCGAGAAGGATGCGGCGCTGGCGCGGCGCTTCCAGCCGGTCTTCGTGGATGAGCCGAGTGTCGAGGACAC
GATCTCGATCCTGCGCGGGATCAAGGAGAAATACGAACTTCATCACGGCGTGCGGATTTCGGATTCGGCGCTGGTGGCGG
CGGCGACCCTGTCCAACCGCTACATTACTGACCGGTTCCTGCCGGACAAGGCGATCGACCTTGTCGACGAGGCCGCCTCG
CGCCTGCGGATGCAGGTGGATTCCAAGCCCGAGGCGCTCGATGAACTCGATCGGCGGCTGATGCAGCTCAAGATCGAACG
GGAAGCGCTGCGCAAGGAGCAGGATCCCGCCTCGAAGGAACGGCTGGAGCGGCTGGAGGGTGAAATCGCCGAACTCGAGG
AGAAATCCGACGCGATGACGGCGGCGTGGAAGGCCGAAAAGGACCGACTGAATGCCACGCAAAAGCTGAAGGAGCAGCTC
GATCAGGCGCGGGGCGAGGCGGAGATGGCGCAGCGCTCCGGCAATCTGACCCGGGCCTCGGAGCTGATGTATGGCGTGAT
CCCCGAGATCGAGCGGAAGCTCGCCGCCGGGCCGACGGAAGGAGCCATGGTCAACGAGGCGGTCACCGAAGCGCAGATCG
CCCAGGTGGTGGCCCGCTGGACCGGCATTCCGGTCGACCGGATGCTGGAGGGCGAGCGCGCCAAGCTCATCAGGATGGAA
GAGGAGTTGCGCAAGCGCGTGGTGGGCCAGGAAGCCGCGCTGCGGGCGGTTTCGGATGCCGTGCGCCGGGCACGGGCCGG
GTTGCAGGATCCGAACCGACCGATCGGCTCCTTCCTGTTCCTGGGCCCGACCGGCGTCGGCAAGACCGAAACCTGCAAGG
CGCTGGCCGAGTTTCTGTTCGACGATGAGCGGGCGATGGTGCGCATCGACATGAGCGAATTCATGGAGAAGCACGCCGTG
GCCCGGCTGATCGGCGCGCCGCCAGGCTATGTCGGCTACGAGGAAGGCGGGGTGCTCACCGAAGCCGTGCGGCGCCGGCC
GTATCAGGTGATCCTATTCGACGAGGTCGAGAAGGCGCACGAGGATGTCTTCAACGTCTTGTTGCAGGTGCTTGATGATG
GCCGACTGACCGACGGACAGGGGCGCACGGTCGACTTCAAGAACACGATCATCGTGCTCACGTCGAACCTGGGCAGCGAG
GTGCTCGCCGCTCAGCCTGAAGGCGAGGATGTCGTATTGGCCGAACCGCAGGTGATGCGGGTGGTCCGCCAGCATTTCCG
GCCGGAATTCCTGAACCGGCTGGACGAGATCATCCTGTTCCGGCGCCTGCAGCGCGCCGATATGGCACGGATCGTCGAAA
TTCAGTTGAGGCATCTGGAATCGCTTCTCGCAGACCGGAAGATCACCCTGCATCTCGATCAGGCGGCGCGGGACTGGCTG
GCGAACGAGGGATACGACCCGGTCTACGGGGCACGGCCGCTGAAGCGGGTGATTCAGCGTTCGCTGCAGAACAAGCTGGC
GACGAGGCTCCTCGAAGGGGCCATCCATGACGGCGAGACGGTGAATGTGACCATCGACGATGACGGTCTCTCGATTGCCG
GCGGGCTCGCGGCGGCAGCCTGA

Upstream 100 bases:

