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The map label for this gene is yitU [H]

Identifier: 148260277

GI number: 148260277

Start: 1421896

End: 1422714

Strand: Reverse

Name: yitU [H]

Synonym: Acry_1274

Alternate gene names: 148260277

Gene position: 1422714-1421896 (Counterclockwise)

Preceding gene: 148260278

Following gene: 148260276

Centisome position: 41.98

GC content: 64.47

Gene sequence:

>819_bases
ATGAGCCGCGCGGTCGATCTCGTGATTGCCGATGTCGATGGCACCCTGGTCACCAATGACAAGCGCCTGACGGCGGCGAC
GAAGCTGGCGGTCGATGCGCTTCGCGAGGCGGGCATCCGCTTCGCGATCACCAGCGGGCGGCCGCCGCGCGGCATGCGGA
TGCTGAGCGAACCGCTCGCCATCGACACGCCGCTGGCCGGGTTCAACGGCGGCGTGATGATGGCCCCCGATTTCAGCCGC
GTCGTCGCCTCGCACGACCTGCAGGACGACGTGATCGGCAAGGCCATCGATCTGCTCGATGACCATGGCCTCGATGCCTG
GGTCTACACGCATGATCGCTGGCTGGTCCGCGATGCCGCGGCGCCGCATGTCGATCGCGAACAGCGTACCGTCGCGTTCG
AGCCGGAGACCGTCGAGCGCTACGATGTATCGTCTCTTCATGGCGTCGTGAAGATCGTCGGGGTGACCGATGACGCCGAG
CGTATGAAATCCTGCCTTGCCGCCGCGCACAAGGCGTTCGGTGACGGCGTGACGGCGGACTGCTCGCAGCCCTATTATCT
CGATATCACCAGCGCACATGCGAACAAGGGCGCGGTGGTGGATGCGATGTCGAGCGAGCTCGGCATCCCGCACGAGCGTA
TCGCGACCATCGGCGACATGCCGAACGATGTTGCCATGTTTGCCCGTAGCGGCCTTTCCATCGCGATGGGCAATGCCGAT
GACAGTGTCAAGCGGAAGGCGGATCATGCCACACGCGGCAATGAGGAAGATGGCTTTGCCGAAGCGATGATGCGCTTCGT
GCTCGAGGGGAGACGCTGA

Upstream 100 bases:

>100_bases
GCGGCAGCGCGGGACCGGATGCGGCGGACAAGCTGCTTGCGGATGATGAGCCGACGCGGCGCTGGCGACCGGTCGCGCTC
GATCCGGCGGAGAGCGGGCA

Downstream 100 bases:

>100_bases
TGAAACCTGTGCGTGGCGAACTCGTCGTCGTGCCCGATGCGAAAGCCTTCGCCGAATACGGAGCGCGCCTCTTTGCGGAA
GAGGCCGCCGCCGCGCGCGG

Product: Cof-like hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MSRAVDLVIADVDGTLVTNDKRLTAATKLAVDALREAGIRFAITSGRPPRGMRMLSEPLAIDTPLAGFNGGVMMAPDFSR
VVASHDLQDDVIGKAIDLLDDHGLDAWVYTHDRWLVRDAAAPHVDREQRTVAFEPETVERYDVSSLHGVVKIVGVTDDAE
RMKSCLAAAHKAFGDGVTADCSQPYYLDITSAHANKGAVVDAMSSELGIPHERIATIGDMPNDVAMFARSGLSIAMGNAD
DSVKRKADHATRGNEEDGFAEAMMRFVLEGRR

Sequences:

>Translated_272_residues
MSRAVDLVIADVDGTLVTNDKRLTAATKLAVDALREAGIRFAITSGRPPRGMRMLSEPLAIDTPLAGFNGGVMMAPDFSR
VVASHDLQDDVIGKAIDLLDDHGLDAWVYTHDRWLVRDAAAPHVDREQRTVAFEPETVERYDVSSLHGVVKIVGVTDDAE
RMKSCLAAAHKAFGDGVTADCSQPYYLDITSAHANKGAVVDAMSSELGIPHERIATIGDMPNDVAMFARSGLSIAMGNAD
DSVKRKADHATRGNEEDGFAEAMMRFVLEGRR
>Mature_271_residues
SRAVDLVIADVDGTLVTNDKRLTAATKLAVDALREAGIRFAITSGRPPRGMRMLSEPLAIDTPLAGFNGGVMMAPDFSRV
VASHDLQDDVIGKAIDLLDDHGLDAWVYTHDRWLVRDAAAPHVDREQRTVAFEPETVERYDVSSLHGVVKIVGVTDDAER
MKSCLAAAHKAFGDGVTADCSQPYYLDITSAHANKGAVVDAMSSELGIPHERIATIGDMPNDVAMFARSGLSIAMGNADD
SVKRKADHATRGNEEDGFAEAMMRFVLEGRR

Specific function: Unknown

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI2367265, Length=284, Percent_Identity=30.6338028169014, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786982, Length=276, Percent_Identity=26.0869565217391, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI48994981, Length=244, Percent_Identity=25, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: NA

Molecular weight: Translated: 29376; Mature: 29245

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS01228 COF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRAVDLVIADVDGTLVTNDKRLTAATKLAVDALREAGIRFAITSGRPPRGMRMLSEPLA
CCCEEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHCCCC
IDTPLAGFNGGVMMAPDFSRVVASHDLQDDVIGKAIDLLDDHGLDAWVYTHDRWLVRDAA
CCCCCCCCCCCEEECCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCEEEEECCC
APHVDREQRTVAFEPETVERYDVSSLHGVVKIVGVTDDAERMKSCLAAAHKAFGDGVTAD
CCCCCCCCCEEEECCCHHHHHCHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCC
CSQPYYLDITSAHANKGAVVDAMSSELGIPHERIATIGDMPNDVAMFARSGLSIAMGNAD
CCCCEEEEEECCCCCCCCEEEEHHHHCCCCHHHHHHHCCCCHHHHHHHHCCCEEEECCCC
DSVKRKADHATRGNEEDGFAEAMMRFVLEGRR
HHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRAVDLVIADVDGTLVTNDKRLTAATKLAVDALREAGIRFAITSGRPPRGMRMLSEPLA
CCEEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHCCCC
IDTPLAGFNGGVMMAPDFSRVVASHDLQDDVIGKAIDLLDDHGLDAWVYTHDRWLVRDAA
CCCCCCCCCCCEEECCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCEEEEECCC
APHVDREQRTVAFEPETVERYDVSSLHGVVKIVGVTDDAERMKSCLAAAHKAFGDGVTAD
CCCCCCCCCEEEECCCHHHHHCHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCC
CSQPYYLDITSAHANKGAVVDAMSSELGIPHERIATIGDMPNDVAMFARSGLSIAMGNAD
CCCCEEEEEECCCCCCCCEEEEHHHHCCCCHHHHHHHCCCCHHHHHHHHCCCEEEECCCC
DSVKRKADHATRGNEEDGFAEAMMRFVLEGRR
HHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9025291; 9384377 [H]