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The map label for this gene is mcpA [H]

Identifier: 148260291

GI number: 148260291

Start: 1437294

End: 1439069

Strand: Reverse

Name: mcpA [H]

Synonym: Acry_1288

Alternate gene names: 148260291

Gene position: 1439069-1437294 (Counterclockwise)

Preceding gene: 148260297

Following gene: 148260286

Centisome position: 42.46

GC content: 67.91

Gene sequence:

>1776_bases
GTGGTTATTGGGAAGCTACGTCAAATCTCTGACAAAAGCAGGATGTTTGATGCCATTGGAAACTCCTTCGGCATCATCGG
TTTCAAACCCGACGGCACGATCATCGACGCCAACGACAGTTTTCTCCGTTTGATGGGCTACGGCGCCGCCGACATCATCG
GGCGCCATCATCGTATTTTTGTAACCGTAACCGAGCGCGACAGCGCCGCCTACGGCGAGTTCTGGCAGCGCCTGCGCGGC
GGCGCCTTCTGCTCCGGCGAGTTCCGCCGCATCGCCAAGTCCGGCCACGATGTCTGGCTCCGCGCCTCCTACGTCCCCGT
CCGCAACCGCGCCGGCAAGGTCGCGAAGGTGGTCAAGGTCGCCCTCGACATCACCGCCGAGAAACGGGCCGCCGCCGAAA
ACGAAAGCATCCTCAACGCCATCGAGCGCTCCCAGGCCGTCATCAAGTTCGCGCTCGACGGCACCATCCTCGAAGCCAAC
GACAACTTCCTTCGCGTGATGGGTTACGCGCGCGACGAGATCGTGGGCCGCAAGCACAGCATGTTCGCTACACCAGCATA
CGCCGCCAGCCGCGAATACCAGGCCTTCTGGGAGCGCCTGCGCCAGGGCGAATTCATCGCTGGTGATTTCGAGCGCGTGG
GCAAGGGCGGCCGCCACGTCTGGCTCCAGGCCACCTACAACCCGGTCTACGACGCCGAGGGCAAGGTGACGAAGGTCGTC
AAGTTCGCGGTCGACCTCACCGAACGCATGGCCGAGGTCGGCCTCGTCGGCGACGCCCTCGAACGCGTCTCCGAAGGTGA
TCTCACCGCCTCCGTCGACCGCCAGCTGATCCCCTCGCTCGACAAGCTCCGCATCGACTTCAACACCGCCGCCAGCCGCC
TCGCCGAAAGCGTCAACGGCGTCCGCCAGAGCACCGACGAAATCAATCTCGGCGTCGCCGAAATCGCCGAAGCCGCCGAG
GATCTCGCCCGCCGCACCGAACAGCAGGCCTCCACCCTGGAGGAAACCTCATCCGTGCTCGACAGCGTCACCACCGGCAT
CCGCCGCACCGCCGACAACGCCTCCAAGGCCGCCAGCGCCGTCGACGCCACCAACAACGCCGCCCGCAAGTCCCACGCCA
TCGTCGGCGAGGCCGTGGTCGCCATGAACCGCATCGAAACATCCGCCCGCGAAATCGACCAGATCATCGGCCTGATCGAT
GAAATGGCCTTCCAGACCAACCTCCTCGCCCTCAACGCCGGGGTCGAGGCCGCCCGCGCCGGCGATGCCGGGCGCGGCTT
CGCCGTCGTCGCCTCCGAGGTCCGCGCCCTCGCGCACCGCTCCGCCGATGCCGCCAAATCCATCAAGCTGCTCATCGCCC
GCTCCTCCGAACAGGTCGGCAACGGCGTCCGCCTCGTCGGCGAAACCGGCACCGCGCTCGATACCATCCTCGGCCACGTC
ACCGACCTGCACGGCCTCGTCGGCGAAATCGCCACCGCCGCCGCCGAACAGGCCGGCAGCCTCGCCGAAATCAACGCCGC
CACCGGCCAGATGAACCAGGCCGTCCAGCAGAACGCCGCCATGGTCGAGCAGACCTCCGCCGCCACCCACTCCCTGCGCG
AGGAAATCAGCCGCCTCGCCGGCCGCGTCTCCGGCTTCCGCACCGCCCACGCCGCACCCGCCTACGCGGCACCCGCCCAC
GCGGCACCTGCCCACGCGGCACCGACAGCATCCGCCCCCATCGCCCCGGCCCGCACCCCGCCGCGCCGCGCGCGCCGCGT
CGCCGAACCCGCCTGA

Upstream 100 bases:

>100_bases
AGCATGAAAATATCAGATTCCGGTAATACATTGTTAAGGAGACCCGGATAGAAGTTTTATTTAATAAAATAGATCAATCA
ATAAAAATGGGAATTGTTTC

Downstream 100 bases:

>100_bases
CCCGACAGGCCCGATCCCGCCCGGCCGGGGCCGGGCGGGGCCCCCCACTGGATGAGAGAAATTGCTCTTTACTTTAGTGA
CTTACAGTAAGCCGCGCGGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MVIGKLRQISDKSRMFDAIGNSFGIIGFKPDGTIIDANDSFLRLMGYGAADIIGRHHRIFVTVTERDSAAYGEFWQRLRG
GAFCSGEFRRIAKSGHDVWLRASYVPVRNRAGKVAKVVKVALDITAEKRAAAENESILNAIERSQAVIKFALDGTILEAN
DNFLRVMGYARDEIVGRKHSMFATPAYAASREYQAFWERLRQGEFIAGDFERVGKGGRHVWLQATYNPVYDAEGKVTKVV
KFAVDLTERMAEVGLVGDALERVSEGDLTASVDRQLIPSLDKLRIDFNTAASRLAESVNGVRQSTDEINLGVAEIAEAAE
DLARRTEQQASTLEETSSVLDSVTTGIRRTADNASKAASAVDATNNAARKSHAIVGEAVVAMNRIETSAREIDQIIGLID
EMAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAHRSADAAKSIKLLIARSSEQVGNGVRLVGETGTALDTILGHV
TDLHGLVGEIATAAAEQAGSLAEINAATGQMNQAVQQNAAMVEQTSAATHSLREEISRLAGRVSGFRTAHAAPAYAAPAH
AAPAHAAPTASAPIAPARTPPRRARRVAEPA

Sequences:

>Translated_591_residues
MVIGKLRQISDKSRMFDAIGNSFGIIGFKPDGTIIDANDSFLRLMGYGAADIIGRHHRIFVTVTERDSAAYGEFWQRLRG
GAFCSGEFRRIAKSGHDVWLRASYVPVRNRAGKVAKVVKVALDITAEKRAAAENESILNAIERSQAVIKFALDGTILEAN
DNFLRVMGYARDEIVGRKHSMFATPAYAASREYQAFWERLRQGEFIAGDFERVGKGGRHVWLQATYNPVYDAEGKVTKVV
KFAVDLTERMAEVGLVGDALERVSEGDLTASVDRQLIPSLDKLRIDFNTAASRLAESVNGVRQSTDEINLGVAEIAEAAE
DLARRTEQQASTLEETSSVLDSVTTGIRRTADNASKAASAVDATNNAARKSHAIVGEAVVAMNRIETSAREIDQIIGLID
EMAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAHRSADAAKSIKLLIARSSEQVGNGVRLVGETGTALDTILGHV
TDLHGLVGEIATAAAEQAGSLAEINAATGQMNQAVQQNAAMVEQTSAATHSLREEISRLAGRVSGFRTAHAAPAYAAPAH
AAPAHAAPTASAPIAPARTPPRRARRVAEPA
>Mature_591_residues
MVIGKLRQISDKSRMFDAIGNSFGIIGFKPDGTIIDANDSFLRLMGYGAADIIGRHHRIFVTVTERDSAAYGEFWQRLRG
GAFCSGEFRRIAKSGHDVWLRASYVPVRNRAGKVAKVVKVALDITAEKRAAAENESILNAIERSQAVIKFALDGTILEAN
DNFLRVMGYARDEIVGRKHSMFATPAYAASREYQAFWERLRQGEFIAGDFERVGKGGRHVWLQATYNPVYDAEGKVTKVV
KFAVDLTERMAEVGLVGDALERVSEGDLTASVDRQLIPSLDKLRIDFNTAASRLAESVNGVRQSTDEINLGVAEIAEAAE
DLARRTEQQASTLEETSSVLDSVTTGIRRTADNASKAASAVDATNNAARKSHAIVGEAVVAMNRIETSAREIDQIIGLID
EMAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAHRSADAAKSIKLLIARSSEQVGNGVRLVGETGTALDTILGHV
TDLHGLVGEIATAAAEQAGSLAEINAATGQMNQAVQQNAAMVEQTSAATHSLREEISRLAGRVSGFRTAHAAPAYAAPAH
AAPAHAAPTASAPIAPARTPPRRARRVAEPA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=301, Percent_Identity=41.8604651162791, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1788194, Length=294, Percent_Identity=38.0952380952381, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1787690, Length=299, Percent_Identity=38.7959866220736, Blast_Score=181, Evalue=9e-47,
Organism=Escherichia coli, GI2367378, Length=290, Percent_Identity=40.3448275862069, Blast_Score=168, Evalue=8e-43,
Organism=Escherichia coli, GI1789453, Length=247, Percent_Identity=33.1983805668016, Blast_Score=135, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63129; Mature: 63129

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIGKLRQISDKSRMFDAIGNSFGIIGFKPDGTIIDANDSFLRLMGYGAADIIGRHHRIF
CCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCCCHHHHCCCHHHHCCCCEEEE
VTVTERDSAAYGEFWQRLRGGAFCSGEFRRIAKSGHDVWLRASYVPVRNRAGKVAKVVKV
EEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEEECCHHCCCHHHHHHHHH
ALDITAEKRAAAENESILNAIERSQAVIKFALDGTILEANDNFLRVMGYARDEIVGRKHS
HHHHHHHHHHHHCHHHHHHHHHHHHHHEEEEECCEEEECCCCEEEEHHHHHHHHHCCCCC
MFATPAYAASREYQAFWERLRQGEFIAGDFERVGKGGRHVWLQATYNPVYDAEGKVTKVV
CCCCCHHHHCHHHHHHHHHHHCCCCEECCHHHHCCCCCEEEEEEECCCCCCCCCCHHHHH
KFAVDLTERMAEVGLVGDALERVSEGDLTASVDRQLIPSLDKLRIDFNTAASRLAESVNG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHH
VRQSTDEINLGVAEIAEAAEDLARRTEQQASTLEETSSVLDSVTTGIRRTADNASKAASA
HHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VDATNNAARKSHAIVGEAVVAMNRIETSAREIDQIIGLIDEMAFQTNLLALNAGVEAARA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHC
GDAGRGFAVVASEVRALAHRSADAAKSIKLLIARSSEQVGNGVRLVGETGTALDTILGHV
CCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHEECCCHHHCCCEEEEECCCHHHHHHHHHH
TDLHGLVGEIATAAAEQAGSLAEINAATGQMNQAVQQNAAMVEQTSAATHSLREEISRLA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRVSGFRTAHAAPAYAAPAHAAPAHAAPTASAPIAPARTPPRRARRVAEPA
HHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure
MVIGKLRQISDKSRMFDAIGNSFGIIGFKPDGTIIDANDSFLRLMGYGAADIIGRHHRIF
CCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCCCHHHHCCCHHHHCCCCEEEE
VTVTERDSAAYGEFWQRLRGGAFCSGEFRRIAKSGHDVWLRASYVPVRNRAGKVAKVVKV
EEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEEECCHHCCCHHHHHHHHH
ALDITAEKRAAAENESILNAIERSQAVIKFALDGTILEANDNFLRVMGYARDEIVGRKHS
HHHHHHHHHHHHCHHHHHHHHHHHHHHEEEEECCEEEECCCCEEEEHHHHHHHHHCCCCC
MFATPAYAASREYQAFWERLRQGEFIAGDFERVGKGGRHVWLQATYNPVYDAEGKVTKVV
CCCCCHHHHCHHHHHHHHHHHCCCCEECCHHHHCCCCCEEEEEEECCCCCCCCCCHHHHH
KFAVDLTERMAEVGLVGDALERVSEGDLTASVDRQLIPSLDKLRIDFNTAASRLAESVNG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHH
VRQSTDEINLGVAEIAEAAEDLARRTEQQASTLEETSSVLDSVTTGIRRTADNASKAASA
HHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VDATNNAARKSHAIVGEAVVAMNRIETSAREIDQIIGLIDEMAFQTNLLALNAGVEAARA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHC
GDAGRGFAVVASEVRALAHRSADAAKSIKLLIARSSEQVGNGVRLVGETGTALDTILGHV
CCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHEECCCHHHCCCEEEEECCCHHHHHHHHHH
TDLHGLVGEIATAAAEQAGSLAEINAATGQMNQAVQQNAAMVEQTSAATHSLREEISRLA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRVSGFRTAHAAPAYAAPAHAAPAHAAPTASAPIAPARTPPRRARRVAEPA
HHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]