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The map label for this gene is ctaA2

Identifier: 148260228

GI number: 148260228

Start: 1364140

End: 1365243

Strand: Reverse

Name: ctaA2

Synonym: Acry_1225

Alternate gene names: 148260228

Gene position: 1365243-1364140 (Counterclockwise)

Preceding gene: 148260233

Following gene: 148260227

Centisome position: 40.28

GC content: 68.66

Gene sequence:

>1104_bases
ATGGCATCGCAATCGGTGGCGGGTATCGGCGGCAGGACGGCGGCGGGCGAGGCGCGGGCGGCGAGCCCGGAAAGCCGGCG
GATGGTCGCGATCTGGCTGTTCGTCAGCTTCGCGCTGATCGTCGAGATGTTCGGGATCGGCGCCTATGTGCAGAACATGA
ACGCCGGCCTGTCGATCATGGCGTGGCAGCCGGTCTCGGGCGTGATCCCGCCGCTGACCCATGCGGCGTGGGAGCGGATG
TTCGCGCTCTACAAGACGATTCCGCAATACAAGGAGCTCAATCGCGGCATGGACCTCGCCGGGTTCAAGGCGATCTTCTG
GCCGGAATGGATCCACCGGATGTGGGGGCGGCTGCTCGGCTTCGACTTCGGCGTGCCGCTGGTCTGGTTCCTCTGGACCG
GGCGGATCGAGCGGCGGCTGCGGCCCTGGCTGGTGACGCTGTTCGTCCTGGGCGGGGTGCAGGGGCTGATCGGCTGGTGG
ATGGTCGCCTCCGGCTTCCAGCCGGGGCTGACCGAGGTGTCGGTGTTCCGGCTCTCGGTGCATTACTGTTTCGCCACCCT
GCTCGCCATCGCCGTGTTCGCCACCGCGCTGACCGTGCTGAAGCCGGCCGAGACGCGGCTGCCGCCGGAGGAGGCCGCGC
GCTATGCGGGGGCGCGGCGGATGGCGATGGGCTCGATCGTGCTGATCTCGATCGCCATCGTGGCGGGGACGTTCCTCTCG
GGCACGCATGCCTACACGATCGACAACACCTTCCCGCTGATGCAGGGGCGCTGGGTGCCGCCGGATTACGCGGCGCTGCA
CCCGTTCTGGAAGAATTTCTTCCTCAACAAGGCGGCGACGCAGTTCGACCACCGGCTGCTCGGCACGGTGGCGGCGGTGG
GCGTGCTGGCGGCGGTGGTGGCGGCGATCCGCGCCGACCTGCCGGCGCGGGCGCGCGATGCGTTCCTGGTGATGGGCGCG
CTGCTGATCGTGCAGTATATTCTCGGCGTGACCACGCTCGTCTCCAAGATTCTCGATATCGGCATCGTGCACCAGCTCAA
CGCGGTGCTGCTGCTGGCCGCCGCGGTGTGGGCCTGGTTCGAGCTGCGCGGGCGGCCGGCATGA

Upstream 100 bases:

>100_bases
AGATTGCTCGATGGAACAAGGTGGGCGGGCGCGCGGGTTTACAAGCGGGGTTTCGGGTGCAAATCGGGGGGCAGGATCGG
CAGAGTCGGGATTTGGACTG

Downstream 100 bases:

>100_bases
GCGGTGCGGCGGCGCGGGGGGACCGGCTGGTCGGCACCTGGCTGCTCGTCATCTGCTTCATGATCTTCGGCATGGTGGTG
GGCGGCGGCCATGCGCGGAC

Product: cytochrome oxidase assembly

Products: NA

Alternate protein names: HAS 2; Cytochrome aa3-controlling protein 2

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MASQSVAGIGGRTAAGEARAASPESRRMVAIWLFVSFALIVEMFGIGAYVQNMNAGLSIMAWQPVSGVIPPLTHAAWERM
FALYKTIPQYKELNRGMDLAGFKAIFWPEWIHRMWGRLLGFDFGVPLVWFLWTGRIERRLRPWLVTLFVLGGVQGLIGWW
MVASGFQPGLTEVSVFRLSVHYCFATLLAIAVFATALTVLKPAETRLPPEEAARYAGARRMAMGSIVLISIAIVAGTFLS
GTHAYTIDNTFPLMQGRWVPPDYAALHPFWKNFFLNKAATQFDHRLLGTVAAVGVLAAVVAAIRADLPARARDAFLVMGA
LLIVQYILGVTTLVSKILDIGIVHQLNAVLLLAAAVWAWFELRGRPA

Sequences:

>Translated_367_residues
MASQSVAGIGGRTAAGEARAASPESRRMVAIWLFVSFALIVEMFGIGAYVQNMNAGLSIMAWQPVSGVIPPLTHAAWERM
FALYKTIPQYKELNRGMDLAGFKAIFWPEWIHRMWGRLLGFDFGVPLVWFLWTGRIERRLRPWLVTLFVLGGVQGLIGWW
MVASGFQPGLTEVSVFRLSVHYCFATLLAIAVFATALTVLKPAETRLPPEEAARYAGARRMAMGSIVLISIAIVAGTFLS
GTHAYTIDNTFPLMQGRWVPPDYAALHPFWKNFFLNKAATQFDHRLLGTVAAVGVLAAVVAAIRADLPARARDAFLVMGA
LLIVQYILGVTTLVSKILDIGIVHQLNAVLLLAAAVWAWFELRGRPA
>Mature_366_residues
ASQSVAGIGGRTAAGEARAASPESRRMVAIWLFVSFALIVEMFGIGAYVQNMNAGLSIMAWQPVSGVIPPLTHAAWERMF
ALYKTIPQYKELNRGMDLAGFKAIFWPEWIHRMWGRLLGFDFGVPLVWFLWTGRIERRLRPWLVTLFVLGGVQGLIGWWM
VASGFQPGLTEVSVFRLSVHYCFATLLAIAVFATALTVLKPAETRLPPEEAARYAGARRMAMGSIVLISIAIVAGTFLSG
THAYTIDNTFPLMQGRWVPPDYAALHPFWKNFFLNKAATQFDHRLLGTVAAVGVLAAVVAAIRADLPARARDAFLVMGAL
LIVQYILGVTTLVSKILDIGIVHQLNAVLLLAAAVWAWFELRGRPA

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=368, Percent_Identity=31.25, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI17921987, Length=345, Percent_Identity=31.0144927536232, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17536069, Length=359, Percent_Identity=31.1977715877437, Blast_Score=165, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6320989, Length=363, Percent_Identity=31.129476584022, Blast_Score=157, Evalue=2e-39,
Organism=Drosophila melanogaster, GI19922860, Length=351, Percent_Identity=31.3390313390313, Blast_Score=168, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA2_ACICJ (A5FXV4)

Other databases:

- EMBL:   CP000697
- RefSeq:   YP_001234355.1
- STRING:   A5FXV4
- GeneID:   5159963
- GenomeReviews:   CP000697_GR
- KEGG:   acr:Acry_1225
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- OMA:   GLSIVEW
- BioCyc:   ACRY349163:ACRY_1225-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 40382; Mature: 40251

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: NA

Important sites: BINDING 344-344

Signals:

None

Transmembrane regions:

HASH(0x14945018)-; HASH(0x14cbb474)-; HASH(0x147570f0)-; HASH(0x1478d28c)-; HASH(0x14921d74)-; HASH(0x149d7e10)-; HASH(0x14541e10)-; HASH(0x14c69d14)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASQSVAGIGGRTAAGEARAASPESRRMVAIWLFVSFALIVEMFGIGAYVQNMNAGLSIM
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
AWQPVSGVIPPLTHAAWERMFALYKTIPQYKELNRGMDLAGFKAIFWPEWIHRMWGRLLG
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
FDFGVPLVWFLWTGRIERRLRPWLVTLFVLGGVQGLIGWWMVASGFQPGLTEVSVFRLSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
HYCFATLLAIAVFATALTVLKPAETRLPPEEAARYAGARRMAMGSIVLISIAIVAGTFLS
HHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTHAYTIDNTFPLMQGRWVPPDYAALHPFWKNFFLNKAATQFDHRLLGTVAAVGVLAAVV
CCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIRADLPARARDAFLVMGALLIVQYILGVTTLVSKILDIGIVHQLNAVLLLAAAVWAWF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRGRPA
HHCCCCH
>Mature Secondary Structure 
ASQSVAGIGGRTAAGEARAASPESRRMVAIWLFVSFALIVEMFGIGAYVQNMNAGLSIM
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
AWQPVSGVIPPLTHAAWERMFALYKTIPQYKELNRGMDLAGFKAIFWPEWIHRMWGRLLG
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
FDFGVPLVWFLWTGRIERRLRPWLVTLFVLGGVQGLIGWWMVASGFQPGLTEVSVFRLSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
HYCFATLLAIAVFATALTVLKPAETRLPPEEAARYAGARRMAMGSIVLISIAIVAGTFLS
HHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTHAYTIDNTFPLMQGRWVPPDYAALHPFWKNFFLNKAATQFDHRLLGTVAAVGVLAAVV
CCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIRADLPARARDAFLVMGALLIVQYILGVTTLVSKILDIGIVHQLNAVLLLAAAVWAWF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRGRPA
HHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA