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The map label for this gene is cysQ [H]

Identifier: 148260207

GI number: 148260207

Start: 1338445

End: 1339215

Strand: Reverse

Name: cysQ [H]

Synonym: Acry_1203

Alternate gene names: 148260207

Gene position: 1339215-1338445 (Counterclockwise)

Preceding gene: 148260210

Following gene: 148260205

Centisome position: 39.51

GC content: 70.56

Gene sequence:

>771_bases
ATGAACGACAATCAACTGCTCGAACTCGCAGCCTCGCTGGCCGAGGCCGCGGGGCGCGAAATCCTTGCCGTCCGTGCCGG
CGGCTTCACCGTTGACCGCAAGGCCGACGAAACCCCGGTGACGATCGCCGACACGCGCGCCGAACGGGTGATCGTCGAGG
GGTTGCGCCGTGCCGTCCCCGAGATCCCGGTGGTTGCCGAGGAAGAAGTCGCCGCTGGCCGGCAGACCGATCCCGGCCGC
CGCTTCTGGCTGGTCGATCCGCTCGACGGCACGCGGGAATTCGCCGAGGGGCGCGACGAGTTCGCGGTCTGCATCGGCCT
TGTGGTCGATGGCCGGCCGCATCTCGGCGCGGTCGGCGCGCCGGCGCAGGGTGCCGTCTATGGCGGGATCGTGGGGAAGG
GGGCCTGGCGGCAGAACGGTGCCGGCCGCCACCCGATTGCCGCCCGCACCCCGCCGGCGGAGGGGATCACCGTCTATGCA
TCTCGCCATTACGCGGACGATCCGCAACTCGCCGCCTATCTCGCCCGCTACAAGGTAGCGAAGCTGACGAATATCGGCTC
GGCGCTGAAATTCTGCCGCCTCGCCGAGGGCGCGGCCGATTTCTACCCCCGCCTCGGCCGGACCATGGAGTGGGACACCG
CGGCGCCGCAGGCGGTGCTGGAGGCGGCGGGTGGCCGCGTCGTCACCATGGCGGACGAAACCCCCCTCCGTTACGGCAAG
AAGGGGTTCGAGAACCCCCACTTCCTCTGCTTCGGCCGCGCCGCCGGCTGA

Upstream 100 bases:

>100_bases
TCGATCATGCCGTCTTGTCCCGTTTTCCGTTTCGTTTAGCGACGCAATCCAGCATGCTCGCCAATTTGGTGTTTTCCAAG
CCCCGGGATATCAGGCGGGC

Downstream 100 bases:

>100_bases
AGGCCTGGCTCAGGGCGCCGGCCAGAGCCAGGCCGCGCCCCGCACGCCCGAGGAATCGCCGTGCTTGTTGCGGACCACCG
GCGTGTCGAACGTGTCGCTG

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNDNQLLELAASLAEAAGREILAVRAGGFTVDRKADETPVTIADTRAERVIVEGLRRAVPEIPVVAEEEVAAGRQTDPGR
RFWLVDPLDGTREFAEGRDEFAVCIGLVVDGRPHLGAVGAPAQGAVYGGIVGKGAWRQNGAGRHPIAARTPPAEGITVYA
SRHYADDPQLAAYLARYKVAKLTNIGSALKFCRLAEGAADFYPRLGRTMEWDTAAPQAVLEAAGGRVVTMADETPLRYGK
KGFENPHFLCFGRAAG

Sequences:

>Translated_256_residues
MNDNQLLELAASLAEAAGREILAVRAGGFTVDRKADETPVTIADTRAERVIVEGLRRAVPEIPVVAEEEVAAGRQTDPGR
RFWLVDPLDGTREFAEGRDEFAVCIGLVVDGRPHLGAVGAPAQGAVYGGIVGKGAWRQNGAGRHPIAARTPPAEGITVYA
SRHYADDPQLAAYLARYKVAKLTNIGSALKFCRLAEGAADFYPRLGRTMEWDTAAPQAVLEAAGGRVVTMADETPLRYGK
KGFENPHFLCFGRAAG
>Mature_256_residues
MNDNQLLELAASLAEAAGREILAVRAGGFTVDRKADETPVTIADTRAERVIVEGLRRAVPEIPVVAEEEVAAGRQTDPGR
RFWLVDPLDGTREFAEGRDEFAVCIGLVVDGRPHLGAVGAPAQGAVYGGIVGKGAWRQNGAGRHPIAARTPPAEGITVYA
SRHYADDPQLAAYLARYKVAKLTNIGSALKFCRLAEGAADFYPRLGRTMEWDTAAPQAVLEAAGGRVVTMADETPLRYGK
KGFENPHFLCFGRAAG

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=197, Percent_Identity=30.4568527918782, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1790659, Length=212, Percent_Identity=42.4528301886792, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788882, Length=200, Percent_Identity=29.5, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17537869, Length=267, Percent_Identity=28.0898876404494, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193202572, Length=209, Percent_Identity=29.1866028708134, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71995897, Length=281, Percent_Identity=25.6227758007117, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71995905, Length=281, Percent_Identity=25.6227758007117, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193202570, Length=209, Percent_Identity=28.2296650717703, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324508, Length=318, Percent_Identity=25.7861635220126, Blast_Score=83, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641722, Length=270, Percent_Identity=29.6296296296296, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24664922, Length=197, Percent_Identity=29.4416243654822, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21357329, Length=235, Percent_Identity=28.5106382978723, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 27338; Mature: 27338

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDNQLLELAASLAEAAGREILAVRAGGFTVDRKADETPVTIADTRAERVIVEGLRRAVP
CCCHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCCCCCEEEECCHHHHHHHHHHHHHCC
EIPVVAEEEVAAGRQTDPGRRFWLVDPLDGTREFAEGRDEFAVCIGLVVDGRPHLGAVGA
CCCCEECHHHHCCCCCCCCCEEEEECCCCCHHHHHCCCCCEEEEEEEEECCCCCCCCCCC
PAQGAVYGGIVGKGAWRQNGAGRHPIAARTPPAEGITVYASRHYADDPQLAAYLARYKVA
CCCCCEECCEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
KLTNIGSALKFCRLAEGAADFYPRLGRTMEWDTAAPQAVLEAAGGRVVTMADETPLRYGK
HHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEEECCCCHHHCC
KGFENPHFLCFGRAAG
CCCCCCCEEEEECCCC
>Mature Secondary Structure
MNDNQLLELAASLAEAAGREILAVRAGGFTVDRKADETPVTIADTRAERVIVEGLRRAVP
CCCHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCCCCCEEEECCHHHHHHHHHHHHHCC
EIPVVAEEEVAAGRQTDPGRRFWLVDPLDGTREFAEGRDEFAVCIGLVVDGRPHLGAVGA
CCCCEECHHHHCCCCCCCCCEEEEECCCCCHHHHHCCCCCEEEEEEEEECCCCCCCCCCC
PAQGAVYGGIVGKGAWRQNGAGRHPIAARTPPAEGITVYASRHYADDPQLAAYLARYKVA
CCCCCEECCEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
KLTNIGSALKFCRLAEGAADFYPRLGRTMEWDTAAPQAVLEAAGGRVVTMADETPLRYGK
HHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEEECCCCHHHCC
KGFENPHFLCFGRAAG
CCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]