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The map label for this gene is mtaD [H]

Identifier: 148260741

GI number: 148260741

Start: 1925167

End: 1926537

Strand: Reverse

Name: mtaD [H]

Synonym: Acry_1745

Alternate gene names: 148260741

Gene position: 1926537-1925167 (Counterclockwise)

Preceding gene: 148260746

Following gene: 148260739

Centisome position: 56.84

GC content: 74.76

Gene sequence:

>1371_bases
ATGCGGCGACTCTGGCTCGAACAGGCTTTTCTCCCCGAAGGATGGGCATCCGGCGTCGCGCTCGACATCGACGGGTCCGG
CCGCATCGCCGGCCTCGCCGCGAATGCCCCGCCGGCCGATCGCGAAACCGTCCCCGGCTGCGTGCTGCCCGGCCTGCCCA
ACCTGCACAGCCACGGCTTCCAGCGGGCGATGTCCGCGCTCGCCCAGCGCCGCCGCGCCGCCGCCGAGGATTTCTGGTCC
TGGCGCGGCGTGATGTACCGCACCGCCCTCGCGCTGCCGCCGGACGACATCGCCGCCGTCACCGCCATGGCCTTCATGGA
AATGCTCGAGCGCGGCTTCACCGCGGTCGCCGAATTCCATTACCTGCACAACGATTCCGCCGGCGCCCCCTATGCCGATC
CCGCCGAGCTCGCCACGCGGGTGATCGAGGCGGCGGCGCAAACCGGCATCGGCCTCACCCTGCTGCCGGTGCTCTACAGC
GCCGCAGGCCCCAACCGCCCGCCCGAGCCGGGCCAGCGCCGCTTCATCACCGATCTCGACGGGTTTCTGCGCCTGCACGC
GGCCACGGCGGAACGGCTGCGCGCCCTGCCGGGCGCCGTGCTCGGCGCCGCGCCGCACTCGCTGCGCGCCGCCCGCGCCG
CCGATGTCGCCGCCCTGTCCGGCCTGCTTCCCGAAGGCCCGCTCCACATCCACGCCGCCGAGCAGACCGGCGAGGTCGCC
GAGGTCGAGGCCGCGCTCGGCGCCCGCCCGGTCGAATTCCTGCTCCGCGAGGCGGGGGTCGACGCCCGCTGGTGCCTGAT
CCACGCCACCCACATGGCGGCCGAGGAAACCGCCGGCCTCGCCCGCGCCGGCGCCGTCGCCGGCCTCTGCCCGATCACCG
AGGCCGATCTCGGCGACGGCATCTTCAATGGAAACACCTTCATCGATGCCGGCGGGCGTTTCGGCGTCGGCACCGATTCG
AATGTCGCGATCGAGGCCCCCGCCGAGCTGCGCCAGCTCGAATGGAGCCAGCGCCTGCGCGACCGTCGCCGCCTCGTCCT
CGCCGACCCGGCGCGCGACGGCGGTTCGACCGGCGCCGCCCTCTACCGTGCGGCCCTCGCCGGCGGCGCGCAGGCCCTGG
CCCAGCCCATCGGCGCCATCGCCCCCGGCTGCCGCGCCGATCTCGTCTCGCTCCGCCGCGCCGGCACCGACCTCGCCGCG
CTCTCCGCCGAAACCCGGCTCGATCACTACATCTTCGCCGGCGGCGCGCGGCTGGTCGACCGTGTCTACGTCGCCGGGCG
CTGCCTTGTGCGCGAAGGCCGGCACGATGCCCGCGCCGCCATCGAATCCCGCTTCGCCGCGGCCCTCCGCCGCCTGGAGG
ACGCGCTCTGA

Upstream 100 bases:

>100_bases
CAGCCGGTCGCATCGCATGATACCCTCCTGACAACGCCGAACAAAATGTATATACAACTAGCCGAACGACGATGGCAACC
CATTCCCGAAAGGACCGACC

Downstream 100 bases:

>100_bases
ACTTGTATGTACAATCTCAGCCCGGCTGGCCGCCATCCTCGCGGATCAGCGCCAGCCGGCGATAGAGCGTGTTGCGGCTG
ATCCCGAGCCGCCGCGCCGC

Product: N-formimino-L-glutamate deiminase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MRRLWLEQAFLPEGWASGVALDIDGSGRIAGLAANAPPADRETVPGCVLPGLPNLHSHGFQRAMSALAQRRRAAAEDFWS
WRGVMYRTALALPPDDIAAVTAMAFMEMLERGFTAVAEFHYLHNDSAGAPYADPAELATRVIEAAAQTGIGLTLLPVLYS
AAGPNRPPEPGQRRFITDLDGFLRLHAATAERLRALPGAVLGAAPHSLRAARAADVAALSGLLPEGPLHIHAAEQTGEVA
EVEAALGARPVEFLLREAGVDARWCLIHATHMAAEETAGLARAGAVAGLCPITEADLGDGIFNGNTFIDAGGRFGVGTDS
NVAIEAPAELRQLEWSQRLRDRRRLVLADPARDGGSTGAALYRAALAGGAQALAQPIGAIAPGCRADLVSLRRAGTDLAA
LSAETRLDHYIFAGGARLVDRVYVAGRCLVREGRHDARAAIESRFAAALRRLEDAL

