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The map label for this gene is fabG [H]

Identifier: 148260262

GI number: 148260262

Start: 1402443

End: 1403933

Strand: Reverse

Name: fabG [H]

Synonym: Acry_1259

Alternate gene names: 148260262

Gene position: 1403933-1402443 (Counterclockwise)

Preceding gene: 148260263

Following gene: 148260261

Centisome position: 41.42

GC content: 74.58

Gene sequence:

>1491_bases
ATGATGGCTGACCGCTACCTCGCCTTCGCCAACCGGCCGGTCGGCCGCTTCCTCACCGGCCGGCTGGGGCTGCCGCAGCC
CCGTCCGCTGTTGCGCCACGCCGAGGGGCAGCCCGCGGTGATCGGCCCGGTCCTCGCCGGCGCCGCCCCCGGCGGCCGTC
TCGCCGAGGCCGTGGTCGCGACCCTCGCGGGCACGCCGGCCGCGATGCTGTTCGAGGGCGATGCCGCCGACTGGCCGGGT
CTCGCCGCCCGCCACGGCGTCATGGCGGCGCGCTTCCTGCCGGGGCAGAGCGGGCGCGCCGGTTCGGCGGTGTTCGATGC
GACCGGCATCGCCGATCCGGCCGGGCTCGACGCGCTCTACACCTTCTTCCACCACTGCGTCCGCGAGATCGCGCCGGACG
GCCGCATCGTCGTCCTCGGCGCGCCGCCGGAAACCTGCGCCGACGCCGATGCAAGGGTCGCCCAGCGCGCCCTCGAAGGC
TTCACCCGCTCGCTCGGCAAGGAGGCGCGGCGCAACATCGCGGTGCAGCTCGTCCGCGTCGCCGCCGATGCCGATGCCGC
CGCGCTCGACAGCACGCTCCGCTTCTTCCTCTCCCGCCGCAGCGCCTATGTCTCGGGACAGGTCGTCCACGTCGCGGCGC
CGGTCGTGGACCTGCCCGAAGCCGCGCCGCGCGCCCATCGGGGCCGCCGCGTTCTCGTCACCGGCGCCGCCCGCGGCATC
GGTGCCGCCATCGCCGAAGCCTTCGCCCGCGAAGGGGCGAAGGTCGTCGCCCTCGACGTGCCCCAGGCCGGGGCCGACTT
GCTTTCCCTCGCCCAGCGCCTCGGCGGCAGCCGCCTCGCCCTCGACATCACCGATCCCGCTTCGGATGCCGCGATCCTCG
AGGACGCCGCGACCCATGGCGGCTACGACGTCGTCGTCCATAATGCCGGCATCACCCGCGACCGCACCATCGCCCGCATG
AGCCGCGCCGAATGGGACCAGGTCATGCAGGTCAACCTGCTGGCCCCGCTGCGCATCACCGAAGCCCTGCTCGGCGCCGG
CGCGCTCGGGCCCAACGGCCGCATCGTCGGCGTCTCCTCGATCGCCGGGATCGCCGGCAATCTCGGCCAGACCAACTATG
CCGCGACCAAGGCCGGCGTGATCGGCATGGTCGATGCGCTCGCCCCGCGCCTTGCCGCGCGCGGGGCCACGATCAACGCC
GTCGCCCCCGGCTTCATCGAGACCCGGATGACCGCCGCCATCCCCTTCGCCATCCGCGAGGCCGGACGGCGGATGAACGC
GATGGGGGCAGGGCGGCCTGCCGGAAGATGTCGCCGAGACCATCCTCTGGCTCGCCGAGCCGCGCAGCGCCGGGGTCAAC
GGCAACATCGTCCGCGTCTGCGGCCAGAGCCTGCTGGGCGCCTGAGATGGAGGCCGTCCCGATCCCGGCCGGCAACATCG
CGCCCGCGCCGGACCCCGATCCCTGGCGCGCCGCGCCGCAGGAAACGCTGA

Upstream 100 bases:

>100_bases
CCTACTGGGCCGAGCGCGATGGCGGCGAGGCGCCCGGCATCGCCCGGATCGGGAGGGGCGGCGCGAAGGTGCGGTCGTCG
CGCGCACCGACGGCGGCCGA

Downstream 100 bases:

>100_bases
AGGCCGTGCCCGCCGCCGGCGCCATCCGCCGCCGGGCCCTTGCCACGCTGCTCCGCCGCGGCGCCGCCGGCGCGCCCGAT
CCCGTGGTGCTCCGCCGCCG

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MMADRYLAFANRPVGRFLTGRLGLPQPRPLLRHAEGQPAVIGPVLAGAAPGGRLAEAVVATLAGTPAAMLFEGDAADWPG
LAARHGVMAARFLPGQSGRAGSAVFDATGIADPAGLDALYTFFHHCVREIAPDGRIVVLGAPPETCADADARVAQRALEG
FTRSLGKEARRNIAVQLVRVAADADAAALDSTLRFFLSRRSAYVSGQVVHVAAPVVDLPEAAPRAHRGRRVLVTGAARGI
GAAIAEAFAREGAKVVALDVPQAGADLLSLAQRLGGSRLALDITDPASDAAILEDAATHGGYDVVVHNAGITRDRTIARM
SRAEWDQVMQVNLLAPLRITEALLGAGALGPNGRIVGVSSIAGIAGNLGQTNYAATKAGVIGMVDALAPRLAARGATINA
VAPGFIETRMTAAIPFAIREAGRRMNAMGAGRPAGRCRRDHPLARRAAQRRGQRQHRPRLRPEPAGRLRWRPSRSRPATS
RPRRTPIPGAPRRRKR

Sequences:

>Translated_496_residues
MMADRYLAFANRPVGRFLTGRLGLPQPRPLLRHAEGQPAVIGPVLAGAAPGGRLAEAVVATLAGTPAAMLFEGDAADWPG
LAARHGVMAARFLPGQSGRAGSAVFDATGIADPAGLDALYTFFHHCVREIAPDGRIVVLGAPPETCADADARVAQRALEG
FTRSLGKEARRNIAVQLVRVAADADAAALDSTLRFFLSRRSAYVSGQVVHVAAPVVDLPEAAPRAHRGRRVLVTGAARGI
GAAIAEAFAREGAKVVALDVPQAGADLLSLAQRLGGSRLALDITDPASDAAILEDAATHGGYDVVVHNAGITRDRTIARM
SRAEWDQVMQVNLLAPLRITEALLGAGALGPNGRIVGVSSIAGIAGNLGQTNYAATKAGVIGMVDALAPRLAARGATINA
VAPGFIETRMTAAIPFAIREAGRRMNAMGAGRPAGRCRRDHPLARRAAQRRGQRQHRPRLRPEPAGRLRWRPSRSRPATS
RPRRTPIPGAPRRRKR
>Mature_496_residues
MMADRYLAFANRPVGRFLTGRLGLPQPRPLLRHAEGQPAVIGPVLAGAAPGGRLAEAVVATLAGTPAAMLFEGDAADWPG
LAARHGVMAARFLPGQSGRAGSAVFDATGIADPAGLDALYTFFHHCVREIAPDGRIVVLGAPPETCADADARVAQRALEG
FTRSLGKEARRNIAVQLVRVAADADAAALDSTLRFFLSRRSAYVSGQVVHVAAPVVDLPEAAPRAHRGRRVLVTGAARGI
GAAIAEAFAREGAKVVALDVPQAGADLLSLAQRLGGSRLALDITDPASDAAILEDAATHGGYDVVVHNAGITRDRTIARM
SRAEWDQVMQVNLLAPLRITEALLGAGALGPNGRIVGVSSIAGIAGNLGQTNYAATKAGVIGMVDALAPRLAARGATINA
VAPGFIETRMTAAIPFAIREAGRRMNAMGAGRPAGRCRRDHPLARRAAQRRGQRQHRPRLRPEPAGRLRWRPSRSRPATS
RPRRTPIPGAPRRRKR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=215, Percent_Identity=38.6046511627907, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI4504505, Length=203, Percent_Identity=35.4679802955665, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI40254992, Length=182, Percent_Identity=34.6153846153846, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=32.1782178217822, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI4758504, Length=212, Percent_Identity=29.7169811320755, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI32483357, Length=189, Percent_Identity=31.2169312169312, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI20149619, Length=222, Percent_Identity=29.7297297297297, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI66933014, Length=182, Percent_Identity=32.4175824175824, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI142976729, Length=230, Percent_Identity=24.7826086956522, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI83715985, Length=192, Percent_Identity=30.2083333333333, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI40807363, Length=191, Percent_Identity=27.2251308900524, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI7705925, Length=210, Percent_Identity=30.4761904761905, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI224922801, Length=179, Percent_Identity=30.7262569832402, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=191, Percent_Identity=46.0732984293194, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI87082100, Length=194, Percent_Identity=35.5670103092784, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1790717, Length=191, Percent_Identity=28.7958115183246, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789208, Length=189, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87082160, Length=190, Percent_Identity=25.7894736842105, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367365, Length=190, Percent_Identity=33.1578947368421, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI2367175, Length=193, Percent_Identity=32.6424870466321, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786812, Length=223, Percent_Identity=28.2511210762332, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786701, Length=195, Percent_Identity=29.7435897435897, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789378, Length=241, Percent_Identity=27.8008298755187, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=192, Percent_Identity=42.1875, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17555706, Length=202, Percent_Identity=40.0990099009901, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17538182, Length=213, Percent_Identity=30.5164319248826, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=212, Percent_Identity=30.188679245283, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=200, Percent_Identity=32, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=194, Percent_Identity=28.3505154639175, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=189, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=196, Percent_Identity=30.6122448979592, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=211, Percent_Identity=27.9620853080569, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=203, Percent_Identity=31.5270935960591, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=211, Percent_Identity=32.2274881516588, Blast_Score=93, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6322227, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639444, Length=200, Percent_Identity=36.5, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI18859837, Length=199, Percent_Identity=34.6733668341709, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI23397609, Length=211, Percent_Identity=34.5971563981043, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644339, Length=195, Percent_Identity=35.8974358974359, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17737361, Length=205, Percent_Identity=31.219512195122, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357041, Length=191, Percent_Identity=30.8900523560209, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21358495, Length=254, Percent_Identity=26.3779527559055, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28571526, Length=191, Percent_Identity=31.413612565445, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24643142, Length=186, Percent_Identity=32.258064516129, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355319, Length=194, Percent_Identity=29.3814432989691, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581726, Length=198, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 52102; Mature: 52102

Theoretical pI: Translated: 12.02; Mature: 12.02

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMADRYLAFANRPVGRFLTGRLGLPQPRPLLRHAEGQPAVIGPVLAGAAPGGRLAEAVVA
CCCCHHHHHHCCCHHHHHHCCCCCCCCCHHHHCCCCCCCEEHHHHHCCCCCHHHHHHHHH
TLAGTPAAMLFEGDAADWPGLAARHGVMAARFLPGQSGRAGSAVFDATGIADPAGLDALY
HHCCCCEEEEEECCCCCCCCHHHHHHHHHEEECCCCCCCCCCEEEECCCCCCCCHHHHHH
TFFHHCVREIAPDGRIVVLGAPPETCADADARVAQRALEGFTRSLGKEARRNIAVQLVRV
HHHHHHHHHHCCCCEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AADADAAALDSTLRFFLSRRSAYVSGQVVHVAAPVVDLPEAAPRAHRGRRVLVTGAARGI
HCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHCCCEEEEECCCHHH
GAAIAEAFAREGAKVVALDVPQAGADLLSLAQRLGGSRLALDITDPASDAAILEDAATHG
HHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCC
GYDVVVHNAGITRDRTIARMSRAEWDQVMQVNLLAPLRITEALLGAGALGPNGRIVGVSS
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEHH
IAGIAGNLGQTNYAATKAGVIGMVDALAPRLAARGATINAVAPGFIETRMTAAIPFAIRE
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHH
AGRRMNAMGAGRPAGRCRRDHPLARRAAQRRGQRQHRPRLRPEPAGRLRWRPSRSRPATS
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCC
RPRRTPIPGAPRRRKR
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMADRYLAFANRPVGRFLTGRLGLPQPRPLLRHAEGQPAVIGPVLAGAAPGGRLAEAVVA
CCCCHHHHHHCCCHHHHHHCCCCCCCCCHHHHCCCCCCCEEHHHHHCCCCCHHHHHHHHH
TLAGTPAAMLFEGDAADWPGLAARHGVMAARFLPGQSGRAGSAVFDATGIADPAGLDALY
HHCCCCEEEEEECCCCCCCCHHHHHHHHHEEECCCCCCCCCCEEEECCCCCCCCHHHHHH
TFFHHCVREIAPDGRIVVLGAPPETCADADARVAQRALEGFTRSLGKEARRNIAVQLVRV
HHHHHHHHHHCCCCEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AADADAAALDSTLRFFLSRRSAYVSGQVVHVAAPVVDLPEAAPRAHRGRRVLVTGAARGI
HCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHCCCEEEEECCCHHH
GAAIAEAFAREGAKVVALDVPQAGADLLSLAQRLGGSRLALDITDPASDAAILEDAATHG
HHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCC
GYDVVVHNAGITRDRTIARMSRAEWDQVMQVNLLAPLRITEALLGAGALGPNGRIVGVSS
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEHH
IAGIAGNLGQTNYAATKAGVIGMVDALAPRLAARGATINAVAPGFIETRMTAAIPFAIRE
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHH
AGRRMNAMGAGRPAGRCRRDHPLARRAAQRRGQRQHRPRLRPEPAGRLRWRPSRSRPATS
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCC
RPRRTPIPGAPRRRKR
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]