BacMap

Definition	Acidiphilium cryptum JF-5 chromosome, complete genome.
Accession	NC_009484
Length	3,389,227

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The map label for this gene is fabG [H]

Identifier: 148260639

GI number: 148260639

Start: 1813365

End: 1814147

Strand: Reverse

Name: fabG [H]

Synonym: Acry_1641

Alternate gene names: 148260639

Gene position: 1814147-1813365 (Counterclockwise)

Preceding gene: 148260641

Following gene: 148260638

Centisome position: 53.53

GC content: 72.03

Gene sequence:

>783_bases
ATGGAACTCGGACTGAAGGGCAGGCGGGCGATCGTGTGCGCGGCGAGCAAGGGGCTCGGCCGCGCCGTCGCGTTTTCCCT
CGCCCGCGAGGGCGTGGATCTGGTGATCACCGCGCGCGGCGAGGCGGCGTTGGCCGAAACGGCGGCGGCGATCCGCGCCG
AGACCGGCGTCAAGGTCGAGATCGCGGCGGGCGACATCACCACCGAATCGGGCCGCGCCGCGGCGCTCGCCCTCTGCCCC
GCGCCGGACATCCTGATCAACAACGCGGGCGGCCCGCCGGCCGGCGATTTCCGCAAGTTCACCGATGCCGACTGGGAAGC
CGCCCTGCGCGCCAACATGCTCACCCCGATCGCGCTGATCCGTGCGACGGTCGATGGCATGATCGAGCGCCGCTTCGGCC
GCATCGTCAACATCACCTCGGCGGCGGTGAAATCGCCGATCCCCGCCCTCGGCCTGTCGAATGGCGCGCGCGCCGGGCTG
ACCGGCTTCGTCGCCGGCCTCGCCCGCCAGGTCGCGAAGCACAACGTGACGATCAACAATCTTCTCCCCGGCCCGTTCAT
GACCGACCGGCTGCGTGACAACGCGGCCACCGCCGCCCGCGCCTCCGGCCGCTCGGTGGAGGACGAACTCGCCGCCCGAG
CCGCCGCCAACCCGACCGGCCGCGTCGGCACGCCGGAGGAATTCGGCGATGCCTGCGCCTTCCTCTGCTCGGCACAGGCG
GGCTTCATCGTCGGCCAGAACCTGCTGCTCGATGGCGGCGCCTTCAACGCGGCGTTCGGCTGA

Upstream 100 bases:

>100_bases
GTCATGGCGGTGGTCATGGTCCCCTGTCGAATTCGGTATCGCGCCCATCTGATGCTATGGACGCGGCCTCGACACAAGCA
GGACAGGGAAGGGAGCAGAG

Downstream 100 bases:

>100_bases
CCTTGGCCTACCCGGTCTCGGATCATTTCGACGGCGCGCGCTTCTTCAACCCCGAAGGTGCGCGCCGCCGCACCGGCCGC
TTCCCGATGCTCCGCTGGGT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MELGLKGRRAIVCAASKGLGRAVAFSLAREGVDLVITARGEAALAETAAAIRAETGVKVEIAAGDITTESGRAAALALCP
APDILINNAGGPPAGDFRKFTDADWEAALRANMLTPIALIRATVDGMIERRFGRIVNITSAAVKSPIPALGLSNGARAGL
TGFVAGLARQVAKHNVTINNLLPGPFMTDRLRDNAATAARASGRSVEDELAARAAANPTGRVGTPEEFGDACAFLCSAQA
GFIVGQNLLLDGGAFNAAFG

Sequences:

>Translated_260_residues
MELGLKGRRAIVCAASKGLGRAVAFSLAREGVDLVITARGEAALAETAAAIRAETGVKVEIAAGDITTESGRAAALALCP
APDILINNAGGPPAGDFRKFTDADWEAALRANMLTPIALIRATVDGMIERRFGRIVNITSAAVKSPIPALGLSNGARAGL
TGFVAGLARQVAKHNVTINNLLPGPFMTDRLRDNAATAARASGRSVEDELAARAAANPTGRVGTPEEFGDACAFLCSAQA
GFIVGQNLLLDGGAFNAAFG
>Mature_260_residues
MELGLKGRRAIVCAASKGLGRAVAFSLAREGVDLVITARGEAALAETAAAIRAETGVKVEIAAGDITTESGRAAALALCP
APDILINNAGGPPAGDFRKFTDADWEAALRANMLTPIALIRATVDGMIERRFGRIVNITSAAVKSPIPALGLSNGARAGL
TGFVAGLARQVAKHNVTINNLLPGPFMTDRLRDNAATAARASGRSVEDELAARAAANPTGRVGTPEEFGDACAFLCSAQA
GFIVGQNLLLDGGAFNAAFG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=28.740157480315, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=26.4822134387352, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=25.5725190839695, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=28.9473684210526, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI226371731, Length=184, Percent_Identity=28.2608695652174, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=27.710843373494, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=25.4980079681275, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=26.7441860465116, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=26.7924528301887, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=31.6602316602317, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=28.2945736434109, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790717, Length=261, Percent_Identity=26.8199233716475, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=26.5060240963855, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=28.957528957529, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=26.953125, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=28.021978021978, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=28.740157480315, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=28.5171102661597, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=27.5193798449612, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=28.735632183908, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=28.8973384030418, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=28.3582089552239, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=26.6666666666667, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=26.9961977186312, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=26.4822134387352, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=27.1698113207547, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=27.4809160305344, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=273, Percent_Identity=27.4725274725275, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=27.5471698113208, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=26.9961977186312, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=28.8, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=269, Percent_Identity=28.996282527881, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=25.5725190839695, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=27.7992277992278, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=25.968992248062, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=26.615969581749, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=264, Percent_Identity=26.5151515151515, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=29.277566539924, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=25.7575757575758, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=25.8555133079848, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=28.735632183908, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=28.5171102661597, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=204, Percent_Identity=26.4705882352941, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=31.1284046692607, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=28.8461538461538, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI161076933, Length=215, Percent_Identity=29.3023255813954, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24584748, Length=215, Percent_Identity=29.3023255813954, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=29.6442687747036, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24584744, Length=217, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574402, Length=217, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=29.2490118577075, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=26.5625, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=25.0980392156863, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=23.3201581027668, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26522; Mature: 26522

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELGLKGRRAIVCAASKGLGRAVAFSLAREGVDLVITARGEAALAETAAAIRAETGVKVE
CCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCEEE
IAAGDITTESGRAAALALCPAPDILINNAGGPPAGDFRKFTDADWEAALRANMLTPIALI
EECCCEECCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RATVDGMIERRFGRIVNITSAAVKSPIPALGLSNGARAGLTGFVAGLARQVAKHNVTINN
HHHHHHHHHHHHHHEEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEECC
LLPGPFMTDRLRDNAATAARASGRSVEDELAARAAANPTGRVGTPEEFGDACAFLCSAQA
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
GFIVGQNLLLDGGAFNAAFG
CEEECCEEEEECCCCCCCCC
>Mature Secondary Structure
MELGLKGRRAIVCAASKGLGRAVAFSLAREGVDLVITARGEAALAETAAAIRAETGVKVE
CCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCEEE
IAAGDITTESGRAAALALCPAPDILINNAGGPPAGDFRKFTDADWEAALRANMLTPIALI
EECCCEECCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RATVDGMIERRFGRIVNITSAAVKSPIPALGLSNGARAGLTGFVAGLARQVAKHNVTINN
HHHHHHHHHHHHHHEEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEECC
LLPGPFMTDRLRDNAATAARASGRSVEDELAARAAANPTGRVGTPEEFGDACAFLCSAQA
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
GFIVGQNLLLDGGAFNAAFG
CEEECCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]