Sequences:

>Translated_456_residues
MRRLWLEQAFLPEGWASGVALDIDGSGRIAGLAANAPPADRETVPGCVLPGLPNLHSHGFQRAMSALAQRRRAAAEDFWS
WRGVMYRTALALPPDDIAAVTAMAFMEMLERGFTAVAEFHYLHNDSAGAPYADPAELATRVIEAAAQTGIGLTLLPVLYS
AAGPNRPPEPGQRRFITDLDGFLRLHAATAERLRALPGAVLGAAPHSLRAARAADVAALSGLLPEGPLHIHAAEQTGEVA
EVEAALGARPVEFLLREAGVDARWCLIHATHMAAEETAGLARAGAVAGLCPITEADLGDGIFNGNTFIDAGGRFGVGTDS
NVAIEAPAELRQLEWSQRLRDRRRLVLADPARDGGSTGAALYRAALAGGAQALAQPIGAIAPGCRADLVSLRRAGTDLAA
LSAETRLDHYIFAGGARLVDRVYVAGRCLVREGRHDARAAIESRFAAALRRLEDAL
>Mature_456_residues
MRRLWLEQAFLPEGWASGVALDIDGSGRIAGLAANAPPADRETVPGCVLPGLPNLHSHGFQRAMSALAQRRRAAAEDFWS
WRGVMYRTALALPPDDIAAVTAMAFMEMLERGFTAVAEFHYLHNDSAGAPYADPAELATRVIEAAAQTGIGLTLLPVLYS
AAGPNRPPEPGQRRFITDLDGFLRLHAATAERLRALPGAVLGAAPHSLRAARAADVAALSGLLPEGPLHIHAAEQTGEVA
EVEAALGARPVEFLLREAGVDARWCLIHATHMAAEETAGLARAGAVAGLCPITEADLGDGIFNGNTFIDAGGRFGVGTDS
NVAIEAPAELRQLEWSQRLRDRRRLVLADPARDGGSTGAALYRAALAGGAQALAQPIGAIAPGCRADLVSLRRAGTDLAA
LSAETRLDHYIFAGGARLVDRVYVAGRCLVREGRHDARAAIESRFAAALRRLEDAL

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540282, Length=435, Percent_Identity=28.0459770114943, Blast_Score=174, Evalue=6e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 48108; Mature: 48108

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLWLEQAFLPEGWASGVALDIDGSGRIAGLAANAPPADRETVPGCVLPGLPNLHSHGF
CCCHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHH
QRAMSALAQRRRAAAEDFWSWRGVMYRTALALPPDDIAAVTAMAFMEMLERGFTAVAEFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YLHNDSAGAPYADPAELATRVIEAAAQTGIGLTLLPVLYSAAGPNRPPEPGQRRFITDLD
HHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
GFLRLHAATAERLRALPGAVLGAAPHSLRAARAADVAALSGLLPEGPLHIHAAEQTGEVA
HHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHH
EVEAALGARPVEFLLREAGVDARWCLIHATHMAAEETAGLARAGAVAGLCPITEADLGDG
HHHHHHCCCHHHHHHHHCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IFNGNTFIDAGGRFGVGTDSNVAIEAPAELRQLEWSQRLRDRRRLVLADPARDGGSTGAA
EECCCEEEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHH
LYRAALAGGAQALAQPIGAIAPGCRADLVSLRRAGTDLAALSAETRLDHYIFAGGARLVD
HHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHEEECHHHHHH
RVYVAGRCLVREGRHDARAAIESRFAAALRRLEDAL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRLWLEQAFLPEGWASGVALDIDGSGRIAGLAANAPPADRETVPGCVLPGLPNLHSHGF
CCCHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHH
QRAMSALAQRRRAAAEDFWSWRGVMYRTALALPPDDIAAVTAMAFMEMLERGFTAVAEFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YLHNDSAGAPYADPAELATRVIEAAAQTGIGLTLLPVLYSAAGPNRPPEPGQRRFITDLD
HHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
GFLRLHAATAERLRALPGAVLGAAPHSLRAARAADVAALSGLLPEGPLHIHAAEQTGEVA
HHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHH
EVEAALGARPVEFLLREAGVDARWCLIHATHMAAEETAGLARAGAVAGLCPITEADLGDG
HHHHHHCCCHHHHHHHHCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IFNGNTFIDAGGRFGVGTDSNVAIEAPAELRQLEWSQRLRDRRRLVLADPARDGGSTGAA
EECCCEEEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHH
LYRAALAGGAQALAQPIGAIAPGCRADLVSLRRAGTDLAALSAETRLDHYIFAGGARLVD
HHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHEEECHHHHHH
RVYVAGRCLVREGRHDARAAIESRFAAALRRLEDAL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA