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The map label for this gene is gntR [H]

Identifier: 148260587

GI number: 148260587

Start: 1755654

End: 1756700

Strand: Reverse

Name: gntR [H]

Synonym: Acry_1589

Alternate gene names: 148260587

Gene position: 1756700-1755654 (Counterclockwise)

Preceding gene: 148260588

Following gene: 148260585

Centisome position: 51.83

GC content: 76.12

Gene sequence:

>1047_bases
ATGGCCTCCCCGCCCGACCGCGCGCCGACGATGGACGATGTGGCCGCCGCCGCCGGCGTGTCGAAGATGACGGTCTCGCG
GGCGCTGCGCGGCGCGCGCGTGGCGGCGGCGACGCGGGCGCGGATCATGGAGGCGGTGGCGCGGCTCGGCTATGTGCCGC
ACGCGGCGGCGGGCGCGCTGGCGAGCCGGCGGTCCGGCTTCGTCGCCGCCATCGTGCCCTCGATGGACAATTCGAATTTC
GCCGAGACGATCGCCGGGCTGGAGGCGGCGCTGCGCCAGGCGGGGCTCGACCTGCTGCTGGGGACCACGCTCTACAGCAA
TGCGCGCGAGGAGGAGCTGCTGCATACGCTGATGCGGCACCGGCCGGAGGGGATCGTGCTCACCGGCGGGGTGCACAGCC
GGCGGGTGGCCGCGTTGCTCGGCCGCTCGGCGCTGCCGGTGGTGGAGACCTGGGACCTGCCTTCATCCCCCATCGGCGGG
GTGGTCGGGTTTTCCAACCGCGCGGCGGGGGCTCTGATGACGGCGCATCTCGCCGCGATCGGGCGGCGGCGGATCGCCTT
TCTCGGCGGCGCCTCAAGGCGGGACCCGCGCGGCGAGGATCGCGGCCGGGGGTATGAGGAGGCGCTGGCGGCCGCCGGGC
TCGGGCCGCCGCTGCTGTTCCGCCACGGCCAGCCGCCGCTGTCGATGCGGCACGGGGCGGAGGGCATGGCGCTGCTGCTG
GAACGCTGGCCGGAGACCGACGCGGTGGTGTGCGCCAGCGACCTGATCGCCTTCGGCGCGATCGCCGAATGCCAGCGGCG
GGGGATCGGCGTGCCGGAGCGGATCGCCATCGGCGGGTTCGGGGATTTCGAGGTGTCGCGCTGCGCGGTGCCGGCGATCA
GCACGGTGGCGGTGGATGCGCGGGGCATCGGCGAGCGGGCCGGGGCGATGCTGGTGCGCGCGGTGGCGGCCCGCCGCCGC
GGCGAGGCGGCAGCGCCGGAGCGGATCGAGGTCGGACTCCGGCTGGCGGCGCGGGGCAGCACCGTCGCGCCGCGCCGGGA
TTCATGA

Upstream 100 bases:

>100_bases
GCGCGGTGCTGCCGGCGGAGCGGGCGGCGGAGGCCTTCGCGCTCGCGGCGGACAAGGCGCGGGCGGTGAAGGTCCAGCTC
GCCTTCTAGGCGGTTCCGCG

Downstream 100 bases:

>100_bases
CGCCGCGAGTTCGAGACGGCGGGCGGCGGCTTGCGGCGATTGCTGCGAGAAGCGGAAATGGGAGACGATGTTGGCCAGCG
CCGTCGCCTCGCCGGCGAGG

Product: alanine racemase

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MASPPDRAPTMDDVAAAAGVSKMTVSRALRGARVAAATRARIMEAVARLGYVPHAAAGALASRRSGFVAAIVPSMDNSNF
AETIAGLEAALRQAGLDLLLGTTLYSNAREEELLHTLMRHRPEGIVLTGGVHSRRVAALLGRSALPVVETWDLPSSPIGG
VVGFSNRAAGALMTAHLAAIGRRRIAFLGGASRRDPRGEDRGRGYEEALAAAGLGPPLLFRHGQPPLSMRHGAEGMALLL
ERWPETDAVVCASDLIAFGAIAECQRRGIGVPERIAIGGFGDFEVSRCAVPAISTVAVDARGIGERAGAMLVRAVAARRR
GEAAAPERIEVGLRLAARGSTVAPRRDS

Sequences:

>Translated_348_residues
MASPPDRAPTMDDVAAAAGVSKMTVSRALRGARVAAATRARIMEAVARLGYVPHAAAGALASRRSGFVAAIVPSMDNSNF
AETIAGLEAALRQAGLDLLLGTTLYSNAREEELLHTLMRHRPEGIVLTGGVHSRRVAALLGRSALPVVETWDLPSSPIGG
VVGFSNRAAGALMTAHLAAIGRRRIAFLGGASRRDPRGEDRGRGYEEALAAAGLGPPLLFRHGQPPLSMRHGAEGMALLL
ERWPETDAVVCASDLIAFGAIAECQRRGIGVPERIAIGGFGDFEVSRCAVPAISTVAVDARGIGERAGAMLVRAVAARRR
GEAAAPERIEVGLRLAARGSTVAPRRDS
>Mature_347_residues
ASPPDRAPTMDDVAAAAGVSKMTVSRALRGARVAAATRARIMEAVARLGYVPHAAAGALASRRSGFVAAIVPSMDNSNFA
ETIAGLEAALRQAGLDLLLGTTLYSNAREEELLHTLMRHRPEGIVLTGGVHSRRVAALLGRSALPVVETWDLPSSPIGGV
VGFSNRAAGALMTAHLAAIGRRRIAFLGGASRRDPRGEDRGRGYEEALAAAGLGPPLLFRHGQPPLSMRHGAEGMALLLE
RWPETDAVVCASDLIAFGAIAECQRRGIGVPERIAIGGFGDFEVSRCAVPAISTVAVDARGIGERAGAMLVRAVAARRRG
EAAAPERIEVGLRLAARGSTVAPRRDS

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=335, Percent_Identity=33.7313432835821, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1790715, Length=309, Percent_Identity=33.3333333333333, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1790369, Length=343, Percent_Identity=27.9883381924198, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789202, Length=294, Percent_Identity=31.2925170068027, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789068, Length=353, Percent_Identity=28.8951841359773, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787948, Length=342, Percent_Identity=26.9005847953216, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1790194, Length=335, Percent_Identity=26.865671641791, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788474, Length=292, Percent_Identity=27.7397260273973, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787906, Length=266, Percent_Identity=34.5864661654135, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786540, Length=350, Percent_Identity=26, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790689, Length=329, Percent_Identity=25.8358662613982, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787580, Length=351, Percent_Identity=23.9316239316239, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36287; Mature: 36156

Theoretical pI: Translated: 11.28; Mature: 11.28

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPPDRAPTMDDVAAAAGVSKMTVSRALRGARVAAATRARIMEAVARLGYVPHAAAGAL
CCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ASRRSGFVAAIVPSMDNSNFAETIAGLEAALRQAGLDLLLGTTLYSNAREEELLHTLMRH
HHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHH
RPEGIVLTGGVHSRRVAALLGRSALPVVETWDLPSSPIGGVVGFSNRAAGALMTAHLAAI
CCCCEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCEECCCCCHHHHHHHHHHHHH
GRRRIAFLGGASRRDPRGEDRGRGYEEALAAAGLGPPLLFRHGQPPLSMRHGAEGMALLL
HHHHEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHCCCCCCCCHHHCCCHHHHHHH
ERWPETDAVVCASDLIAFGAIAECQRRGIGVPERIAIGGFGDFEVSRCAVPAISTVAVDA
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHCCCHHHHEEECC
RGIGERAGAMLVRAVAARRRGEAAAPERIEVGLRLAARGSTVAPRRDS
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
ASPPDRAPTMDDVAAAAGVSKMTVSRALRGARVAAATRARIMEAVARLGYVPHAAAGAL
CCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ASRRSGFVAAIVPSMDNSNFAETIAGLEAALRQAGLDLLLGTTLYSNAREEELLHTLMRH
HHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHH
RPEGIVLTGGVHSRRVAALLGRSALPVVETWDLPSSPIGGVVGFSNRAAGALMTAHLAAI
CCCCEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCEECCCCCHHHHHHHHHHHHH
GRRRIAFLGGASRRDPRGEDRGRGYEEALAAAGLGPPLLFRHGQPPLSMRHGAEGMALLL
HHHHEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHCCCCCCCCHHHCCCHHHHHHH
ERWPETDAVVCASDLIAFGAIAECQRRGIGVPERIAIGGFGDFEVSRCAVPAISTVAVDA
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHCCCHHHHEEECC
RGIGERAGAMLVRAVAARRRGEAAAPERIEVGLRLAARGSTVAPRRDS
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]