>100_bases
AGGAGGATCAATGCAGCAACCATGTCCAGCGGACAAGGTCGGACCATTGCCTTGCGAGGGATGGTCCGGCCGGGTCGCCT
GATGAAAGGGATCGAGAACA

Downstream 100 bases:

>100_bases
GAGCGTGGCAACAGCCCGGCCCATGCGGATTGTTCATGGCCGGGCTGCTTGCCGGAAAATTACGCCATCTCGCAGATGCG
AAATGGACGAATTTCAAAAA

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 860; Mature: 860

Protein sequence:

>860_residues
MDFEKFTERARGFVQAAQTIAVREYHQQITPEHLLKAFLDDEEGAASGLIRAAGGDPAAVRLAADAAIGKLPKVQGSGAG
QPQITPDLVRVLDAAQQMAQKAGDEYVAQDRVLVALAASGTPAGRALTAAGASAQALEKAVADIRKGRTVTSANAEQTFD
ALKKYARDVTEAARAQKLDPVIGRDEEIRRAIQVLARRTKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPEALKGKRLLA
LDLGAMVAGAKYRGEFEERLKAVLKEIEGSNGEVILFIDEMHTLVGAGRADGAMDASNLIKPELARGALHCVGATTLDEY
RKYIEKDAALARRFQPVFVDEPSVEDTISILRGIKEKYELHHGVRISDSALVAAATLSNRYITDRFLPDKAIDLVDEAAS
RLRMQVDSKPEALDELDRRLMQLKIEREALRKEQDPASKERLERLEGEIAELEEKSDAMTAAWKAEKDRLNATQKLKEQL
DQARGEAEMAQRSGNLTRASELMYGVIPEIERKLAAGPTEGAMVNEAVTEAQIAQVVARWTGIPVDRMLEGERAKLIRME
EELRKRVVGQEAALRAVSDAVRRARAGLQDPNRPIGSFLFLGPTGVGKTETCKALAEFLFDDERAMVRIDMSEFMEKHAV
ARLIGAPPGYVGYEEGGVLTEAVRRRPYQVILFDEVEKAHEDVFNVLLQVLDDGRLTDGQGRTVDFKNTIIVLTSNLGSE
VLAAQPEGEDVVLAEPQVMRVVRQHFRPEFLNRLDEIILFRRLQRADMARIVEIQLRHLESLLADRKITLHLDQAARDWL
ANEGYDPVYGARPLKRVIQRSLQNKLATRLLEGAIHDGETVNVTIDDDGLSIAGGLAAAA

Sequences:

>Translated_860_residues
MDFEKFTERARGFVQAAQTIAVREYHQQITPEHLLKAFLDDEEGAASGLIRAAGGDPAAVRLAADAAIGKLPKVQGSGAG
QPQITPDLVRVLDAAQQMAQKAGDEYVAQDRVLVALAASGTPAGRALTAAGASAQALEKAVADIRKGRTVTSANAEQTFD
ALKKYARDVTEAARAQKLDPVIGRDEEIRRAIQVLARRTKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPEALKGKRLLA
LDLGAMVAGAKYRGEFEERLKAVLKEIEGSNGEVILFIDEMHTLVGAGRADGAMDASNLIKPELARGALHCVGATTLDEY
RKYIEKDAALARRFQPVFVDEPSVEDTISILRGIKEKYELHHGVRISDSALVAAATLSNRYITDRFLPDKAIDLVDEAAS
RLRMQVDSKPEALDELDRRLMQLKIEREALRKEQDPASKERLERLEGEIAELEEKSDAMTAAWKAEKDRLNATQKLKEQL
DQARGEAEMAQRSGNLTRASELMYGVIPEIERKLAAGPTEGAMVNEAVTEAQIAQVVARWTGIPVDRMLEGERAKLIRME
EELRKRVVGQEAALRAVSDAVRRARAGLQDPNRPIGSFLFLGPTGVGKTETCKALAEFLFDDERAMVRIDMSEFMEKHAV
ARLIGAPPGYVGYEEGGVLTEAVRRRPYQVILFDEVEKAHEDVFNVLLQVLDDGRLTDGQGRTVDFKNTIIVLTSNLGSE
VLAAQPEGEDVVLAEPQVMRVVRQHFRPEFLNRLDEIILFRRLQRADMARIVEIQLRHLESLLADRKITLHLDQAARDWL
ANEGYDPVYGARPLKRVIQRSLQNKLATRLLEGAIHDGETVNVTIDDDGLSIAGGLAAAA
>Mature_860_residues
MDFEKFTERARGFVQAAQTIAVREYHQQITPEHLLKAFLDDEEGAASGLIRAAGGDPAAVRLAADAAIGKLPKVQGSGAG
QPQITPDLVRVLDAAQQMAQKAGDEYVAQDRVLVALAASGTPAGRALTAAGASAQALEKAVADIRKGRTVTSANAEQTFD
ALKKYARDVTEAARAQKLDPVIGRDEEIRRAIQVLARRTKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPEALKGKRLLA
LDLGAMVAGAKYRGEFEERLKAVLKEIEGSNGEVILFIDEMHTLVGAGRADGAMDASNLIKPELARGALHCVGATTLDEY
RKYIEKDAALARRFQPVFVDEPSVEDTISILRGIKEKYELHHGVRISDSALVAAATLSNRYITDRFLPDKAIDLVDEAAS
RLRMQVDSKPEALDELDRRLMQLKIEREALRKEQDPASKERLERLEGEIAELEEKSDAMTAAWKAEKDRLNATQKLKEQL
DQARGEAEMAQRSGNLTRASELMYGVIPEIERKLAAGPTEGAMVNEAVTEAQIAQVVARWTGIPVDRMLEGERAKLIRME
EELRKRVVGQEAALRAVSDAVRRARAGLQDPNRPIGSFLFLGPTGVGKTETCKALAEFLFDDERAMVRIDMSEFMEKHAV
ARLIGAPPGYVGYEEGGVLTEAVRRRPYQVILFDEVEKAHEDVFNVLLQVLDDGRLTDGQGRTVDFKNTIIVLTSNLGSE
VLAAQPEGEDVVLAEPQVMRVVRQHFRPEFLNRLDEIILFRRLQRADMARIVEIQLRHLESLLADRKITLHLDQAARDWL
ANEGYDPVYGARPLKRVIQRSLQNKLATRLLEGAIHDGETVNVTIDDDGLSIAGGLAAAA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=357, Percent_Identity=36.1344537815126, Blast_Score=217, Evalue=3e-56,
Organism=Escherichia coli, GI1788943, Length=853, Percent_Identity=59.6717467760844, Blast_Score=1009, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=404, Percent_Identity=42.5742574257426, Blast_Score=282, Evalue=8e-77,
Organism=Saccharomyces cerevisiae, GI6320464, Length=701, Percent_Identity=56.0627674750357, Blast_Score=799, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=866, Percent_Identity=44.3418013856813, Blast_Score=702, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 94392; Mature: 94392

