Click here to switch to the map view.

The map label for this gene is rpiA [H]

Identifier: 148260275

GI number: 148260275

Start: 1419870

End: 1421144

Strand: Reverse

Name: rpiA [H]

Synonym: Acry_1272

Alternate gene names: 148260275

Gene position: 1421144-1419870 (Counterclockwise)

Preceding gene: 148260276

Following gene: 148260274

Centisome position: 41.93

GC content: 66.67

Gene sequence:

>1275_bases
ATGGGAACCGATTTCGAAAATGGCAAGCGTGCGGCCGCGCGGCTGGCCGTCGGTCTCGTCGAATCCGGAATGCGCGTGGG
CCTCGGCACGGGGTCGACCGCCGCCCATTTCATCGATCAGCTCGGCGCGCGCGTCCGCGCCGAAGGGCTCGACATCGAAT
GCGTCGCGACATCCGATCTCACGGCAGCCAGGGCGGAGTTCCTCGGCCTGCGCCTCGTGCCGCTCGATGGTTCCCTCGAC
CTTGCGGTTGACGGAGCCGATGAGGTGGAGTTCGGAACGCTCCGCCTGATCAAGGGGCTGGGTGGTGCCCTGCTGCGGGA
AAAGCTGGTGGCGCAATCGGCACGGCGCTTTGTCGTCATCGCCGACCGGAGCAAGCTGGTGACACGGCTCGGCGCGCATT
CGAAACTGCCAGTCGAGATCGTCCGCCATGGCGCGGACCGCACCTGTGCCAGGCTCGCCGAACTGGATCTTGCGCCCGTT
CTGCGCGCGAATGCCGGCAGTCCCTTCGTTTCGGATGGCGGCCACTTCATTGCCGATTGCACCATGCCGAAAGGCATCGT
GCCCGAAGCCGTCGAGTCTGCCCTCCGCTCGATTGCCGGCGTTGTCGGCACCGGCCTCTTCCTGTCGGGTTCCGCCTGCG
CGATCATTGGCTATCCCGATGGCTCGACCCGCCAGTTCGATGGCGACGCGGTCTCCGCGGCCGGCCTCGCACCCGCCGCG
GCCACGCTGCGTTGCCTCGGCCTGCCGAAGCCGGACATTCCGCCACTGATCGCCGTGATGGGTGTTTCCGCATCCGGCAA
ATCCACGATCGGGCTTTTGCTGGCGGAACTTCTGGGCGTGCCGTTCTGCGATGGCGACGATCTGCATCCGGAGTCGAACC
GTGAGAAAATGCACTCCGGCCGCCCGCTCGACGATGAAGACAGGATGCCCTGGCTGCATCGCATCGCCATGCGCCTTGCG
GAATGGCGGACGAGACGATGCGGCGGCGTCATTGTCAGCTCGCTTCTGACGCGGCGTTATCGCGATCTGGTGCGCGGCGG
TGCGGGCCCGTTCACGCTGGTGCATCTCGATGGATCGCGCGATCTGCTGGCCGCGCGCATCGCCGCACGGCGCGGTCACT
TCATGCCGGCATCCCTGCTCGACAGCCAGCTCGCCGCGCTCGAGCCGCCGCAGGCCGGAGAGGATGCGATTGTCGTCTCG
ATCGATGAGTCTCCCGTCGGCATCGTGCGGAGCATCATGCGGTCGCTGCAGGCTGGCCAGGTTTCAGCAAACTAG

Upstream 100 bases:

>100_bases
GTGACGTGCCCGCCGCCCGCCTCAGGCCGGTCGGACGCCTGATCTGGCTCGCGGATCGCGATGCCGCCGGACGATGGGCG
GACTGAAGGGGGCACATCGC

Downstream 100 bases:

>100_bases
CGAGGGGAGGGCGCGATGAGCCTGAGAATCGAGGATTACGCAATCATCGGAGACCGGCAGACAGCGGCCCTTGTCGGCAA
GGACGGCTCGATCGATTTTC

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MGTDFENGKRAAARLAVGLVESGMRVGLGTGSTAAHFIDQLGARVRAEGLDIECVATSDLTAARAEFLGLRLVPLDGSLD
LAVDGADEVEFGTLRLIKGLGGALLREKLVAQSARRFVVIADRSKLVTRLGAHSKLPVEIVRHGADRTCARLAELDLAPV
LRANAGSPFVSDGGHFIADCTMPKGIVPEAVESALRSIAGVVGTGLFLSGSACAIIGYPDGSTRQFDGDAVSAAGLAPAA
ATLRCLGLPKPDIPPLIAVMGVSASGKSTIGLLLAELLGVPFCDGDDLHPESNREKMHSGRPLDDEDRMPWLHRIAMRLA
EWRTRRCGGVIVSSLLTRRYRDLVRGGAGPFTLVHLDGSRDLLAARIAARRGHFMPASLLDSQLAALEPPQAGEDAIVVS
IDESPVGIVRSIMRSLQAGQVSAN

Sequences:

>Translated_424_residues
MGTDFENGKRAAARLAVGLVESGMRVGLGTGSTAAHFIDQLGARVRAEGLDIECVATSDLTAARAEFLGLRLVPLDGSLD
LAVDGADEVEFGTLRLIKGLGGALLREKLVAQSARRFVVIADRSKLVTRLGAHSKLPVEIVRHGADRTCARLAELDLAPV
LRANAGSPFVSDGGHFIADCTMPKGIVPEAVESALRSIAGVVGTGLFLSGSACAIIGYPDGSTRQFDGDAVSAAGLAPAA
ATLRCLGLPKPDIPPLIAVMGVSASGKSTIGLLLAELLGVPFCDGDDLHPESNREKMHSGRPLDDEDRMPWLHRIAMRLA
EWRTRRCGGVIVSSLLTRRYRDLVRGGAGPFTLVHLDGSRDLLAARIAARRGHFMPASLLDSQLAALEPPQAGEDAIVVS
IDESPVGIVRSIMRSLQAGQVSAN
>Mature_423_residues
GTDFENGKRAAARLAVGLVESGMRVGLGTGSTAAHFIDQLGARVRAEGLDIECVATSDLTAARAEFLGLRLVPLDGSLDL
AVDGADEVEFGTLRLIKGLGGALLREKLVAQSARRFVVIADRSKLVTRLGAHSKLPVEIVRHGADRTCARLAELDLAPVL
RANAGSPFVSDGGHFIADCTMPKGIVPEAVESALRSIAGVVGTGLFLSGSACAIIGYPDGSTRQFDGDAVSAAGLAPAAA
TLRCLGLPKPDIPPLIAVMGVSASGKSTIGLLLAELLGVPFCDGDDLHPESNREKMHSGRPLDDEDRMPWLHRIAMRLAE
WRTRRCGGVIVSSLLTRRYRDLVRGGAGPFTLVHLDGSRDLLAARIAARRGHFMPASLLDSQLAALEPPQAGEDAIVVSI
DESPVGIVRSIMRSLQAGQVSAN

Specific function: Gluconate utilization system GNT-II. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=185, Percent_Identity=42.1621621621622, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI94536842, Length=231, Percent_Identity=36.7965367965368, Blast_Score=119, Evalue=6e-27,
Organism=Escherichia coli, GI1790719, Length=140, Percent_Identity=48.5714285714286, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI87082265, Length=168, Percent_Identity=41.0714285714286, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789280, Length=217, Percent_Identity=40.5529953917051, Blast_Score=122, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25146487, Length=168, Percent_Identity=43.452380952381, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17551758, Length=235, Percent_Identity=34.8936170212766, Blast_Score=106, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320454, Length=158, Percent_Identity=36.0759493670886, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324669, Length=245, Percent_Identity=32.2448979591837, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281364072, Length=223, Percent_Identity=33.1838565022422, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 44488; Mature: 44357

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTDFENGKRAAARLAVGLVESGMRVGLGTGSTAAHFIDQLGARVRAEGLDIECVATSDL
CCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHEECCCCCEEEEECCCC
TAARAEFLGLRLVPLDGSLDLAVDGADEVEFGTLRLIKGLGGALLREKLVAQSARRFVVI
HHHHHHHHCEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEE
ADRSKLVTRLGAHSKLPVEIVRHGADRTCARLAELDLAPVLRANAGSPFVSDGGHFIADC
ECHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHCCHHHHHHCCCCCCCCCCCCCEEEEC
TMPKGIVPEAVESALRSIAGVVGTGLFLSGSACAIIGYPDGSTRQFDGDAVSAAGLAPAA
CCCCCCCHHHHHHHHHHHHHHHHCCCEECCCEEEEEECCCCCCCCCCCCCCCCCCCCHHH
ATLRCLGLPKPDIPPLIAVMGVSASGKSTIGLLLAELLGVPFCDGDDLHPESNREKMHSG
HHHHCCCCCCCCCCHHHHHEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCC
RPLDDEDRMPWLHRIAMRLAEWRTRRCGGVIVSSLLTRRYRDLVRGGAGPFTLVHLDGSR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCH
DLLAARIAARRGHFMPASLLDSQLAALEPPQAGEDAIVVSIDESPVGIVRSIMRSLQAGQ
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCC
VSAN
CCCC
>Mature Secondary Structure 
GTDFENGKRAAARLAVGLVESGMRVGLGTGSTAAHFIDQLGARVRAEGLDIECVATSDL
CCCCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHEECCCCCEEEEECCCC
TAARAEFLGLRLVPLDGSLDLAVDGADEVEFGTLRLIKGLGGALLREKLVAQSARRFVVI
HHHHHHHHCEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEE
ADRSKLVTRLGAHSKLPVEIVRHGADRTCARLAELDLAPVLRANAGSPFVSDGGHFIADC
ECHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHCCHHHHHHCCCCCCCCCCCCCEEEEC
TMPKGIVPEAVESALRSIAGVVGTGLFLSGSACAIIGYPDGSTRQFDGDAVSAAGLAPAA
CCCCCCCHHHHHHHHHHHHHHHHCCCEECCCEEEEEECCCCCCCCCCCCCCCCCCCCHHH
ATLRCLGLPKPDIPPLIAVMGVSASGKSTIGLLLAELLGVPFCDGDDLHPESNREKMHSG
HHHHCCCCCCCCCCHHHHHEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCC
RPLDDEDRMPWLHRIAMRLAEWRTRRCGGVIVSSLLTRRYRDLVRGGAGPFTLVHLDGSR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCH
DLLAARIAARRGHFMPASLLDSQLAALEPPQAGEDAIVVSIDESPVGIVRSIMRSLQAGQ
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCC
VSAN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]