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The map label for this gene is aroB [H]

Identifier: 148260467

GI number: 148260467

Start: 1629352

End: 1631010

Strand: Reverse

Name: aroB [H]

Synonym: Acry_1467

Alternate gene names: 148260467

Gene position: 1631010-1629352 (Counterclockwise)

Preceding gene: 148260469

Following gene: 148260466

Centisome position: 48.12

GC content: 66.73

Gene sequence:

>1659_bases
ATGTTCGACAAGAGTTTTCATTCACCCGGCCTTCCTGTCGCCTTGCCGATGCGCAGCATCGTGCTGATCGGACTGATGGG
GGCTGGCAAGTCGGCGGTCGGCCGCCGGCTCGCGGCCCAACTGGCCCTGCCGTTTCACGATTCCGATGCCGAGATTGAGG
CGGCCGCGGGCAAGACGGTTGCGGATATTTTCGCTTCAGAAGGCGAAGCCGCCTTCCGGGCGCGCGAAAGGGCCATGATT
GCCGAGCTTTTGGCCGGTCCGCCGATCGTTCTGGCGACCGGCGGCGGCGCCTTCATGGACCCCGAGACCCGCGCAGTGAT
TGGCGCGCGGGCCATTTCCGTCTGGCTGCGGGCGACGCTCGACGTGCTTCTGGCCCGGGTGCGCGGCCGCACCCATCGGC
CACTGCTTAATCAGGGCGACCCTGCCGAAATCCTGTCCCGGCTTTCCGCGCTGCGTGCGCCGGTCTATGCCGAAGCGGAC
ATCATCGTTGACAGTACCGAGGCCCCGCCTGACATGACCACCGAGACCGTTGCCGCTGCCATCGCTCGCCACGCGCCCGA
GCGGACCATTCGGATCGAGCTTCCCGATGCCGGCTATGACGTGGTGATCGGCCGCGGATTGCTCGATGGCGCGGGTGCCC
GTCTCGCCGCAGCCCTGCCGTCGCGTCGCGCCGTGGTGGTGACCGACGCGAACGTGGCGCAGACACATCTGCCGCGACTC
GAACGCGCGCTTGACGATGCGGGCTTCATCCACGACCGGATCGTGGTTCCGCCGGGCGAAGGATCAAAAAGCCTCTCCCG
TTTTGCCGCACTGGTTGAGGACATTCTTGCCCTGAAGCCGGAGCGGCAGACCGCGATCATCGCGCTTGGCGGCGGCGTCA
TCGGCGATCTGGCCGGGTTCGCTGCTTCCAGCGTGCTGCGCGGGCTGCCCTTCGCGCAGGTTCCGACCTCGCTGCTCGCG
CAGGTTGATTCCAGCGTCGGTGGCAAGACCGGCGTCAATTCGCGCCACGGCAAGAACCTGATCGGCGCGTTTCATCAGCC
GCGTCTTGTCGTCATCGACAGCGATACGTTGGCCACCCTGTCGCGGCGCCAGGCCGCCGCAGGCTATGCTGAAATCGTCA
AGGCGGGGCTCATCGCCGATCCCGCGCTCTATGAATGGTGCGAAGCCCATGGCGCCGCGCTGCTTGGTGGCGACCAGGGC
TTGCAGGAAGAGGCGATTGCCCGCGCTGTTGCCTTCAAGGCGCAGGTGGTGATGGCCGATCCGCGCGAGCAGGCCAAGCG
GGATGGCCGCGCGCTGCTCAATCTCGGCCACACTTTCGCTCACGCCTTCGAGGCCGAGACCGGTTATGGCGAGGCGCTGC
TGCACGGCGAGGCGGTGGCGATCGGCATGGTTTGCGCTTTCGACCTCTCGGCCCGTCTTGGTTATTGCGATGCGGGAATC
GTTCCGCGCATTGCCGCGCATCTGGACGAGGTCGGCCTTCCGCACCGGATCGGCGGCTGGAACGCGGAAGCGCTGCTCGG
CCACATGCAGAGCGATAAGAAGATGCGGGACGGCAGGCTAGCCTTCGTTTTGGCCCGTGGGATCGGCAGTGCGTTCACTA
GCCGCGAGGTGCCGCAGGAAGCTGTTCGGGCAACGCTTGCGGCCTGTGGCGCGGGCTGA

Upstream 100 bases:

>100_bases
TAGTATTCCGCGCCGCGCCGCGCTCTGCGACCATTGATTCAAGGAAGGCCTCGATATGCCGCTCTAGTGCCATCGTGTTT
TTGTGGTAAGCCGCAGCACA

Downstream 100 bases:

>100_bases
CCGACGCCAATGTATACTCCGCCGGCTTTCGCCGAGGATGATCCCGCAATCATCGCGGCGATCATGCGCGCCTGCCGCTT
GCCCGTTCTCGTCAGTGCCG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MFDKSFHSPGLPVALPMRSIVLIGLMGAGKSAVGRRLAAQLALPFHDSDAEIEAAAGKTVADIFASEGEAAFRARERAMI
AELLAGPPIVLATGGGAFMDPETRAVIGARAISVWLRATLDVLLARVRGRTHRPLLNQGDPAEILSRLSALRAPVYAEAD
IIVDSTEAPPDMTTETVAAAIARHAPERTIRIELPDAGYDVVIGRGLLDGAGARLAAALPSRRAVVVTDANVAQTHLPRL
ERALDDAGFIHDRIVVPPGEGSKSLSRFAALVEDILALKPERQTAIIALGGGVIGDLAGFAASSVLRGLPFAQVPTSLLA
QVDSSVGGKTGVNSRHGKNLIGAFHQPRLVVIDSDTLATLSRRQAAAGYAEIVKAGLIADPALYEWCEAHGAALLGGDQG
LQEEAIARAVAFKAQVVMADPREQAKRDGRALLNLGHTFAHAFEAETGYGEALLHGEAVAIGMVCAFDLSARLGYCDAGI
VPRIAAHLDEVGLPHRIGGWNAEALLGHMQSDKKMRDGRLAFVLARGIGSAFTSREVPQEAVRATLAACGAG

Sequences:

>Translated_552_residues
MFDKSFHSPGLPVALPMRSIVLIGLMGAGKSAVGRRLAAQLALPFHDSDAEIEAAAGKTVADIFASEGEAAFRARERAMI
AELLAGPPIVLATGGGAFMDPETRAVIGARAISVWLRATLDVLLARVRGRTHRPLLNQGDPAEILSRLSALRAPVYAEAD
IIVDSTEAPPDMTTETVAAAIARHAPERTIRIELPDAGYDVVIGRGLLDGAGARLAAALPSRRAVVVTDANVAQTHLPRL
ERALDDAGFIHDRIVVPPGEGSKSLSRFAALVEDILALKPERQTAIIALGGGVIGDLAGFAASSVLRGLPFAQVPTSLLA
QVDSSVGGKTGVNSRHGKNLIGAFHQPRLVVIDSDTLATLSRRQAAAGYAEIVKAGLIADPALYEWCEAHGAALLGGDQG
LQEEAIARAVAFKAQVVMADPREQAKRDGRALLNLGHTFAHAFEAETGYGEALLHGEAVAIGMVCAFDLSARLGYCDAGI
VPRIAAHLDEVGLPHRIGGWNAEALLGHMQSDKKMRDGRLAFVLARGIGSAFTSREVPQEAVRATLAACGAG
>Mature_552_residues
MFDKSFHSPGLPVALPMRSIVLIGLMGAGKSAVGRRLAAQLALPFHDSDAEIEAAAGKTVADIFASEGEAAFRARERAMI
AELLAGPPIVLATGGGAFMDPETRAVIGARAISVWLRATLDVLLARVRGRTHRPLLNQGDPAEILSRLSALRAPVYAEAD
IIVDSTEAPPDMTTETVAAAIARHAPERTIRIELPDAGYDVVIGRGLLDGAGARLAAALPSRRAVVVTDANVAQTHLPRL
ERALDDAGFIHDRIVVPPGEGSKSLSRFAALVEDILALKPERQTAIIALGGGVIGDLAGFAASSVLRGLPFAQVPTSLLA
QVDSSVGGKTGVNSRHGKNLIGAFHQPRLVVIDSDTLATLSRRQAAAGYAEIVKAGLIADPALYEWCEAHGAALLGGDQG
LQEEAIARAVAFKAQVVMADPREQAKRDGRALLNLGHTFAHAFEAETGYGEALLHGEAVAIGMVCAFDLSARLGYCDAGI
VPRIAAHLDEVGLPHRIGGWNAEALLGHMQSDKKMRDGRLAFVLARGIGSAFTSREVPQEAVRATLAACGAG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=366, Percent_Identity=43.7158469945355, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI87082255, Length=165, Percent_Identity=44.8484848484849, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1786587, Length=164, Percent_Identity=34.7560975609756, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320332, Length=408, Percent_Identity=31.8627450980392, Blast_Score=174, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 57732; Mature: 57732