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFEKFTERARGFVQAAQTIAVREYHQQITPEHLLKAFLDDEEGAASGLIRAAGGDPAAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHCEEEECCCCCCEE
RLAADAAIGKLPKVQGSGAGQPQITPDLVRVLDAAQQMAQKAGDEYVAQDRVLVALAASG
EEEHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEECCC
TPAGRALTAAGASAQALEKAVADIRKGRTVTSANAEQTFDALKKYARDVTEAARAQKLDP
CCCCCCHHHCCCHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VIGRDEEIRRAIQVLARRTKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPEALKGKRLLA
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHEEECCCCCHHHCCCEEEE
LDLGAMVAGAKYRGEFEERLKAVLKEIEGSNGEVILFIDEMHTLVGAGRADGAMDASNLI
EEHHHHHHCCHHCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHCC
KPELARGALHCVGATTLDEYRKYIEKDAALARRFQPVFVDEPSVEDTISILRGIKEKYEL
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
HHGVRISDSALVAAATLSNRYITDRFLPDKAIDLVDEAASRLRMQVDSKPEALDELDRRL
HCCCEECCCHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MQLKIEREALRKEQDPASKERLERLEGEIAELEEKSDAMTAAWKAEKDRLNATQKLKEQL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DQARGEAEMAQRSGNLTRASELMYGVIPEIERKLAAGPTEGAMVNEAVTEAQIAQVVARW
HHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TGIPVDRMLEGERAKLIRMEEELRKRVVGQEAALRAVSDAVRRARAGLQDPNRPIGSFLF
CCCCHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LGPTGVGKTETCKALAEFLFDDERAMVRIDMSEFMEKHAVARLIGAPPGYVGYEEGGVLT
ECCCCCCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
EAVRRRPYQVILFDEVEKAHEDVFNVLLQVLDDGRLTDGQGRTVDFKNTIIVLTSNLGSE
HHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCCCH
VLAAQPEGEDVVLAEPQVMRVVRQHFRPEFLNRLDEIILFRRLQRADMARIVEIQLRHLE
HEECCCCCCEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLADRKITLHLDQAARDWLANEGYDPVYGARPLKRVIQRSLQNKLATRLLEGAIHDGET
HHHHCCEEEEEECHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VNVTIDDDGLSIAGGLAAAA
EEEEECCCCCEECCCHHHCC
>Mature Secondary Structure
MDFEKFTERARGFVQAAQTIAVREYHQQITPEHLLKAFLDDEEGAASGLIRAAGGDPAAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHCEEEECCCCCCEE
RLAADAAIGKLPKVQGSGAGQPQITPDLVRVLDAAQQMAQKAGDEYVAQDRVLVALAASG
EEEHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEECCC
TPAGRALTAAGASAQALEKAVADIRKGRTVTSANAEQTFDALKKYARDVTEAARAQKLDP
CCCCCCHHHCCCHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VIGRDEEIRRAIQVLARRTKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPEALKGKRLLA
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHEEECCCCCHHHCCCEEEE
LDLGAMVAGAKYRGEFEERLKAVLKEIEGSNGEVILFIDEMHTLVGAGRADGAMDASNLI
EEHHHHHHCCHHCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHCC
KPELARGALHCVGATTLDEYRKYIEKDAALARRFQPVFVDEPSVEDTISILRGIKEKYEL
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
HHGVRISDSALVAAATLSNRYITDRFLPDKAIDLVDEAASRLRMQVDSKPEALDELDRRL
HCCCEECCCHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MQLKIEREALRKEQDPASKERLERLEGEIAELEEKSDAMTAAWKAEKDRLNATQKLKEQL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DQARGEAEMAQRSGNLTRASELMYGVIPEIERKLAAGPTEGAMVNEAVTEAQIAQVVARW
HHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TGIPVDRMLEGERAKLIRMEEELRKRVVGQEAALRAVSDAVRRARAGLQDPNRPIGSFLF
CCCCHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LGPTGVGKTETCKALAEFLFDDERAMVRIDMSEFMEKHAVARLIGAPPGYVGYEEGGVLT
ECCCCCCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
EAVRRRPYQVILFDEVEKAHEDVFNVLLQVLDDGRLTDGQGRTVDFKNTIIVLTSNLGSE
HHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCCCH
VLAAQPEGEDVVLAEPQVMRVVRQHFRPEFLNRLDEIILFRRLQRADMARIVEIQLRHLE
HEECCCCCCEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLADRKITLHLDQAARDWLANEGYDPVYGARPLKRVIQRSLQNKLATRLLEGAIHDGET
HHHHCCEEEEEECHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VNVTIDDDGLSIAGGLAAAA
EEEEECCCCCEECCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]