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The map label for this gene is mcpA [H]

Identifier: 148260693

GI number: 148260693

Start: 1876873

End: 1878648

Strand: Reverse

Name: mcpA [H]

Synonym: Acry_1697

Alternate gene names: 148260693

Gene position: 1878648-1876873 (Counterclockwise)

Preceding gene: 148260696

Following gene: 148260690

Centisome position: 55.43

GC content: 68.36

Gene sequence:

>1776_bases
ATGACGATTGGCAATATGCGTCAAATTTTAGATAATTCTCGAACATTCGACGCACTTGGGGACTCCTTCGGCATCATCAG
CTTTGCCCCCGACGGTACGATTACTGATGCCAACGACAATTTTCTTCAGTTGATGGGCTACCGCATCGGCGAAATCGCCG
GCCGCCATCACCGCATCTTTCTCTCCGCCGAGGAACGCGATGCCGCCGCCTACGGCGAGTTCTGGCAGCGCCTGCGCGGC
GGCGCCTTCTGCTCCGGCGAGTTCCGCCGCATCGCCAAGTCCGGCGGCGATGTCTGGCTCCGCGCCTCCTACGTCCCCGT
CCGCAACCGCGCCGGCAAGGTCGCGAAGGTGGTCAAGGTCGCCCTCGACATCACCGCCGAGAAACGGGCCGCCGCCGAAA
ACCAGAGCATCCTCAACGCCATCGAGCGCTCCCAGGCCGTCATCAAGTTCGCGCTCGACGGCACCATCCTCGAAGCCAAT
GACAATTTCCTCCACCTCATGGGCTACGCGCGCGACGAGGTCGTGGGCCGCCAGCACAGCCTCTTCGCGATCGATGGCTA
CGCCGCCAGCCGCGAATACCAGGCCTTCTGGGAGCGCCTGCGCCAGGGCGAATTCCTCTCCGCCGAGTTCGAGCGCGTCG
CCAAGGGCGGCCGCCACGTCTGGCTCCAGGCCACCTACAACCCGGTCTACGACGCCGAGGGCAAGGTCACGAAGGTCGTC
AAGTTCGCGGTCGACCTCACCGAACGCATGGCCGAGGTGAACGTCGTCGGCGACGCCCTCGAACGCGTCTCCGAAGGCGA
TCTCACCGCCTCCGTCGACCGCCAGCTGATCCCCTCGCTCGACAAGCTCCGCATCGACTTCAACACCGCCGCCAGCCGCC
TCGCCGAAAGCGTCAACGGCGTCCGCCAGAGCACCGACGAAATCAATCTCGGCGTCGCCGAAATCGCCGAAGCCGCCGAG
GATCTCGCCCGCCGCACCGAACAGCAGGCCTCCACCCTGGAGGAAACCTCCTCCGTGCTCGACAGCGTCACCACCGGCAT
CCGCCGCACCGCCGACAACGCCTCCAAGGCCGCCAGCGCCGTCGACGCCACCAACAACGCCGCGCGCAAGTCCCACGCCA
TCGTCGGCGAGGCCGTGGTCGCCATGAACCGCATCGAAACCTCCGCCCGCGAAATCGACCAGATCATCGGCCTGATCGAC
GAAATGGCCTTCCAGACCAACCTCCTCGCCCTCAACGCCGGGGTCGAGGCCGCCCGCGCCGGCGATGCCGGGCGCGGCTT
CGCCGTCGTCGCCTCCGAGGTCCGCGCCCTCGCGCACCGCTCCGCCGATGCCGCCAAATCCATCAAGCTGCTCATCGCCC
GCTCCTCCGAACAGGTCGGCAACGGCGTCCGCCTCGTCGGCGAAACCGGCACGGCACTGGATACCATCCTCGGCCACGTC
ACCGACCTGCACGGCCTCGTCGGCGAAATCGCCACCGCCGCCGCCGAACAGGCCGGCAGCCTCGCCGAAATCAACGCCGC
CACCGGCCAGATGAACCAGGCCGTCCAGCAGAACGCCGCCATGGTCGAACAGACCTCCGCCGCCACCCACTCCCTGCGCG
AGGAAATCAGCCGCCTCGCCGGCCGCGTCTCCGGCTTCCGCACCGCCCACGCCGCACCCGCCTACGCGGCACCCGCCCAC
GCGGCACCTGCCCACGCGGCACCGACAGCATCCGCCCCCATCGCCCCGGCCCGCACCCCGCCGCGCCGCGCGCGCCGCGT
CGCCGAACCCGCCTGA

Upstream 100 bases:

>100_bases
AGGCGGCGAAAAAACACGGACTGGCGCAAGAACCTGTTAAGAAAACCGGCATAGACCCGCAACAAACAAGAACAGACCAA
GTCAACACGGAGTCCGATAC

Downstream 100 bases:

>100_bases
CCCGACAGGCCCGATCCCGCCCGGCCGGGGCCGGGGGCAGGGCAGGGCGGGGGGAGCAAGGCGGAGCGGAGCAAAAACGC
TTGCCCATCCCCCGGCCTTC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 591; Mature: 590

Protein sequence:

>591_residues
MTIGNMRQILDNSRTFDALGDSFGIISFAPDGTITDANDNFLQLMGYRIGEIAGRHHRIFLSAEERDAAAYGEFWQRLRG
GAFCSGEFRRIAKSGGDVWLRASYVPVRNRAGKVAKVVKVALDITAEKRAAAENQSILNAIERSQAVIKFALDGTILEAN
DNFLHLMGYARDEVVGRQHSLFAIDGYAASREYQAFWERLRQGEFLSAEFERVAKGGRHVWLQATYNPVYDAEGKVTKVV
KFAVDLTERMAEVNVVGDALERVSEGDLTASVDRQLIPSLDKLRIDFNTAASRLAESVNGVRQSTDEINLGVAEIAEAAE
DLARRTEQQASTLEETSSVLDSVTTGIRRTADNASKAASAVDATNNAARKSHAIVGEAVVAMNRIETSAREIDQIIGLID
EMAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAHRSADAAKSIKLLIARSSEQVGNGVRLVGETGTALDTILGHV
TDLHGLVGEIATAAAEQAGSLAEINAATGQMNQAVQQNAAMVEQTSAATHSLREEISRLAGRVSGFRTAHAAPAYAAPAH
AAPAHAAPTASAPIAPARTPPRRARRVAEPA

Sequences:

>Translated_591_residues
MTIGNMRQILDNSRTFDALGDSFGIISFAPDGTITDANDNFLQLMGYRIGEIAGRHHRIFLSAEERDAAAYGEFWQRLRG
GAFCSGEFRRIAKSGGDVWLRASYVPVRNRAGKVAKVVKVALDITAEKRAAAENQSILNAIERSQAVIKFALDGTILEAN
DNFLHLMGYARDEVVGRQHSLFAIDGYAASREYQAFWERLRQGEFLSAEFERVAKGGRHVWLQATYNPVYDAEGKVTKVV
KFAVDLTERMAEVNVVGDALERVSEGDLTASVDRQLIPSLDKLRIDFNTAASRLAESVNGVRQSTDEINLGVAEIAEAAE
DLARRTEQQASTLEETSSVLDSVTTGIRRTADNASKAASAVDATNNAARKSHAIVGEAVVAMNRIETSAREIDQIIGLID
EMAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAHRSADAAKSIKLLIARSSEQVGNGVRLVGETGTALDTILGHV
TDLHGLVGEIATAAAEQAGSLAEINAATGQMNQAVQQNAAMVEQTSAATHSLREEISRLAGRVSGFRTAHAAPAYAAPAH
AAPAHAAPTASAPIAPARTPPRRARRVAEPA
>Mature_590_residues
TIGNMRQILDNSRTFDALGDSFGIISFAPDGTITDANDNFLQLMGYRIGEIAGRHHRIFLSAEERDAAAYGEFWQRLRGG
AFCSGEFRRIAKSGGDVWLRASYVPVRNRAGKVAKVVKVALDITAEKRAAAENQSILNAIERSQAVIKFALDGTILEAND
NFLHLMGYARDEVVGRQHSLFAIDGYAASREYQAFWERLRQGEFLSAEFERVAKGGRHVWLQATYNPVYDAEGKVTKVVK
FAVDLTERMAEVNVVGDALERVSEGDLTASVDRQLIPSLDKLRIDFNTAASRLAESVNGVRQSTDEINLGVAEIAEAAED
LARRTEQQASTLEETSSVLDSVTTGIRRTADNASKAASAVDATNNAARKSHAIVGEAVVAMNRIETSAREIDQIIGLIDE
MAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAHRSADAAKSIKLLIARSSEQVGNGVRLVGETGTALDTILGHVT
DLHGLVGEIATAAAEQAGSLAEINAATGQMNQAVQQNAAMVEQTSAATHSLREEISRLAGRVSGFRTAHAAPAYAAPAHA
APAHAAPTASAPIAPARTPPRRARRVAEPA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=301, Percent_Identity=41.8604651162791, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1788194, Length=292, Percent_Identity=38.3561643835616, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI1787690, Length=299, Percent_Identity=38.7959866220736, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI2367378, Length=298, Percent_Identity=39.9328859060403, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI1789453, Length=247, Percent_Identity=33.1983805668016, Blast_Score=135, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63159; Mature: 63028

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIGNMRQILDNSRTFDALGDSFGIISFAPDGTITDANDNFLQLMGYRIGEIAGRHHRIF
CCCCHHHHHHCCCCCHHHCCCCCCEEEECCCCCEECCCCHHHHHHHHHHHHHCCCCEEEE
LSAEERDAAAYGEFWQRLRGGAFCSGEFRRIAKSGGDVWLRASYVPVRNRAGKVAKVVKV
EECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEEECCHHCCCHHHHHHHHH
ALDITAEKRAAAENQSILNAIERSQAVIKFALDGTILEANDNFLHLMGYARDEVVGRQHS
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEECCCCEEEEECCHHHHHCCCCCC
LFAIDGYAASREYQAFWERLRQGEFLSAEFERVAKGGRHVWLQATYNPVYDAEGKVTKVV
EEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHH
KFAVDLTERMAEVNVVGDALERVSEGDLTASVDRQLIPSLDKLRIDFNTAASRLAESVNG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHH
VRQSTDEINLGVAEIAEAAEDLARRTEQQASTLEETSSVLDSVTTGIRRTADNASKAASA
HHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VDATNNAARKSHAIVGEAVVAMNRIETSAREIDQIIGLIDEMAFQTNLLALNAGVEAARA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHC
GDAGRGFAVVASEVRALAHRSADAAKSIKLLIARSSEQVGNGVRLVGETGTALDTILGHV
CCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHEECCHHHHCCCEEEEECCCHHHHHHHHHH
TDLHGLVGEIATAAAEQAGSLAEINAATGQMNQAVQQNAAMVEQTSAATHSLREEISRLA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRVSGFRTAHAAPAYAAPAHAAPAHAAPTASAPIAPARTPPRRARRVAEPA
HHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
TIGNMRQILDNSRTFDALGDSFGIISFAPDGTITDANDNFLQLMGYRIGEIAGRHHRIF
CCCHHHHHHCCCCCHHHCCCCCCEEEECCCCCEECCCCHHHHHHHHHHHHHCCCCEEEE
LSAEERDAAAYGEFWQRLRGGAFCSGEFRRIAKSGGDVWLRASYVPVRNRAGKVAKVVKV
EECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEEECCHHCCCHHHHHHHHH
ALDITAEKRAAAENQSILNAIERSQAVIKFALDGTILEANDNFLHLMGYARDEVVGRQHS
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEECCCCEEEEECCHHHHHCCCCCC
LFAIDGYAASREYQAFWERLRQGEFLSAEFERVAKGGRHVWLQATYNPVYDAEGKVTKVV
EEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHH
KFAVDLTERMAEVNVVGDALERVSEGDLTASVDRQLIPSLDKLRIDFNTAASRLAESVNG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHH
VRQSTDEINLGVAEIAEAAEDLARRTEQQASTLEETSSVLDSVTTGIRRTADNASKAASA
HHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VDATNNAARKSHAIVGEAVVAMNRIETSAREIDQIIGLIDEMAFQTNLLALNAGVEAARA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHC
GDAGRGFAVVASEVRALAHRSADAAKSIKLLIARSSEQVGNGVRLVGETGTALDTILGHV
CCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHEECCHHHHCCCEEEEECCCHHHHHHHHHH
TDLHGLVGEIATAAAEQAGSLAEINAATGQMNQAVQQNAAMVEQTSAATHSLREEISRLA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRVSGFRTAHAAPAYAAPAHAAPAHAAPTASAPIAPARTPPRRARRVAEPA
HHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]