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDKSFHSPGLPVALPMRSIVLIGLMGAGKSAVGRRLAAQLALPFHDSDAEIEAAAGKTV
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEHHCCCHH
ADIFASEGEAAFRARERAMIAELLAGPPIVLATGGGAFMDPETRAVIGARAISVWLRATL
HHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
DVLLARVRGRTHRPLLNQGDPAEILSRLSALRAPVYAEADIIVDSTEAPPDMTTETVAAA
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEECCEEEEECCCCCCCCHHHHHHHH
IARHAPERTIRIELPDAGYDVVIGRGLLDGAGARLAAALPSRRAVVVTDANVAQTHLPRL
HHHCCCCCEEEEECCCCCCEEEEECCCCCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHH
ERALDDAGFIHDRIVVPPGEGSKSLSRFAALVEDILALKPERQTAIIALGGGVIGDLAGF
HHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHH
AASSVLRGLPFAQVPTSLLAQVDSSVGGKTGVNSRHGKNLIGAFHQPRLVVIDSDTLATL
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCHHHHH
SRRQAAAGYAEIVKAGLIADPALYEWCEAHGAALLGGDQGLQEEAIARAVAFKAQVVMAD
HHHHHHCCHHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHEEEEEEC
PREQAKRDGRALLNLGHTFAHAFEAETGYGEALLHGEAVAIGMVCAFDLSARLGYCDAGI
CHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHCCCCCCCCCH
VPRIAAHLDEVGLPHRIGGWNAEALLGHMQSDKKMRDGRLAFVLARGIGSAFTSREVPQE
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHCCCCEEEEEEHHHCHHHHHCCCCHH
AVRATLAACGAG
HHHHHHHHHCCC
>Mature Secondary Structure
MFDKSFHSPGLPVALPMRSIVLIGLMGAGKSAVGRRLAAQLALPFHDSDAEIEAAAGKTV
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEHHCCCHH
ADIFASEGEAAFRARERAMIAELLAGPPIVLATGGGAFMDPETRAVIGARAISVWLRATL
HHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
DVLLARVRGRTHRPLLNQGDPAEILSRLSALRAPVYAEADIIVDSTEAPPDMTTETVAAA
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEECCEEEEECCCCCCCCHHHHHHHH
IARHAPERTIRIELPDAGYDVVIGRGLLDGAGARLAAALPSRRAVVVTDANVAQTHLPRL
HHHCCCCCEEEEECCCCCCEEEEECCCCCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHH
ERALDDAGFIHDRIVVPPGEGSKSLSRFAALVEDILALKPERQTAIIALGGGVIGDLAGF
HHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHH
AASSVLRGLPFAQVPTSLLAQVDSSVGGKTGVNSRHGKNLIGAFHQPRLVVIDSDTLATL
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCHHHHH
SRRQAAAGYAEIVKAGLIADPALYEWCEAHGAALLGGDQGLQEEAIARAVAFKAQVVMAD
HHHHHHCCHHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHEEEEEEC
PREQAKRDGRALLNLGHTFAHAFEAETGYGEALLHGEAVAIGMVCAFDLSARLGYCDAGI
CHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHCCCCCCCCCH
VPRIAAHLDEVGLPHRIGGWNAEALLGHMQSDKKMRDGRLAFVLARGIGSAFTSREVPQE
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHCCCCEEEEEEHHHCHHHHHCCCCHH
AVRATLAACGAG
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA